Sensitive detection of ammonia in the environment is crucial due to its potential danger to human ecology and health. In gas detection technology, resistive sensors utilizing golden cross finger electrodes combined with gas-sensitive materials are commonly employed. In this study, we demonstrated a room-temperature sensor for ambient ammonia detection. The sensor is composed of two-dimensional layer-stacked metal-organic framework (MOF) Cu 3 (HITP) 2 nanomaterials drop-coated onto gold-forked finger electrodes. Density-functional theory simulation (DFT) and sensor gas-sensitive performance testing were conducted for characterization. The sensor exhibited high sensitivity, selectivity, low detection limit, excellent reproducibility, and stability. This can be attributed to the abundant Cu active sites exposed in the hexagonal ring and layer-stacked framework structure of Cu 3 (HITP) 2 nanomaterials. Ammonia adsorption leads to electron transfer into the Cu 3 (HITP) 2 framework, resulting in decreased sensor resistance. Real-time monitoring of sensor resistance changes enabled quantitative analysis. Results showed a 91.4 % response of the Cu 3 (HITP) 2 sensor to 100 ppm NH 3 , with response and recovery times of 26 s and 20 s, respectively. The sensor's limit of detection (LOD) was approximately 15 ppb. The sensor exhibited a relatively high response to NH 3 at 25 °C, as demonstrated by dynamic gradient test curves. These findings suggest that constituting a room-temperature ammonia sensor by uniformly drop-coating Cu 3 (HITP) 2 onto a gold-forked finger electrode is a feasible strategy.
Monitoring small amount of dopamine (DA) and acetaminophen (ACOP) in biological samples is of great significance for the early prevention of neurological diseases and safe use of medicines in clinical research. A novel electrochemical sensor based on conductive metal organic framework Cu 3 (HITP) 2 (HITP=2,3,6,7,10,11-hexaiminotriphenylene) and electrochemical reduced graphene oxide nanocomposite (denoted as Cu 3 (HITP) 2 /ERGO) was designed for simultaneous determination of DA and ACOP with enhanced sensitivity and selectivity. The Cu 3 (HITP) 2 /ERGO nanocomposite was characterized by scanning electron microcopy, energy dispersive spectroscopy and Fourier infrared spectroscopy. The oxidation potential separation of DA and ACOP achieved 226 mV. The Cu 3 (HITP) 2 /ERGO/GCE exhibited excellent electrochemical response towards the oxidation of DA and ACOP due to the superior conductivity and synergistic catalytic activity of Cu 3 (HITP) 2 /ERGO nanocomposite. The detection limits were 9 nM and 14 nM (S/N=3) for DA and ACOP with wide linear range of 0.05-150 μM and 0.1-100 μM, respectively. Furthermore, the proposed sensor has been successfully applied in the simultaneous detection of DA and ACOP in serum sample.
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