INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
·
2015
·
IF 1.295
Jing Zhang,Shibo Zhang,Xue Wang,Wenchang Wang,Zhidong Chen
A convenient and sensitive method was developed for the simultaneous determination of Ponceau-4R and Allura Red using an ionic liquid modified expanded graphite paste electrode (IL-EGPE). The IL-EGPE was prepared by mixing ionic liquid-expanded graphite (IL-EG) composites with solid paraffin. Based on the advantageous functions of IL and EG, IL-EGPE showed enhanced electrocatalytic activity towards the simultaneous oxidation of Ponceau-4R and Allura Red. Under optimal experimental conditions, the IL-EGPE exhibited wide linear responses to Ponceau-4R and Allura Red ranging from 6.0 to 7.5 mg L−1 and 5.0 to 0.5 mg L−1, respectively. The detection limits for Ponceau-4R and Allura Red were 1.15 and 0.89 μg L−1 at a signal-to-noise ratio of 3, respectively. The designed electrode showed good reproducibility, stability and reusability. The proposed method was successfully applied in the simultaneous determination of Ponceau-4R and Allura Red in soft drinks. This method presented a simple, rapid and sensitive platform for simultaneous determination of Ponceau-4R and Allura Red and would become a versatile and powerful tool for food safety.
研究领域:
分析化学
·
食品安全
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Electrochemical Science
·
2023
·
IF 1.5
Ting-ting Xu,Wen-chang Wang,Xiao-hui Chen,Zhi-dong Chen
In this study, a fast and convenient method to immobilize Ru(bpy) 3 2+ on glassy carbon electrode (GCE) surface is developed. A Ru(bpy) 3 2+ /poly (sulfosalicylic acid) (PSA) modified glassy carbon electrode was prepared by electrochemical polymerization and used as the working electrode in the electrochemiluminescence (ECL) detection of Allura Red (AR). Under the optimal conditions, the linear range of the method was 1.0 × 10 -7 ~ 1.0 × 10 -4 mol/L and the detection limit was 6.0 × 10 -8 mol/L. The modified electrode shows good sensitivity and stability, which can be used in the determination of Allura Red in food samples.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULAR BIOLOGY REPORTS
·
2014
·Vol. 41
·期 5
·3381-3391
·
IF 1.958
Wang Langhong,Zhang Guowen,Wang Yaping
Allura red (AR) is a widely used colorant in food industry, but may have a potential security risk. In this study, the properties of interaction between AR and human serum albumin (HSA) in vitro were determined by fluorescence, UV–Vis absorption and circular dichroism (CD) spectroscopy combining with multivariate curve resolution–alternating least squares (MCR–ALS) chemometrics and molecular modeling approaches. An expanded UV–Vis data matrix was resolved by MCR–ALS method, and the concentration profiles and pure spectra for the three reaction components (AR, HSA, and AR–HSA complex) of the system were then successfully obtained to evaluate the progress interaction of AR with HSA. The calculated thermodynamic parameters indicated that hydrogen binding and hydrophobic interactions played major roles in the binding process, and the interaction induced a decrease in the protein surface hydrophobicity. The competitive experiments revealed that AR mainly located in Sudlow’s site I of HSA, and this result was further supported by molecular modeling studies. Analysis of CD spectra found that the addition of AR induced the conformational changes of HSA. This study have provided new insight into the mechanism of interaction between AR and HSA.
研究领域:
食品科学
·
生物化学
·
药物化学
✓ 已验证
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Gege Yue,Yuan Li,Xiaozhen Wang,Yu-e Shi,Meng Jiao,Zhenguang Wang
Detection and discrimination of allura red (AR) are highly desired for food safety, which is still challenging due to the abundant of food pigments and their minor differences in optical properties. Heren, we developed a fluorescence assay for quantitative detection and discrimination of AR utilizing the dual function of sulfur nanodots (S-dots), where S-dots acted as both the fluorescence indicator and the decomposition reagents for AR. The fluorescence of S-dots was quenched by AR and gradually recovered, attributed to the decomposition effects of S-dots and etched reagents. AR was detected as low as 5 nM, and discrimination of AR was realized through observing the fluorescence recovery. The detection and discrimination of AR in practical food samples were also realized, and a portable test kit was fabricated for the on-site detection of AR. The presented work provided a new clue for designing sensors, exhibiting application potential for guarantee food safety.
研究领域:
食品安全
·
分析化学
·
生物传感
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 5
·306
·
IF 5.4
Zhu Yuchuan,Li Junhong,Yang Ruoxi,Bao Mingqiu,Hao Yakai,Chen Huijin,Yue Ruirui,Shu Jinbing,Duan Xuemin
A ternary nanocomposite, PEDOT:PSS/UiO-66-Cl@Ru, was successfully synthesized via a one-pot hydrothermal strategy for the ultrasensitive electrochemical detection of amaranth (AM) and Allura Red (AR). The conceptual advance of this work lies in the synergistic integration of halogen-induced intrinsic electroactivity, maximal atomic utilization of single-atom Ru, and the conductive bridging effect of PEDOT:PSS. This ternary design effectively overcomes the conductivity bottleneck of MOFs while delivering exceptional catalytic site density and enhanced interfacial stability. The resulting PEDOT:PSS/UiO-66-Cl@Ru platform delivered remarkable analytical performance, featuring wide linear ranges of 0.05–140 µM for AM and 0.07–50 µM for AR. The low limits of detection were 16.6 nM and 23.3 nM, with high sensitivities of 0.179 µA µM⁻¹ cm⁻² and 0.247 µA µM⁻¹ cm⁻² for AM and AR, respectively. Furthermore, the proposed sensor demonstrated excellent selectivity, reproducibility, and stability. Finally, the successful application of PEDOT:PSS/UiO-66-Cl@Ru in detecting AM and AR within beverage samples validates its practical utility for on-site food safety screening.
Section
Graphical abstract
✓ 已验证
DOI
PubMed
高影响因子
FOOD AND CHEMICAL TOXICOLOGY
·
2022
·
IF 5.572
Ke Zhang,Hui Zeng,Jingyu Feng,Zhengkun Liu,Zhenyu Chu,Wanqin Jin
Allura red (AR) is a member of azo dyes is commonly used as an additive in foods and soft drinks. However, due to the special harm of the azo structure to the human body, the dosage control of AR becomes particularly necessary. The present detection methods are time-consuming, expensive and complicated. In order to address the above issues, a core-shell nanocubes constructed sensor has been developed to determine the ultrawide detection range and selective recognition of AR with a long-term reusability. The core-shell architecture is composed of carbon material of 12.64 nm thickness covering 600 nm Mn 3 O 4 nanocube. This nanocomposite combines the advantages of Mn 3 O 4 @C, possessing high electrocatalysis and chemical stability. As confirmed in using sports drinks as real samples, the as-prepared AR sensor exhibites excellent selectivity with an ultra-wide linear range from 0.1 to 1748.4 μM, and meanwhile, this sensor can also meet the requirements of remarkable anti-interference and reusability over 30 days.
研究领域:
材料科学
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分析化学
·
食品科学
✓ 已验证
DOI
PubMed
高影响因子
Nanomaterials
·
2020
·Vol. 10
·期 2
·307
·
IF 4.324
Guangli Li,Jingtao Wu,Hongguang Jin,Yonghui Xia,Jun Liu,Quanguo He,Dongchu Chen
Titania/electro-reduced graphene oxide nanohybrids (TiO2/ErGO) were synthesized by the hydrolysis of titanium sulfate in graphene oxide suspension and in situ electrochemical reduction. It provides a facile and efficient method to obtain nanohybrids with TiO2nanoparticles (TiO2NPs) uniformly coated by graphene nanoflakes. TiO2/ErGO nanohybrids were characterized by transmission electron microscopy, X-ray diffraction, cyclic voltammogram, and electrochemical impedance spectroscopy in detail. Compared with pure ErGO and TiO2NPs, TiO2/ErGO nanohybrids greatly enhanced the electrocatalytic activity and voltammetric response of Allura Red. In the concentration range of 0.5–5.0 μM, the anodic peak currents of Allura Red were linearly correlated to their concentrations. However, the linear relationship was changed to the semi-logarithmic relationship at a higher concentration region (5.0–800 μM). The detection limit (LOD) was 0.05 μM at a signal-to-noise ratio of 3. The superior sensing performances of the proposed sensor can be ascribed to the synergistic effect between TiO2NPs and ErGO, which provides a favorable microenvironment for the electrochemical oxidation of Allura Red. The proposed TiO2/ErGO/GCE showed good reproducibility and stability both in determination and in storage, and it can accurately detect the concentration of Allura Red in milk drinks, providing an efficient platform for the sensitive determination of Allura Red with high reliability, simplicity, and rapidness.Keywords:TiO2;electro-reduced graphene oxide;Allura Red;voltammetric sensor
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2015
·Vol. 162
·期 6
·H321
·
IF 3.266
Meiling Wang,Jianwei Zhao
A facile electrochemical sensor was fabricated via highly dispersing Multi-walled carbon nanotubes (MWCNTs) in ionic liquid-graphene oxides (IL-GO) "water" at room temperature. The introduction of IL (1-butyl-3-methylimidazolium hexafluorophosphate) to GO water resulted in the high dispersibility of MWCNTs and also caused fast electron transfer rates of the three dyes of Ponceau 4R (E124), Tartrazine (E102) and Allura red (E129) at the IL-GO-MWCNT composites modified glassy carbon electrode (IL-GO-MWCNT/GCE). Well-separated oxidation peaks and enhanced peak currents of Ponceau 4R, Allura red, and Tartrazine were observed at the IL-GO-MWCNT modified GCE. For individual detection, the linear responses of Ponceau 4R, Allura red, and Tartrazine were in the concentration ranges of 1.0 × 10−9-1.0 × 10−6, 8.0 × 10−10-5.0 × 10−7, and 1.0 × 10−8-1.0 × 10−6 mol L−1 with detection limits of 8.0 × 10−10, 5.0 × 10−10, and 7.0 × 10−9 mol L−1 (S/N = 3), respectively. For simultaneous determination by synchronous change of the concentrations of Ponceau 4R, Allura red, and Tartrazine, the linear response ranges were 8.0 × 10−9-1.5 × 10−7, 5.0 × 10−9-4.5 × 10−7 and 2.0 × 10−8-1.3 × 10−7 mol L−1 with the detection limits of 6.0 × 10−9, 3.0 × 10−9, and 1.0 × 10−8 mol L−1 (S/N = 3), respectively. The fabricated sensors were further applied for the detection of Ponceau 4R, Allura, red and Tartrazine in alcoholic beverages.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
NANO
·
2015
·
IF 1.09
Desheng Xi,Xiaojuan Deng,Huijun Li,Pei Yao
Allura red (AR) is a water-soluble synthetic colorant often used as an additive in the food industry, but excess AR can be harmful to human health. In this work, we report the development of a new removal method for AR by using amino-functionalized microspheres with Fe 3 O 4 cores and twolayer shells composed of SiO 2 particles and perpendicularly aligned mesoporous SiO 2 (designated Fe 3 O 4 @nSiO 2 @mSiO 2 –NH 2 ). The material exhibits good dispersibility in aqueous solutions and a high saturation magnetization of 45.68 emu g − 1 , and can be magnetically separated efficiently with an external magnet. Importantly, the material has great adsorption capacity of 29.6 mg g − 1 for AR and the capacity for reuse with a simple treatment. The adsorption process is very fast and the kinetics data are consistent with a pseudo-second order model. Based on these, a rapid and efficient method for extraction and analysis of AR in water and soft drinks has been established.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2014
·
IF 3.259
Di Wu,Jin Yan,Jing Wang,Qing Wang,Hui Li
Binding interaction of human serum albumin (HSA) with allura red AC, a food colourant, was investigated at the molecular level through fluorescence, ultraviolet–visible, circular dichroism (CD) and Raman spectroscopies, as well as protein–ligand docking studies to better understand the chemical absorption, distribution and transportation of colourants. Results show that allura red AC has the ability to quench the intrinsic fluorescence of HSA through static quenching. The negative values of the thermodynamic parameters Δ G , Δ H , and Δ S indicated that hydrogen bond and van der Waals forces are dominant in the binding between the food colourant and HSA . The CD and Raman spectra showed that the binding of allura red AC to HSA induces the rearrangement of the carbonyl hydrogen-bonding network of polypeptides, which changes the HSA secondary structure. This colourant is bound to HSA in site I, and the binding mode was further analysed with the use of the CDOCKER algorithm in Discovery Studio.
研究领域:
生物化学
·
食品科学
·
药物化学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
·
2016
·
IF 1.411
Mingzhu Cui,Meiling Wang,Bingshe Xu,Xiaohong Shi,Dan Han,Junjie Guo
A facile route for producing reduced graphene oxide (RGO)-loaded Au nanoparticles based on ionic liquids (IL) has been proposed, in which the as-prepared RGO can be dispersed stably in water. With the assistance of IL, Au nanoparticles were uniformly and densely absorbed on the surfaces of the IL functionalised reduced graphene oxide (IRGO), forming a new composite of IRGO/Au with high dispersibility. This IRGO/Au composite enhanced its electrochemical signal obviously in the measurement of allura red in foods and exhibited a wider linear response ranging from 0.297 (0.0006 μmol L−1) to 99.3 μg L−1 (0.2 μmol L−1) with lower detection limit of 0.213 μg L−1 (0.00043 μmol L−1) at a signal-to-noise ratio of 3. To further study the practical applicability of the proposed sensor, the modified electrode was successfully applied to detect allura red in five kinds of common foods and the assay results were in a good agreement with the reference values detected by HPLC.
研究领域:
分析化学
·
食品科学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2015
·
IF 4.097
Lanlan Yu,Mengxing Shi,Xiu Yue,Lingbo Qu
A novel and sensitive electrochemical sensor for allura red determination was developed based on poly (diallyldimethylammonium chloride) (PDDA) functionalized graphene (Gr) and nickel nanoparticles (Ni) composite (PDDA-Gr-Ni). Allura red displayed remarkably increased electrochemical activity on PDDA-Gr-Ni composite modified electrode due to the synergistic effect of the large surface area and improved electron transfer efficiency of both Gr and Ni nanoparticles, which offers the feasibility for highly sensitive determination of allura red by electrochemistry method. The electrochemical properties of allura red on the modified electrode were investigated by cyclic voltammetry and differential pulse voltammetry. Under the optimum experimental conditions, the peak current of allura red was proportional to its concentration in the range of 0.05–10.0 μmol L −1 and the limit of detection (LOD) was 8.0 nmol L −1 . This simple and sensitive sensor was successfully applied to determine allura red in real sample, which provides an operational access to allura red detection in the field of food safety control.
研究领域:
分析化学
·
食品安全
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）