Frontiers of Environmental Science & Engineering
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2025
·Vol. 19
·期 7
·1-16
·
IF 6.4
Yin Wenxuan,Sun Wenjun,Yuan Yongqin,Zhang Daoyi,Zhang Yuanna,Zheng Fengyi
UV/H 2 O 2 is commonly used to remove organic micropollutants and frequently paired with activated carbon for further removal of pollutants, addressing issues such as H 2 O 2 residuals, uncontrollable by-products, and energy consumption reduction. Here, we report the changes in the removal characteristics of organic contaminants during the operation of a pilot system based on UV/H 2 O 2 coupled granular activated carbon (GAC) after in situ biofilm formation to generate biologically activated carbon (BAC). We completed the screening of unknown organic matter and molecular-level chemical transformation of 100–1600 Da dissolved organic matter (DOM) using Fourier transform high-resolution mass spectrometry (FT-ICR MS). The FT-ICR MS results indicated that BAC differs from GAC in terms of DOM removal behavior and mechanisms. GAC primarily produces free radicals through synergistic residual H 2 O 2 to further oxidize and remove organics. Low molecular weight (LMW) organics undergo general molecular chemical changes but have modest removal effects. BAC considerably lowered the chemical variety of DOM and eliminated LMW organics through biodegradation and activated carbon adsorption. According to the study findings, UV/H 2 O 2 -BAC can more effectively compensate for the drawbacks of individual technologies than UV/H 2 O 2 -GAC, with superior removal efficiency of organic pollutants, no residual H 2 O 2 , controllable effluent products, and robust performance in real environmental matrices.
研究领域:
环境科学
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水处理工程
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DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2019
·
IF 5.589
Lin Zhu,Tao Chen,Lan Xu,Zhenchao Zhou,Wanqiu Feng,Yang Liu,Hong Chen
The widespread emergence of antibiotic resistance genes (ARGs) in drinking water systems endangers human health, and may be exacerbated by their horizontal gene transfer (HGT) among microbiota. In our previous study, Quorum sensing (QS) molecules produced by bacteria from biological activated carbon (BAC) biofilms were demonstrated to influence the transfer efficiency of a model conjugative plasmid, here RP4. In this study, we further explored the effect and mechanism of QS on conjugation transfer. The results revealed that Acyl-homoserine lactones producing (AHL-producing) bacteria isolated from BAC biofilm play a role in the propagation of ARGs. We selected several quorum sensing inhibitors (QSIs) to study their effects on AHL-producing bacteria, including the formation of biofilm and the regulating effect on conjugation transfer. In addition, the possible molecular mechanisms for AHLs that promote conjugative transfer were attributable to enhancing the mRNA expression, which involved altered expressions of conjugation-related genes. We also found that QSIs could inhibit conjugative transfer by downregulating the conjugation-relevant genes. We believe that this is the first insightful exploration of the mechanism by which AHLs will facilitate and QSIs will inhibit the conjugative transfer of ARGs. These results provide creative insight into ARG pollution control that involves blocking QS during BAC treatment in drinking water systems.
研究领域:
微生物学
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环境科学
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分子生物学
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水处理工程
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DOI
PubMed
高影响因子
JOURNAL OF POLYMER SCIENCE
·
2023
·Vol. 61
·期 20
·2475-2485
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IF 3.4
Yi Wang,Yu Miao,Yuxin Cai,Enfu Wang,YiPeng Liang,Jinhuan Zhong,Wenbiao Zhang,Jingda Huang
Development of water-soluble polymer air filtration materials attracts considerable attentions due to their environmentally friendly performance and high efficiency, but the balance of mechanical strength, efficiency and pressure drop still is a severe challenge. Focusing on this issue, polyvinyl alcohol (PVA), bamboo activated carbon (BAC) and sodium lignosulfonate (Ls) were combined to construct an electrospinning system with two filtration functions. In the PVA@Ls@BAC system, the 3D network constructed by the electrospun PVA based nanofibrous could effectively intercept PM2.5, and the introduced Ls enhanced the mechanical strength of PVA nanofibrous due to its good rigidity. In addition, the added negatively charged BAC facilitated the electrostatic adsorption of PM2.5 while also improved the heat resistance of the system. Moreover, polydimethylsiloxane (PDMS) was introduced to enhance the water resistance of the system. The resulting electrospun PVA@Ls@BAC@PDMS composite nanofibrous air filtration membrane exhibited excellent air filtration performance (98.67%), water repellency (123.7° of WCA), and reusable performance, as well as having good mechanical property and the tensile fracture strain reaching 112%. Because of its good performance and simple preparation process, the electrospun PVA@Ls@BAC@PDMS composite nanofibrous air filtration membrane has great application space. Graphical
研究领域:
材料科学
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环境工程
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纳米技术
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DOI
高影响因子
Small
·
2023
·Vol. 19
·期 17
·2206936
·
IF 13.3
Jiahui Yan,Yanan Wang,Jingwen Zhang,Xiaohu Liu,Liangmin Yu,Zhiyu He
Calcium overload and ROS overproduction, two major triggers of acute kidney injury (AKI), are self-amplifying and mutually reinforcing, forming a complicated cascading feedback loop that induces kidney cell “suicide” and ultimately renal failure. There are currently no clinically effective drugs for the treatment of AKI, excluding adjuvant therapy. In this study, a porous silicon-based nanocarrier rich in disulfide bond skeleton (<50 nm) is developed that enables efficient co-loading of the hydrophilic drug borane amino complex and the hydrophobic drug BAPTA-AM, with its outer layer sealed by the renal tubule-targeting peptide PEG-LTH. Once targeted to the kidney injured site, the nanocarrier structure collapses in the high glutathione environment of the early stage of AKI, releasing the drugs. Under the action of the slightly acidic inflammatory environment and intracellular esterase, the released drugs produce hydrogen and BAPTA, which can rapidly eliminate the excess ROS and overloaded Ca 2+ , blocking endoplasmic reticulum/mitochondrial apoptosis pathway (ATF4-CHOP-Bax axis, Casp-12-Casp-3 axis, Cyt-C-Casp-3 axis) and inflammatory pathway (TNF-α-NF-κB axis) from the source, thus rescuing the renal cells in the “critical survival” state and further restoring the kidney function. Overall, this nanoparticle shows substantial clinical promise as a potential therapeutic strategy for I/R injury-related diseases.
研究领域:
纳米技术
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药学
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肾脏生理学
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分子生物学
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治疗学
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产品关联
DOI
PubMed
高影响因子
Materials
·
2019
·Vol. 12
·期 22
·3780
·
IF 2.972
Xianfeng Yue,Rong Zhang,Huairui Li,Minglei Su,Xiaobei Jin,Daochun Qin
Benzyl ammonium chloride (BAC) is a broad-spectrum bactericide, but vulnerable to leaching by water. In this paper, halloysite nanotubes (HNT) and montmorillonite (MMT) were used as drug carriers to load BAC, in order to achieve good anti-mildew activity and long-term sustained release properties. The HNT and MMT nano-composites were characterized by transmission electron microscope (TEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), and nitrogen adsorption/desorption. XRD results showed that BAC intercalated the interlayer of MMT, and expanded the interlayer spacing from 1.15 nm to 1.75 nm. Pore analysis showed that BAC decreased the cavity of halloysite nanotubes to a certain extent, which indicated that BAC loaded inside the lumen of HNT successfully. TG analysis showed that the loading capacity of MMT to BAC was higher than HNT. The accelerated-release experiments revealed both two clays have significant sustained-release effects on BAC, and the releasing rate of HNT was relatively lower. Both HNT and MMT have promising application prospects as sustained-release carriers. The inhibition test showed that BAC in nano-clay has good anti-mildew resistance performance.Keywords:Benzyl ammonium chloride;halloysite nanotubes;montmorillonite;sustained release;anti-mildew
研究领域:
材料科学
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微生物学
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DOI
PubMed
高影响因子
Frontiers of Materials Science
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2023
·Vol. 17
·期 4
·1-12
·
IF 2.7
Huang Jingda,Wang Yi,Cai Yuxin,Liang Yipeng,Lin Shite,Wang Enfu,Zhong Jinhuan,Zhang Wenbiao,Sheng Kuichuan
It is still a challenge to prepare a water- and polymer-based electrospun air filter film with high efficiency filtration, low pressure drop, and good mechanical properties. To address this issue, polyvinyl alcohol (PVA) was employed as the main material, mixing polyethyleneimine (PEI), bamboo-based activated carbon (BAC) and cellulose nanocrystal (CNC) to construct the air filter film by electrostatic electrospinning. In this system, the negatively charged BAC and CNC are fixed in the system through bonding with the positively charged PEI, showing a double adsorption effect. One is the mechanical filtration of the porous network structure constructed by PVA@PEI electrospun nanofibers, and the other is the electrostatic adsorption of PM2.5 on the surface of BAC and CNC. It is significant that the resulting composite air filter displays a high filtration efficiency of 95.86%, a pressure drop of only 59 Pa, and good thermal stability. Moreover, the introduced methyltrimethoxysilane (MTMS) endows it with good water-resistance. Given these excellent performances, this system can provide theoretical and technical references for the development of water- and polymer-based electrospun air filter film.
研究领域:
材料科学
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环境工程
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纳米技术
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DOI
高影响因子
ANALYTICAL LETTERS
·
2024
·
IF 1.6
Yigong Geng,Shun Zhang,Jing Lin,Xuchu Zhu,Wenqing Gao,Junhui Li,Chenlu Wang,Yong Wu,Renlu Han,Keqi Tang,Jiancheng Yu
Ethanol abuse is increasingly becoming a global issue, adversely affecting both society and families. In blood alcohol concentration (BAC) detection, traditional techniques have long experimental cycles and harsh experimental conditions and often fail to produce timely results. Consequently, achieving swift and precise on-site detection of ethanol poisoning in humans poses a formidable challenge in analytical science. We designed a novel assay for swift on-site analysis of ethanol and BTEX (benzene, toluene, ethylbenzene, and xylene) poisoning in humans using a custom portable headspace injector (portable HS) and portable gas chromatography-mass spectrometry (portable GC-MS). This setup, known for its lightweight design and speed, allows on-site sampling and delivers rapid results. We established a calibration curve (R2 > 0.99) for ethanol in blood using portable gas chromatography-mass spectrometry (portable GC-MS). This on-site blood alcohol concentration (BAC) assay proves simpler than traditional methods, enabling rapid analysis of each sample within a short timeframe and requiring only a small blood volume (0.1 ml). In addition to our investigation on ethanol, we developed a portable method for detecting BTEX in blood. This method provides a favorable coefficient of determination (R2 > 0.99) for various substances, thereby broadening the utility of portable mass spectrometry in areas such as traffic inspection and forensic identification.
研究领域:
分析化学
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法医学
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毒理学
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2017
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IF 3.387
Dan Lv,Yu Liu,Jiasheng Zhou,Kunlun Yang,Zimo Lou,Shams Ali Baig,Xinhua Xu
In this study, a novel bamboo activated carbon (BAC) with ethylene diamine tetraacetic acid (EDTA) functionality was prepared by direct grafting in the presence of tetraethyl orthosilicate (TEOS) as a crosslinking agent. The BAC@SiO 2 -EDTA was characterized by SEM, TEM, TGA, FTIR, XPS and its adsorption property for removal of Pb(II) and Cu(II) under various experimental conditions was also investigated. The characterization results reflected that EDTA was successfully assembled on the surface of the BAC and average pore size increased from 4.10 to 4.83 nm as BAC grafted with EDTA. Adsorption data fitted very well in Langmuir isotherm model and pseudo-second-order kinetic model. As compared with the raw BAC, the maximum adsorption capacities of BAC@SiO 2 -EDTA for the Pb(II) and Cu(II) increased from 45.45 to 123.45 mg g −1 and from 6.85 to 42.19 mg g −1 , since the existence of EDTA on modified BAC promoted the formation of chemical complex. The removal of heavy metal ions mainly depended on the complexation with EDTA and the electrostatic attractions with negatively charged surface of BAC@SiO 2 -EDTA. The adsorption of Pb(II)/Cu(II) on the BAC@SiO 2 -EDTA was pH dependent and pH 5–6 was considered an optimum. However, lower temperature favored the adsorption and the maximum adsorption was recorded at 20 °C. In addition, BAC@SiO 2 -EDTA had an excellent reusability with about 40% decline in the adsorption capacity for Pb(II) after fifth reuse. Insignificant influences of co-existing cations and natural organic matter (NOM) were found on the adsorption of Pb(II) and Cu(II). All the results demonstrate that BAC@SiO 2 -EDTA is a potential adsorbent for metal ions in wastewater.
研究领域:
环境科学
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化学工程
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材料科学
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产品关联
DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2024
·
IF 7.6
Yumeng Qi,Wenqian Cao,Ying Zhang,Ruijuan Qu,Rehab Khaled Mahmoud,Mostafa R. Abukhadra,Zongli Huo,Feng Zhu
The present study systematically investigated the elimination of benzalkonium chloride (BAC) in the zero valent iron activated persulfate (Fe 0 /PS) system. The influence of operational parameters, including PS concentration, Fe 0 dosage and pH, were investigated through a series of kinetic experiments. When the Fe 0 dosage was 5.0 mM, the initial ratio of [PS]: [BAC] was 10:1, the degradation efficiency could achieve 91.7% at pH 7.0 within 60 min. Common inorganic anions and humic acid did not significantly affect BAC degradation, implying that Fe 0 /PS system had a potential application prospect in the actual wastewater remediation. Based on the electron paramagnetic resonance test and quenching experiments, the BAC degradation was found to be contributed by •OH, SO 4 • - and Fe(IV). A total of 23 intermediates were identified by the liquid chromatography-mass spectrometry, and the degradation pathways were proposed accordingly, including dealkylation and demethylation, hydroxylation, sulfate substitution and benzyl C-N cleavage reactions. Density functional theory based calculations were conducted to realize the rationality of the proposed reaction mechanisms. The toxicity of transformation products was predicted by ECOSAR program. This work demonstrated the possibility of BAC removal in hospital and municipal wastewater by Fe 0 /PS treatment, and also provides a safe choice for deep treatment of quaternary ammonium salt wastewater.
研究领域:
环境科学
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化学工程
·
毒理学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Zhenqi Du,Naiyuan Liu,Yiran Jia,Huaiyu Zhang,Shunke Ding,Baozhen Liu,Yonglei Wang,Wenhai Chu
Cellar water DOM presented LMW, low aromaticity and high nitrogen contents. • Toxicity of disinfected cellar water is nearly 2.5 times that of surface water. • UV/SPC-BAC reduced chlorinated cellar water toxicity by nearly 75%. • UV-SPC-BAC mitigates toxicity by lowering DOM unsaturation and unknown CHONCl. Cellar water harvested from rooftops is recognized as a valuable alternative source for alleviating global water scarcity. Nevertheless, accumulated multi-source pollutants pose a high risk of toxic disinfection by-product (DBP) formation during disinfection. In this study, a pilot-scale system was established to control DBP-associated toxic risks. Compared with local surface water, simulated rooftop-harvested cellar water contained elevated organic matter (3.18 ± 0.23 mg/L), with nitrogenous organics (CHONs, CHONSs) accounting for 49.94% of total organic molecules. Accordingly, chlorinated cellar water exhibited 2.85-fold higher cytotoxicity and 2.44-fold higher genotoxicity than chlorinated surface water. Conventional coagulation-sand filtration preferentially removed high-molecular-weight CHO fractions yet leaves abundant hydrophilic nitrogenous organics uneliminated. In contrast, the ultraviolet/sodium percarbonate-biological activated carbon (UV/SPC-BAC) process drastically reduced molecules from 6687 to 3113, with marked declines in CHONs and CHONSs. Separate UV/SPC oxidation or BAC filtration reduced DBP-related toxicity by only 20.2% - 30.6%, whereas the combined UV/SPC-BAC process achieved nearly 72.0% toxicity reduction. Significant declines also occurred in the calculated additive toxicity index of known DBPs and the abundance of unknown DBPs. Mass difference analysis revealed that UV/SPC-BAC preferentially eliminates unsaturated and nitrogenous fractions, suppressing oxygen addition during post-chlorination and mitigating nitrogenous DBP formation potential and toxicity. Download: Download high-res image (214KB) Download: Download full-size image
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DOI
高影响因子
Frontiers in Microbiology
·
2020
·
IF 4.236
Lü Jin,Long Qingshan,Zhao Zhilong,Chen Lu,He Weijun,Hong Jiali,Liu Kai,Wang Yemin,Pang Xiuhua,Deng Zixin,Tao Meifeng
Bacteria of the genus Saccharopolyspora produce important polyketide antibiotics, including erythromycin A (Sac. erythraea) and spinosad (Sac. spinosa). We herein report the development of an industrial erythromycin-producing strain, Sac. erythraea HOE107, into a host for the heterologous expression of polyketide biosynthetic gene clusters (BGCs) from other Saccharopolyspora species and related actinomycetes. To facilitate the integration of natural product BGCs and auxiliary genes beneficial for the production of natural products, the erythromycin polyketide synthase (ery) genes were replaced with two bacterial attB genomic integration sites associated with bacteriophages ϕC31 and ϕBT1. We also established a highly efficient conjugation protocol for the introduction of large bacterial artificial chromosome (BAC) clones into Sac. erythraea strains. Based on this optimized protocol, an arrayed BAC library was effectively transferred into Sac. erythraea. The large spinosad gene cluster from Sac. spinosa and the actinorhodin gene cluster from Streptomyces coelicolor were successfully expressed in the ery deletion mutant. Deletion of the endogenous giant polyketide synthase genes pkeA1-pkeA4, the product of which is not known, and the flaviolin gene cluster (rpp) from the bacterium increased the heterologous production of spinosad and actinorhodin. Furthermore, integration of pJTU6728 carrying additional beneficial genes dramatically improved the yield of actinorhodin in the engineered Sac. erythraea strains. Our study demonstrated that the engineered Sac. erythraea strains SLQ185, LJ161, and LJ162 are good hosts for the expression of heterologous antibiotics and should aid in expression-based genome-mining approaches for the discovery of new and cryptic antibiotics from Streptomyces and rare actinomycetes.
研究领域:
微生物学
·
生物技术
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基因工程
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天然产物化学
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产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2023
·
IF 8.8
Jing Wang,Ling Li,Baihui Chi,Jiajia Shan,Xianliang Yi,Yang Liu,Hao Zhou
The use of disinfectants made from quaternary ammonium compounds (QACs) has greatly increased since the outbreak of SARS-CoV-2. However, the effect of QACs on wastewater treatment performance is still unclear. In this study, a commonly used QAC, i.e., benzyl dodecyl dimethyl ammonium bromide (BDAB), was added to a moving-bed biofilm reactor (MBBR) to investigate BDAB's effect on nutrient removal. When the BDAB concentration was increased to 50 mg L −1 , the ammonia removal efficiency (ARE) greatly decreased, as did the nitrate production rate constants (NPR). This inhibition was partly recovered by decreasing the BDAB concentration to 30 mg L −1 . Metagenomic sequencing revealed the functional genera present during different stages of the control (Rc) and BDAB-added reactors (Re). The enriched genera ( Rudaea , Nitrosospira , Sphingomonas , and Rhodanobacter ) in Rc mainly related to the nitrogen metabolism , while the enriched genera in Re was BDAB-concentration dependent. Functional genes analysis suggested that a lack of ammonia oxidase-encoding genes ( amo ABC) may have caused a decrease in ARE in Re, while the efflux pump-encoding genes emr E, mdf A, and opr M and a gene encoding BAC oxygenase ( oxy BAC) were responsible for BDAB resistance. The increase in the total abundance of antibiotic resistance genes (ARGs) in Re revealed a potential risk arising from BDAB. Overall, this study revealed the potential effect and ecological risks of BDAB introduction in WWTPs .
研究领域:
环境科学
·
微生物学
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污水处理
·
宏基因组学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）