Zhenyu Guo,Haiyi Jin,Hongyu Sun,Bisheng Li,Huadong Yu,Die Ling Zhao,Hongjun Lin
Tetracycline (TC), a commonly used antibiotic in wastewater, poses environmental and health risks, thus demanding advanced catalysts for its effective removal. In this work, for the first time, we integrated cobalt ferrite (CoFe 2 O 4 ) and MXene quantum dots (MQDs) to form magnetic heterojunctions for rapid degradation of TC in the presence of peroxymonosulfate (PMS). Anchoring MQDs on the CoFe 2 O 4 nanoparticles remarkably promoted the overall degradation rate of TC to 98.2% within 20 min via both radical and non-radical pathways. The first-order kinetic constant was 0.170 min −1 , 3.5 and 15.5 times higher than that of CoFe 2 O 4 and MQDs alone, respectively. Quenching experiments revealed that the addition of p-benzoquinone (p-BQ) and furfuryl alcohol (FFA) reduced the degradation of TC within 20 min to 56.2% and 28.4%, respectively, indicating that the primary reactive oxygen species for TC degradation in the CoFe 2 O 4 /MQDs + PMS system are •O 2 − and 1 O 2 . CoFe 2 O 4 /MQDs also exhibited superparamagnetic property, which enabled their effective recovery by external magnetic field. Their reusability was verified by retaining 81.4% of catalytic efficacy in the consecutive 8th cycle. The CoFe 2 O 4 /MQDs + PMS system also exhibited excellent practicability in natural water samples as the degradation rates in both tap water and lake water environments exceeded 90%. Three potential pathways for TC degradation were proposed based on the liquid chromatography-mass spectrometry (LC-MS) characterizations and TC progressively transformed into 13 intermediates. This work may contribute to the ongoing efforts to develop advanced catalysts and strategies for mitigating the environmental impact of antibiotic pollution, offering a pathway toward sustainable and efficient water treatment technologies.
Qiancun Wang,Chuanmei Zang,Yau Kei Chan,Song Wang,Weizhong Yang,Yi Deng,Tingting Zhu,Miaomiao He
Polyetheretherketone (PEEK), as a promising alternative for hard tissue implant, still has limitations in anti-pathogens for coping with the clinical challenge. To reverse this situation, CoFe 2 O 4 /MXene nanosheets modified hydrogel was spin-coated on PEEK mediated by polydopamine to endow PEEK with favorable anti-bacterial activity. The modified PEEK implant exhibits the property of photothermal therapy (PTT) for local heat, photodynamic therapy (PDT), and chemodynamic therapy (CDT) for reactive oxygen species (ROS) accumulation to realize robust anti-pathogens. The antibacterial effect can be further enhanced by glutathione (GSH) consumption owing to the glutathione peroxides (GPx)-mimetic activity of CM2. In addition, we investigated the specific effects of the designed materials on bacteria, and the experimental results showed that constructed CM2 can lead to the DNA and protein of bacterial leakage and ATP synthesis decreased, ultimately eliminating more than 99% of bacteria. Furthermore, the sample exhibits favorable blood and cell compatibility with broad prospects in clinical application. Overall, a hydrogel coating-PEEK system with robust antibacterial properties has been manufactured in our work, which can not only exhibit compatibility, but also effectively avoid implant-related infection, which shows great promise for infectious bone defect repairment.
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