ACS Applied Materials & Interfaces
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2015
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IF 6.723
Yuliang Jiang,Zhaoyin Wang,Zhihui Dai
A novel nanocomposite, silicon–carbon-based dots@dopamine (Si-CDs@DA) was prepared using (3-aminopropyl) triethoxysilane, glycerol, and dopamine as raw materials via a rapid microwave-assisted irradiation. This type of Si-CDs@DA exhibited ultrabright fluorescence emission (quantum yield of 12.4%) and could response to Ag+ selectively and sensitively. Moreover, the obtained Si-CDs@DA can be further applied in sensing intracellular Ag+ and cell imaging, because of its photostability, salt stability, and low cytotoxicity. This study provides a simple and efficient approach for preparing novel Ag+ fluorescent probes, which could expand the application of carbon nanomaterials in designing related biosensors.
研究领域:
纳米材料
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生物传感
·
细胞生物学
✓ 已验证
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2021
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IF 5.268
Hengxuan Li,Minghui Chen,Ran Luo,Weipan Peng,Xiaoqun Gong,Jin Chang
Ag is widely distributed in nature and it is used in almost all areas of human life. However, due to the widespread use of Ag materials, Ag + pollution seriously threatens the human health and environment. The traditional detection methods for Ag + suffer from disadvantages including high operational cost, complicated operating unit and instrument, and high requirements for professionals. Thus, in this study, a new type of Ag + detection biosensor based on the hybridization signal amplification was designed to overcome these problems. Combining cytosine-Ag + -cytosine mismatch structure with the hybridization chain reaction, this biosensor converted the conventional detection signal into the nucleic acid amplification signal, which realized efficient, rapid, sensitive, and specific detection of Ag + . The limit-of-detection of this sensor reached 0.69 pM, which is much less than the maximum concentration (0.1 mg L −1 , 927 nM) suggested for drinking water by the World Health Organization, and the maximum concentration (0.05 mg L −1 , 464 nM) suggested by the United States Environmental Protection Agency. This method provides a promising new platform for detecting Ag + concentrations at ultralow levels.
研究领域:
生物化学
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环境科学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Jince Zhang,Xiaochen Qi,Yukun Chen,Yixiang Hu,Di Fang,Taiyu Jin,Jun Wang,Dawei Fang
In this study, hydrodynamic cavitation (HC) is used as a novel and simple large-scale preparation technique. Water-soluble CdSeS alloy quantum dots (QDs) were successfully prepared by using Cd(NO 3 ) 2 ·4H 2 O, Na 2 S·9H 2 O and selenium powder as cadmium, sulfur and selenium sources. The effects of cycle time, reaction temperature, inlet pressure and Se/S molar ratio on the morphology, size and optical properties of CdSeS QDs were investigated. The prepared CdSeS QDs were characterized by X-ray diffractometer, X-ray photoelectron spectroscopy, transmission electron microscopy, UV–vis absorption spectra, fluorescence emission spectra and fluorescence attenuation curves. Finally, under the conditions of 12 h cycle time, 3.0 bar inlet pressure, 60 °C reaction temperature and 0.5/0.5 Se/S molar ratio, the ternary alloy CdSeS QDs with 2.62 nm average particle size and 482.62 ns fluorescence lifetime was obtained. Furthermore, a mechanism of preparing CdSeS QDs by using the HC method was proposed to explain the process of CdSeS precipitates conversion to CdSeS QDs. In addition, it is also found that Ag + has a quenching effect on the prepared CdSeS QDs, which means that CdSeS QDs can be used as a fluorescence probe to specifically detect Ag + . This work not only provides a new possibility for large-scale preparation of high-performance QDs but also helps to understand the mechanism of CdSeS QDs as a metal ion selective fluorescence probe.
研究领域:
材料科学
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化学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
RESEARCH ON CHEMICAL INTERMEDIATES
·
2022
·Vol. 48
·期 3
·983-1001
·
IF 3.134
Zhang Dawei,Ren Lu,Liu Ailing,Zhang Yumin,Lv Yang,Gu Qiang
Abstract An efficient synthesis of 1,3,5-trisubstituted-1 H -pyrazoles was developed via cyclocondensation in 78–92% yields starting from α , β -unsaturated aldehydes/ketones with substituted phenylhydrazine using vitamin B 1 as a catalyst, and was characterized by HR-MS, FT-IR, 1 H NMR and 13 C NMR spectroscopy. The reaction has simple operation, metal-free catalysis, acid or base free catalysis. As a green catalyst, vitamin B 1 was found to possess favorable catalytic activity and reusability for the condensation reaction. 1,3,5-trisubstituted-1 H -pyrazole shows from orange-red to cyan in different solvents when the electron withdrawing group is attached to acetophenone (taking compound 5i as an example). Compound 5i as a metal ion fluorescent probe has excellent selectivity for Ag + detection. The crystal structure of the compound 3-(4-chlorophenyl)-1,5-diphenyl-4,5-dihydro-1 H -pyrazole ( 5b ) in the orthorhombic space group Pca 21 was presented and formed racemic crystals. Graphical abstract
研究领域:
有机化学
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材料科学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2025
·
IF 2.6
Xinyan Liu,Chao Liu,Qingyue Hu,Huihui Ge,Jie Tan,Jianhua Wang,Wei Bian
It is important to be capable of achieving highly selective detection of Ag+ and Hg2+ because their excessive concentrations may pose a serious threat to human health and lead to a variety of diseases. Herein, a new type of orange fluorescent carbon dot with an emission wavelength of 590 nm was synthesized by a hydrothermal method using 1,2,4-triaminobenzene dihydrochloride and ethylenediamine as raw materials. The synthesized orange carbon dots have high affinity for Hg2+ and Ag+ ions, which can be selectively detected by fluorescence quenching with the detection limits of 0.37 nM and 0.65 nM, respectively. Moreover, the carbon dots have good fluorescence stability for the rapid detection of Ag+ and Hg2+ over a wide pH range. Importantly, the addition of EDTA reversibly restored the fluorescence intensity of the mixed solution of carbon dots and Hg2+, but not the fluorescence intensity of the Ag+-containing probe solution, which allowed for a clear distinction between Hg2+ and Ag+. In addition, the carbon dots have good biocompatibility and low toxicity to MCF-7 cells, which can be used for cell imaging and intracellular ion detection.
研究领域:
分析化学
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环境科学
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材料科学
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生物成像
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毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2018
·
IF 4.244
Bin Chen,Junjie Liu,Tong Yang,Lin Chen,Jia Hou,Changhao Feng,Cheng Zhi Huang
Ag + as one of the most commonly seen toxic heavy metal ions is involved in numerous vital biological processes, which would cause fatal damages and environmental contamination when Ag + is excessive. In the present work, CdTe quantum dots (QDs) with green, orange, and red emission capped by mercaptoacetic acid (TGA) were synthesized at one time by controlling the synthesis time and utilized for Ag + detection. Both fluorescence spectral red-shift and intensity decrease could be used for Ag + discrimination. Fluorescence lifetime , Zeta potential , and XRD, etc. were carried out to analyze the detection mechanism. Results displayed that surface passivation and electron transfer due to binding effects of Ag + to Te atom on traps of QDs could be relied on to explain the sensing mechanism. Additionally, in accordance with PCA analysis, Ag + could be also be successfully differentiated from Hg 2+ and the other metal ions. Importantly, a home-made portable device based on a 32 bit embed Micro Control Unit (MCU) system was first proposed for Ag + detection. The power supply system adopt the mini-sized lithium cell instead of the power supply system, which ensure its practical applicability. The relative position of light source and detector is set at 90° to minimize the interference. According to the detection results, the linear detection range using the device was from 5 nM to 200 nM (with a larger coefficient of determination, R 2 ), and the detection limit was calculated to be about 5 nM, which indicated that this proposed method and device could fulfil the practical application requirements.
研究领域:
环境科学
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分析化学
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材料科学
·
电气工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2018
·
IF 2.011
Yi-bao Jiang,Chao Gao,Xian Zhang,Jin-shui Yao,Qin-ze Liu,Xiao-xia Cai
A novel triphenylamine derivative, 4,4′ -bis-([1,10]phenanthrolin-2-yl) imidazo -triphenylamine (IPTPA) with an A-π-D-π-A structure, has been synthesized and characterized. The UV absorption , single and two-photon fluorescence spectra showed that IPTPA was highly sensitive to Ag + with a lower detection limit of 3.97 nmoL/L and a moderate binding constant of 2.16 × 10 5 /M at room temperature . The two-photon active cross-section of IPTPA was calculated with a value of 94.68 GM at 800 nm in the tris-HCl buffer solution. The binding mechanism between IPTPA and Ag + were explored by the Job plot, ESI-MS and 1 H NMR. The A-π-D-π-A structure of IPTPA was substituted by the A-π-D-π-D structure of IPTPA-Ag to improve the fluorescence. Furthermore, the fluorescence microscopy images indicated that IPTPA could detect Ag + in living cells.
研究领域:
分析化学
·
材料科学
·
生物医学工程
·
光学
✓ 已验证
产品关联
DOI
高影响因子
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