INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Yuan Zhu,Tian-Xiao Yang,Ben-Kun Qi,Hang Li,Qing-Sheng Zhao,Bing Zhao
Deep eutectic solvents (DESs) have been extensively applied to pretreat lignocellulose; however, comparative research on acidic and alkaline DES pretreatment is relatively lacking. Herein, pretreatment of grapevine agricultural by-products with seven DESs were compared in terms of removal of lignin and hemicellulose and component analysis of the pretreated residues. Among the tested DESs, both acidic choline chloride-lactic (CHCl-LA), and alkaline potassium carbonate-ethylene glycol (K 2 CO 3 -EG) were effective in delignification . Thereafter, the CHCl-LA and K 2 CO 3 -EG extracted lignin was compared by analyzing their physicochemical structure changes and antioxidant properties. The results showed that the thermal stability , molecular weight, and phenol hydroxyl percentage of CHCl-LA lignin were inferior to K 2 CO 3 -EG lignin. It was found that the high antioxidant activity of K 2 CO 3 -EG lignin was mainly attributed to the abundant phenol hydroxyl, guaiacyl (G), and para-hydroxy-phenyl (H). By comparing acidic and alkaline DES pretreatments and their lignin nuances in biorefining, novel insights are derived for the scheduling and selection of DES for lignocellulosic pretreatment.
研究领域:
化学工程
·
生物技术
·
农业科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yongjie Zhou,Jiamin Liang,Yan Zhang,Huijuan Zhang,Sam K.C. Chang,Hui Hong,Yongkang Luo,Yuqing Tan
Deep eutectic solvents (DESs) are renowned in chemical and food industries for their eco-friendly extraction efficacy. Silver carp swim bladders, a collagen-rich byproduct of surimi production, are underutilized, resulting in considerable protein waste. Traditionally, collagen extraction has relied on harsh acids, contributing to environmental pollution and producing collagens with limited solubility, thus constraining their applications. This study evaluated DESs compared to conventional acids in extracting collagen, focusing on structural and solubility variations. Notably, urea-based DESs (urea-lactic acid: U-LA, 1:10, w/v) achieved the highest hydroxyproline recovery rates (∼ 94 %), comparable to acetic acid (AA, 1:20, w/v), but with half the solid-liquid ratio. Unlike acid-extracted collagen, which preserved the triple-helical structure, urea-based DESs partially disrupted this configuration by reducing intramolecular hydrogen bonding within collagen. However, these solvents simultaneously increased intermolecular hydrogen bonding. This alteration significantly enhanced collagen's solubility, maintaining over 60 % across a broad pH range (1−10) and various NaCl concentrations (0–6 %, w/v). Furthermore, urea-acetic acid (U-AA) extracted collagen exhibited the highest maximum transition temperature (solid state, T max = 101.94 °C) and gel strength (165 g). The findings suggest that urea-based DESs not only enhance collagen recovery rates but also its solubility and gelation properties, broadening its potential applications in cosmetics, food products, and biomaterials.
研究领域:
化学
·
食品科学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2025
·
IF 4.8
Li Wen,Meng Xiang-Guang,Yu Wen-Wang,Zhou Jie,Li Yan,Chu Dan-Dan
The dissolution of cellulose is an essential prerequisite for the development and utilization of cellulose. Here, a mixed solvent system containing deep eutectic solvents (DESs) and non-protonic organic solvents was prepared for the dissolution of three kinds of cellulose. This solvent system exhibited excellent ability for the dissolution of cellulose. The prepared mixed solvent system, comprising DESs synthesized from 1,1,3,3-tetramethylguanidine and acetic acid in combination with dimethyl sulfoxide and N , N -dimethylacetamide, could dissolve up to 29 wt% of microcrystalline cellulose, 24 wt% of bleached eucalyptus kraft pulp and 16 wt% of purified cotton with high polymerization degree at 80 °C. “Conjoining ion pairs” may be the main role in destroying the hydrogen bonds and promoting the dissolution of cellulose. The polymerization degree of the three regenerated celluloses only slightly decreased, and their infrared spectra did not show significant changes. This solvent system is inexpensive, easy to prepare, and recyclable.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Zihao Ma,Ying Han,Fuqiong Xu,Xing Wang
As a synthetic pigment, Sudan red is commonly used as a food additive and is harmful to the human kidney and can even cause cancer. In this work, we developed a one-step strategy to synthesize lignin-based hydrophobic deep eutectic solvents (LHDES), which were fabricated via methyltrioctylammonium chloride (TAC) as hydrogen bond acceptor and alkali lignin as hydrogen bond donor. LHDES with different mass ratios were synthesized and the mechanism of formation was determined by different characterization techniques. The synthetic LHDES was used as the extraction solvent to establish a vortex-assisted dispersion-liquid microextraction method for the determination of Sudan red dyes. The practicality of LHDES was evaluated by applying it to the detection of Sudan Red I in real water samples (seawater, river water) and duck blood in foodstuffs, and the obtained extraction rate reached up to 98.62 %. The method is simple and effective for the determination of Sudan Red in food.
研究领域:
环境科学
·
分析化学
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF CHEMICAL KINETICS
·
2024
·
IF 1.5
Jumei Xu,Ningrui Zhao,Zuoxiang Zeng,Weilan Xue
In this work, the optimum process conditions and kinetics of the green synthesis of isobutyl cinnamate using deep eutectic solvents (DESs) as catalysts were investigated. Isobutyl cinnamate is a spice with low toxicity and is widely used in the food industry. However, there is a lack of reports on its green synthesis. Three DESs were prepared by adjusting the mixing ratio of choline chloride (ChCl) and p-toluenesulfonic acid (PTSA). Response surface methodology with Box-Behnken design (RSM-BBD) was used to optimize the process parameters of the esterification of cinnamic acid with isobutanol. The effects of catalyst loading, stirring speed, cinnamic acid/isobutanol molar ratio, and temperature on the conversion of cinnamic acid over time were evaluated. Using ChCl-PTSA as a catalyst, the kinetics data and chemical equilibrium constants of the esterification were determined at a temperature range of 353.15–383.15 K. The pseudo-homogeneous (PH) model based on activity was then adopted to describe the kinetics of the reaction, and the relative deviations between the experimental values and the calculated ones by PH model are less than 5.5%. Thermodynamic data (Δ r H 0 , Δ r S 0 , Δ r G 0 ) for the esterification reaction was calculated as well. In addition, the results of six consecutive cycles of the catalyst showed that ChCl-PTSA has good stability and recyclability.
研究领域:
有机化学
·
催化化学
·
食品科学
✓ 已验证
DOI
高影响因子
SEPARATION SCIENCE AND TECHNOLOGY
·
2021
·
IF 2.475
Haoran Liu,Siyu Chen,Xiuping Li,Rongxiang Zhao,Yue Sun
A series of [EMIM]DEP/nC3H4O4 (n = 1, 2, 3) deep eutectic solvents (DESs) were synthesized by heating and stirring the mixture of 1-ethyl-3-methylimidazolium diethylphosphate ([EMIM]DEP) and propanedioic acid (C3H4O4). [EMIM]DEP/2C3H4O4 was characterized by Fourier transform infrared (FT-IR), 1H nuclear magnetic resonance (1H NMR), and thermogravimetric analysis (TGA). Dibenzothiophene (DBT) in model oil was removed using the DESs as an extractant and catalyst, and H2O2 as an oxidant. The influence parameters of different systems, temperature, n(H2O2)/n(S), dosage of [EMIM]DEP/2C3H4O4, and the sulfide type on desulfurization were investigated. The experimental results show that removal rate of DBT can attach to 98.2%. FT-IR analysis of DBT, DESs, and the mixture (DBT-DESs) show that there is an interaction between DBT and DESs.
研究领域:
化学工程
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
AICHE JOURNAL
·
2026
·
IF 4.4
Shaojie Ma,Bangzhu Wang,Weiming Zhai,Xinyu Liu,Linlin Chen,Yanhong Chao,Hongping Li,Huaming Li,Peiwen Wu,Wenshuai Zhu,Chunming Xu
Selective capture of structurally diverse molecules remains a major challenge in chemical separations. Here, we introduce dual-acidic deep eutectic solvents (DESs) in which Lewis acids modulate the Brønsted acidity, creating a synergistic environment for the simultaneous extraction of basic and non-basic nitrogen-containing molecules. Brønsted sites, activated by adjacent Lewis centers, preferentially bind basic heterocycles, while the Lewis sites coordinate with non-basic species, achieving unprecedented extraction efficiencies. Mechanistic studies combining FT-IR spectroscopy, density functional theory, and molecular electrostatic potential analysis reveal that proton transfer, Lewis acid–base coordination, and π–cation interactions collectively govern selective recognition. This dual-acidic design strategy is generalizable across different LA-metal DES compositions and robust against competing chemical species. Our findings demonstrate a rational approach to fine-tune cooperative acid functionalities, establishing a versatile platform for selective molecular capture and separations beyond conventional single-acid systems.
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2016
·Vol. 41
·期 1
·290-301
·
IF 3.277
Shokat Sarmad,Yujiao Xie,Jyri-Pekka Mikkola,Xiaoyan Ji
Deep eutectic solvents (DESs) as ionic liquid (IL) analogues show great potential for CO2 capture. They exhibit favorable solvent properties and are considered to be economical alternatives to conventional ILs. In this study, we prepare 35 DESs and screen them in terms of their CO2 solubility and viscosity, both crucial factors to be considered when designing efficient CO2 sorbents. The influence of salt and HBD type and structure, as well their molar ratio on the CO2 solubility and viscosity of the DESs is investigated. The viscosity and CO2 solubility of the DESs are compared with those of other DESs and conventional ILs. 15 DESs, which exhibit comparable CO2 absorption capacity to choline chloride–urea DESs, glycerol DESs and fluorinated ILs, are chosen as the promising ones. The viscosities of the selected DESs are below 200 mPa s and are lower than those of choline chloride-based DESs. Since the viscosity of the DESs is relatively high, on a par with those of conventional ILs, the effect of water as a co-solvent is investigated in order to decrease the viscosity. The addition of water to the glycerol-based DESs improves the kinetics of absorption by decreasing the viscosity, thus increasing the CO2 absorption capacity. Dry or aqueous DESs that demonstrate a high sorption capacity and low viscosity are chosen for additional analysis and characterization, and further functionalization will be carried out in the future to improve their sorption capacity.
研究领域:
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 21
·12805-12811
·
IF 3.108
Chunfeng Mao,Rongxiang Zhao,Xiuping Li,Xiaohan Gao
A series of deep eutectic solvents (DESs) of ChCl/XCF3SO3H (X from 1.0 to 2.0) were synthesized by stirring a mixture of choline chloride (ChCl) and trifluoromethanesulfonic acid (CF3SO3H) at room temperature. The DESs were characterized by Fourier transform infrared (FT-IR) and 1H nuclear magnetic resonance (1H NMR). The oxidative desulfurization of model oil was investigated using ChCl/1.5CF3SO3H as a catalyst and extraction agent, and H2O2 as the oxidant. Some reaction parameters such as type of DES, molar ratio of CF3SO3H and ChCl in DESs, H2O2 dose, reaction temperature, DES dose and type of sulfur compound were investigated. Under the optimum conditions, the removal rate of dibenzothiophene (DBT) and 4,6-dimethyldibenzothiophene (4,6-DMDBT) can reach up to 98.65% and 96.8%, respectively. After five recycling runs, the removal rate of DBT can still reach 97.16%.
研究领域:
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2026
·
IF 7.6
Haiyu Chen,Yanming Wang,Suen Hou,Shiwei Liu,Lu Li,Qiong Wu,Yue Liu,Yuxiang Liu,Weikun Jiang,Hailong Yu
The delignification mechanisms and structural evolution of lignin from poplar wood (PW) and corn stover (CS) were investigated during pretreatment with acidic, neutral, and alkaline choline chloride (ChCl)-based deep eutectic solvents (DESs). The delignification process was found to be primarily governed by the multi-level hydrogen bonding interactions. The hydrogen bond donors (HBDs) of DESs acted as “molecular crowbars” to preferentially disrupt the lignin hydrogen bonding network, while Cl– ions further extended the lignin conformation through stronger hydrogen bonding. Alkaline DESs formed the strongest hydrogen bonding interactions, achieving the highest delignification efficiencies (78.8% for PW; 89.3% for CS). They preferentially cleaved G-type β-O-4 bonds via a “deprotonation–cyclization–cleavage” mechanism, yielding high–molecular–weight lignin with excellent β-O-4 retention (∼50/100 Ar), abundant aliphatic hydroxyls, and low condensation degree. Acidic DESs, despite possessing the strongest individual hydrogen bond strengths, exhibited lower total interaction energies and delignification efficiencies (72.4% for PW; 71.3% for CS). They preferentially cleaved S-type β-O-4 bonds through a “protonation–elimination–cleavage” mechanism via benzyl carbocation intermediates, producing low–molecular–weight lignin with high phenolic hydroxyl content (∼3.5 mmol/g) but the highest condensation degree. Neutral DESs showed the lowest efficiencies (53.2% for PW; 64.2% for CS) due to weak hydrogen bonding interactions. Although following a similar cleavage mechanism to acidic DESs, their alcoholic HBDs readily captured carbocations to form α-etherification byproducts, hindering β-O-4 cleavage and yielding lignin with “intermediate-state” characteristics. This study provides theoretical guidance for targeted lignin depolymerization and high-value utilization.
✓ 已验证
DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2025
·
IF 6.2
Wenguang Li,Shubin Wu
The high-efficiency depolymerization of kraft lignin in DESs is very attractive and has potential applications. In the present study, we investigated the factors affecting lignin depolymerization in DESs and its product generation mechanism. The results indicated that the acidity of hydrogen bond donors (HBD) was positively correlated to the depolymerization of lignin. We synthesized a new binary DESs (Choline chloride (ChCl):4-chlorobenzene sulfonic acid (4-Cl-BSA)), and investigated the depolymerization of kraft lignin under different reaction conditions. Under the optimized conditions (150 ℃, 3 h, ChCl:4-Cl-BSA=1:0.7), the depolymerization rate of lignin reached 52.46 %. The yield of lignin oil reached 41.2 % with low molecular weight (M w ) and narrow polydispersity index (M w /M n ). Depolymerization experiment of lignin model compound, 2-phenoxy-1-phenylethanol (PPE) confirmed that condensation reaction occurred simultaneously with depolymerization reaction. Moreover, the lignin residue (RL) obtained was characterized by high hydroxyl content, narrow polydispersity index and high thermal stability. This is beneficial to the comprehensive utilization of RL. In the new binary DESs of ChCl:4-Cl-BSA, kraft lignin could be efficiently depolymerized into phenolic compounds. This study provides a new path for high-value utilization of kraft lignin.
研究领域:
生物化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2024
·
IF 5.3
Qihui Ding,Qian Shan,Qi Zhang,Mengda Chen,Ding Cai,Wei Wu
Hexagonal boron nitride (h-BN) with a large specific surface area and unique optoelectronic properties has good application prospects in many fields. The liquid phase exfoliation method is considered the most promising method for achieving controllable preparation of boron nitride nanosheets (BNNSs), but the low-cost, relatively environmentally friendly and efficient liquid phase exfoliation is still difficult to achieve. Choosing a suitable solvent system is the key to achieving efficient exfoliation. Deep eutectic solvents (DESs) have the advantages of simple synthesis, low cost, high thermal and chemical stability and strong biocompatibility and are expected to be green solvents for preparation of BNNSs . In this paper, it was found that the properties of DESs and its interaction with h-BN had a significant impact on the electrochemical exfoliation of h-BN. The intercalation effect of DES and the compatibility between DES and h-BN were the main factors affecting the yield, while the quality of BNNSs mainly depended on the decomposition and expansion effect of DES. This rule also can be applied to prepare highly conductive and hydrophilic two-dimensional material Ti-MXene. This research explores the structure–activity relationship between two-dimensional materials and DESs, and provides a theoretical basis for the environmentally friendly and efficient preparation of two-dimensional materials using DESs as exfoliation solvents.
研究领域:
材料科学
·
化学工程
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）