JOURNAL OF POLYMER RESEARCH
·
2023
·Vol. 30
·期 2
·1-15
·
IF 2.8
Qin Y. X.,Wang C.,Li K. Y.,Jin B. R.,Chen Y. R.,Ren L.,Zhang M. Y.,Zhang H. X.
Considering the current research background of environmental problems and shortages of petroleum resources aiming at proposing the “green” polymer blend with good degradability and properties similar to oil-based merchandise currently on the market, in the present study, two series of fully biodegradable blends consisting of PBS/P34HB (PBP) and PBS-g-GMA/P34HB (PGP) have been successfully fabricated by a simple and environmental-friendly processing methodology. In this work, the resulting biodegradable blends are in detail studied from the mechanical, thermal, crystallization, and morphology points of view. To improve the miscibility and enhance the interfacial adhesion between both phases of poly(butylene succinate) (PBS) as the matrix and poly (3-hydroxybutyrate-co-4-hydroxybutyrate) (P34HB) as the modifier, with consequent improvement in material mechanical properties, glycidyl methacrylate (GMA) is grafted on PBS via reactive blending in the process. The incorporation of 10wt% P34HB into the blend promotes a dramatic increase of 614% in the Izod impact strength. The crystallization temperature (Tc) of PGP is 87.78℃ when 30wt% P34HB is added, which is 25% higher than that of pure PBS and 11% higher than that of the PBP blend. Meanwhile, the crystallinity of PGP is 30.12%, 47%, and 37% decline compared to pure PBS and PBP, respectively. Rheological results show that storage modulus, loss modulus, and complex viscosity improve significantly with the increase of P34HB amount, indicating that the enhancement of melt strength is beneficial to the processing and forming of the materials.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Biomedical Materials
·
2020
·Vol. 15
·期 4
·045023
·
IF 3.174
Fanchen Sun,Jing Guo,Yuanfa Liu,Yue Yu
In this study, hydrophilic pullulan, which is favorable for cell adhesion, proliferation, and differentiation, was selected as a modifier for the preparation of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P(3HB-co-4HB))/pullulan nanofibers via electrospinning to improve the biocompatibility of P(3HB-co-4HB) and increase the drug loading of composite fibers. Alkyl polyglycoside was used as the emulsifying agent to promote emulsification and stabilize the P(3HB-co-4HB)/pullulan composite solution. Drug-loading property of the nanofibers with a shell-core structure is increased because gelatin was not formed into fibers via electrospinning, thereby forming a stable drug-containing gelatin solution in the core layer. Finally, P(3HB-co-4HB)/pullulan-gelatin shell-core nanofibers were prepared. The intermolecular interaction, morphology, crystallization properties, mechanical properties, morphology, sustained release, and biocompatibility of composite nanofibers were characterized. Results show that the crystallization property of P(3HB-co-4HB)/pullulan composite nanofibers increases continuously with an increase in the pullulan content. As the pullulan content increases, the strain and stress of P(3HB-co-4HB)/pullulan nanofibers increase initially and decrease later. At the mass ratio of P(3HB-co-4HB) to pullulan of 10:2, P(3HB-co-4HB)/pullulan composite nanofibers exhibit a uniform morphology with an average diameter of 590 nm and porosity of 70.71%. At this mass ratio, the P(3HB-co-4HB)/pullulan-gelatin/drug shell-core structure, which sustained a release effect for more than 180 h, has potential applications as biomaterials without cytotoxicity.
研究领域:
材料科学
·
生物医学工程
·
药学
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产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
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2011
·
IF 3.65
Yan Liang,Hongyun Liu,Kaina Zhang,Naifei Hu
N,N-diethylacrylamide (DEA) and 4-vinylpyridine (4VP) were polymerized into P(DEA-co-4VP) copolymer hydrogel films with immobilized glucose oxidase (GOD) on electrode surface with the simple one-step procedure under mild conditions, designed as P(DEA-co-4VP)-GOD. Cyclic voltammetric (CV) response of ferrocenedicarboxylic acid (Fc(COOH) 2 ) probe at P(DEA-co-4VP)-GOD film electrodes was very sensitive to environmental pH, temperature, and sulfate concentration. For example, in pH 5.0 buffers, the CV response of Fc(COOH) 2 was quasi-reversible with quite large peak heights at 25 °C for the films, showing the on state; while at pH 9.0, the peaks were greatly suppressed and the system was at the off state. This pH-sensitive on-off switching behavior of the films toward the probe was reversible and could be repeated for many times between pH 5.0 and 9.0. Similarly, the film system could be switched on-off reversibly when the temperature was changed between 25 and 39 °C, or when the concentration of Na 2 SO 4 was changed between 0 and 0.50 M. This triply responsive property could be further used to realize triply switchable electrochemical oxidation of glucose catalyzed by GOD immobilized in the films and mediated by Fc(COOH) 2 in solution. The responsive mechanism of the system was also explored and discussed. The pH-sensitive property was attributed to the electrostatic interaction between the P4VP component of the films and the probe at different pH, while the thermo- and sulfate-sensitive behavior was ascribed to the structure change of PDEA constituent of the films with temperature and Na 2 SO 4 concentration, respectively. These “smart” films combine the unique stimuli-responsive properties of both P4VP and PDEA with enzymatic reactions and may be used to fabricate a novel type of multi-controllable electrochemical biosensors based on bioelectrocatalysis.
研究领域:
生物化学
·
材料科学
·
生物传感技术
✓ 已验证
产品关联
DOI
高影响因子
POLYMER INTERNATIONAL
·
2024
·
IF 2.9
Guoqiang Wang,Xiang Chi
Poly[(3-hydroxybutyrate)- co -(4-hydroxybutyrate)] (P34HB), poly[(butylene succinate)- co -(butylene furandicarboxylate)] (PBSF) and poly(vinyl acetate) (PVAc) were melt-blended to prepare P34HB/PBSF/PVAc blends with improved ductility. The thermal properties, mechanical properties, rheological properties and morphology of the blends were systematically studied. The addition of PBSF promoted the melt crystallization of P34HB. The temperatures at 5% weight loss of the blends were higher than that of P34HB. The surface of the blends was investigated using scanning electron microscopy. The surface of P34HB was very smooth, but the surfaces of the blends were rough. PVAc can increase the compatibility between P34HB and PBSF. Compared with P34HB, the elongation at break of the blends was increased to 219.1%. © 2024 Society of Industrial Chemistry.
研究领域:
材料科学
·
高分子化学
·
生物质工程
✓ 已验证
产品关联
DOI
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2018
·
IF 5.16
Wei Wu,Haibing He,Tao Liu,Ruichao Wei,Xianwu Cao,Qijun Sun,Shishir Venkatesh,Richard K.K. Yuen,Vellaisamy A.L. Roy,Robert K.Y. Li
Lignin can be employed as a sustainable functional additive and reinforcement filler for polymers. In this work, melamine phosphate modified lignin (MAP-lignin) was synthesized as a bio-based halogen-free flame-retardant agent. The synergetic effects between MAP-lignin and rice husk ash (RHA) on the thermal stability, dynamic mechanical performance and flame-retardant properties of the poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P34HB) biocomposites were investigated. The results revealed that MAP-lignin and RHA could significantly increase the char residue and MAP-lignin had a good miscibility with P34HB. The incorporation of MAP-lignin and RHA as stiff fillers could enhance the storage modulus of the P34HB matrix. Moreover, the tensile strength and elongation at break of the P34HB/RHA composite could be improved due to the MAP-lignin could serve as a compatibilizer to improve the interaction between RHA and P34HB. Cone calorimetry data demonstrated that the addition of 30 wt% MAP-lignin and 5 wt% RHA reduced the peak heat release rate ( PHRR ) and total heat release ( THR ) of P34HB noticeably by 42.8 and 24.3%, respectively. In addition, the CO 2 production rate and CO concentration could be significantly suppressed by the addition of MAP-lignin. The enhanced flame retardancy of P34HB composite should be ascribed to the barrier effect of the increased char residue with compact and intact structure, as well as the released gases from the decomposition of melamine.
研究领域:
材料科学
·
生物工程
✓ 已验证
产品关联
DOI
高影响因子
Surfaces and Interfaces
·
2022
·
IF 6.137
Qiang Yang,Jing Guo,Yuanfa Liu,Fucheng Guan,Fanchen Sun,Xueyong Gong
In order to compound gelatin (GEL) with poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P(3,4HB)) to improve the hydrophilicity and biocompatibility, a simple and convenient method for preparing P(3,4HB)/GEL composite nanofibrous (P/G-CNF) was proposed. Alkyl Polyglycoside (APG) was used as an emulsifier to prepare a stable P(3,4HB)/GEL composite solution, and novel P/G-CNF was prepared by electrospinning. The intermolecular interaction, micromorphology and porosity, crystallization and mechanical properties , hydrophilicity and cytocompatibility of P/G-CNF were characterized. The results reveal that P(3,4HB), APG and GEL form many hydrogen bonds . When the m(P(3,4HB):GEL) is 10:2, the as-prepared nanofibrous exhibit the best micromorphology with a diameter and porosity of 604 nm and 68.33%. With the increasing GEL content, the crystallization and mechanical properties of P(3,4HB)/GEL composite nanofibrous scaffold (P/G-CNS) are further enhanced and decline after reaching the maximum. The hydrophilicity of P/G-CNS is significantly improved by introducing GEL. The cell proliferation rate of P/G-CNS is higher than 100%, of which the cytotoxicity grade is 0, indicating that it is non-cytotoxic. The P/G-CNS has excellent cytocompatibility and provides better cell attachment, growth and proliferation, showing promising application prospects for tissue regeneration and biomedical materials .
✓ 已验证
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2020
·
IF 5.88
Zetao Wang,Ke Ma,Xianfang Jiang,Jiali Xie,Peian Cai,Fuxin Li,Ruiming Liang,Jinmin Zhao,Li Zheng
Membranes used in guided bone regeneration (GBR) are required to exhibit high mechanical strength, biocompatibility, biodegradation, osteogenic and osteoinductive potential. In our study, poly(3-hydroxybutyrate- co -4-hydroxybutyrate)(P(3HB-co-4HB))/octacalcium phosphate (OCP) (P(3HB-co-4HB)/OCP) nanofibrous membranes were fabricated by electrospinning with two different P(3HB-co-4HB) to OCP ratios (P(3HB-co-4HB):OCP = 95:5 wt% and 90:10 wt%, termed P(3HB-co-4HB)/OCP(5)and P(3HB-co-4HB)/OCP (10), respectively) for GBR. The developed P(3HB-co-4HB)/OCP nanofibrous membranes were analysed for their osteogenic and osteoinductive properties using mesenchymal stem cells (MSCs) in vitro and in a calvarial bone defect rat model. The composite P(3HB-co-4HB)/OCP nanofibrous membranes showed decreased fibre size and enhanced tensile strength compared with those of P(3HB-co-4HB) nanofibrous membranes. In the in vitro studies, the P(3HB-co-4HB)/OCP membranes facilitated cell growth and osteoblastic differentiation of MSCs and were superior to P(3HB-co-4HB) membranes. After covered on the calvarial bone defects, P(3HB-co-4HB)/OCP membranes facilitated greater neobone formation than P(3HB-co-4HB) membranes did, as the result of histological evaluation and micro-CT analysis with higher bone volume/total volume (BV/TV) ratio and bone mineral density (BMD). P(3HB-co-4HB)/OCP(10) membranes with higher OCP content showed greater stiffness and osteoinductivity than P(3HB-co-4HB)/OCP (5)membranes, demonstrating the role of OCP in the composite membranes. These results indicated that electrospun P(3HB-co-4HB)/OCP nanofibrous membranes hold promise for the clinical application of GBR.
研究领域:
材料科学
·
生物医学工程
·
组织工程
·
再生医学
✓ 已验证
DOI
PubMed
高影响因子
POLYMER
·
2026
·
IF 5.1
Wan Ting Cui,Pei Zhi Zheng,Qiu Xiang Wang,Peng Cheng Hu,Shu Feng Zhou,Ao Nan Lai
To develop high-performance anion exchange membranes (AEMs) with excellent alkaline stability and high hydroxide conductivity, a series of poly(styrene-co-4-vinylpyridine) (PSD-m/n) were rationally designed and synthesized. Based on mature synthetic strategies, this work optimized a superior molecular configuration. The prepared polymers possess a flexible all-carbon backbone and adopt a side-chain grafting strategy to anchor industrial ionic liquids. Such aryl ether-free membrane architecture can effectively suppress the alkaline degradation behavior of conventional AEMs under harsh working conditions. Target quaternized AEMs (QPSD-m/n) were successfully fabricated by reacting PSD-m/n with an industrial ionic liquid 3-Bromo-N,N,N-trimethylpropan-1-aminium bromide (abbreviated as BTPA, counterion: Br − ). The content of pyridine-functionalized segments in the polymer backbone was precisely tailored by adjusting the molar feed ratio of styrene to 4-vinylpyridine, enabling a systematic investigation of the membrane structure-property relationship. The optimized QPSD-m/n AEMs exhibit desirable ion exchange capacity (IEC) of 1.53-2.13 meq g −1 , show low water uptake (WU) (15.22-31.03%) and restrict swelling ratio (SR) (10.11-23.90%) at 80 °C. The membranes achieve a high hydroxide conductivity of 58.32-90.06 mS cm −1 at 80 °C under test conditions. Moreover, the QPSD-m/n AEMs possess excellent thermal stability and optimizable alkaline durability. This work demonstrates that the QPSD-m/n membranes exhibit favorable performance and hold promising application prospects.
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Xiaofang Liu,Jiaxin Yi,Wenya Ma,Min Fan,Qingfeng Dong,Kunpeng Qian,Li Li
The gas permeability of packaging films significantly impacts the micro-environment and postharvest quality of fruits and vegetables. By regulating gas permeability to regulate the internal atmospheric composition of packaging, this method modulates the respiratory intensity and physiological metabolism of fruits and vegetables, thereby extending their postharvest shelf life. In this study, different proportions of Poly(lactic acid) (PLA)/Poly(3-hydroxybutyrate- co -4-hydroxybutyrate) (P34HB) composite films were prepared using the melt blending method, aiming to optimize the packaging microenvironment by adjusting the gas permeability of the films. The results indicate that the oxygen transmission rate of the composite film at a PLA/P34HB ratio of 20:80 was measured at 628.65 ± 7.2 cm 3 ·m −2 ·24 h −1 ·0.1 MPa, which was 90.98 % higher than that of the PLA film. The Pearson heatmap further confirmed that the permeability of the composite film had a significant impact on the preservation effect of peaches, while the influence on mechanical properties was not significant. This finding was corroborated by preservation experiments using films of different compositions, which demonstrated that the PLA20:80P34HB composite film performed the best. Specifically, it effectively slowed the loss of free water, thereby maintaining moisture content, total soluble solids content, and weight, ultimately extending the shelf life by 66.67 %.
研究领域:
食品科学与技术
·
高分子材料
·
采后生理学
·
包装工程
✓ 已验证
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Yancun Yu,Yi Li,Changyu Han,Liguang Xiao
The aim of this study is to use natural orotic acid (OA) as a sustainable, environmentally friendly additive to improve the crystallization, rheological, thermal, mechanical, and biodegradation properties of bacterially synthesized poly(3-hydroxybutyrate- co -4-hydroxybutyrate) (P34HB). OA was found to be an efficient nucleating agent for P34HB, and dramatically enhanced both non-isothermal and isothermal crystallization rates. The incorporation of OA increased nucleation density and decreased spherulite size, but had little effect on the crystalline structure. The rheological properties of the P34HB were greatly improved by the solid filler OA, particularly when a percolation network structure was formed in the blends. The thermal stability of P34HB was strongly enhanced, as exemplified by the ~23 °C increase in the onset thermal decomposition temperature ( T o ) for the blend loaded with 5 wt% OA compared to that of pure P34HB. Moreover, the yield strength and elongation at break of P34HB containing 0.5 wt% OA increased by 25% and 119%, respectively. The most intriguing result was the clear enhancement in the enzymatic hydrolysis rates of the P34HB/OA blends compared to that of neat P34HB. The synergetic improvement in these properties may be of significant importance for the wider practical application of biosourced P34HB.
研究领域:
材料科学
·
生物工程
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Particuology
·
2022
·
IF 3.251
Fang Wang,Zhuang Liu,Rui Xie,Xiao-Jie Ju,Wei Wang,Da-Wei Pan,Liang-Yin Chu
Lead(II) (Pb 2+ ) ions are toxic heavy metal ions that can accumulate in the human body through water and cause severe health problems, including neurotoxicity, nephrotoxicity, hematological toxicity and even genotoxicity effects. To remove Pb 2+ selectively and effectively from aqueous solutions, we develop a novel type of Pb 2+ -recognizable microgels with excellent adsorption capacity to Pb 2+ , which are fabricated from 4-acrylamidobenzo-18-crown-6 (B18C6Am) and N -isopropylmethacrylamide (NIPMAM) monomers by precipitation copolymerization method. The prepared poly( N -isopropylmethacrylamide- co -4-acrylamidobenzo-18-crown-6) (PNMB) microgels exhibit expanded structures, because the electron-donating methyl groups at α-carbon could descend the polarity of C O in the NIPMAM monomers and thus weaken the polymer segment···segment interactions. The expanded structures of PNMB microgels are beneficial for adsorption of Pb 2+ due to the low steric hindrance in the polymeric networks. The Pb 2+ adsorption isotherms of PNMB microgels are consistent with the Langmuir model for monolayer adsorption. The results indicate that the prepared Pb 2+ -recognizable PNMB microgels are highly promising for the selective removal of lead(II) ions from aqueous solutions.
研究领域:
材料科学
·
环境科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Xunda Hu,Shiyan Sun,Yunxuan Weng,Caili Zhang
The advancement of high-performance poly(3-hydroxybutyrate- co -4-hydroxybutyrate) (P34HB) bioplastics is limited by their inherent brittleness and narrow processing window. In this study, a novel class of reactive citrate-based plasticizers was developed by combining short-chain butyl esters with long-chain polyethylene glycol diglycidyl ether (PEGDE). Three derivatives—TE1B2, TE2B1, and TE3—were synthesized, with TE3 containing three epoxy groups for covalent network formation. Comprehensive characterization showed that TE3 significantly outperforms commercial tributyl citrate (TBC) in thermal stability ( T d- 10% = 275.3 °C vs. 179.2 °C), migration resistance (<1 % mass loss in petroleum ether), and mechanical performance (elongation at break, ε b = 51.2 %; tensile strength, σ = 15.8 MPa). The PEGDE segments of TE3 enable (1) covalent crosslinking with P34HB terminals via epoxy–carboxyl and epoxy–hydroxyl reactions and (2) topological entanglement maintaining the storage modulus of neat P34HB. This molecular architecture suppressed spherulite formation and established a stress-dissipating network, as evidenced by SEM. Rheological analysis further revealed TE3's shear-thinning behavior with high-frequency elasticity retention, enabling reliable fused deposition modeling (FDM). By overcoming the traditional strength–ductility trade-off, this work introduces a synergistic strategy combining chemical crosslinking and physical entanglement, offering new insights into covalently anchored plasticization and network dynamics in biopolymer design.
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）