WATER RESEARCH
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2022
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IF 13.4
Siqi Liu,Andrey M. Kuznetsov,Weiqing Han,Alexei N. Masliy,Gregory V. Korshin
Methylated arsenic species are ubiquitous in the environment and resistant to removal by conventional treatment technologies. This study addressed this challenge based on the examination of the removal of dimethylarsinic acid (DMA) in a system that combines zerovalent iron (ZVI) and powdered activated carbon (PAC). The removal of DMA in the ZVI/PAC system was compared to that by coagulation, adsorption, electrochemical and Fenton oxidations, and other conventional methods. While only the electrochemical oxidation using a PbO 2 /Sb-SnO 2 /Ti anode allowed removing up to 60% DMA at several hours-long treatment times, the removal of DMA in the ZVI/PAC system containing 10 g/L ZVI and 2.5 g/L PAC with an initial pH of 2.0 was 95% for a 30 min reaction time. Specific roles of PAC, ZVI and its oxidation products in DMA removal were examined based on the spectroscopic data and quantum chemical modeling for the DMA/Fe(II) and DMA/Fe(III) systems. These methods demonstrated the formation of moderately strong DMA/Fe(II) and DMA/Fe(III) complexation. These results and relevant kinetic data were interpreted to indicate that the removal of DMA is governed by the rapid generation of Fe 2+ ions released as a result of accelerated ZVI corrosion in the galvanic ZVI/PAC microcells and ensuing formation of DMA/ Fe 2+ complexes that are readily adsorbed by PAC.
研究领域:
环境科学
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化学工程
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水处理
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PubMed
高影响因子
Materials
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2022
·Vol. 15
·期 15
·5351
·
IF 3.748
Jinyi Wu,Quantao Liu,Shaopeng Wu
Cracks are inevitable during the service life of asphalt pavement and the water at the fracture surfaces tends to cause the grouting materials to fail. Studies have shown that the catechol groups in adhesion proteins secreted by mussels can produce strong adhesion performance in the water. In this paper, the mussel-like adhesive L-Dopa Methacrylic anhydride (L-DMA) was prepared based on the concept of bionic design and used to improve the properties of asphalt. By using Fourier-transform infrared spectroscopy (FTIR) and Thermogravimetric analysis (TGA), the thermal stability and structural composition of L-DMA were investigated. Then, the rheological and low-temperature properties of L-DMA-modified asphalt were investigated using the dynamic shear rheological (DSR) test and bending beam rheological (BBR) test. Moreover, the modification mechanism was explored by FTIR. It was found that L-DMA can be effectively synthesized and has good thermal stability. The incorporation of L-DMA increases the composite modulus, viscosity, creep recovery rate and rutting factor of asphalt binder, resulting in an enhancement of its high-temperature performance. At a high L-DMA content of 10%, the low-temperature performance of the modified asphalt was enhanced. The modification of L-DMA to asphalt is mainly a physical process. Hydrogen bonds and conjugated systems generated by the introduction of catechol groups enhance the adhesion properties of asphalt. In general, L-DMA improves the properties of asphalt and theoretically can improve the water resistance of asphalt, which will be explored in future research.Keywords:L-DMA;mussel bionic materials;modified asphalt;modification mechanism;rheological properties
研究领域:
材料科学
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道路工程
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化学工程
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PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2024
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IF 8.2
Guohui Wang,Qixin Zhang,Lailai Qin,Kaixuan Tan,Chunguang Li,Lianshun Li,Tinggui Yang,Xiaojuan Liu
A novel metal-organic framework (MOF) material, MIL-100(Fe)-DMA, was synthesized using the solvothermal method. The structure of the MOF was characterized using scanning electron microscopy-energy dispersive X-ray spectroscopy, N 2 adsorption–desorption isotherms, X-ray diffraction analysis, Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy, and Mössbauer spectroscopy. Batch adsorption experiments were performed to investigate the effects of initial Sr 2+ and Cs + concentrations, adsorption time, pH, and coexisting cations on the adsorption performance of the material. The adsorption mechanism was further elucidated using adsorption kinetics and isotherm models. The results indicated that the adsorption of Sr 2+ and Cs + does not significantly affect the MOF material structure. As reaction time and initial ion concentration increased, the adsorption capacity of MIL-100(Fe)-DMA for Sr 2+ and Cs + increased rapidly and then gradually reached equilibrium. Optimal adsorption occurred under alkaline conditions, with maximum adsorption capacity observed at pH = 8. The adsorption process for Sr 2+ and Cs + was well described by the pseudo-second-order kinetic model, the Weber–Morris model, and the Langmuir adsorption isothermal model. The adsorption process was mainly identified as monolayer chemical adsorption, influenced by multiple factors. Characterization combined with density functional theory calculations revealed that the unsaturated carboxylic acid groups on the surface of the MOFs play a crucial role in the interaction with Sr 2+ and Cs + .
研究领域:
材料科学
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环境科学
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PubMed
高影响因子
OPTICAL MATERIALS
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2025
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IF 4.2
Zhenbeina Deng,Yusheng Xu,Ruijing Yang,Dacheng Zhou,Qi Wang,Jianbei Qiu
Developing efficient lead-free organic-inorganic hybrid metal halides (OIHMHs) remains a significant challenge due to inherent structural limitations. This study reports the synthesis of Sb 3+ -doped zero-dimensional (DMA) 4 InCl 7 single crystals (>0.5 cm) via a solvent-antisolvent method, notably without the use of DMACl precursors. Sb 3+ doping induces local lattice distortion, reducing the bandgap from 3.59 eV to 3.28 eV and resulting in intense orange self-trapped exciton (STE) emission at 560 nm, with a high photoluminescence quantum yield (PLQY) of 54.76 %. Density functional theory (DFT) calculations reveal that Sb 3+ -induced impurity states enhance electron-phonon decoupling and facilitate radiative recombination. A concept-validation device fabricated by directly coupling the crystal to a UV-LED chip produces stable yellow emission (CIE: 0.38, 0.51), highlighting its potential for practical optoelectronic applications.
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高影响因子
JOURNAL OF DENTISTRY
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2025
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IF 5.5
Huimin Wang,Wei Wei,Qi Lin,Zilu Tian,Shuwei Qiao,Tingting Bai,Xi He,Song Zhu
Objectives The effects of different interface treatments on the interfacial bonding of inorganic fillers in composite resins and the overall performance of the composite resins were investigated. Methods Synthetic mussel derivatives (N-3,4-dihydroxyphenethyl methacrylamide, DMA) were used as primers to treat the inorganic filler bonding interfaces, and the effects of different concentrations of DMA on the shear strength of the bonding interface were tested. Silica nanoparticles were coated on the surface of the filler via the sol-gel growing, and the mechanical properties and aging resistance of the composite resin were tested. Results The DMA primer concentration of 0.1–1mg/mL substantially improved the shear strength of the bonding interface, and combined with the coating of silica nanoparticles, it improved the compressive strength and toughness of the aged composite resin. Conclusions This study indicated that the use of the DMA primer and coated silica nanoparticles increased the bonding strengths and stabilities at the organic-inorganic interfaces, and also improved the mechanical strengths and durability of the composite resins. Clinical significance Fortified with DMA and silica nanoparticles, the composite resin exhibits great bonding strength, hydrolysis resistance, and toughness. This innovation could stabilize the resin for long-term and lower the risk of secondary caries. This study paves the way for the clinical application of novel resins to prevent secondary caries in the future.
研究领域:
材料科学
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牙科医学
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生物医学工程
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PubMed
高影响因子
MATERIALS LETTERS
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2026
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IF 2.6
Yuanbin Qin,Xin Yang,Pengcheng Zhang,Xiaohua Cheng,Qinqin Fu,Chuanwei Fan
A micropillar compression–nanoDMA method is developed for microscale T g measurement. • Flat-ended indenter averages local stiffness variations in filled polymers. • Smooth modulus and tan delta curves enable unambiguous T g identification. • T g is reliably determined from storage modulus onset, loss modulus peak, and tan delta peak. • The method applies to heterogeneous polymers in microelectronics and composites. The glass transition temperature (T g ) is a critical parameter for evaluating the thermal and mechanical stability of amorphous polymers, but accurate measurement for heterogeneous filled polymers at the microscale remains challenging. In this work, we present an accurate DMA method for determining the T g of filled polymers at the microscale via micropillar compression. Micropillars of a home-made silica-filled epoxy resin were fabricated by focused ion beam (FIB) and tested using a flat-ended diamond indenter on a nanoDMA instrument equipped with a high-temperature stage. The new method yields markedly smoother storage modulus, loss modulus, and tan delta curves, with greatly reduced point-to-point scatter, enabling clear identification of T g from the onset of storage modulus drop, the loss modulus peak, and the tan delta peak. In contrast, the conventional nanoDMA method exhibits substantial data scatter that obscures the glass transition.
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高影响因子
LANGMUIR
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2024
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IF 3.7
Yiran Jia,Yinuo Yang,Hongyu Zhang
Surface modification of lubricating coatings on biomedical devices is a pivotal strategy to improve the overall performance and clinical efficacy, significantly reducing friction between devices and human tissues and mitigating tissue damage during intervention and long-term implantation. Recently, various hydrophilic polymeric materials have been used for achieving surface functionalization, endowing the biomedical device with excellent superlubrication performance. N-Vinylpyrrolidone (NVP) and 2-methacryloyloxyethyl phosphorylcholine (MPC) are two typical representatives of nonionic and zwitterionic materials. However, there is still a research gap in a comparative study of the lubrication mechanisms and properties between them. In this study, a bioinspired and dopamine-assisted codeposition technique was used to fabricate biomimetic hydrophilic coatings, including P(DMA-NVP) and P(DMA-MPC), on polyurethane. To achieve a thorough comparative analysis of the self-adhesive coating performance, 3 M ratios of the copolymers were synthesized and comprehensive material evaluations were conducted. Additionally, surface morphology, hydrophilicity, and lubrication at both the microscale and macroscale were performed. It was found that both hydrophilic coatings exhibited good stability. The P(DMA-MPC) coating, due to the ability to attract and bind a large number of water molecules, demonstrated superior lubrication effects compared to the P(DMA-NVP) coating. The study provides an in-depth understanding of the lubrication behavior of the self-adhesive coatings to enhance the functionality and application in biomedical engineering.
研究领域:
生物医学工程
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材料科学
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表面化学
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2013
·Vol. 130
·期 1
·645-653
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IF 1.395
Wenlong Qin,Gang Wu,Peipei Yin,Hongzheng Chen
RGB tricolor organic pigments were in situ modified by stearyl methacrylate-2-(dimethylamino)ethyl methacrylate-styrene random copolymer [P(SMA-DMA-St)] through solution polymerization. The modified particles were charged in tetrachloroethylene (TCE) with the aid of suitable charge control agent. The structure and electrophoretic property of ink particles were characterized by FTIR, TEM, PALS, et al. P(SMA-DMA-St) modification decreased the particles size and enhanced the suspending stability of the pigments in tetrachloroethylene due to the repulsive forces among the treated pigment particles resulting from the extending polyacrylate chain in the media. Partial crosslinking the P(SMA-DMA-St) on the pigment surface with ethylene glycol dimethacrylate (EGDMA) helped to increase the Zeta potential and electrophoresis mobility of RGB electrophoretic particles. The maximum values of the Zeta potential for red, green, and blue electrophoretic particles reached −36.2, −57.7, and −42.7 mV, respectively. The obtained RGB electrophoretic particles could be applied in the color/white dual-particle electronic ink together with charged TiO 2 to show vivid color and white images under a DC electric field. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
研究领域:
材料科学
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高分子化学
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DOI
高影响因子
GREEN CHEMISTRY
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2026
·Vol. 28
·期 17
·7449-7458
·
IF 10.6
Siyu Pan,Demeng Liu,Delong Hou,Qi Zeng,Jun Yan,Yi Chen
DLin-MC3-DMA, the first FDA-approved ionizable lipid and a key component of lipid nanoparticles (LNPs), has enabled the clinical translation of RNA therapeutics. However, large-scale synthesis of DLin-MC3-DMA is limited by the challenging preparation of a symmetric secondary alcohol bearing two C18:2 alkyl chains, which typically requires multi-step procedures, stringent inert conditions and hazardous reagents, and affords only moderate yields. Here we report a tandem, mild synthesis strategy that converts methyl linoleate into a symmetric secondary alcohol bearing two C17:2 chains in 89% yield within 12 h. Subsequent esterification affords CLin-17, a structural analogue of DLin-MC3-DMA. LNPs formulated with CLin-17 exhibit high RNA encapsulation efficiency, a favorable pKa, and transfection efficiencies comparable to those of DLin-MC3-DMA-based LNPs across multiple cell lines, while maintaining low cytotoxicity and excellent storage stability. This work provides a facile approach to produce symmetric secondary alcohols for ionizable lipid synthesis, facilitating broader and more sustainable access to high-performance RNA delivery materials.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2015
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IF 5.056
Yue Cui,Zhi-Kan Yao,Ke Zheng,Shi-Yuan Du,Bao-Ku Zhu,Li-Ping Zhu,Chun-Hui Du
To explore low-pressure-driven nanofiltration (LPDNF) membranes with high permeate flux , a novel preparation route was proposed and investigated. First, an amphiphilic copolymer of poly (methyl methacrylate- co -dimethylaminoethyl methacrylate) (P(MMA- co -DMA)) was synthesized via free-radical copolymerization , and then blended with polyvinyl chloride (PVC) to fabricate precursor membranes via non-solvent induced phase separation (NIPS) process. Utilizing the quaternization and cross-linking reaction between p -xylylene dichloride (XDC) and tertiary amine units in PVC/PMMA- co -DMA precursor membranes, positively charged PVC/PMMA- co -DMA LPDNF membranes were obtained. Element alanalysis, X-ray photoelectron spectroscopy and scanning electron microscopy were employed to characterize the composition and morphology of the membranes. Effects of PMMA- co -DMA content and XDC concentration on the LPDNF membranes’ performance were studied and discussed. With the optimized condition, the NF membrane showed the highest salt rejection ( R ) and water flux ( J ), e.g., R MgCl 2 =89.1%, J MgCl 2 =22.1 L/(m 2 h) and R NaCl =45.1%, J NaCl =27.6 L/(m 2 h) at a pressure of 0.3 MPa. Besides, the rejections of the LPDNF membranes for inorganic salts increased in an order of Na 2 SO 4
研究领域:
材料科学
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膜技术
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环境工程
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高分子化学
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水处理
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DOI
高影响因子
MOLECULAR PHARMACEUTICS
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2025
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IF 4.5
Siyu Dong,Zhaoqi Pan,Mengchun Chang,Juanjuan Zhou,Mengke Zhang,Yashuang Chen,Ting Li,Ziwen Chen,Yuwan Gao,Sitao Xie,Wencan Wu,Xiangsheng Liu
Ionizable lipid serves as the key functional component in lipid nanoparticles (LNPs) for efficient mRNA delivery. This study aims to systematically evaluate clinically approved ionizable lipid DLin-MC3-DMA and SM102-based LNPs for ocular mRNA delivery, with a comprehensive assessment of their physicochemical characteristics, delivery efficiency, and biodistribution patterns within the ocular microenvironment. Enhanced green fluorescence protein or Luc encoding mRNA-loaded LNPs were formulated using microfluidic mixing technology and characterized by dynamic light scattering, ζ-potential measurements, and cryogenic transmission electron microscopy imaging. The two LNP systems with different ionizable cationic lipids demonstrated distinct capabilities for in vitro mRNA transfection and intraocular mRNA delivery following intravitreal administration. Notably, the SM102-LNPs exhibited superior performance compared to the MC3-LNPs, characterized by significantly higher transfection efficiency in retinal cells in vitro, and more efficient ocular expression with minimal systemic distribution in vivo. Safety assessment demonstrated that intravitreal administration of SM102-LNPs maintained excellent long-term biocompatibility throughout a five-month study period. The superior performance of SM102-LNPs establishes a promising platform for ocular mRNA therapeutics.
研究领域:
药理学
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分子生物学
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眼科
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PubMed
高影响因子
DENTAL MATERIALS
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2022
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IF 5.687
Kang Li,Fung Man Ngo,Angela Yat Laam Yau,Winnie Wai Ling Tam,Edmund Chun Ming Tse,James Kit Hon Tsoi,Cynthia Kar Yung Yiu
Objectives To evaluate the inhibitory effect of a novel mussel-inspired monomer ( N -(3,4-dihydroxyphenethyl)methacrylamide (DMA) on the soluble and matrix-bound proteases . Methods The inhibitory effect of DMA (0, 1, 5, and 10 mM) and 1 mM chlorhexidine (CHX) dissolved in 50% ethanol/water on soluble recombinant human matrix metalloproteinases (rhMMP-2, −8, and −9), as well as cysteine cathepsins (B and K) were evaluated using both fluorometric assay kits and molecular docking . The effect of CHX and DMA on matrix-bound proteases was examined by in situ zymography , and the fluorescence intensity and relative area were calculated by Image J software. All data obtained were analyzed by one-way ANOVA followed by Tukey test (α = 0.05). Results The anti-proteolytic ability of DMA increased in a dose-dependent manner except that of rhMMP-9. Inhibitory effect of 1 mM DMA against rhMMP-2, − 8, − 9, as well as cathepsin B and K was all significantly lower than 1 mM CHX ( p < 0.05). The molecular docking analysis was in good agreement with the experimental results, that the binding energy of DMA was lower than CHX for all proteases. In situ zymography revealed that all DMA- and CHX-treated groups significantly inactivated the matrix-bound proteases, with a dramatic reduction of the fluorescence intensity and relative area compared with the control group ( p < 0.05). Significance Under the prerequisite condition that the overall inhibitory performance on matrix-bound proteases was comparable by DMA and CHX, the more selective property of DMA could avoid inducing potential negative effects by suppressing MMP-9 when applied in dental treatment compared with CHX.
研究领域:
口腔医学
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生物化学
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分子生物学
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PubMed
高影响因子
危险品化学品经营许可证（带存储）