EUROPEAN POLYMER JOURNAL
·
2024
·
IF 5.8
Yutong Huo,Zheng Zhong,Shitong Liu,Shitong Sun,Weiguo Yao,Quanming Li,Yanli Dou
Considering the requirement of environmental and bio-friendliness of flame retardants, there is an urgent need to develop efficient flame retardants based on low-toxicity raw materials. Herein, a nano-fold structure DBN@CoMo-LDH was successfully synthesized by combining layered double hydroxides (LDHs) with hexagonal boron nitride (h-BN), through a sacrificial template approach involving ion-exchange interaction at atmospheric pressure. Thanks to the better compatibility and strong interfacial interactions of hybrids in matrix, epoxy resin (EP) composites can exhibit superior flame retardancy and smoke suppression without loss of mechanical properties. The enhancement and mechanism of fire safety of EP composites were investigated through cone calorimetric test, condensed-phase residue analysis, and gas-phase product analysis. Compared to EP, the peak heat release rate (pHRR), peak smoke production rate (pSPR), total smoke production (TSP), carbon monoxide production rate (COP) and carbon dioxide production rate (CO 2 P) of EP/4DBN@CoMo-LDH were reduced by 37.77 %, 62.96 %, 50.45 %, 45.71 % and 40.98 %, respectively. DBN@CoMo-LDH not only promoted the rapid generation of a dense carbon layer, but also effectively suppressed the release of gas phase products. Furthermore, it demonstrates excellent antimicrobial properties against both Staphylococcus aureus and Escherichia coli . Moreover, the unique nano-fold structure can provide a good thermal conduction path in the matrix, improving the thermal conductivity of EP. This study offers a feasible approach for designing high-performance flame retardants, and suggests their potential application in multifunctional EP composites.
研究领域:
材料科学
·
环境科学
·
生物学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2026
·
IF 9.2
Zhuohang Min,Qi Liu,Nannan Duan,Pengfei Jiang,Jingwen Yang,Ni Xu,Shouchun Ma,Chuanli Qin
Hydrogen is an ideal safe and clean energy source, which can be produced by the electrocatalytic hydrogen evolution reaction (HER). The high overpotential of HER is one of bottlenecks for practical application, thus efficient and stable electrocatalysts, especially inexpensive electrocatalysts, are being vigorously developed to facilitate the reaction. Herein, we report the rational synthesis of a non-noble transition metal electrocatalyst via combined self-assembly and ion-exchange strategy. Zeolitic Imidazolate Framework-67 (ZIF-67) was in-situ grown on the surface of polypyrrole-derived nitrogen-doped carbon nanotubes (N-CNT) through a self-assembly method and then ZIF-67 was transformed into a CoMo layered double hydroxide (CoMo-LDH) through an ion-exchange reaction. As a result, a nanocomposite with N-CNT as the core and CoMo-LDH as the shell (N-CNT@CoMo-LDH) was successfully synthesized. The optimal N-CNT@CoMo-LDH exhibits excellent HER performance with a low overpotential of 86 mV at 10 mA cm −2 in 1 M KOH, superior to ZIF-67, CoMo-LDH, N-CNT@ZIF-67 and many reported LDH-based electrocatalysts. Additionally, the N-CNT@CoMo-LDH maintains approximately 86% of its initial current density after 24-h continuous test, with an overpotential increase of only 9 mV after 3000 cycles. The improved electrocatalytic HER performance is primarily attributed to the synergistic interaction between Mo 6+ and Co 2+ /Co 3+ , facilitating the formation of active sites, and N-CNT as core to enhance electron transport rates and inhibit the stacking of CoMo-LDH nanosheets, thus exposing more active sites of CoMo-LDH. Furthermore, its HER is confirmed to be the Volmer-Heyrovsky mechanism. This work provides a promising pathway for synthesizing highly efficient and stable electrocatalysts based on inexpensive non-noble metals.
✓ 已验证
DOI
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2026
·
IF 15
Zhang Huifeng,Li Mengyang,Wang Tao,Zhu Huifen,Deng Lin,Guo Fulian,Zhang Zhihua,Hu Tingting,Liang Ruizheng,Cao Min,Li Zhangping
Cancer remains a critical global health burden, posing a severe threat to human life. Photo-sonodynamic therapy (PSDT), which combines photodynamic (PDT) and sonodynamic (SDT) modalities, has emerged as a promising strategy to overcome limitations in tissue penetration and therapeutic precision. Despite progress, the broader application of PSDT is hindered by PDT’s potential phototoxicity/limited therapeutic penetration depth and SDT’s thermal/mechanical damage under high ultrasound (US) power, as well as the complex synthesis of sensitizers and their suboptimal reactive oxygen species (ROS) generation. Here, we engineer Mg-doped defect-rich CoMo-LDH (a-CoMgMo-LDH) nanosheets via a doping-etching strategy to address these challenges, enabling on-demand treatment from superficial to deep-seated tumors. This sensitizer exhibits exceptional dual responsiveness to NIR-II light and US. It achieves a relative singlet oxygen quantum yield (1.53) superior to most reported photosensitizers, while its sonodynamic ROS yield surpasses that of commercial TiO 2 by 22.3 times and outperforms most reported sonosensitizers, ranking among the highest reported. After bovine serum albumin (BSA) functionalization, a-CoMgMo-LDH-BSA triggers ROS-driven apoptosis and immunogenic cell death under dual irradiation, effectively suppressing tumor growth and metastasis. By integrating NIR-II-enhanced PDT/SDT into a single-component platform, this work advances precision oncology with deep-tumor targeting and immune modulation, offering a transformative strategy for clinical translation. Graphical Mg-doped defect-rich CoMo-LDH (a-CoMgMo-LDH) nanosystem is engineered through doping-etching strategy as a new photo-sonosensitizer for highly efficient photo-sonodynamic therapy, which exhibits remarkable ROS generation efficiency under NIR-II/US stimulation, achieving a 1 O 2 quantum yield of 1.53 under NIR-II light irradiation and 22.3 times ROS yields that of commercial TiO 2 under US irradiation, respectively. After bovine serum albumin (BSA) modification, a-CoMgMo-LDH-BSA efficiently kills cancer cells and eliminates tumors by inducing dual-modal ROS generation and immunogenic cell death
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2021
·
IF 5.097
Xiao Chen,Jian Cui,Shuaining Wu,Xifeng Xia,Luyu Yang,Dongping Sun,Xuran Xu,Xufei Zhu
Electrochemical sensing is a widely adopted technique for the detection of target molecules even at a trace concentration. The key component in an electrochemical sensor is the electrode, for which layered double hydroxides (LDHs) have received significant attention because of their compositional tunability. However, it is still challenging to achieve mass production of LDHs as electrodes with structural integrity and regularity. Here, using Co-based metal organic frameworks (ZIF-67) as the precursor, a template-sacrificing strategy is reported to synthesize hollow CoMo-LDH (hCoMo-LDH) nanopolyhedra, which was used as a self-supporting electrode for electrochemical sensing. Using nitrite as the target, our hCoMo-LDH/CC electrode exhibits an ultralow detection limit (0.01 μM), a wide linear range (1 to 1500 μM), and a striking sensitivity (1020 μA·mM–1·cm–2). Density functional theory calculations were employed to obtain a mechanistic understanding on the exceptional performance of the hCoMo-LDH nanopolyhedra resulted from the Mo doping. Furthermore, the electrode demonstrates excellent stability, strong anti-interference property, and good suitability in real water samples. Our work provides more opportunities for the design of self-supporting electrode in electrochemical sensing applications.
研究领域:
材料科学
·
电化学
·
纳米技术
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2024
·
IF 13
Rong Chen,Tingting Hu,Yu Lu,Shuqing Yang,Min Zhang,Chaoliang Tan,Ruizheng Liang,Yuji Wang
Photodynamic therapy (PDT) is demonstrated to be effective in inducing antitumor immune responses for tumor metastasis treatment. However, tumor hypoxia, inferior tissue penetration of light, and low singlet oxygen ( 1 O 2 ) quantum yield significantly hamper the efficacy of PDT, thus weakening its immune function. Moreover, PDT-mediated neutrophil extracellular traps (NETs) formation can further reduce the therapeutic effectiveness. Herein, the use of defect-rich CoMo-layered double hydroxide (DR-CoMo-LDH) nanosheets as a carrier to load a typical peptidyl arginine deiminase 4 inhibitor, i.e., YW4-03, to construct a multifunctional nanoagent (403@DR-LDH) for PDT/immunotherapy, is reported. Specifically, 403@DR-LDH inherits excellent 1 O 2 generation activity under 1550 nm laser irradiation and improves the half-life of YW4-03. Meanwhile, 403@DR-LDH plus 1550 nm laser irradiation can stimulate immunogenic cell death to promote the maturation of dendric cells and activation/infiltration of T cells and significantly downregulate H3cit protein expression to inhibit NETs formation, synergistically promoting the antitumor metastasis effect. Taken together, 403@DR-LDH can kill cancer cells and inhibit tumor growth/metastasis under 1550 nm laser irradiation. Single-cell analysis indicates that 403@DR-LDH can regulate the ratio of immune cells and immune-related proteins to improve the tumor immune microenvironment, showing strong efficacy to inhibit the tumor growth, metastasis, and recurrence.
研究领域:
癌症研究
·
纳米技术
·
免疫治疗
·
光动力疗法
·
肿瘤生物学
·
分子生物学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）