Analytical Methods
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2026
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IF 2.6
Bingyu Fu,Yanru Shao,Zhixiong Zheng,Shengxin Wen,Yingli Guo,Qi Xu,Hualin Yang
In this study, a simple and sensitive dual-mode biosensor was designed based on the color of 2,6-dichloroindiphenol (DCIP) and the fluorescence of calcein. The target alkaline phosphatase (ALP) can catalyze the dephosphorylation of L-ascorbic acid-2-phosphate (AAP) to form ascorbic acid (AA) and phosphate ions. The reducing properties of AA can reduce the DCIP from blue to colorless. Meanwhile, phosphate ions can chelate with europium ions (Eu 3+ ) to restore the fluorescence of Eu 3+ -Calcein. In colorimetric mode, the linear detection range for ALP was 1.56-50 U/L with a limit of detection (LOD) of 0.27 U/L. In fluorescence mode, the linear detection range was 0.78-25 U/L and LOD was 0.23 U/L. Besides, the selectivity of this dual-mode for ALP was very excellent and the recovery rates in serum samples were also satisfactory.
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高影响因子
Science China-Technological Sciences
·
2022
·Vol. 65
·期 5
·1043-1051
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IF 3.903
Yang Sen,Pan XiaoRui,Tang JianPu,Yao Chi,Yang DaYong
Supramolecular DNA hydrogels have been synthesized based on the assembly of DNA building-blocks such as branched DNA and long DNA chains. The structures and functions of sole-module DNA hydrogels remain limitations. New methodologies by integrating hybrid components are desired to expand the synthesis of DNA hydrogel. Herein, we synthesized a Ln 3+ -containing luminescent supramolecular hydrogel by employing the coordination and electrostatic interactions between lanthanide ions (Tb 3+ and Eu 3+ ) and linear single-stranded DNA (ssDNA). Through the coordination between ssDNA and Ln 3+ , a series of luminescent supramolecular hydrogels were synthesized, among which the Tb-G n /T n and Eu-T n hydrogels emitted the characteristic luminescence of Tb and Eu, respectively. The luminescent intensities of the hydrogels were adjusted by designing DNA sequences with programmable bases and chain lengths. Notably, the Tb/Eu co-doped luminescent supramolecular hydrogel displayed tunable luminescence from green to yellow by regulating the stoichiometric ratio of Tb/Eu. Moreover, the hydrogel had reversible luminescent stimulation responsiveness toward Ag + /L-Cys. We expected that the synthesis of Ln 3+ -containing luminescent supramolecular hydrogels enriched the strategies of the construction of DNA hydrogels, and promoted the development of stimuli-responsive supramolecular materials.
研究领域:
材料科学
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化学
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纳米技术
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生物物理
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ADVANCED FUNCTIONAL MATERIALS
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2024
·
IF 18.5
Junyu He,Tongqing Sun,Min Li,Anshi Chu,Xiujuan Zhuang
The realization of stable single-component white light emission in metal halide perovskites is still challenging due to the fast halide ion migration and narrow luminescence bands. In this work, all-inorganic single CsPbCl x Br 3−x perovskite microplates with stable red-blue-green triple color light emission are prepared by introducing europium ions Eu 3+ as dopants. Eu doping effectively suppresses ion migration and enables two spatially separated halide phases with stable dual-wavelength emissions. Furthermore, the incorporation of Eu 3+ compensates for the absence of red-light emission, thereby yielding a superior white emission with exceptional quality. The color rendering index of triple-color-emitting perovskites can be tuned successfully by controlling the halogen ratios, and the optimal microplate achieved a Commissions Internationale de l’Eclairage (CIE) coordinates of (0.32, 0.32). The results present a new enlightenment for the preparation of low-cost single-component white light materials.
研究领域:
材料科学
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光电
·
光子学
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APPLIED ORGANOMETALLIC CHEMISTRY
·
2024
·
IF 3.7
Zixuan Zhou,Yuhan Jiang,Xin Luo,Ying Zhang,Lei Wang,Yaguang Sun,Jingwei Liu,Mingchang Zhu,Jinchao Cao,Shuangyan Wu
Milk, owing to its nutritional value, is a staple commodity in daily life. Ensuring its integrity and authenticity is paramount for researchers and the food industry. To evaluate spoilage and adulteration of milk, we proposed a robust and reliable optical method to guarantee milk quality by utilizing riboflavin as an internal biomarker. By precisely controlling the content of Eu 3+ , Tb 3+ , and Gd 3+ ions, a two-dimensional ratiometric luminescence lanthanide coordination polymer (Ln-CP) with adjustable emission centers was synthesized for the detection of riboflavin (RF), leveraging a Förster resonance energy transfer (FRET) and photoinduced electron transfer (PET) process. This method demonstrates high sensitivity and selectivity towards RF and has been successfully applied to the detection of RF in both milk and calf serum.
研究领域:
分析化学
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食品科学
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材料科学
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FOOD CHEMISTRY
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2020
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IF 6.306
Fei Qu,Han Wang,Jinmao You
Herein, a new type of coordination polymer networks (CPNs), where both of 2,6-Pyridinedicarboxylic acid (DPA) and guanylate monophosphate (GMP) chelate with Eu 3+ , are firstly synthesized (GMP/Eu/DPA). After mixing with GMP/Tb CPNs, a novel ratiometric dual lanthanide nanoprobe is constructed. Alkaline phosphohydrolase (ALP) specifically induces the cleavage of phosphate ester group in GMP. Therefore, the addition of ALP causes the fluorescence quenching of GMP/Tb, and then the emissions of GMP/Eu/DPA enhance as the result of the formation of Eu/DPA complexes. Glyphosate, as an organophosphorus pesticide, can vehemently inhibit the catalytic activity of ALP, so a ratiometric detection of glyphosate can be achieved with a linear range from 0.015 to 8.45 μg/mL. The present strategy also shows good recoveries for measuring glyphosate in rice, millet, soybean, milk, tap water, and mountain spring water, suggesting a great potential for applications in foods.
研究领域:
分析化学
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食品科学
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环境科学
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ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Chang Liu,Dingkun Lu,Xinrui You,Guoyue Shi,Jingjing Deng,Tianshu Zhou
Herein, a novel ratiometric fluorescent probe based on [email protected] /GMP ICP nanoparticles was developed for the detection of Aβ monomer in rat as a biomarker for Alzheimer’s disease (AD) by fully exploring the competitive coordination interaction and by taking advantage of excellent optical property of carbon dots sensitized lanthanide infinite coordination polymer (ICP) nanoparticles. The carbon dots (CDs) with abundant functional groups were encapsulated into Eu/GMP ICPs through self-adaptive chemistry , which could not only sensitize the red fluorescence of Eu/GMP ICPs effectively, but also act as an internal reference for self-correction. In the absence of Cu 2+ , the as-formed [email protected] /GMP ICPs exhibited the characteristic emission of CDs at 400 nm and strong emission of Eu 3+ at 592 nm, 615 nm, 650 nm and 694 nm. With the addition of Cu 2+ , the red fluorescence of Eu 3+ decreased due to the coordination interaction between CDs and Cu 2+ , thus destroyed the antenna effect. After the subsequent addition of Aβ monomer, the specific binding occurred between Cu 2+ and Aβ monomer, and then the red fluorescence of Eu 3+ restored again. During this process, the fluorescence of CDs remained unchanged, thus could be used as an internal reference to cancel out the environmental fluctuation and was more adaptive for the detection of Aβ monomer in biological fluids. The method demonstrated here was highly sensitive, free from the interference of other species in rat brain, the in vivo analysis of Aβ monomer in CSF and different brain regions from normal rats and Alzheimer’s rats could be realized, which was of great significance for better understanding the mechanism of AD and paving the way to understand the chemical essence involved in AD.
研究领域:
纳米技术
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荧光光谱
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生物标志物检测
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神经退行性疾病
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Wen-Jie Wu,Qi Zhao,Rui Zhou,Ya-Chuan Liang,Wen-Bo Zhao,Chong-Xin Shan
An europium functionalized ZnO quantum dots (QDs) ratiometric fluorescent nanoprobe is designed to establish a real time, on-site visual, and highly sensitive probe method for tetracycline (TC). The yellow-emitting ZnO QDs serves as the internal reference, while the Eu 3+ chelated on the surface of ZnO QDs is used as the signal reporting unit. This nanoprobe exhibits rapid response, excellent selectivity, and high sensitivity with a detection limit of 4 nM in detecting the levels of TC. In addition, fluorescence of the nanoprobe can change from yellow to red as the concentration of TC increases. Thus, naked eye detection of TC was realized using the test paper processed by nanoprobe, followed by RGB value analysis function on the mobile phone APP.
研究领域:
分析化学
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纳米技术
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环境科学
·
生物技术
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2022
·
IF 4.831
Huifang Wu,Yuwei Ling,Shiying Ju,Yubing Chen,Mengqi Xu,Yanfeng Tang
Phosphate (Pi) plays an essential role in aquatic ecosystems as well as in physiological processes. Here, a dual-emission probe for the sensitive, specific and visual analysis of Pi is fabricated by coordinating Eu 3+ with luminol and 2,6-pyridinedicarboxylic acid (DPA). Pi can significantly enhance the characteristic fluorescence of Eu 3+ at 615 nm by promoting energy transfer from DPA to Eu 3+ and reducing the quenching effect of water molecule, luminol with inherent emission at 423 nm further enhances the Eu 3+ fluorescence. Accordingly, ratiometric detection of Pi can be achieved with the fluorescence ratio F 615 /F 423 as a function of Pi concentration. Linearity between F 615 /F 423 and Pi concentration in the range of 0.1–25 μM is shown, and the limit of detection (LOD, 3σ/K) for Pi is 0.027 µM. In addition, a continuous change in the fluorescence color of the probe from blue to red is observed with increasing Pi concentration under a UV lamp, and a smartphone-based visual method is used for the convenient and effective semi-quantitative determination of Pi. The dual-emission probe has been successfully applied to ratiometric and visual analysis of Pi in human urine and environmental water samples, and adequate results are obtained.
研究领域:
分析化学
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环境科学
·
生物医学工程
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Qian Zhang,Wanyin Ge,Xinmeng Zhang,Yie Tian,Zheng Yin
White light-emitting diodes (WLEDs) are promising candidates for environment-friendly solid-state light sources, where modulation of white light has been a significant research priority. Here we achieved a new single-phase white light phosphor (Si NPs-M) by grafting silicon-based nanoparticles onto a red lanthanide coordination polymer by a simple wet chemical method . The activation of the energy transfer mechanism is controlled by changing the local site of ion coordination (by varying the Eu 3+ concentration) to achieve modulation of the molecule to fine-tune its emitted chromaticity. The synthesis of a single-phase phosphor based on ultraviolet (UV) pumped and as a WLED was realized. These WLEDs demonstrate white light for color coordinates of (0.3405, 0.3682), CRI of 78, and CCT of 5210 K. In addition, the WLEDs possess good optical stability as the drive current increase from 30 mA to 300 mA, while the phosphor maintains 87.4 % of the luminous intensity when the external temperature rises to 130 °C, indicating high stability. This work has potential applications for silicon-compatible display technologies that require fine control of efficient white light emission.
研究领域:
材料科学
·
光电技术
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纳米技术
·
照明工程
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Xuezhen Feng,Chao Wang,Shibin Shang,He Liu,Xujuan Huang,Jianxin Jiang,Haibo Zhang
The development of stimulus-responsive materials with multifunctionality is important for achieving bionic artificial intelligence. However, stimulus-responsive cellulose hydrogels that simultaneously change their shape and fluorescent color under a single stimulus are difficult to fabricate. Here smart, multicolor fluorescent cellulose hydrogels were prepared from cellulose, levofloxacin, epichlorohydrin, and lanthanide ions (Eu 3+ or Tb 3+ ). The hydrogels were incorporated with pan paper into synergetic color-changing and shape-morphing actuators (Eu-CLF and Tb-CLF actuators). Besides fluorescing with the metal ligands, levofloxacin possesses antibacterial activity. The fluorescence color of Eu-CLF hydrogel in Tb 3+ solution changed from red to yellow, whereas that of Tb-CLF hydrogel in Eu 3+ solution changed from green to red. Both the Eu-CLF and Tb-CLF hydrogels fluoresced blue and green in alkali and acid solution, respectively. The actuator thus achieves synergetic color-changing and shape-morphing under a single external stimulus (acidic/alkaline switching). Such an activator shaped like a bionic flower and an intelligent octopus-type soft robot with camouflaging ability were then prepared. This study provides an elegant strategy for developing advanced multi-responsive multicolor tunable behaviors for bionic soft robots, biosensors , and camouflaged robots.
研究领域:
材料科学
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仿生学
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人工智能
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机器人技术
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生物传感器
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高影响因子
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