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Cd@HMCNs
ANALYTICAL BIOCHEMISTRY · 2025 · IF 2.5

Ultrasensitive detection of epinephrine by a Cd@HMCNs-based electrochemiluminescent sensor

Ziqi Wang,Yahui Ji,Nana You,Xiaoping Hu,Fangxin Du,Gen Liu

Epinephrine (EP), a vital hormone and neurotransmitter, is central to the body's fight-or-flight mechanism, boosting physical strength, mental focus, and reaction speed in high-stress scenarios. Measuring EP levels is key for analyzing stress reactions, identifying health disorders, and maintaining balanced physiological performance. In this work, we successfully synthesized cadmium-doped hollow mesoporous g-C 3 N 4 spheres (Cd@HMCNs) with a high surface area and high porosity. An electrochemiluminescent (ECL) sensor for EP detection was developed since EP can effectively suppresses the ECL emission of the Cd@HMCNs/K 2 S 2 O 8 system. The sensor successfully detected EP within the concentration range of 5.0 × 10 -10 mol·L -1 to 1.0 × 10 -5 mol·L -1 , with a detection limit as low as 1.67 × 10 -10 mol·L -1 . When applied to pharmaceutical sample testing, the proposed biosensor yielded reliable and satisfactory results.

CAS / MDL: 108-78-1
研究领域: 分析化学 · 生物医学工程 · 纳米材料科学
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