Versatile iron-vitamin K3 derivative-based nanoscale coordination polymer augments tumor ferroptotic therapy
Ferroptosis is a newly form of regulated cell death, which has attracted great attention for tumor therapy. Herein, we prepared nanoscale coordination polymer Fe-NQA particles to deliver iron and NQA (vitamin K 3 derivative) into tumor cells, which synergistically promoted ferroptotic therapy for inhibiting tumor growth, preventing metastasis, and overcoming radioresistance.
研究领域:
癌症治疗
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纳米技术
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材料科学
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细胞生物学
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高影响因子
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