DESALINATION
·
2024
·
IF 8.3
Fan-xin Kong,Shi-yuan Zhang,Ding-wen Zhang,Ping Xia,Jin-fu Chen
Construction of covalent organic frameworks (COF) membranes on the polymeric substrate was challenging by interfacial polymerization (IP) process. In this study, COF-LZU1 membranes were fabricated by IP on the preheated PSf substrates to investigate the influence of substrate properties (i.e., pore size and porosity) on the COF-LZU1 layer formation. The substrates with tunable pore size (18.61 to 14.53 nm) and porosity (2.05 % to 0.42 %) could be obtained with the pretreating temperature of 20 °C to 50 °C. Preheated substrate altered monomer storage and diffusion, leading to the variations in crosslinking degree (14.89 % to 87.63 %) and observed thickness (142.9–575.9 nm). The preheated substrates endowed better growth conditions by inhibiting the COF-LZU1 intrusion into the substrates, and optimal COF 40°C membrane had water flux of 6.57 L m −2 h −1 , and Na 2 SO 4 rejection ratio of 90.9 %. The rejection ratio of pharmaceuticals by COF-LZU1 membranes was low due to adsorption. Correlation analysis showed that the C N bond content was unfavorable for absorption ( P < 0.05), and the increase of crosslinking and crystallinity of the COF-LZU1 layer will be beneficial to boost the pharmaceutical rejection. This work provided a facile method and valuable insight for the COF-LZU1 membrane fabrication to enhance desalination and pharmaceutical removal.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF IMMUNOLOGICAL METHODS
·
2022
·
IF 2.287
Ren Qiu,Wendi Mu,Chunyan Wu,Mengdie Wu,Jing Feng,Shengzhong Rong,Hongkun Ma,Dong Chang,Hongzhi Pan
CA125 is a tumor marker which mainly exists in ovarian, the detection for it with high sensitivity is conducive to improve the effectiveness of tumor prevention and control at early state. Multi-layer graphene oxide derivatives from graphene, and has poor conductivity and high stacked properties that limit its further application. Multi-layer reduced graphene oxide frame (MrGOF) was composed of single-layer graphene sheet and exhibited 3D structure with good dispersion, better conductivity and electrochemical properties after multi-layer graphene oxide underwent alkaline peeling and thermally reduction, the modified graphene are easy to load and combine functional groups and metal nanoparticles. Covalent organic frameworks (COFs) presents a stable frame and through covalent bond connection and has porous properties to adsorb biomolecules , which allows the immobilization of antibody molecules by the porosity and improve the sensitivity of the detection in sensing field. Through the adsorption of COFs for antibody and the probe labeled with functional graphene, we constructed a sandwich type immunosensor with the new material COF-LZU1 as the platform to anchor the CA125 first-antibody and MrGOF combined with amino group and loaded with silver nanoparticles (AgNPs) as the probe to detect tumor marker CA125. The linear range of detection was from 0.001 U/mL to 40 U/mL, with the detection limit was calculated to be 0.00023 U/mL (S/N =3). The prepared immunosensor showed a good application ability for real human serum, which can be attributed to the adsorption of COF-LZU1 for the CA125 first-antibody, and ability to deliver electrons and signal amplification of AgNPs anchored on the sheet structure of MrGOF.
研究领域:
生物传感器
·
材料科学
·
分析化学
·
癌症研究
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Zhenjie Zheng,Jingxuan Wang,Mengqi Ma,Yunpeng Xu,Da Huang,Jian Wang,Cuiying Lin,Zhenyu Lin,Fang Luo
Sensitive and selective detection of N -nitrosodimethylamine (NDMA), a highly carcinogenic environmental contaminant, is essential for public health and safety. In this study, we have developed a homogeneous electrochemiluminescence (ECL) biosensor for ultrasensitive NDMA detection by integrating Nafion-functionalized covalent organic framework (COF) with aptamer recognition and magnetic separation. The imine-linked COF (COF-LZU1) scaffold not only enables stable encapsulation of Ru(bpy) 3 2 + , but also creates a confined microporous environment that locally concentrates c (TPrA) and enhances the generation and survival of TPrA radicals, thereby amplifying the ECL signal. Nafion further improves Ru loading and ionic conductivity. Biotinylated aptamers were initially immobilized on streptavidin-coated magnetic beads (MBs) and hybridized with complementary DNA-modified Ru@COF-LZU1 to form Ru@COF-LZU1-MBs complex. Upon NDMA binding, a conformational switch releases Ru@COF-LZU1 into the solution. After magnetic separation, the ECL signal of the supernatant is measured in the presence of TPrA. This homogeneous format avoids electrode surface modification, which is commonly required in conventional Ru@COF-LZU1-based ECL sensors, offering improved reproducibility and simplified operation. The biosensor exhibits a wide linear range (100 fg/mL - 100 ng/mL) with a low detection limit of 9.11 fg/mL. This platform offers a sensitive, reproducible, and facile strategy for monitoring NDMA and similar small-molecule contaminants in complex matrices.
研究领域:
环境监测
·
分析化学
·
生物传感技术
·
纳米材料
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2022
·Vol. 194
·期 7
·3044-3065
·
IF 3.094
Qiu Ren,Dai Jianmin,Meng Lingqiang,Gao Hongmin,Wu Mengdie,Qi Feifan,Feng Jing,Pan Hongzhi
Porous carbon sphere materials have a large variety of applications in several fields due to the large surface area, adaptable porosity, and good conductivity they possess. Obtaining a steady carbon sphere using the green synthesis method remains a significant challenge. In this experiment, covalent organic frameworks (COFs) were used as a precursor and Fe 3 O 4 NPs were integrated into the precursor in order to synthesize a porous carbon sphere material using the one-step pyrolysis method. COFs have an ordered porous structure, perpetual porosity, large surface area, and low density and display good environmental tolerance. These properties make them an excellent precursor for synthesizing porous carbon sphere, which maintains good morphology at high temperatures, and it is not involved in the removal of dangerous reagent and small size restrictions during the synthesis process. In addition to the formation of a porous carbon sphere, transition metal carbon material that contains N element can be an active catalyst. The composites exhibit better activity when Fe is doped into carbon materials containing N element than that of other doped transition metals including Mn and Co. In this situation, the integration of Fe 3 O 4 NPs and N element in the COF precursor exposed the active sites of the composites and the two substances synergistically improved the electrocatalytic properties, and the composites were named Fe 3 O 4 @NPCS. The constructed Fe 3 O 4 @NPCS/GCE immunosensor was applied as a means of detecting CA19-9 antigen and presented a wide linear range from 0.00001 to 10 U/mL with a low detection limit of 2.429 μU/mL (S/N = 3). In addition, the prepared immunosensor was utilized for detecting CA19-9 antigen in the real human serum, and the recovery rates were in the range from 95.24% to 106.38%. Therefore, a porous carbon sphere prepared by COFs as a precursor can be applied for the detection of CA19-9 antigen in real samples, which could be an excellent strategy for CA19-9 antigen detection and could potentially promote the development of COF materials in various electrochemical fields.
研究领域:
分析化学
·
材料科学
·
生物传感器
·
癌症诊断
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Yiwei Pan,Zixun Li,Shusu Shen,Dapeng Liu,Ganwei Zhang
Due to its high porosity, excellent chemical stability, and low density, covalent organic frameworks have been widely researched in membrane separation technology . This study prepared COF-LZU1 PVP/PVDF membranes with different loadings of covalent organic framework (0–0.8 wt% COF-LZU1) synthesized by the room temperature method incorporated into a polyvinylpyrrolidone (PVP) /polyvinylidene fluoride (PVDF) matrix. The addition of hydrophilic COFs improved the hydrophilicity of the membrane, reducing the water contact angle on the membrane surface from 79° (PVDF membrane) to 58° (optimized membrane, M0.4). The water permeance of membranes was improved by 2.3 times by incorporating 0.4 wt% COF-LZU1 nanoparticles . Moreover, the rejection ratio for eriochrome black T (CBT), acid red (AR), congo red (CR), and methylene blue (MB) are all higher than 94.5%. Furthermore, it exhibits excellent permeance of 19.37 L·m −2 ·h −1 ·bar −1 in the mixed solution of CR and NaCl , with respective rejection of 96.3% and 1.6%. The BSA filtration test demonstrated that after three cycles, the FRR of COF-LZU1 PVP/PVDF membrane reached 91.52%. Generally speaking, incorporating COF-LZU1 into PVDF polymer matrix can lead to the preparation of membranes with excellent anti-fouling properties for dye separation and dye/salt separation purposes.
研究领域:
膜科学
·
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2021
·Vol. 13
·期 37
·4320-4327
·
IF 2.896
Ying Zhang,Yuhan Ning,Wanliang Liao,Weiping Wang,Ai-Jun Wang
In this work, COF-LZU1@PEI@Fe3O4 was synthesized by immobilization of COF-LZU1 onto the surface of polyethyleneimine-functionalized Fe3O4 nanoparticles (PEI@Fe3O4) and employed as an adsorbent for magnetic dispersive micro-solid phase extraction of tetracyclines (TCs). COF-LZU1@PEI@Fe3O4 was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and nitrogen adsorption–desorption isotherms analysis. The optimal extraction and desorption conditions were as follows: 15.00 mL sample solution (pH 7.0) extracted with 5.0 mg of adsorbent for 30 min at 30 °C, and then desorbed with 1.50 mL methanol/acetonitrile/0.02 mol L−1 oxalic acid solution (v/v, 1 : 2 : 7). Good linearities were obtained between the peak area and TC concentration ranging from 5–500 μg L−1 with correlation coefficients (R2) higher than 0.9992 and limits of detection lower than 0.51 μg L−1. The relative standard deviations (RSDs) of intra-day and inter-day were less than 5.7% and 7.4%, respectively. The developed method was successfully applied to the determination of TCs in environmental water samples with recoveries in the range of 87.0–113.8% and RSDs less than 5.1%, suggesting great potential of COF-LZU1@PEI@Fe3O4 for efficient extraction and analysis of trace TCs in water samples.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Cleaner Production
·
2024
·
IF 9.7
Liushan Jiang,Yue Zhang,Shiyu Huang,Jingwen Niu,Huanhuan Liu,Shuai Yuan,Qingxiang Zhou
Polycyclic aromatic hydrocarbons (PAHs) and sulfur-containing heterocyclic aromatic hydrocarbons (PASHs) are typical organic pollutants that are commonly present in the environment. Due to the continuous accumulation and transfer in the food chain, they will pose a significant threat to human life and health. In the present work, a new method was constructed with a ternary magnetic nanocomposite (Fe 0 @MXene@COF-LZU1) based magnetic solid phase extraction in combination with gas chromatography-tandem mass spectrometry (GC-MS/MS) for sensitive determination of them at trace level in Chinese tea samples. The magnetic nanomaterial Fe 0 @MXene@COF-LZU1 was synthesized via reduction and Schiff base reactions. The experimental results demonstrated that Fe 0 @MXene@COF-LZU1 had high adsorption ability and satisfactory chemical stability. Under the optimal experimental conditions, the method possessed good linearity in the concentration ranges of 0.0005 μgL −1 - 50 μg L −1 for dibenzothiophene (DBT), phenanthrene (PHE), fluoranthene (FLT) and pyrene (PYR), and 0.001 μg L −1 - 50 μg L −1 for 4-methyldibenzothiophene (4-MDBT) and 4,6-dimethyldibenzothiophene (4,6-DMDBT). The detection limits of this method were in the range of 0.014 ng L −1 -0.83 ng L −1 . The results of real samples demonstrated that the designed magnetic nanocomposite had a promising application prospect for measuring PAHs and PASHs.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·123941
·
IF 7.5
Mengyuan Yang,Yanling Li,Temitope Fausat Ajibade,Ziang Zhou,Zhaoping Cai,Lixiang Li,Huali Tian
Covalent organic frameworks (COFs) are effective materials for water treatment membranes due to their tunable pore structures and high compatibility. While composite modification strategies combining plant polyphenol tannic acid (TA)-Fe³⁺ and COFs show great promise for TFC membranes, they typically involve organic solvents or complex pre-modification of the fillers. In this study, a green, fully-aqueous layer-by-layer (LbL) self-assembly strategy was employed to prepare TA-Fe(COF-LZU1)/PES membranes. By exploiting the inherent synergy between the rigid crystalline channels of COF-LZU1 and the adhesive TA-Fe network, this approach directly utilizes pristine COF-LZU1 without secondary modification. Unlike conventional methods, the entire process avoids organic solvents, offering a highly sustainable technical alternative. The incorporation of COF-LZU1 significantly enhanced the membrane surface properties, with surface roughness increasing from 17.0 ± 2.2 nm to 43.8 ± 8.5 nm and the water contact angle decreasing from 77.0 ± 1.6° to 20.0 ± 1.0°, thereby substantially improving the membrane’s hydrophilicity. The TA-Fe(COF-LZU1)/PES membrane achieved a pure water permeance of 35.85 L·m - ²·h - ¹·bar - ¹, representing a 11.5% increase over the TA-Fe/PES membrane. It exhibited excellent separation performance, achieving high rejections of 98.3% for Direct Red 80, and further demonstrated robust stability in mixed dye/salt solutions. In five-cycle bovine serum albumin (BSA) tests, the membrane exhibited improved antifouling durability, yielding a flux recovery ratio of 75.5%. Additionally, it operated stably across a pH range of 4–8. This green self-assembly approach provides a practical strategy for preparing composite membranes for dye wastewater treatment.
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产品关联
DOI
高影响因子
Food Analytical Methods
·
2026
·Vol. 19
·期 6
·186
·
IF 3
Pang Jing,Meng Fangyuhe,Song Yiyun,Yu Hongmei,Chen Guosong,Liu Chang
A two-dimensional imine-linked covalent organic framework, designated as COF-LZU1, was employed as a high-performance solid-phase extraction (SPE) adsorbent for the preconcentration of trace Cd(II) from complex food matrices. Systematic investigations of adsorption kinetics and isotherms revealed that Cd(II) uptake follows a pseudo-second-order model and aligns with the Langmuir isotherm, indicating a monolayer chemisorption process. The theoretical maximum adsorption capacity reached 114.94 mg g −1 , demonstrating highly competitive performance against traditional adsorbents. Structural and spectroscopic characterizations (SEM–EDS, BET, FT-IR, XPS, and XRD) before and after adsorption confirmed that the robust performance of COF-LZU1 originates from its high specific surface area and abundant nucleophilic imine linkages (-C = N-), which serve as primary coordination sites. Supported by the Hard and Soft Acids and Bases and density functional theory simulations, the adsorption mechanism involves a synergistic interplay of electrostatic attraction, chelation, and the channel effect. Under optimized conditions, the integrated SPE-GFAAS platform achieved a highly sensitive limit of detection (3.34 ng L −1 ) and excellent precision (RSD = 1.0%). The methodology was validated using certified reference materials and real food samples, yielding excellent recoveries (94.0–104.0%). These findings underscore the significant potential of COFs-LZU1 as specialized scaffolds for the robust enrichment and quantification of trace heavy metals in food safety applications. Graphical A novel two-dimensional imine-linked covalent organic framework, designated as COF-LZU1, was initially employed in a solid-phase extraction system to adsorb trace amounts of Cd(II) from food samples. The adsorption process is identified as a sophisticated multi-step mechanism: initially, Cd(II) ions are attracted to the vicinity of the nitrogen-rich binding sites via electrostatic forces; subsequently, they migrate into the interior pores through the channel effect and are ultimately anchored via strong coordination-chelation with the imine linkages. This study underscores the potential of COF-LZU1 as a high-performance and selective platform for the separation and detection of Cd(II) in complex food matrices.
✓ 已验证
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2020
·
IF 7.183
Yi-Yi Su,Xi Yan,Yan Chen,Xiao-Jing Guo,Xing-Fan Chen,Wan-Zhong Lang
Covalent organic frameworks (COFs) have attracted great interest as advanced membrane materials due to their uniform channel structure and high porosity. In this work, COF-LZU1/PES composite membranes were prepared via interfacial polymerization (IP) process, and the thin and defectless COFs active layers were successfully grown on poly (ether sulfone) (PES) microfiltration substrates with 1,3,5-triformylbenzene (TFB) and p-phenylenediamine (PDA) as precursors. The prepared COF-LZU1/PES composite membranes exhibit a high rejection rate (>99.0%) for the dyes with molecular size above 1.5 nm and nonselective permeation for inorganic salts (<12.0%). At the same time, a water permeance above 80.0 L m -2 h -1 ·bar -1 is achieved, which is much higher than many other membranes with similar rejections. Long-term filtration demonstrates that COF-LZU1/PES membranes have good water stability. The excellent water permeance, high dyes separation performance and great stability endow COF-LZU1/PES membranes the performance of removing dyes from saline wastewater.
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产品关联
DOI
高影响因子
LANGMUIR
·
2020
·
IF 3.557
Jun Zhao,Bo Jin,Rufang Peng
Nitroaromatic explosives in wastewater are hardly degraded, which seriously endangers the ecological environment and human safety. We report a core–shell structure hybrid material (IR-MOF3@COF-LZU1) with high crystallinity and graded porosity. It is an effective visible-light-driven photocatalyst that degrades p-nitrophenol (PNP). After 3.5 h, PNP was degraded well under visible light, and it is proven that the photocatalytic degradation is efficient. In addition, this photocatalytic activity adhered to pseudo-first-order kinetics, and a possible photocatalytic mechanism was discussed in detail.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 8
·1759
·
IF 4.2
Bingyi Ma,Lei Zhong,Sheng Huang,Min Xiao,Shuanjin Wang,Dongmei Han,Yuezhong Meng
High ionic conductivity, outstanding mechanical stability, and a wide electrochemical window are the keys to the application of solid-state lithium metal batteries (LMBs). Due to their regular channels for ion transport and tailored functional groups, covalent organic frameworks (COFs) have been applied to solid electrolytes to improve their performance. Herein, we report a flexible polyethylene oxide-COF-LZU1 (abbreviated as PEO-COF) electrolyte membrane with a high lithium ion transference number and satisfactory mechanical strength, allowing for dendrite-free and long-time cycling for LMBs. Benefiting from the interaction between bis(triflfluoromethanesulonyl)imide anions (TFSI−) and aldehyde groups in COF-LZU1, the Li+transference number of the PEO-5% COF-LZU1 electrolyte reached up to 0.43, much higher than that of neat PEO electrolyte (0.18). Orderly channels are conducive to the homogenous Li-+deposition, thereby inhibiting the lithium dendrites. The assembled LiFePO4|PEO-5% COF-LZU1/Li cells delivered a discharge specific capacity of 146 mAh g−1and displayed a capacity retention of 80% after 200 cycles at 0.1 C (60 °C). The Li/Li symmetrical cells of the PEO-5% COF-LZU1 electrolyte presented a longer working stability at different current densities compared to that of the PEO electrolyte. Therefore, the enhanced comprehensive performance of the solid electrolyte shows potential application prospects for use in LMBs.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）