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A colorimetric sensor of cysteine based on self-assembly nanostructures of Fe3+-H2O2/Tetramethylbenzidine system with “On-Off” switching function

Zhonghua Xue,Xiaofen Wang,Honghong Rao,Xiuhui Liu,Xiaoquan Lu

Many strategies have been explored for selectively and sensitively detecting cysteine in different samples. Here, a novel colorimetric sensor based on self-assembly nanostructures of Fe 3+ -H 2 O 2 /Tetramethylbenzidine system with dual-level logic gate function and colorimetric determination of cysteine were firstly explored. The proposed Fe 3+ -H 2 O 2 -TMB system provides a sensitive optical signal due to the selectively reductive ability of cysteine to the oxidized TMB and thus could be successfully applied to the construction of instant on-site visual detection method with a paper based test strip for cysteine determination in a sample solution as well as for a dual-level logic gate fabrication.