Due to its excellent bone conductivity and drug adsorption as well as pH-responsive drug release property, hydroxyapatite (HAp) is widely used as a drug carrier in bone repair field. Here, we report for the first time a novel multi-functional polydopamine (PDA) coated Cu/F-codoped HAp (Cu/F-HAp-PDA) hollow microspheres . Both Cu 2+ and F - were successfully doped into the lattice of HAp and uniformly distributed in the shell of hollow microspheres through a one-step hydrothermal synthesis . Then PDA was coated homogeneously on the outer layer of Cu/F-HAp hollow microspheres. Both Cu/F-HAp and Cu/F-HAp-PDA samples displayed high drug loading efficiency and pH responsive drug release behavior. Moreover, the obtained Cu/F-HAp-PDA hollow microspheres exhibited excellent photothermal conversion efficiency and photothermal stability. The molecular dynamics simulations showed that PDA and HAp can form mutual binding mainly through Ca-O bonding, while doxorubicin (DOX) is mainly bound to PDA molecules through hydrogen bonding and π-π stacking interaction.
This work focuses on the improvement on the electrochemical performances of Fe–Mn based oxides as cathode for sodium ion batteries by doping Cu and F elements. The synthesized doped-compounds exhibit extremely excellent electrochemical performance. For instance, it's initial discharge capacity can reach 195.6 mAh g −1 at a current density of 10 mA g −1 . Meanwhile, after 200 cycles at 200 mA g −1 , it still remains a capacity of 124.1 mAh g −1 , 87.8% of the initial capacity of 141.3 mAh g −1 . More significantly, it can deliver a high capacity of 106.4 mAh g −1 at a high current density of 1000 mA g −1 . It is found that F/Cu co-substitution obviously improve the discharge capacity and cycle stability of Fe–Mn based oxide especially at higher current densities. Doping Cu and F elements has influence on the structure and morphology of the material, which results in the improvement of charge-discharge characteristics.
危险品化学品经营许可证（带存储）