Journal of Essential Oil Bearing Plants
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2016
·
IF 0.313
Yong-Jie Yu,Sui Ni,Fan Wu,Wei-Guo Sang
This study was to investigate the chemical composition and the antioxidant activity of essential oils extracted from Torreya grandis cv. merrillii arils by hydro-distillation. Eighty six compounds, accounting for 96.39% of the essential oil, were identified by GC-MS. The essential oil contained 42 sesquiterpenoids (68.91%), 25 monoterpenoids (14.52%), 14 diterpenoids (12.39%), 3 ester (0.35%), 1 aliphatic ketones (0.04 %), and 1 aliphatic aldehyde (0.18%). The major components of the oil were Δ-cadinene, germacrene D, limonene, β-farnesene, cembrene, and α-pinene. Antioxidant activities of the essential oil was determined by 1,1-Diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay (IC50=17.13 mg/ml), β-carotene/ linoleic acid bleaching method (IC50=22.48 mg/ml), and thiobarbituric acid reactive species assay (IC50=13.48 mg/ml). These various antioxidant activities were compared with synthetic antioxidants (butylated hydroxytoluene and acorbic acid). Restults revealed that the essential oil possessed strong antioxidant activity, suggesting that the arils of Torreya grandis cv. Merrillii could be a bio-resource for an essential oil with antioxidant activity.
研究领域:
植物化学
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食品科学
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药用植物学
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DOI
高影响因子
BIOMEDICINE & PHARMACOTHERAPY
·
2019
·
IF 3.743
Hao Guo,Xinhuan Wan,Fengju Niu,Jujie Sun,Chenxiao Shi,Jessica Meng Ye,Changzheng Zhou
In this study, we aimed to evaluate the antiviral effect of total flavonoids extracted from Robinia pseudoacacia cv. idaho (RPTF) in vivo and its toxicity on rats with oral gavage. RPTF was prepared by percolation with 70% ethanol for 24 h and its antiviral effect on different kinds of viruses was evaluated in vitro by MTT staining. The long-term toxicity of RPTF on rats was evaluated through the detection of general behavior, body weight, food intake and related organ tissue sections of experimental animals. We found that RPTF produced significantly inhibitory effects on HSV-1 and EV-71 viruses with the therapeutic index TI values 113.8 and 46.2, respectively. Moreover, toxicity evaluation in vivo showed no significantly adverse effects in rats, indicating that RPTF was safe in use. In conclusion, we demonstrated that RPTF, natural compounds in the Chinese traditional medicine, could act as promising and effective antiviral therapeutics with relative safety in use.
研究领域:
药理学
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病毒学
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毒理学
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DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 10
·4507-4520
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IF 2.7
Luhua Wang,Yi Ren,Hongfang Zhao,Hongxia Li,Xiaohui Niu,Deyi Zhang,Haiyan Fan,Kunjie Wang
To address the water pollution problem caused by hexavalent chromium, this study took advantage of a multi-defect adsorption mechanism and constructed a multiple defect-containing type-II heterojunction material, CuS/Cv-CNNs. This material has simultaneous sulfur vacancies, copper vacancies, and carbon vacancies, which were used to accelerate the removal of chromium from wastewater. Attributed to the formation of electron-rich structures and free-moving ions by the construction of multiple defect sites, the photogenerated carriers generated by CuS/Cv-CNNs-70 were efficiently separated, and a high amount of physical Cr(VI) adsorption was achieved by electrostatic attraction and ion exchange, consistent with a Freundlich isothermal adsorption model. Studies on the adsorption thermodynamics demonstrate that CuS/Cv-CNNs-70 prefers to adsorb Cr(VI) when temperatures are raised. In addition, the removal of Cr(VI) (120 mg L−1) by CuS/Cv-CNNs-70 reached 97.10% after 60 minutes through the synergistic effect of adsorption and visible-light photocatalysis. This finding indicates that the synergistic effect between the multilocation defects stimulated the combined potential of adsorption and photocatalysis of CuS/Cv-CNNs-70 to realize the full utilization of the defects. In conclusion, this study confirms the prominent role of a multiple defect mechanism in wastewater treatment and environmental protection.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
RSC Advances
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2018
·Vol. 8
·期 39
·22095-22102
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IF 2.936
Yunfeng Ma,Lili Yang,Yong Yang,Yusi Peng,Yuquan Wei,Zhengren Huang
In this study, g-C3N4/Ag hybrid nanostructures were fabricated by facilely decorating silver nanoparticles on atmosphere-treated g-C3N4 and served as efficient SERS-active substrates. The observed significant SERS enhancement of crystal violet (CV) molecules on g-C3N4/Ag could be attributed to the high ability to concentrate target molecules through π–π stacking interactions and the near-field enhancement caused by the boosting SPR effect of the Ag NPs. The atmosphere and calcination time have a considerable impact on the SERS enhancement effect of the g-C3N4/Ag substrate. Furthermore, it took only 10 min to degrade dye molecules under visible light, and after 6 cycles the g-C3N4/Ag substrates still maintained sensitive SERS activity. This research indicates that g-C3N4/Ag hybrids can be applied as reusable SERS substrates.
研究领域:
材料科学
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光谱学
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环境科学
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产品关联
DOI
PubMed
高影响因子
Journal of Functional Foods
·
2021
·
IF 4.451
Yulian Zhu,Zongxing He,Xingyu Bao,Min Wang,Sheng Yin,Lijun Song,Qiang Peng
Ziziphus Jujuba cv. Muzao has attracted researchers for a long time, while residue of jujuba after extracted by water still contains many bioactivities. This paper presents the first study on in-depth structure analysis and its antioxidant of a pectic polysaccharide (PZJRP) separated and purified from Ziziphus Jujuba cv. Muzao residue through alkali extraction. Results of structural and morphological characterization according to high-performance gel-permeation chromatography, methylation analysis and partial acid hydrolysis etc. showed that PZJRP was composed of rhamnose, arabinose, glucose, galactose and galacturonic acid. Main chain of PZJRP including 1,2,4-linked rhamnose and 1,4-linked galacturonic acid, branches attached to C-4 of rhamnose, which suggested that PZJRP was a pectin polysaccharide belongs to rhamngalacturonan I type (RG-I). Significant antioxidant activity of PZJRP was revealed by protecting RAW264.7 cells against H 2 O 2 -induced oxidative stress. These findings demonstrated the potential of PZJRP to be a functional thickener as a novel food additive.
研究领域:
食品科学
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生物化学
·
分子生物学
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产品关联
DOI
高影响因子
MOLECULES
·
2017
·Vol. 22
·期 10
·1781
·
IF 2.861
Weizhen Huang,Yongjie Wang,Xiaoyan Jiang,Yueyue Sun,Zhongxi Zhao,Siying Li
This study was aimed to investigate the chemical composition, antioxidant activities and hepatoprotective effect of flavonoids fromZiziphus jujuba cv. Jinsixiaozao(ZJF). The composition of ZJF was analyzed by high performance liquid chromatography (HPLC) and Liquid chromatography–mass spectrometry (LC–MS), and antioxidant properties were investigated by biological assays in vitro. The hepatoprotective activity of ZJF was evaluated in acetaminophen (APAP)-treated BALB/c mice. Results indicate that ZJF displayed significant antioxidant capacity. Pretreatment with ZJF significantly decreased APAP-elevated serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and total bilirubin (TB). Activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) were enhanced with ZJF administration, while malondialdehyde (MDA) level and glutathione (GSH) depletion were reduced. Meanwhile, ZJF reversed the suppression of nuclear factor erythroid 2-related factor 2 (Nrf2) nuclear translocation, and up-regulated the protein expression of NAD(P)H: quinone oxidoreductase 1(NQO1) in liver damage mice. Furthermore, ZJF attenuated APAP-induced inflammatory mediator production, such as nitric oxide (NO), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β). Expression of p65 showed that ZJF dampened nuclear factor-κB (NF-κB) activation. The results strongly indicate that the hepatoprotective role of ZJF in APAP-induced hepatotoxicity might result from its induction of antioxidant defense via activation of Nrf2 and reduction of inflammation via inhibition of NF-κB.Keywords:Ziziphus jujuba cv. Jinsixiaozao;Flavonoids;hepatoprotective;antioxidant activity;Nrf2;anti-inflammation;NF-κB
研究领域:
药理学
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毒理学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2015
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IF 2.858
Guangpu Liu,Xinquan Liu,Yongchun Zhang,Fang Zhang,Ting Wei,Min Yang,Kaiming Wang,Yongjie Wang,Na Liu,Huiling Cheng,Zhongxi Zhao
Jujube polysaccharides have been proved to have various bioactivities. This study was designed to evaluate the chemical composition and hepatoprotective function of the polysaccharides extracted from Zizyphus jujube cv. Huanghetanzao (HJP). The composition of HJP was determined as heteropolysaccharides with galactose and arabinose being the main components. The pretreatment of mice with HJP significantly ( p < 0.01) reduced the activities of serum hepatic AST, ALT, and LDH induced by CCl 4 or acetaminophen (APAP) while the commercial liver-injury treatment drug silybin did not show any prevention effects. Mechanistic study results indicate that the administration of the CCl 4 - or APAP-injured mice with HJP enhanced SOD and GSH-Px and decreased MDA, indicating that anti-oxidation and detoxification could be the pathways for the liver protection observed. In addition, the liver prevention and treatment effects of HJP on the liver damage induced by CCl 4 or APAP obtained from the liver enzyme analyses were confirmed by the hepatic histopathology studies in mice. Therefore, HJP could be used as a prevention and treatment agent for liver injury induced by liver toxic chemicals and drugs.
研究领域:
食品科学与工程
·
医学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2016
·
IF 3.138
Li Zhang,Xinquan Liu,Yongjie Wang,Guangpu Liu,Zhen Zhang,Zhongxi Zhao,Huiling Cheng
Zizyphus jujuba has been used as a traditional Chinese medicinal herb since ancient time. Polysaccharides have been found to be important bioactive compounds in the jujube. This work was designed to investigate the physicochemical characteristics and bioactivities of polysaccharides purified from Zizyphus jujuba cv. Muzao . Water-soluble polysaccharides were extracted using an ultrasonically assisted extraction method. The purified polysaccharides (HJP) were obtained by deproteinization and decoloration. Three main fractions (HJP1, HJP2 and HJP3) were isolated using DEAE-Sepharose fast flow ion-exchange chromatography. The purified polysaccharides were found to consist of mannose, rhamnose, galactose, galacturonic acid, glucose and arabinose at various levels for different fractions. The HJP and its three main fractions displayed DPPH radical scavenging activities as well as relatively strong reducing power and HJP had stronger activities than homogeneous compositions. Moreover, the results from in vitro immunological activities studies indicated that HJP could improve the phagocytosis activity of THP-l cells and had effect on the expression of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6). In conclusion, the polysaccharides from Zizyphus jujuba cv. Muzao were discovered to have antioxidative and immunological activities.
研究领域:
药理学
·
生物化学
·
免疫学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Wen Liu,Jun Dong,Yuchong Ren,Wanting Zhou,Qingyan Han,Chengyun Zhang,Kaili Ren,Yongkai Wang,Wei Gao,Jianxia Qi
In this paper, Au-Ag alloy nanostar (Au-Ag NSt) substrates were prepared by liquid–liquid three-phase self-assembly method, and the influence of preparation conditions on their Raman activity of the substrate was explored. By adjusting the gold-silver ratios of alloy seeds and the concentration of AgNO 3 in the growth solution, it was found that the LSPR peak can be adjusted. Under the conditions of Au 1 -Ag 3 nanoparticles as seeds and 200 μL AgNO 3 solution (2 mM) as epitaxial growth solution, the prepared Au 1 -Ag 3 NSt substrate exhibits excellent SERS activity. The substrate can detect R6G and CV probe molecules with detection limits as low as 10 −11 M and 10 −10 M, respectively. Experiments have confirmed that the substrate has the characteristics of high sensitivity, good uniformity and strong stability. In addition, the substrate can detect APM molecules far below the safety standard, which further proves that the structure has excellent practical application potential as a SERS substrate.
研究领域:
材料科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Ximeng Lin,Xiaolong Ji,Min Wang,Sheng Yin,Qiang Peng
An acidic polysaccharide (SAZMP3) was isolated from jujube fruit residues by alkaline extraction and purified with DEAE-Sepharose Fast Flow and Sephacryl S-300 column chromatography. The structural characterizations of SAZMP3 were determined by high-performance gelpermeation chromatography, gas chromatography, Fourier transform infrared spectroscopy, methylation analysis, NMR spectroscopy, scanning electron microscopy, and atomic force microscopy. The results determined SAZMP3 was an acidic polysaccharide mainly contained rhamnose, galactose, and galacturonic acid with a molecular weight of 9.37 kDa and its backbone might mainly be composed of 1,4-α-D-GalA p with side chains of 1,3-β-D-Gal p , 1,3,5-linked Ara f , 1,2,4-α-L-Rha p and terminals of 1-linked Ara f , 1-linked Rha p , 1-linked Gal p by methylation and NMR analysis. Besides, SAZMP3 has shown potential antioxidant activity in scavenging free radicals suggesting that it is an antioxidant agent, which might contribute to the functional food qualities of jujube fruit.
研究领域:
食品科学
·
生物化学
·
药理学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2022
·Vol. 57
·期 6
·3385-3399
·
IF 3.612
Yu Zhang,Kexin Li,Maobin Chen,Shangling Fang,Da Zhen,Jinghua Cao,Zhengqi Wu,Ke Zhang
Summary In this study, a novel chrysanthemum polysaccharide (CP) was obtained and investigated from Chrysanthemum morifolium tea in Hubei province, China. Molecular characterisation and emulsifying properties of the CP were elucidated. The effects of different factors, including storage time, metal ions, pH value and heat treatment, were studied on the stability of emulsion. Results showed that the mean particle diameter (MPD) ( d 32 ) varied from 5.54 to 0.49 μm with the polysaccharide concentration ranging from 0.5wt% to 3.0wt%. The MPD ( d 32 ) of emulsions stabilised by chrysanthemum tea polysaccharide (ECP) was smaller than that of GA at 2wt%, and the MPD ( d 32 ) of ECP remained stable with no stratification occurred at 25 °C for 10 days. ECP also showed good stability under acidic conditions (3.0–7.0). With increase of Na + and Ca 2+ concentration, MPD( d 32 ) and zeta potential values raised significantly, from 2.24 to 7.24 μm and from −40.52 to −35.35 mV respectively. After high-temperature heat treatment, MPD ( d 32 ) and zeta potential showed no significant change, indicating ECP presented good storage stability. In conclusion, CP helped stabilised emulsions that could be used as a natural emulsifier for future application.
研究领域:
食品科学
·
植物化学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Guanwei Tao,Jiajun Li,Xinping Zhang
We report a new SERS sensor based on the hybridization of the laser-induced graphene (LIG) and silver nanoparticles (AgNPs). LIG was produced by direct laser writing on a PI film. AgNPs were produced on the LIG surface by thermal evaporation of silver. The porous-structured LIG layer increases largely the total surface area of the substrate and supplies delocalized π bonds for the enhancement of the adsorption of the target molecules to the LIG surface. Furthermore, LIG also provided the chemical enhancement mechanism. The high-density hotspots supplied by AgNPs on the LIG surface in such a hybrid scheme are the main mechanism for the SERS sensing. In particular, strong surface morphology depending on the Ag-deposition thickness and deposition rate enables modification of hydrophobicity of the SERS substrate, which gives additional channels for improving the SERS performance. Theoretical analysis on the distribution of the optical electric field facilitates the determination of the optimized Ag thickness and the deposition rate. These multifold enhancement mechanisms produced a SERS enhancement factor of 3.19 × 10 5 , which enables high-sensitivity detection of the banned dyes (CV, MG) in aquatic products. Strong Raman signals were detected with high contrast for a concentration as low as 10 −7 M. This sensor also has potentials for on-site detection in various application circumstances.
研究领域:
材料科学
·
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）