JOURNAL OF MOLECULAR LIQUIDS
·
2022
·
IF 6.633
Yanjun Huang,Qingdi Kong,Xiaojie Zhang,Hong Peng
It is a challenging task to remove Pb(II) ions efficiently from wastewater containing high concentrations of hardness ions. In this study, a novel hybrid polymer (DVP) for selective adsorption of Pb(II) ions was successfully prepared via photopolymerization of vinyl-POSS and dimercaptosuccinic acid (DMSA). The chemical structure and composition of DVP were characterized by FTIR, XPS, SEM, TEM, XRD and TGA techniques. DVP exhibited high efficiency in removing Pb(II) from aqueous solutions with a maximum adsorption capacity of 349.5 mg g −1 at pH 4, exceeding lots of adsorbents reported in the literature. The adsorption performance of Pb(II) by DVP was found to fit the Freundlich isotherm well and its kinetics followed the Elovich model. Moreover, DVP showed selective adsorption of Pb(II) in the presence of high concentrations of Ca(II) and Mg(II) ions and could reduce Pb(II) in real lake water to 25 ppb at a DVP dose of 1 g L −1 . Moreover, the adsorption process of DVP was endothermic in nature. The adsorption mechanism demonstrated that Pb(II) ions can be chelated with the thioether and carboxyl groups of DVP simultaneously, which was confirmed by spectroscopic analysis and DFT calculations. Good reusability in continuous fixed-bed column experiments suggested that DVP was an ideal candidate for the selective removal of Pb(II) ions from contaminated aquatic systems.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2025
·
IF 5.1
Lin Yang,Xueling Liu,Bingyue Song,Sixian Yang,Xiaojie Zhang,Chong Zhao,Yixiao Wu,Lei Zhang,Yanjun Huang
Effective and selective recovery of precious metal silver (Ag(I)) from wastewater can promote resource recycling and mitigate environmental pollution. In this study, dimercaptosuccinic acid (DMSA) functionalized polyhedral oligomeric silsesquioxane (POSS)-based hybrid polymer (DPHP) was synthesized and employed for the adsorption of Ag(I) from aqueous solution. The obtained adsorbent was characterized using SEM-EDS, XPS, solid-state 13 C NMR, and 29 Si NMR spectra. Batch adsorption experiments were conducted to evaluate the adsorption performance of DPHP for Ag(I). The results revealed that the maximum adsorption capacity of DPHP for Ag(I) was 494.65 mg g −1 at pH 4, and the adsorption process could be well described by pseudo-second-order and Sips models. Thermodynamic studies implied the adsorption of Ag(I) was an endothermic and spontaneous adsorption process in nature. Adsorption and desorption experiments demonstrated that the regeneration efficiency of DPHP remained above 83 % after five cycles and the preconcentration factor of DPHP was determined to be 125. Furthermore, DPHP exhibited selectivity to Ag(I) in solutions containing a variety of competitive metal ions and simulated industrial wastewater. Based on density functional theory (DFT) calculations, as well as XPS, FTIR, and Raman analyses, the interaction between Ag(I) and DPHP involved electrostatic attraction, ion exchange, and coordination, with the coordination mainly between thioether and carboxy groups and Ag(I) ions. Overall, DPHP is a promising adsorbent for the recovery of Ag(I) from aqueous solutions.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Zhuqing Wang,Shasha Wu,Yuenan Zhang,Lijing Miao,Yujie Zhang,Aiguo Wu
A low-cost, environment-friendly sodium alginate-meso-2,3-dimercaptosuccinic acid hybrid aerogel (SA-DMSA) was synthesized by simple chemical grafting and vacuum freeze-drying method and used to remove heavy metal ions in wastewater. The as-prepared SA-DMSA showed high affinity for heavy metal ions, such as Pb 2+ , Cd 2+ , Cu 2+ , Cr 3+ , and Co 2+ , and can remove >90% of the metal ions from the corresponding solution. SA-DMSA also exhibited high selectivity to Pb 2+ and Cd 2+ , and the maximum adsorption capacities for Pb 2+ and Cd 2+ reached 116.4 and 91.2 mg/g, respectively. The SA-DMSA adsorbent can be regenerated by a simple one-step acid washing, and the adsorption performance remained stable after repeated use. Given its low-cost and easy-to-obtain raw materials, simple preparation process, and simple regeneration process of the adsorbent, SA-DMSA has broad application prospects in the treatment of low-concentration heavy metal ions, especially for wastewater containing Pb 2+ and Cd 2+ .
研究领域:
环境科学
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材料科学
✓ 已验证
DOI
高影响因子
TALANTA
·
2018
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IF 4.244
Guobin Mao,Chen Liu,Mingyuan Du,Yuwei Zhang,Xinghu Ji,Zhike He
Galactose oxidase is a copper-activated enzyme and have a vital role in metabolism of galactose. Much of the work is focused on determining the amount of galactose in the blood rather than measuring the amount of galactose oxidase to urge the galactosemia patients to restrict milk intake. Here, a simple and effective method was developed for Cu 2+ and copper-activated enzyme detection based on homogenous alloyed CdZnTeS quantum dots (QDs). Meso − 2,3-dimercaptosuccinic acid (DMSA) was used as the reducing agent for preparing QDs and the highest quantum yield of CdZnTeS QDs was 69.4%. In addition, the as-prepared CdZnTeS QDs show superior fluorescence properties, such as good photo-/chemical stability. The DMSA was the surface ligand of the QDs, containing abundant -SH and -COOH, thus the surface ligands have a high affinity with Cu 2+ . Therefore, this developed probe can be applied for Cu 2+ and galactose oxidase detection and shows a good sensitivity in the buffer. Then, this probe was successfully used for Cu 2+ and galactose oxidase detection in real samples with the satisfactory results. The proposed fluorescence quenching strategy gives a new and simple insight for enzyme assay without the enzyme-catalyzed reaction.
研究领域:
生物化学
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医学检测
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纳米技术
✓ 已验证
DOI
高影响因子
Journal of Central South University
·
2018
·Vol. 25
·期 4
·709-718
·
IF 0.761
Tian Qing-hua,Wang Xiao-yang,Mao Fang-fang,Guo Xue-yi
The purpose of this study is to explore the adsorption performance of meso-2, 3-dimercaptosuccinic acid (DMSA) modified Fe3O4@SiO2 magnetic nanocomposite (Fe 3 O 4 @SiO 2 DMSA) for Pb 2+ ions removal from aqueous solutions. The effects of solution pH, initial concentration of Pb2+ions, contact time, and temperature on the amount of Pb2+ adsorbed were investigated. Adsorption isotherms, adsorption kinetics, and thermodynamic analysis were also studied. The results showed that the maximum adsorption capacity of the Fe 3 O 4 @SiO 2 DMSA composite is 50.5 mg/g at 298 K, which is higher than that of Fe3O4 and Fe 3 O 4 @SiO 2 magnetic nanoparticles. The adsorption process agreed well with Langmuir adsorption isotherm models and pseudo second-order kinetics. The thermodynamic analysis revealed that the adsorption was spontaneous, endothermic and energetically driven in nature.
研究领域:
环境科学
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材料科学
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纳米技术
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水处理
✓ 已验证
DOI
高影响因子
FOOD CONTROL
·
2025
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IF 6.3
Xiaoyong Hu,Yuhuan Qin,Jiahui Zhao,Joseph Brake,Shuangbo Zhang,Wenxue Sun,Jiang Bian,Xiaobin Wu
The extensive use of chromium in various industrial processes may cause toxic effects in organisms due to its accumulation in the environment and foods. Traditional methods for chromium detection are time-consuming and infeasible for on-site usage. It is urgent to build a rapid, real-time and economical method for determining chromium to ensure human health and environmental safety. Here we developed an optimized colorimetric method for rapid detection of Cr 3+ ion based on the specific chromium chelator 2′3-dimercaptosuccinic acid (DMSA) which was screened by a novel biological method. Chemical methods further verified the specificity of DMSA for chromium. Both in vitro and in vivo experiments demonstrated that DMSA is safe for utilization. DMSA was complexed with gold nanoparticles (AuNPs) to increase the specificity and sensitivity for Cr 3+ . The optimized DMSA-AuNPs reaction achieved a color change from wine red to blue upon adding Cr 3+ at less than 5 μM. The naked-eye visual detection limit was 0.5 μM with a total reaction time of less than 1 min. The linear range of this colorimetric sensor was 0.5–5 μM and the detection limit reached 23 nM. The Cr 3+ detection by DMSA-AuNPs across several food samples including rice, soybean, milk, grape, peach and cabbage was consistent with those determined by inductively coupled plasma-mass spectrometry. Its detection results in 6 food samples (rice, soybean, milk, etc.) are highly consistent with ICP-MS (correlation coefficient R 2 > 0.99), and the entire detection process can be completed within 1 min. Our study provides an original and practical method for rapid, safe, on-site and cost-effective chromium monitoring of water, foods and the environment.
研究领域:
环境科学
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食品安全
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纳米技术
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分析化学
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毒理学
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 16
·7862-7872
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IF 3.3
Zhuhui Chen,Yue Xiong,Ranran Ma,Pei Chen,Le Duan,Shuying Yang,Ineza Urujeni Gisèle,Linjun You,Deli Xiao
To overcome the low concentration and matrix complexity of N1-methylnicotinamide (MeNam) in biological samples, this work developed a method for the detection of MeNam in urine samples using a Fe3O4@hydroxypropylmethylcellulose@2,3-dimercaptosuccinic acid (Fe3O4@HPMC@DMSA) magnetic fluid as a pre-treatment material in combination with high performance liquid chromatography. The novel adsorbent material exhibited ultra-fast adsorption kinetics and a large adsorption capacity because Fe3O4@HPMC@DMSA NPs acted as a homogeneous magnetic fluid with more varieties and quantities of interaction sites (hydrogen-bonding interaction and electrostatic interaction). The limit of determination for MeNam was 0.05 μg mL−1 with Fe3O4@HPMC@DMSA NPs. Recoveries of spiked urine samples ranged between 95.49% and 106.4%, indicating that the developed method was promising for the accurate quantification of trace amounts of MeNam in urine samples. It provides research value for the rapid assessment of the nutritional effects of NMN dietary supplements and offers a sensitive assay for metabolism studies of related functional foods.
研究领域:
分析化学
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生物医学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
·
IF 5.4
Yunxiang Du,Zhuoyue Lan,Hang Li,Zhiyu Pu,Letian Hu
This study presents the application of dimercaptosuccinic acid (DMSA) as a selective depressant for chalcopyrite in copper-molybdenum separation, with a systematic investigation of its mechanisms of action. Single-mineral flotation tests showed that under weakly alkaline conditions, DMSA demonstrated significant depressant effects on chalcopyrite, while having a minimal impact on the recovery of molybdenite. In artificial mixed ore tests at a DMSA dosage of 40 mg/L, the molybdenite concentrate achieved a grade of 59.86 % with a recovery of 83.04 %, while the chalcopyrite concentrate achieved a grade of 0.49 % and a recovery of only 1.18 %. Using multi-scale characterization techniques, including contact angle measurement, SEM-EDS, zeta potential analysis, LEIS, FTIR, and XPS, it was found that DMSA interacts with metal sites on the chalcopyrite surface via its -SH groups, forming a hydrophilic chelating complex. This complex prevents the adsorption of kerosene effectively. Molecular dynamics simulations further validated that DMSA enhances the density of water molecules on the chalcopyrite surface. DMSA therefore selectively depresses the flotation of chalcopyrite, enabling the efficient separation of chalcopyrite and molybdenite.
研究领域:
矿物加工
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冶金学
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表面化学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Nanotoxicology
·
2023
·
IF 5
Xue Zhang,Fei Kong,Tian Wang,Xin Huang,Wanqing Li,Meichen Zhang,Tao Wen,Jian Liu,Yu Zhang,Jie Meng,Haiyan Xu
Iron oxide nanoparticles (IONPs) are mostly intended to be administrated intravenously, understanding the interaction of IONPs with vascular endothelial cells is extremely crucial for developing safe application regimes of IONPs. In this work, interactions of three kinds of IONPs to endothelial cells were investigated both in human umbilical vein endothelial cells (HUVECs) and in healthy mice. Both meso-2,3-dimercaptosuccinic acid (DMSA) coated Fe3O4 NPs (DMSA-Fe3O4 NPs) and DMSA-Fe2O3 NPs induced cell growth inhibition, while polyglucose sorbitol carboxymethyether coated Fe2O3 NPs(PSC-Fe2O3 NPs) did not. The PSC coating inhibited the cellular uptake of the IONPs. Both DMSA-Fe3O4 and DMSA-Fe2O3 NPs induced ferroptosis of HUVEC through upregulating phospholipid peroxides, which could be inhibited by typical ferroptosis inhibitors ferrostatin-1, Trolox and deferoxamine. Moreover, transforming growth factor beta 1 (TGFβ1) was upregulated by DMSA-Fe3O4 NPs at protein and gene level. The inhibitor of TGFβ1 receptor LY210 could reduce the effect. When being intravenously injected in mice, DMSA-Fe3O4 NPs were observed locating in the liver, increased the levels of lipid peroxidation (4-hydroxynonenal), acyl-CoA synthetase long-chain family member 4(ACSL4) and TGFβ1, indicating ferroptosis occurrence in vivo. The ferroptosis of vascular endothelial cells in exposure with IONPs depended on the surface coating and core chemistry of the NPs. Both DMSA-Fe3O4 NPs and DMSA-Fe2O3 NPs could induce the ferroptosis of endothelial cells, while PSC-Fe2O3 NPs did not induce ferroptosis and apoptosis possibly due to the very low cellular uptake. DMSA-Fe3O4 NPs and TGFβ1 formed feedforward loop to induce ferroptosis.
研究领域:
纳米技术
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细胞生物学
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药理学
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毒理学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 139
·期 29
·e52649
·
IF 3.057
Chen Gao,Junbo Jiang,Juan Wang,Yutong Wang,Yangyang Zhang,Caihua Rao,Yue Cheng,Zhongrong Chen,Runhuai Yang,Gang Zhao
Mineralization of hydroxyapatite mineralized by acidic metal oxides has attracted substantial research interest in the research and development of orthopedic substitutes. In this study, Polycaprolactone (PCL) nanofibers with nano-tantalum oxide (Ta 2 O 5 ) were successfully fabricated through electrospinning. The scaffold simulates the mineralization process of hydroxyapatite in simulated body fluid. However, in the process of mineralization, there is a chemical reaction between hydrophobic scaffolds and acid oxides, which is believed to have a significant impact on the biological effects of the scaffolds. The results of SEM, EDS, XRD, Mapping, FTIR, GPC, 13 CNMR, and 1 HNMR explain the principle of hydroxyapatite mineralization by Ta 2 O 5 and the reason why the composite scaffold is blurred, that is, the carbonyl carbon of PCL attacked by the surface hydroxyl groups of Ta 2 O 5 to catalyze its ring-opening polymerization to synthesize PCL/Ta 2 O 5 nanocomposites in one step. In order to accurately explore the effect of this reaction on the metabolism of biological macromolecules in the future, we provide a detailed route of Ag Nanoparticles -Dimercaptosuccinic acid@Transcription activator (AgNPs-DMSA@TAT) probe synthesis. The results provide a reference for the sedimentation of hydroxyapatite induced by acid oxides and its effect on traditional electrospun fiber scaffolds.
研究领域:
材料科学
·
生物材料
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骨科
·
生物医学工程
✓ 已验证
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 99
·96635-96643
·
IF 3.289
Peng Zhao,Meng Cao,Lina Song,Hao Wu,Ke Hu,Bo Chen,Qiwei Wang,Ning Gu
Magnetic nanoparticles (MNPs) are widely used in biomedical applications in vivo. However, the endocytosis of mononuclear phagocyte system (MPS) is still a major challenge for MNPs delivery in vivo. MIM (MTSS1) is a multifunctional scaffold protein to regulate both actin dynamics and membrane dynamics, which may decide the readily particles clear ability of MPS and be implicated in the cellular endocytosis. To find out the exact role of MIM plays in the nanoparticle uptake process of macrophages, we established a MIM knock-down cell line RAW 264.7MIM-. The endocytosis rate and efficiency were detected to find out the differences between the normal RAW 264.7 and RAW 264.7MIM- cell after 24 h of exposure to the Fe2O3@DMSA MNPs (70 nm hydrodynamic size). The results indicated that the clathrin-mediated endocytosis of RAW 264.7MIM- cell involves fewer particles than normal RAW 264.7 cells with significant differences in the concentration ranging from 100 to 200 μg mL−1. Therefore, knock-down the MIM expression in macrophage would affect the endocytosis process to iron oxide nanoparticles mainly in clathrin-mediated pathway. As a whole, our results presented here illustrated that MIM plays a positive role in the cellular endocytosis process of MNPs, which is a meaningful molecular basis for biomedical applications of nanomaterials.
研究领域:
生物医学工程
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细胞生物学
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
·
2020
·
IF 3.085
Xiaowei Liu,Yuan Ai,Qian Chen,Sheng Liu
Lead sulfide (PbS) has drawn research interest due to its excellent optical, thermoelectric, and other physical properties. Various methods have been developed to synthesize PbS nanoparticles (NPs) for application in a variety of fields. However, most of these methods either require complex experimental conditions or are inefficient. Here, a highly efficient approach to synthesize PbS NPs, inspired by using 2,3-dimercaptosuccinic acid (DMSA) as a heavy metal chelator to treat lead, mercury, and arsenic poisoning, is reported. DMSA can attach to protein-based materials, such as human hair, using disulfide bonds (–SS–) as reaction sites. DMSA tethered to the protein-based materials can further chelate with Pb 2+ to assist in the formation of PbS NPs. Characterization of the synthesized PbS NPs demonstrated clear crystallization and uniform distribution. Furthermore, the new method is much more efficient than those previously reported, which can greatly improve the production of PbS NPs for a broad range of applications. Moreover, detailed analysis shows that all protein-based materials can function as templates for synthesizing PbS NPs due to the prevalent existence of –SS– in the natural materials.
研究领域:
材料科学
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纳米技术
·
化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）