SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2019
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IF 2.931
Jianping Guan,Qin Tu,Long Chen,Mao-Sen Yuan,Jinyi Wang
Herein, we designed and synthesized a luminophor, Rh-F , which is an intergrant of rhodol and 2-hydroxy benzothiazole by introducing a benzothiazole unit onto the ortho-position of the phenolic hydroxy of rhodol. Rh-F exhibited excellent fluorescence properties such as a large Stokes shift (>180 nm) and the synergistic effect of aggregation-induced emission (AIE) and an excited state intramolecular proton transfer (ESIPT) feature. The AIE/ESIPT mechanism was thoroughly explored using X-ray single-crystal structures and photophysical determinations. Furthermore, Rh-F showed a sensitive fluorescence response to Fe 2+ with low detection limits of 115.2 nM and high selectivity. Studies of its sensing mechanism indicated that the Fe 2+ -induced blue-green fluorescence-quenched at 525 nm originates from an irreversible Fe 2 + chelate with the oxygen atom of the hydroxyl group and the N atom of the benzothiazole moiety. This blocked the ESIPT process of Rh-F which resulted in the quenching of the fluorescence sensor for Rh-F .
研究领域:
化学
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材料科学
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分析化学
✓ 已验证
DOI
PubMed
高影响因子
Journal of Nanomaterials
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2019
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IF 2.233
Jun Li,Shiyao Ma,Xincai Xiao,Dan Zhao
This paper reports the preparation of green-emissioned CDs by a one-step hydrothermal route with DL-malic acid and ethylenediamine as raw materials and further explored the impacts of the amount of reactants, the reaction time, and temperature upon the optical properties of prepared CDs, to select the optimal preparation parameters. The optical properties, surface groups, and element components of the prepared CDs have been systematically studied by UV-Vis absorption spectra, fluorescence spectra, FTIR, EDS, and XPS. The prepared CDs have been applied to realize the fingerprint development, fluorescence ink, and, specifically, the detection of Fe2+ through an inner filter effect with its detection range at .
研究领域:
材料科学
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化学
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产品关联
DOI
高影响因子
Journal of Physical Chemistry C
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2023
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IF 3.7
Chunyu Yu,Xue Li,Xin Qiao,Zhiwei Zhang,Danyang Zhang,Hua Liu,Xue-Li Hao,Zhongzhi Wang,Hongpeng You,Liang Zhou
Fluorescent carbon quantum dots (r-CDs) were synthesized safely and readily by stirring at room temperature with a yield of 76.5%. The synthesized r-CDs exhibit bright green emission with an absolute quantum yield of 12.0% under the excitation of ultraviolet light. Within the pH range of 3–12, the r-CDs exhibit excellent fluorescence stability. Interestingly, the fluorescence intensity of r-CDs faded promptly when the pH value diminished to 2 and then regained when the pH value returned to 3. This means that r-CDs can be used as “on–off–on” fluorescent probes for pH sensing. The mechanism of this sensitive pH response behavior was discussed in detail, and a possible mechanism of protonation–deprotonation–protonation processes was proposed. In addition, we have proposed a green preparation route for eco-friendly filter paper using anticounterfeiting. Interestingly, the presence of Fe2+ significantly quenched the fluorescence of r-CDs. Experimental results demonstrated the r-CDs can also be used to detect the content of Fe2+ in water, and the detection limit was 8.82 μM/L.
研究领域:
化学
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材料科学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Dequan Wei,Shenghua Lv,Jingjing Zuo,Shan Liang,Jialin Wang,Tingxiang He,Leipeng Liu
Chitosan, as a natural biomass material, is green, recyclable, sustainable and well biocompatible. The molecular chain is rich in active groups such as amino and hydroxyl groups, and its preparation of fluorescent probes has the advantages of biocompatibility and efficient detection performance. In this study, a bis(benzaldehyde) (BHD) fluorescent functional molecule was designed. Then a series of fluorescent chitosan-based hydrogel films (CSBHD) were prepared using chitosan as raw material and BHD as cross-linking agent. As a fluorescent probe for metal ions, CSBHD was able to efficiently detect Fe 2+ with a linear correlation of fluorescence intensity in the range of 0–160 μM, and the limit of detection (LOD) was 0.55 μM. Moreover, it has excellent adsorption performance for Fe 2+ ions, with a maximum adsorption capacity of 223.5 g/mg at 500 mg/L Fe 2+ concentration. Finally, we characterised the structure and microscopic morphology of CSBHD films and found that CSBHD as a hydrogel film has a high cross-linking density, good water resistance, excellent thermal stability, strong resistance to swelling, and excellent stability in cycling tests. Hence, it has great potential for application in adsorption and detection of Fe 2+ ions. It also provides a good strategy for the application of chitosan based fluorescent probe materials in environmental monitoring and heavy metal ion adsorption.
研究领域:
材料科学
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环境科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
ACS Applied Polymer Materials
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2021
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IF 4.089
Weiming Ji,Shunni Dong,Wei Fan,Chao Lv,Jingjing Nie,Binyang Du
A functional monomer, namely, 1-hexene-4-(benzal-2,2′:6′,2″-terpyridines)pyridinium bromide (HTP) was synthesized and incorporated into the cross-linking network of microgels. The HTP-functionalized microgels (HTP-MGs) were synthesized by surfactant-free emulsion copolymerization with N-isopropylacrylamide as the main monomer, 1-vinylimidazole as a quaternization cross-linkable comonomer, HTP as the functional comonomer, and 1,6-dibromhexane as the quaternization agent. The obtained HTP-MGs were spherical with a hydrodynamic radius Rh of 205 ± 2 nm and uniform size distribution in HEPES buffer aqueous solutions at 25 °C. The HTP-MGs exhibited a characteristic UV–vis absorption peak at 315 nm and a characteristic fluorescent emission peak at 430 nm, respectively. The HTP-MGs can selectively, sensitively, and optically respond to Fe2+ ions in aqueous solution with a fast response time of 3 s in wide pH (2–10) and temperature (25–50 °C) ranges, resulting in a color change in HTP-MG HEPES buffer aqueous solutions from colorless to purplish red, which can be easily distinguished by naked eyes. A linear concentration range of 0–14 μM and a detection limit (DL) of 82 nM were achieved for detecting Fe2+ ions in HEPES buffer aqueous solutions (pH = 7) at 25 °C. The molar binding ratio of the HTP moiety within HTP-MGs to Fe2+ ions was 2:1, as revealed by Job’s plot. It was found that the coexistence of 15 species of other metal ions except of Cu2+ ions studied here did not affect the detection of Fe2+ ions. Furthermore, a fluorescent emission peak at 371 nm with strongly enhanced fluorescent intensity was observed for HTP-MG HEPES buffer aqueous solutions with the addition of Zn2+ or Cd2+ ions. By combining the optical response to Fe2+ ions and fluorescent response to Zn2+ ions, it was demonstrated that HTP-MGs could also have potential applications in the fields of encryption and anti-counterfeiting.
研究领域:
材料科学
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分析化学
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DOI
高影响因子
Microsystems & Nanoengineering
·
2025
·Vol. 11
·期 1
·1-10
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IF 9.9
Ma Yanmei,Li Xinhao,Hu Weikang,Ruan Muyang,Yang Ming,Chang Lingqian,Gu Hongri,Hu Chengzhi
Ferroptosis is an iron-dependent form of regulated cell death driven by phospholipid peroxidation and the accumulation of reactive oxygen species (ROS), holding significant importance for therapeutic applications via its induction or inhibition. Accurate detection of intracellular Fe 2+ and ROS is essential, as these molecules play essential roles in initiating and propagating ferroptosis. In this study, we present a novel electrochemical nanoprobe for real-time, highly selective detection of intracellular Fe 2+ . The nanoprobes are prepared by coating gold nanoparticles (AuNPs) and poly(3,4-ethylenedioxythiophene) (PEDOT) onto silicon carbide nanowires (SiC NWs), which are subsequently functionalized with ferrocenyl endoperoxide carboxylic acid (FDCA) and integrated with a liquid metal-filled glass nanopipette. FDCA is specifically synthesized to enable precise electrochemical detection of Fe 2+ with high selectivity (0.1 nM to 1 µM) and exceptional specificity. PEDOT and AuNPs can improve electrical conductivity and provide a versatile interface for further FDCA decoration. We use the nanoprobes to evaluate the intracellular change of Fe 2+ in MCF-7 breast cancer cells during erastin-induced ferroptosis. We observe a significant increase in intracellular Fe 2+ levels in MCF-7 cells undergoing ferroptosis, accompanied by a notable rise in ROS levels. These findings underscore the potential of this nanoprobe to enhance our understanding of the mechanism of ferroptosis in tumor development and as a potential treatment target.
研究领域:
生物化学
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细胞生物学
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肿瘤学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL BIOCHEMISTRY
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2023
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IF 2.9
Ye Sun,Guangda Xu,Yue Wang,Peng Song,Yao Zhang,Lixin Xia
Herein, we developed a concise, time-efficient, and high selective assay for detecting Fe 2+ through its triggered surface plasmon-assisted reduction reaction of p -nitrothiophenol (PNTP) to p,p ′-dimercaptoazobenzene (DMAB) on the surface of gold nanoparticles (AuNPs) based on surface-enhanced Raman scattering (SERS) spectroscopy. When Fe 2+ was added to the PNTP-AuNPs system, the appearance of three characteristic peaks at 1142, 1392, and 1440 cm −1 attributed to DMAB demonstrated that Fe 2+ induced the catalytic coupling reaction of PNTP. The Raman intensity ratio of the peak at 1142 cm −1 to the peak at 1336 cm −1 and the concentration of Fe 2+ presented a good linear response from 10 to 100 μM with a limit of detection (LOD) of 0.35 μM. More importantly, the entire detection process can be completed within 2 min and further successfully used for the detection of Fe 2+ in river water.
研究领域:
分析化学
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纳米技术
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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