JOURNAL OF MEMBRANE SCIENCE
·
2024
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IF 8.4
Jingtong Yu,De Sun,Dongmin Yue,Bingbing Li,Tie Zhu,Peixiang Liu
One of the most promising desalination techniques is photothermal membrane distillation (PhMD). The research focus of PhMD technology is material renewal and structural design. Herein, the CuMOF-PVDF photothermal membranes were designed for PhMD. Firstly, a combination of chemical plating and oxidation was used to generate Cu(OH) 2 nanowires (NWs) onto the PVDF membrane. Then, the ligands were chemically bonded with Cu(OH) 2 NWs to grow the photothermal layer formed by the CuMOF hierarchical structure (CMHS). Under sunlight irradiation, the light was trapped in the CMHS, amplifying absorption and conversion of light. The CuMOF-PVDF membrane with the match-like CMHS absorbed 88.6 % of the light, resulting in a surface temperature of 74.3 °C after 600s. Moreover, by reducing the evaporation enthalpy of water, the performance of the CuMOF photothermal layer was comprehensively improved, realizing a water evaporation rate of 1.55 kg‧m −2 ‧h −1 and a high photothermal conversion rate of 71.4 %. During the PVMD process, the feed solution in the CuMOF photothermal layer was fully heated and supplied to the vaporization area, weakening the temperature polarization. Consequently, the flux of the CuMOF-PVDF membrane was 3.07 kg‧m −2 ‧h −1 and a 99.9 % rejection rate, corresponding to an energy efficiency of 85.2 %. The CuMOF-PVDF membrane is an efficient tool for PhMD, helping to advance desalination technologies.
研究领域:
材料科学
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环境工程
·
能源技术
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2020
·
IF 3.232
Shiqi Wang,Li Wang,Yongmei Zhu,Yonghai Song
The detection of S 2− is of great significance because excess S 2− can lead to a variety of serious physiological diseases. Here, two metal-organic frameworks (MOFs), ZnMOF-74 and CuMOF-74, were synthesized by using 2,5-dihydroxy terephthalic acid with strong fluorescence as organic ligand and Zn 2+ or Cu 2+ as central coordination ions for S 2− detection. Both as-prepared ZnMOF-74 and CuMOF-74 displayed nanospheres with a diameter of about 100 nm. Under the excitation of 353 nm, the ZnMOF-74 had a characteristic emission peak at 537 nm and the CuMOF-74 had a characteristic emission peak at 528 nm under excitation of 356 nm. The interaction of S 2− and Zn 2+ weakened the fluorescence of ZnMOF-74 but the interaction of S 2− with Cu 2+ to form CuS restored the fluorescence of CuMOF-74, so the ZnMOF-74 and CuMOF-74 were exploited as a fluorescent nanosensor for sensing S 2− . The ZnMOF-74 sensor has a good linear range of 19.6 nmol L −1 -90.0 μmol L −1 , and the limit of detection was as low as 6.53 nmol L −1 . The CuMOF-74 sensor has a good linear relationship with I I 0 in the S 2− concentration range of 1.50 nmol L −1 -125 μmol L −1 , and the limit of detection was 1.50 nmol L −1 . The proposed ZnMOF-74 and CuMOF-74 sensor could also detect S 2− in actual samples.
研究领域:
材料科学
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分析化学
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生物医学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Huizhi Wu,Zunpeng Hu,Qian Geng,Zihao Chen,Yuqian Song,Jiaqi Chu,Xin Ning,Senjie Dong,Ding Yuan
In this study, a multifunctional polyetherimide (PEI) nanofiber membrane decorated by Cu-based metal-organic framework (CuMOF) was proposed for high-efficient filtration/separation in complex environments. In the presence of CuMOF, the hybrid nanofiber membrane exhibited effective antibacterial ability, lotus leaf-like self-cleaning function, and enhanced particulate matter (PM) capture capacity. Significantly, the removal efficiency of resultant membrane for PM of 0.3 µm, 0.5 µm and 0.8 µm was as high as 99.94 %, 99.95 % and 99.99 %, respectively, and the filtration efficiency for particles of ≥ 1.25 µm could reach nearly 100 %. Due to the excellent stability of PEI and CuMOF, the hybrid nanofiber membrane maintained a high removal ability after high temperature (up to 200 °C), acidic and alkaline treatment, and still displayed outstanding recyclability and long-term purification capacity in seriously PM polluted level of > 800 µg/m 3 . Furthermore, the special selective wettability of hydrophobicity and lipophilicity , as well as the structural stability, enabled the obtained membrane present superior oil/water separation efficiency even in highly salty, acidic and alkaline environments. This work provides a facile and effect approach for the development of comprehensive nanofiber material for various filtration and separation applications.
研究领域:
材料科学
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环境科学
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生物学
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产品关联
DOI
高影响因子
Advanced Science
·
2025
·
IF 14.1
Ke-Juan Meng,Xinwen Ma,Kunyu Xiong,Xiaoxia Ma,Iftikhar Hussain,Momang Tian,Kaili Zhang
Hybrid materials with tunable properties, particularly metal-organic frameworks (MOFs)@MXene composites have emerged as a cutting-edge research focus different applications. In this study, a novel energetic CuMOF composed of Cu 2+ and 3-(tetrazol-5-yl) triazole is synthesized, followed by the development of CuMOF@MXene composites (CuMOF@MX x ) via a facile one-step hydrothermal method. This approach leverages the interfacial “Ti─O···Cu” non-bonded interactions to achieve composites with diverse morphologies. Subsequently, both experiments and theoretical calculations verify the presence of these non-bonded interactions and their influence on morphology, thermal property, and combustion performance of the composites. The morphologies of composites transition from a flower-like structure to a spherical shape with the addition of Ti 3 C 2 T x MXene. Furthermore, simultaneous thermogravimetry-differential scanning calorimetry tests, along with non-isothermal kinetic analysis, indicate that CuMOF@MX 4 has a higher initial temperature of 354.2 °C for runaway reaction and a larger activation energy of 211.58 kJ mol −1 , compared to CuMOF (314.9 °C and 202.56 kJ mol −1 ). In addition, the combustion tests demonstrate that CuMOF@MX x exhibit more intense and rapid combustion. This work demonstrates the critical role of the non-bonded interaction between CuMOF and Ti 3 C 2 T x interfaces in regulating the structure and properties of the composites, and the possible mechanism of this process is also elucidated.
研究领域:
材料科学
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纳米技术
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无机化学
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物理化学
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能源材料
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Mohamed Bahri,Zina Fredj,Peiwu Qin,Mohamad Sawan
Detecting preinvasive tumors before the onset of advanced clinical symptoms represents a critical advancement in improving the efficacy of early medical interventions and reducing cancer-related mortality rates. Immunosensors have emerged as the preferred choice for analyzing oncomarkers and meeting the ever-increasing demands of medical diagnostics. Therefore, the quest for the development of highly specific and sensitive immunosensors remains most sought-after to open new avenues for personalized healthcare and medical monitoring. Here, we report amplification-free and nonlabeled DNA framework-coupled AuNPs@CuMOF for ultrasensitive and highly specific electrochemical detection of carcinoembryonic antigen (CEA). Upon the CEA concentration variation from 0.0001 to 200 ng mL–1, the proposed biosensor led to a limit of detection (LOD) of 0.25 pg mL–1, surpassing most previously published CEA biosensors that rely on amplification-free methods and aligns with those based on amplification techniques. Furthermore, the suggested CEA immunosensor demonstrated auspiciously high specificity and sensitivity in detecting CEA in human serum comparable to the commercial ELISA within a relative error falling between 6.25% and 2.26%. The proposed analytical approach, hinging on the synergy effect of the CuMOF’s large surface area and the mechanical rigidity of the three-dimensional tetrahedron DNA structured probes (3D TDNA), obviously broadens the potential of immunosensors, offering higher sensitivity and lower LOD. Therefore, this work is not only an expansion of CuMOF exploitation in electrochemical biosensing but also a major milestone in detecting diverse biomarkers in clinical settings for tumor diagnosis.
研究领域:
生物医学工程
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分析化学
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医学诊断
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癌症研究
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生物传感器
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产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2023
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IF 3.3
Heng Zhao,Junhua Sun,Yanjie Du,Miaomiao Zhang,Zhen Yang,Jianhui Su,Xiujing Peng,Xiaolei Liu,Guoxin Sun,Yu Cui
Lead is a toxic heavy metal that is highly harmful to humans. Developing fast, efficient, and separable materials to treat lead-contaminated wastewater is challenging. In this paper, Cu-based MOF composite (SCC-CuMOF) was prepared by in-situ growth method and used for the removal of Pb 2+ from aqueous solutions. The obtained materials were characterized by field emission scanning electron microscope (FESEM), energy dispersive spectroscopy (EDS) mapping, Brunauer-Emmett-Teller (BET) specific surface area, X-ray diffraction (XRD) and infrared spectroscopy (IR). The effects of pH, coexisting ions, contact time, initial ion concentration, and temperature on the removal of Pb 2+ were investigated. SCC-CuMOF exhibited excellent adsorption performance on Pb 2+ . Adsorption of Pb 2+ on SCC-CuMOF were in accordance with the pseudo-second-order model and Langmuir model. The adsorption thermodynamic study suggested that the adsorption process was spontaneous and endothermic. The results revealed that Pb 2+ might be adsorbed onto SCC-CuMOF via ion exchange and coordination interaction. In general, SCC-CuMOF has the potential to remove Pb 2+ from wastewater rapidly and efficiently.
研究领域:
环境科学
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材料科学
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化学工程
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水处理
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2026
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IF 5.9
Hongyan Chen,Zhiying Shen,Dan Shen,Xiaowu Wang,Lugang Mei,Bo Yang
Novel PPCM hydrogel integrates mussel-inspired wet adhesion and CuMOF. • The composite shows robust tissue adhesion and sustained copper ion release. • Excellent antibacterial efficacy against MRSA and E. coli is achieved. • Hydrogel significantly accelerates infected wound closure and neovascularization. • The platform combines ECM-mimetic, antimicrobial, and pro-healing functions. Infected wounds pose a significant clinical challenge due to bacterial colonization, excessive inflammation, and impaired tissue regeneration. Inspired by the adhesive properties of mussel foot proteins, this study developed a novel multifunctional wound dressing by incorporating polydopamine (PDA)-modified copper-based metal-organic framework (CuMOF) into a polyethylene glycol (PEG) hydrogel network. The synthesized PEG/PDA@CuMOF (PPCM) hydrogel combines the extracellular matrix (ECM)-mimetic properties of PEG with the robust wet adhesion, antimicrobial, and pro-regenerative activities of CuMOF. Comprehensive characterization confirmed successful PDA coating on CuMOF and covalent integration into the hydrogel, which exhibited excellent porosity and swelling capacity. In vitro assessments demonstrated outstanding biocompatibility, significant promotion of cell proliferation and migration, and powerful antibacterial efficacy against both methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli ( E. coli ). In a rat model of full-thickness MRSA-infected wounds, the PPCM significantly accelerated wound closure, enhanced collagen deposition, promoted neovascularization, and effectively reduced bacterial burden, all while maintaining excellent systemic biocompatibility. These findings highlight the PPCM hydrogel as a promising multifunctional platform for advanced infected wound management.
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
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IF 8.2
Mohamed Bahri,Guoguang Rong,Xixi Song,Peiwu Qin,Mohamad Sawan
Signal amplification has become a paramount strategy in biosensing, offering substantial improvements in sensitivity and detection limits for analytical platforms. However, conventional methods often rely on separate amplification stages and intricate chemical functionalization, leading to inefficiencies and greater complexity in biosensing workflows. In this article, we introduce a novel dual-purpose application of AuNPs@CuMOF for both surface functionalization and signal amplification, enabling electrochemical biosensing of neuron-specific enolase (NSE), a key biological marker for neuronal disorders and small cell lung cancer. The proposed biosensing strategy implies immobilizing the biotinylated NSE antibody onto the AuNPs@CuMOF-functionalized surface of a screen-printed carbon electrode (SPCE), alongside a thiolated NSE aptamer conjugated to AuNPs@CuMOF for signal amplification. Following this approach, the proposed immunosensor showcased a detection limit (LOD) down to 0.02 pg/mL within the span of 0.1 pg/mL to 200 ng/mL, outperforming or matching previously reported NSE biosensors. Besides, the suggested NSE biosensor reliably identified NSE in spiked human serum samples, showing both strong selectivity and sensitivity, with performance metrics on par with those of standard ELISA tests, with the relative error ranging from 12.03% to 5.63%. By leveraging the combined advantages of CuMOF’s large surface area, versatility, and stability, the proposed method simplifies the biosensing workflow while enhancing sensitivity through intrinsic amplification, resulting in a robust and efficient platform for the detection of biomarkers. We highlight in this work the transformative potential of multifunctional nanomaterials in advancing electrochemical biosensing technologies, wihch represents a significant milestone in tumor diagnosis in clinical settings.
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产品关联
DOI
PubMed
高影响因子
TALANTA
·
2026
·
IF 6.7
Xinyi Wang,Minghao Wang,Wenbin Zhang,Dewang Yan,Liubing Kong,Gaofeng Wang
Accurate cortisol monitoring is essential for stress assessment and health management, yet reliable quantification remains challenging because signal fluctuations and matrix effects can compromise the performance of conventional single-mode immunosensors. Herein, we developed a fluorescence-colorimetric (FL-CL) dual-modal immunosensor based on a CuMOF-PEI@AuNPs@HRP (CPA) immunoreceptor for cortisol determination. The integrated sensing architecture generates correlated fluorescence and colorimetric responses from the same recognition event, which are combined through a normalized dual-signal output to improve calibration reliability. Under optimized conditions, the proposed sensor exhibited a detection limit of 0.22 ng/mL and a linear range of 3.1-200 ng/mL, covering physiologically relevant cortisol concentrations in saliva. Compared with single-modal assays and commercial kits, the proposed platform demonstrates enhanced sensitivity, improved correlation, good stability, and batch reproducibility. By integrating signal amplification, dual-modal readout, and simplified immunoreceptor fabrication within a single sensing platform, this work provides a reliable strategy for cortisol monitoring and offers potential for extension to other biomarker detection systems.
✓ 已验证
DOI
PubMed
高影响因子
Biomaterials Advances
·
2025
·
IF 6
Yixun Zhang,Wenjie Xie,Jinchuang Li,Zhenguo Liang,Xin Zhou,Zeheng Tan,Zhenjie Wu,Jundong Lin,Yangjia Zhuo,Fen Zou,Biyan Wen,Jianwei Chen,Shanghua Cai,Jianheng Ye,Yingke Liang,Jianming Lu,Huikang Yang,Weide Zhong,Ronghua Yang
Melanoma, a highly aggressive skin cancer, continues to challenge current therapeutic modalities due to its resistance and high mortality rates. Recent advancements highlight cuproptosis, a copper-driven form of programmed cell death, as a promising target for melanoma treatment. This study integrated machine learning and large-scale genomic data to identify FDX1 as a pivotal gene in cuproptosis-related pathways for melanoma. We developed a novel nanomedicine, ACM@MCHS-CuMOF@Dox, combining Mesoporous Carbon Hollow Spheres (MCHS) loaded with Copper-based Metal-Organic Frameworks (CuMOFs) and Doxorubicin (Dox), to exploit this discovery. The nanomedicine leverages a biomimetic approach by incorporating A375 cell membranes, enhancing tumor-targeted delivery. Physicochemical characterization confirms optimal drug loading and pH/GSH-responsive release profiles. In vitro studies demonstrate that ACM@MCHS-CuMOF@Dox inhibits melanoma cell proliferation, migration, and invasion, outperforming other formulations. Mechanistic investigations revealed that ACM@MCHS-CuMOF@Dox induced robust apoptosis and cuproptosis through FDX1 downregulation, thereby enhancing oxidative stress and therapeutic efficacy. These findings underscore the potential of combining machine learning-driven target identification with advanced nanomedicine for precision melanoma therapy. This approach offers a promising strategy for overcoming current treatment limitations and advancing personalized cancer care.
研究领域:
肿瘤学
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纳米医学
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生物信息学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2022
·
IF 6.76
Huizhi Wu,Qian Geng,Yonghan Li,Yuqian Song,Jiaqi Chu,Rong Zhou,Xin Ning,Senjie Dong,Ding Yuan
Here, a multifunctional poly (lactic acid)/copper-based metal–organic framework (PLA/CuMOF) degradable composite membrane featuring superior antibacterial and self-cleaning properties was fabricated via a simple electrospinning process for high- efficiency filtration/separation. Benefiting from the decrease of fiber diameter, the improved surface roughness and the surface charge of CuMOF, PLA/CuMOF fibrous membrane achieved excellent capture ability for ultra-fine particles and superb purification capability for real PM 2.5 smoke. The differences of filtration capacity between PLA membrane and PLA/CuMOF membrane was further explored using analogue simulation with dynamic particle capture and airflow field distribution. Impressively, PLA/CuMOF fibrous membrane combines robust self-cleaning ability, effective antibacterial effect, and thermal management capability. Moreover, owing to the special selective wettability and chemical stability, PLA/CuMOF membrane possessed the stable oil–water separation performance under harsh environment (e.g., high acid, alkali, and salt). This degradable multifunctional filtration/separation fibrous membrane emerges a broad application prospect ranging from environmental governance, industrial security to personal protection.
研究领域:
材料科学
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环境科学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 2
·1-11
·
IF 5.833
Wang Xiaoying,Li Linyu,Gu Xuan,Yu Bingjia,Jiang Meng
The aggregation of amyloid-β oligomers (AβOs) with extremely strong neurotoxicity has been proved to be the main pathogenesis of Alzheimer’s disease (AD). For sensitive quantification of AβOs, a switchable electrochemical aptasensor is proposed. Metal organic framework carrying Au nanoparticles (AuNPs@CuMOF) has been used to label signaling displaced-probe (SD), which formed triple helix switch (THS) by hybridizing with label-free anti-AβOs aptamer (Apt) on the electrodeposited palladium electrode (EPd). Thus, a relatively strong response of differential pulse voltammetry (DPV) was produced (switch on). With the specific binding between AβOs and Apt, the DPV response obviously decreased, owing to destroyed structure of THS and the separation of AuNPs@CuMOF/SD from the EPd (switch off). The mode of “switch on-off” can dramatically enhance the AβOs-dependent DPV intensity change. As a result, the switchable EA exhibited excellent selectivity and sensitivity with the linear range from 0.5 fM to 500 fM and the detection limit of 0.25 fM. When evaluating the AβOs of artificial cerebrospinal fluid (aCSF) samples, the switchable EA exhibited desirable feasibility, and the results are basically consistent with the enzyme linked immunosorbent assay (ELISA). The work could provide a potential tool of the AD diagnosis and a bright future in clinical applications.
研究领域:
分析化学
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生物传感器
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神经科学
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诊断学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）