阿拉丁SCI论文搜索工具

NATURAL PRODUCT RESEARCH · 2014 · IF 1.225

A new diterpene from Clinopodium chinense

Mingliang Zhong,Haifeng Wu,Xiaopo Zhang,Guangli Sun,Guibo Sun,Shichun Yu,Xudong Xu

A new abietane diterpene, named as 3β-hydroxy-12-O-β-d-glucopyranosyl-8,11,13-abietatrien-7-one (1), together with four known flavonoids, was isolated from the hot water extract of the aerial parts of Clinopodium chinense. Their structures were determined by analysing the spectroscopic data including 1D, 2D NMR and HR-ESI-MS. Compound 1 tested against HepG-2 and A549 cancer cell lines expressed weak cytotoxicity. Cardioprotective effects of compounds 2–5 against H2O2-induced apoptosis in H9c2 cells were also evaluated; compounds 2 and 3 exhibited moderate cardioprotective effect.

CAS / MDL: 33069-62-4

研究领域: 植物化学 · 药理学 · 肿瘤学 · 心血管科学

✓ 已验证产品关联 DOI PubMed 高影响因子

查看原文查看 PubMed

JOURNAL OF FOOD PROTECTION · 2015 · IF 1.849

Chemical Composition and Insecticidal Activities of the Essential Oil of Clinopodium chinense (Benth.) Kuntze Aerial Parts against Liposcelis bostrychophila Badonnel

Heng Yu Li,Xin Chao Liu,Xu Bo Chen,Qi Zhi Liu,Zhi Long Liu

Water-distilled essential oil from Clinopodium chinense (Labiatae) aerial parts at the flowering stage was analyzed by gas chromatography-mass spectrometry. Thirty-five compounds, accounting for 99.18% of the total oil, were identified, and the main components of the essential oil of C. chinense were spathulenol (18.54%), piperitone (18.9%), caryophyllene (12.04%), and bornyl acetate (8.14%). Based on bioactivity-directed fractionation, bornyl acetate, caryophyllene, and piperitone were identified from the essential oil. The essential oil possessed fumigant toxicity against booklice (Liposcelis bostrychophila) with a 50% lethal concentration (LC 50 ) value of 423.39 μg/liter, while the isolated constituents, bornyl acetate and piperitone, had LC 50 values of 351.69 and 311.12 μg/liter against booklice, respectively. The essential oil also exhibited contact toxicity against L. bostrychophila with an LC 50 value of 215.25 μg/cm 2 . Bornyl acetate, caryophyllene, and piperitone exhibited acute toxicity against booklice with LC 50 values of 321.42, 275.00, and 139.74 μg/cm 2 , respectively. The results indicated that the essential oil and its isolated constituents have potential for development into natural insecticides or fumigants for control of insects in stored grains.

研究领域: 植物学 · 昆虫学

✓ 已验证 DOI 高影响因子

查看原文查看 PubMed

查找使用阿拉丁产品的科研文献

与阿拉丁产品相关的已发表科研成果

热门产品

A new diterpene from Clinopodium chinense

Chemical Composition and Insecticidal Activities of the Essential Oil of Clinopodium chinense (Benth.) Kuntze Aerial Parts against Liposcelis bostrychophila Badonnel