Pairing dual hetero single atoms Co-Cu centers to reduce H2O2 for high-performance nanozyme sensor
Dual hetero paired single atomic catalyst (DHAC, CoCu@CN) was one-pot synthesized by a facile green method and applied as a nanozyme for the detection of H 2 O 2 . Both experimental results and theoretical calculations discover that the hetero-paired DAC realizes stronger adsorption energy and a bridge adsorption of H 2 O 2 for simultaneous 2-electron transfer, thereby offering much higher electrocatalytic activity and larger catalytic current than that of single Co atom and single Cu catalyst alone toward H 2 O 2 reduction. The CoCu@CN H 2 O 2 sensor demonstrates a wide linear detection range (0.654–7379.454 μM) and low limit of detection (LOD) of H 2 O 2 (0.047 μM), and is used successfully to in-site detect intracellular H 2 O 2 released from living cells, ensuring its practical applications in life science and medical diagnosis. This work not only discloses a scientific insight for the enhancement mechanism of the dual single heteroatomic catalyst, but also demonstrates an avenue to synthesize more efficient dual single heteroatomic catalyst for potential broad applications in energy conversion and/or sensing applications.
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