Electronics
·
2022
·Vol. 11
·期 19
·3254
·
IF 2.69
Ran Zhang,Qinyi Wang,Ya Chen,Chen Jiao,Fuxi Liu,Junwei Xu,Qiuwei Zhang,Jiantao Zhao,Lida Shen,Changjiang Wang
With the growing emphasis on medical testing, people are seeking more technologies to detect indexes of the human body quickly and at a low cost. The electrochemical biosensors became a research hotspot due to their excellent properties. In this study, dicopper hydroxide phosphate (Cu2(OH)PO4) was incorporated in resin, and the resin sheets were prepared by digital light processing (DLP). The copper base points were activated on the resin sheet surface by Nd: YAG laser and then covered by the electroless copper plating and the electroless silver plating. The laser could effectively activate copper base points on the resin surface. Furthermore, silver electrodes on the detection chips could distinguish glucose solutions of different concentrations well. Finally, a novel detection kit with a three-electrode chip was designed for rapid health testing at home or in medical institutions in the future.Keywords:biosensor;DLP;laser activation;electroless plating;glucose testing
研究领域:
医学检测
·
材料科学
✓ 已验证
DOI
高影响因子
Materials
·
2023
·Vol. 16
·期 21
·6984
·
IF 3.4
Jingjiang Qiu,Junfu Li,Zhongwei Guo,Yudong Zhang,Bangbang Nie,Guochen Qi,Xiang Zhang,Jiong Zhang,Ronghan Wei
Microfluidic chips have shown their potential for applications in fields such as chemistry and biology, and 3D printing is increasingly utilized as the fabrication method for microfluidic chips. To address key issues such as the long printing time for conventional 3D printing of a single chip and the demand for rapid response in individualized microfluidic chip customization, we have optimized the use of DLP (digital light processing) technology, which offers faster printing speeds due to its surface exposure method. In this study, we specifically focused on developing a fast-manufacturing process for directly printing microfluidic chips, addressing the high cost of traditional microfabrication processes and the lengthy production times associated with other 3D printing methods for microfluidic chips. Based on the designed three-dimensional chip model, we utilized a DLP-based printer to directly print two-dimensional and three-dimensional microfluidic chips with photosensitive resin. To overcome the challenge of clogging in printing microchannels, we proposed a printing method that combined an open-channel design with transparent adhesive tape sealing. This method enables the rapid printing of microfluidic chips with complex and intricate microstructures. This research provides a crucial foundation for the development of microfluidic chips in biomedical research.Keywords:3D printing;microfluidic chips;DLP;direct printing;open channel design
研究领域:
生物医学工程
·
化学
·
生物学
✓ 已验证
DOI
PubMed
高影响因子
PHOTOCHEMISTRY AND PHOTOBIOLOGY
·
2019
·Vol. 95
·期 5
·1219-1229
·
IF 2.338
Zhiquan Li,Chong Wang,Wanwan Qiu,Ren Liu
Designing digital light processing (DLP) 3D printable photosensitive resins with antibacterial properties is especially vital because of their potential applications in various biomedical fields. In this contribution, a thiol–ene–acrylate ternary system with reduced volume shrinkage and fast photopolymerization rate was chosen as the antibacterial 3D printing matrix resin. Two quaternary ammonium salt-type antibacterial agents (QAC and SH-QAC) with different molecular weight were designed and prepared, which can participate in the curing of matrix resin to achieve contact antibacterial effect. The effects of antibacterial agent content on the photopolymerization kinetics and on thermal and mechanical properties were discussed in detail. When the amount of added QAC is 4wt%, the antibacterial rate is almost 100% for Escherichia coli and Staphylococcus aureus , and when the amount of SH-QAC is 10wt%, the antibacterial rate against S. aureus is also essentially 100%. Both antibacterial photosensitive resins have been successfully applied in DLP technology to fabricate tooth model with high precision.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Li Wan,Xueqi Chen,Peng Hu,Lijie Wang,Guowen Xiong,Yuxin Gou,Fanrong Ai
Currently, ceramic dentures are mainly obtained by using computer-assisted cutting block of material to obtain the shape as the removing a model of patient's mouth. Followed by immersion coloring, porcelain stacking, and sintering to obtain dentures similar to a patients' tooth, this is a large-loss and complex process. In this study, 16 standard tooth samples were successfully reduced by adding Fe 2 O 3 , Pr 6 O 10 , Er 2 O 3 , and MnO 2 . After the colorful ceramic powder and photosensitive resin were configured into a slurry, a close to the sample tooth dentures was successfully prepared using digital light processing (DLP). The flexural strength and compressive strength of the ceramic specimens prepared by this method reached 821.01 ± 51.72 MPa and 2.67 GPa ± 0.22 MPa. To verify the biosafety of the prepared ceramics, we performed an in vitro biological evaluation of rat fibroblasts (L929). The resulting showed that the extracts of the prepared ceramic teeth had good biosafety, and the cells could also attach to the surface of the prepared ceramics. Hemolysis experiments confirmed good blood compatibility. Thus, our results show that DLP-printed standard tooth-colored ceramic dentures have good mechanical properties and biocompatibility, and can provide a solution to patients seeking quick access to aesthetic dentures.
研究领域:
材料科学
·
生物医学工程
·
口腔医学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Guoan Qi,Yong Zeng,Jimin Chen
Porous tin oxide-based (SnO 2 -based) ceramics with lattice structures were prepared by digital light processing (DLP) 3D printing technology. A 57 wt% SnO 2 -based DLP slurry was prepared by rheological experiments. By optimizing the exposure time, the DLP process for preparing SnO 2 based ceramics had better molding accuracy. The printing size error could be controlled at about 1.8%. The degreasing and sintering curves were obtained by thermogravimetric-differential scanning calorimetry (TG-DSC) analysis, and the SnO 2 -based porous ceramics with porosity of 50%–71% were prepared. The SnO 2 -based ceramics with high densification could be obtained by sintering at 1300 °C for 2 h. The relative density of printed SnO 2 -based ceramics was about 92%. In this paper, zinc oxide (ZnO) was selected as a sintering additive to promote the densification of SnO 2 ceramics. According to the characterization methods of scanning electron microscopy(SEM), X-ray diffraction(XRD), Energy dispersive spectrometer (EDS) and relative density, the optimum doping amount of ZnO was 9 wt%. The influence of pore structure on compressive strength was analyzed by finite element simulation and compressive test. The compressive strength of porous ceramics could be reduced from 1.56 MPa to 0.27 MPa by controlling the porosity of the porous lattice from 50% to 71%. The compressive strength of the solid block was 160 MPa. In this study, the porous SnO 2 -based ceramics prepared can be used in porous electrodes, lithium-ion batteries, supercapacitors , catalysts, sensors and other fields in the future.
研究领域:
材料科学
·
陶瓷工程
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Mengyuan Yu,Guifen Fan,Yingkang Li,Xile Ling,Feng Gong,Gang Liu,Jiaming Bai,Mantian Li,Peng Zhou,Dongyang Zhang,Lining Sun
Achieving the synergy of low viscosity, high printing precision and enhanced curing ability for lead zirconate titanate (PZT) components is a critical issue in the field of digital light processing (DLP). Herein, the effect of calcination temperature on the morphology and grain size of PSNZT [(Pb 0 . 92 Sr 0 . 08 )(Zr 0 . 533 Ti 0 . 443 Nb 0.024 )O 3 ]ceramic powder has been investigated, and a lowest viscosity, higher printing precision and enhanced curing ability of PSNZT ceramic slurry has been achieved, resulting in a high piezoelectric constant (d 33 = 379pC/N) and a high dielectric constant (εr = 1308@100 KHz) via DLP process combined with following sintering densification (1220 °C/3 h).
研究领域:
材料科学
·
电子工程
✓ 已验证
产品关联
DOI
高影响因子
Materials Today Communications
·
2025
·
IF 4.5
Da Bian,Junnai Wang,Jie Guo,Xinjian Cao,Shanhua Qian,Jun Yang,Weimin Liu
Digital light processing (DLP) has been widely utilized in ceramic additive manufacturing, while research on its application for fabricating metallic materials remains in the initial stages. In this paper, the geometric accuracy, mechanical and tribocorrosion properties of AISI 316 L prepared by DLP (DLP-316L) are systematically evaluated. DLP technology exhibits high forming accuracy in additive manufacturing of metal parts, with dimensional errors controllable within ± 70 μm and surface roughness of 1.6 μm. The microstructure of DLP-316L comprises austenite with minor δ-ferrite and M 23 C 6 /M 7 C 3 carbides. The carbides originate from residual carbon due to incomplete decomposition of photosensitive resin during debinding, while δ-ferrite forms during prolonged high-temperature sintering at 1380 °C for 6 h. It not only has a high ultimate tensile strength of 543.5 MPa, but more importantly, the fracture elongation can reach 58.73 %, which is at a high level in the preparation of AISI 316 L using DLP. In addition, the tribocorrosion performance of DLP-316L in 3.5 wt% NaCl solution is better than that of the commercial as-rolled AISI 316 L. This is mainly attributed to the presence of a small amount of high-hardness carbides in the microstructure, which improves the wear and corrosion resistance of the material.
研究领域:
材料科学
·
增材制造
·
表面工程
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Guoxuan Xu,Ketao Hu,Rui Zhou,Ruizhe Xing,Jie Kong
This work introduces a novel digital light processing (DLP) printable SiBCN(O) ceramic precursor (UV-hPBSZ), derived through a straightforward aminolysis approach. The unique hyperbranched molecular structure of UV-hPBSZ leads to remarkable UV curing efficiency, excellent printability, satisfied ceramic yield, and consistent shrinkage ratio. UV-hPBSZ also exhibits superior resistance against cracking and collapse during the polymer-to-ceramic process, thus enabling the fabrication of intricate SiBCN(O) ceramic structures. Upon pyrolysis at 1200 °C, the resulting SiBCN(O) ceramic demonstrates outstanding electromagnetic wave (EMW) absorption performance, achieving full coverage in the X band ( R L min = -36.68 dB). To showcase the design flexibility, a distinctive metastructure is proposed and successfully fabricated using DLP printing technique. This SiBCN(O) metastructure absorber enables impressive EMW absorption in the Ku band (94.6 % coverage), attributed to surface resonance effects and multiple internal reflections. Moreover, SiBCN(O) ceramics exhibit excellent high-temperature stability, with less than a 1.63 % total mass change from room temperature to 1400 °C. UV-hPBSZ offers a simple but versatile way to control dielectric properties, which opens up new possibilities for multifunctional integrated EMW absorbers suitable for both ambient and high-temperature conditions.
研究领域:
材料科学
·
陶瓷工程
·
电磁学
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Bioprinting
·
2023
·
IF 8.4
Jianpeng Gao,Hufei Wang,Ming Li,Zhongyang Liu,Junyao Cheng,Xiao Liu,Jianheng Liu,Xing Wang,Licheng Zhang
Intramembranous ossification (IMO) and endochondral ossification (ECO) are two pathways of bone regeneration. The regeneration of most bone, such as limb bone, trunk bone, and skull base bone, mainly occurs in the form of endochondral ossification, which has also become one of the effective ways for bone tissue engineering. In this work, we prepared a well-structured and biocompatible methacrylated gelatin/polymethacrylic acid (GelMA/PMAA) hydrogel by digital light processing (DLP) printing technology, which could effectively chelate iron ions and continuously activate the hypoxia-inducible factor-1 alpha (HIF-1α) signaling pathway to promote the process of endochondral ossification and angiogenesis. The incorporation of PMAA endowed the hydrogel with remarkable viscoelasticity and high efficacy in chelation of iron ions, giving rise to the activation of HIF-1α signaling pathway, improving chondrogenic differentiation in the early stage, and facilitating vascularization in the later stage and bone remodeling. Therefore, the findings have significant implications on DLP printing technology of endochondral osteogenesis induced by the iron-chelating property of biological scaffold, which will provide an effective way in the development of novel bone regeneration.
研究领域:
组织工程
·
生物材料
·
再生医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Applied Ceramic Technology
·
2019
·Vol. 17
·期 3
·844-853
·
IF 1.074
Xingbang Li,He Zhong,Jingxian Zhang,Yusen Duan,Jingjing Li,Dongliang Jiang
Zirconia ceramics have shown a wide applicable prospect in dental prosthetics because it possesses excellent mechanical performance and biocompatibility. The rheological behavior and curing properties of zirconia stereolithography slurry were studied, as well as the microstructure of the green, pyrolyzed, and sintered body. Variquat CC-42 NS was proved to be effective for zirconia powder dispersing in photocurable resin (SP-RC700). The curing characteristic of slurry showed that the depth of penetration tended to increase with the solid loading. Finally, the zirconia all-ceramic crowns were fabricated via DLP-based stereolithography printer. Results showed that the particles were evenly distributed in the cured resin matrix without obvious agglomeration, and the interlayered structure disappeared after binder burnout. The sample with a major crystalline phase of tetragonal zirconia and a porosity of 10(1)% were obtained after sintering at 1550°C.
研究领域:
口腔材料学
·
生物医学工程
·
陶瓷材料科学
·
增材制造
·
牙体修复学
✓ 已验证
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2021
·
IF 4.527
Sa Liu,Lina Mo,Gangyuan Bi,Shenggui Chen,Diwei Yan,Junzhong Yang,Yong-Guang Jia,Li Ren
Digital light processing (DLP) 3D printing has been utilized to fabricate controlled porous β-tricalcium phosphate (β-TCP) scaffolds, which promote cell adhesion and angiogenesis during bone regeneration. However, the current limitation of DLP 3D printing for the fabrication of β-TCP scaffold is how to prepare a low viscosity ceramic slurry and remove the toxicity of residual non-polymerized slurry. The present study has developed a low viscosity ceramic slurry system by mixing β-TCP with photosensitive acrylate resin, and the viscosity of slurry is about 3 Pa s and the solid content of β-TCP can be as high as 60 wt%. After optimizing the ratio of slurry, printing, degreasing and sintering processes, the maximum compressive strength of the DLP printed scaffolds reaches up to 9.89 MPa, while the porosity keeps ca. 40%. According to the proliferation of cells, it confirms the preserved biocompatibility of DLP-fabricated β-TCP scaffolds. These porous scaffolds made by DLP 3D printing technology is of great significance for bone regeneration, and will also help to expand the application of DLP technology in biomedical field.
研究领域:
生物材料学
·
组织工程学
·
医学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Guoan Qi,Haihua Yao,Yong Zeng,Jimin Chen
In this study, highly loaded tin oxide-based (SnO 2 -based) porous electrodes were prepared by digital light processing (DLP) 3D printing technology. Firstly, the SnO 2 light-cured slurry was prepared. The curing process and heat treatment process were analyzed and optimized. Then the best process parameters were obtained. Antimony oxide (Sb 2 O 3 ) was selected as the conductive agent to improve the electrical conductivity of the SnO 2 -based electrode. Through the characterization of resistivity, SEM and XRD , the optimum doping amount of conductive agent Sb 2 O 3 was determined to be 6 wt. %. Three kinds of porous electrodes with different shapes were prepared by DLP 3D printing, and the printing accuracy and mechanical properties were characterized. The results showed that the forming dimension error was about 1.7 % in the X and Y direction, 2.3 % in the Z direction. And the average compressive strength was 18.1 MPa, which effectively ensured the shape integrity and mechanical stability of the printed parts. Then the electrochemical properties of DLP 3D printed SnO 2 -based electrode and conventional coated electrode were tested and compared. The results showed that the 3D printed porous electrode showed lower charge transfer impedance and higher ion diffusion efficiency, and the maximum charge transfer impedance could be reduced to 1/25 of the traditional electrode; At the same time, it showed better cycle performance and rate performance, and the capacity retention of the 3D printed porous electrode could be improved by about 29.0 % compared with the traditional electrode. This work shows that high-performance high-load porous electrodes can be accurately prepared by DLP 3D printing, which provides a new strategy for the future development of high-load thick electrodes.
研究领域:
材料科学
·
能源技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）