ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
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2016
·Vol. 72
·期 1
·153-165
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IF 2.039
Ma Taowu,Wang Meng,Gong Shuangjiao,Tian Bin
The environmental factors are expected to affect the ecotoxicity of heavy metals in the presence of engineered nanoparticles (NPs) in aquatic ecosystems. However, in sediment scenario, little is known regarding their impacts on the ecotoxicity of co-exposure of sediment-associated heavy metals and NPs. This study evaluated the impacts of different levels of organic matter (OM) (4.8–11.6%) and pH (6–9) on the ecotoxicological effects of co-exposure of sediment-associated titanium dioxide nanoparticles (TiO 2 -NPs) and cadmium (Cd) to a freshwater gastropod Bellamya aeruginosa . The burdens of Ti and Cd and biomarkers of DNA damage, Na + /K + -ATPase, lipid peroxidation (LPO), and protein carbonylation (PC) in the hepatopancreas were determined following 21 days of exposure. At background level of OM (4.8%) in sediments, TiO 2 -NPs significantly promoted Cd accumulation in low-Cd treatments (5 mg/kg) but did not promote Cd accumulation in high-Cd treatments (25 mg/kg). At the relatively higher OM levels (7.1 and 11.6%), TiO 2 -NPs significantly enhanced Cd accumulation and toxicity as evidenced by aggravated DNA damage, decreased Na + /K + -ATPase activities, and increased LPO and PC levels. Moreover, Cd burdens in both low-Cd and high-Cd treatment were positively correlated with corresponding Ti burdens, indicating TiO 2 -NPs partially acted as carrier of Cd. At all pH levels, in low-Cd treatments, TiO 2 -NPs did not affect Cd accumulation, LPO, and PC levels but significantly enhanced DNA damage and slightly facilitated the inhibition of Na + /K + -ATPase activities. In high-Cd treatments, only at pH 9, TiO 2 -NPs significantly enhanced Cd accumulation and toxicity. Our results implied that interaction between TiO 2 -NPs and OM or pH significantly affected the accumulation and toxicity of Cd in B. aeruginosa , but the underlying mechanisms need further investigation. Additionally, it should be noted that the potential ecological risk of co-exposure of NPs and coexisting pollutants might be closely species-specific and related to environmental media.
研究领域:
环境科学
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毒理学
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产品关联
DOI
PubMed
高影响因子
Environmental Sciences Europe
·
2018
·Vol. 30
·期 1
·1-13
·
IF 4.04
Li Qian,Wang Meng,Duan Lei,Qiu Yanling,Ma Taowu,Chen Ling,Breitholtz Magnus,Bergman Åke,Zhao Jianfu,Hecker Markus,Wu Lingling
Freshwater sediments have been recognized as a long-term sink and potential source for environmental pollutants released into the aquatic ecosystems. In this study, the sediment quality of Taihu Lake, which is susceptible to anthropogenic contamination, was assessed by a combination of chemical analytical and biological end points. Specifically, the snail Bellamya aeruginosa was caged in situ at two locations representing different pollution levels for different exposure times (7, 14 and 21 days). At each of these time points, biochemical parameters, i.e., phase I biotransformation enzymes ethoxyresorufin-O-deethylase (EROD), the antioxidant enzymes superoxide dismutase and catalase, reactive oxygen species, protein carbonyl content and lipid peroxidation, were evaluated in the hepatopancreas of snails. In addition, surface sediments were collected for analysis of contaminants of concern, including inorganic pollutants, organochlorine pesticides, polychlorinated biphenyls and polybrominated diphenyl ethers.Chemical analyses revealed that sediments from Taihu Lake were contaminated with trace elements and organic pollutants. Concentrations of trace elements (Cu, Ni and As) and organochlorinated pesticides (4,4′-DDE) exceeded their corresponding threshold effect level according to the sediment quality assessment values for freshwater ecosystems in Canada, indicating that adverse biological effects may occur. All biomarkers, except EROD activity, were induced in snails during all exposure times. The integrated biomarker response index (IBR) indicated that during the initial exposure phase (7 days), B. aeruginosa were subjected to significant environmental stress, which diminished during later sampling time points.Results showed that IBR correlated well with the levels of environmental contaminants, demonstrating the applicability of this biomonitoring approach to complex environmental exposure scenarios.
研究领域:
环境科学
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毒理学
·
生态学
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DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2018
·
IF 4.61
Shaopan Bao,Jiaolong Huang,Xiawei Liu,Wei Tang,Tao Fang
Silver nanoparticles (AgNPs) are among the most widely used engineered nanomaterials and may eventually accumulate in sediments. Limited information is currently available regarding the toxicity, bioaccumulation and distribution of sediment-associated AgNPs in aquatic organisms. In the present study, a freshwater snail Bellamya aeruginosa was exposed via sediment to commercial Ag particles of four nominal sizes: 20 nm (AgNPs-20), 40 nm (AgNPs-40), 80 nm (AgNPs-80), and < 10 μm (bulk Ag), and to silver nitrate at sub-lethal concentrations (1, 10 and 100 μg Ag/g sediment). Ag burden and biomarkers of oxidative stress were assessed in different tissues of B . aeruginosa : hepatopancreas, gonad, foot and digestive tracts. All five Ag types were available for uptake by B . aeruginosa when spiked into sediment, and Ag accumulation in different tissues presented the following pattern: hepatopancreas > gonad ≈ digestive tracts > foot. Snails accumulated higher levels of Ag from aqueous Ag than from particulate Ag. In contrast, AgNPs-40 and AgNPs-80 treatments occasionally induced higher oxidative stress than aqueous Ag, indicating the significant role of nanoparticle itself in exerting toxicity. Size-dependent toxicity of AgNPs in sediment was also found, with AgNPs-20 showing lower toxicity than other Ag particles. Overall, this study demonstrated that the toxicity of sediment-associated AgNPs to B . aeruginosa varies with size and differs from aqueous Ag.
研究领域:
环境科学
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毒理学
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水生生态学
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DOI
PubMed
高影响因子
Environmental Sciences Europe
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2020
·Vol. 32
·期 1
·1-14
·
IF 5.394
Wu Lingling,Chen Ling,Zhu Lingjiao,Chen Xiaoping,Li Qian
Sediments function as a secondary and significant source of tributyltin (TBT) and triphenyltin (TPT) in aquatic ecosystems and may pose a potential threat on benthic organisms and human health. The subchronic toxicity of sediment-associated TBT or TPT to snails Bellamya aeruginosa at environmentally relevant concentrations was investigated in this study. Multiple endpoints at the biochemical [ethoxyresorufin-O-deethylase (EROD), superoxide dismutase (SOD), catalase (CAT), protein carbonyl content (PCC) and lipid peroxidation (LPO)] and transcriptomic levels were examined.TBT or TPT in sediment could induce antioxidant enzymes’ activities and result in oxidative damage in the hepatopancreas of B. aeruginosa after 28-day exposure. A transcriptomic profile of B. aeruginosa exposed to TBT and TPT was reported. CYP genes and EROD activity were sensible and reliable biomarkers for toxicity assessment of TBT or TPT in sediments. Comparative pathway analysis revealed the alteration of steroid hormone biosynthesis and retinol metabolism in B. aeruginosa after 90-day exposure to sediment-associated TBT at the concentration of 2000 ng/g dw, which might affect both reproduction and lipogenesis functions. The ubiquitin proteasome system and immune system might be the toxicity target in B. aeruginosa after exposure to sediment-associated TPT for 90 days.The results offered new mechanisms underlying the toxicity of sediment-associated tributyltin and triphenyltin.
研究领域:
环境毒理学
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分子生物学
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生态毒理学
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水生科学
✓ 已验证
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2016
·
IF 3.976
Taowu Ma,Shuangjiao Gong,Bin Tian
Copper oxide nanoparticles (CuO-NPs) may pose high ecological risks to aquatic ecosystems. While sediments are the final destinations for CuO-NPs, little is known about the potential ecotoxicity of sediment-associated CuO-NPs on freshwater deposit-feeding macroinvertebrates. The gastropod Bellamya aeruginosa was chosen as an ecotoxicological test species. Adult snails were exposed to Cu (180 μg/g dry weight (DW)) added to sediments in the form of CuO-NPs, CuO microparticles (CuO-MPs, size control), and CuSO 4 (solubility control) for 7, 14, and 28 days, Cu burdens in different tissues and biomarkers of oxidative stress were determined to understand Cu accumulation differences among tissues, potential mechanisms of Cu uptake, time-effect relationships, particle size effects, and the relative contribution of toxicity from CuO-NPs and its soluble Cu ions. There was no difference in Cu ion concentrations in porewaters between the CuO-NPs and CuO-MPs treatments. In addition, relatively low Cu ion concentrations in porewater might indicate their remarkably low solubility. The hepatopancreas and gonad of B. aeruginosa are the primary target tissues for Cu accumulation. Cu accumulation in the hepatopancreas and gonad from CuSO 4 treatments was consistently higher than that from the CuO-NPs and CuO-MPs treatments. After long-term exposure, Cu accumulation was higher from CuO-NPs than from CuO-MPs, especially, the Cu accumulation rate from CuO-NPs was greater than that from CuSO 4 . Short-term exposure to the three Cu forms caused oxidative stress to the hepatopancreas. CuO-MPs did not cause oxidative damage. Long-term exposure to CuO-NPs and CuSO 4 resulted in oxidative damage. Overall, prolonged exposure to CuO-NPs will increase the ecotoxicity risk to B. aeruginosa . Although there was no difference in Cu accumulation between the CuO-NPs and CuO-MPs treatments after 14 days of exposure, pronounced oxidative damage was caused by exposure to CuO-NPs but not to CuO-MPs, implying that toxicity of CuO-NPs could be attributed to specific nanoparticulate effects.
研究领域:
环境科学
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毒理学
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产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2021
·
IF 6.291
Jing Xiang,Ying Mi,Benxiang Luo,Shuangjiao Gong,Yingru Zhou,Taowu Ma
Modified composite biochar offers a cost-effective solution for the remediation of contaminated sediments; however, few studies have evaluated the effects of modified composite biochar amendment on the ecotoxicity of contaminated sediment based on benthic macroinvertebrates. A 21-day sediment toxicity test was conducted using the freshwater snail Bellamya aeruginosa to examine the intrinsic ecotoxicity of a novel KOH-modified composite biochar (KOH-CBC) and its efficacy for reducing the bioavailability, uptake, and ecotoxicity of perfluorooctanoic acid (PFOA). It was found that KOH-CBC is toxic to B. aeruginosa , which may be attributed to its high polycyclic aromatic hydrocarbons (PAHs) content and alkalinity. The addition of KOH-CBC to PFOA-contaminated sediments can markedly reduce the bioavailability and uptake of PFOA by more than 90% and 50%, respectively, and subsequently alleviate the toxicity of PFOA to B. aeruginosa by at least 30%. Increasing the KOH-CBC dosage is not beneficial for further mitigating the toxicity of PFOA-contaminated sediments. Our findings imply that KOH-CBC is a promising sorbent for the in-situ remediation of PFOA-contaminated sediments. Application of acidified KOH-CBC at a dosage of approximately 1–3% will be sufficient to control the ecotoxicity of PFOA; however, its long-term environmental effects should be further validated.
研究领域:
环境科学
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生态毒理学
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污染控制
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Jing Jiang,Min Liu,Dalun Xu,Tao Jiang,Jinjie Zhang
As a hypertoxic natural toxin, the risk of Microcystin-leucine-arginine (MC-LR) residues in Bellamya aeruginosa deserves more attention. Herein, employing the conventional thin-layer chromatography (TLC) technology and a novel surface-enhanced Raman scattering (SERS) substrate, a TLC-SERS chip was fabricated for the purification and quantitative detection of MC-LR in complex samples. The substrate exhibited excellent SERS performance with an enhancement factor of 6.6 × 10 7 , a low detection limit of 2.27 × 10 −9 mM for MC-LR, excellent uniformity and reproducibility, as well as a wide linear range. With the application of TLC, the MC-LR was efficiently purified and the concentration was increased to >3 times. Ultimately, recovery rates fluctuated between 93.28% and 101.66% were obtained from the TLC-SERS chip. On balance, the TLC-SERS chip has a robust capacity for achieving rapid and stable quantitative detection of MC-LR, which promises to improve the efficiency of food safety monitoring.
研究领域:
分析化学
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环境科学
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食品安全
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）