JOURNAL OF MOLECULAR LIQUIDS
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2020
·
IF 5.065
Lijun You,Ke Xu,Guanjun Ding,Xinming Shi,Jumei Li,Shaoyun Wang,Jiabin Wang
Magnetic covalent organic framework modified by Fe 3 O 4 nanoparticles (Fe 3 O 4 @COF) were facile synthesized and used as adsorbent for the adsorption of bisphenols from aqueous solutions. The Fe 3 O 4 @COF is synthesized by catalyst-free Schiff base reaction of melamine and terephthalaldehyde, and synthesis strategy is flexible and controllable. The as prepared Fe 3 O 4 @COF was characterized by TEM , PXRD , TGA and BET analysis. The Fe 3 O 4 @COF possessed large specific surface area (335.2 m 2 /g), high chemical and thermal stability, and high saturation magnetization (49.6 emu/g), which in favor of rapid magnetic separation and efficient adsorption in the adsorption process. The effects of temperature, adsorbent dosage, pH and salt concentration on the adsorption of bisphenols (BPA and BPAF) were studied. The as-prepared adsorbent showed an excellent adsorption ability for BPA and BPAF , and the max adsorption capacity of BPA and BPAF could reach 140 and 290.4 mg/g. The adsorption kinetic fitted the pseudo-second-order kinetic model and the adsorption isotherm followed the Freundlich isotherm equation. Moreover, the Fe 3 O 4 @COF presented favorable re-use performance, which kept over 81.4% removal efficiency of bisphenols after five consecutive recycles. The high adsorption performance and reusability make the Fe 3 O 4 @COF a promising adsorbent for the removal of bisphenols.
研究领域:
材料科学
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环境科学
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化学工程
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2024
·
IF 8
Jialin Zhang,Ming Zhou,Linna Yang,Bin Huang,Kangqiang Lu,Herui Wen,Jiali Ren
Foodborne bacterial infections pose serious threats to human health, leading to illnesses and even fatalities. The key to solve this problem is to develop fast and effective sensor for sensitive detection of bacteria. In this study, an electrochemical biosensor based on magnetic nanocomposite material Fe 3 O 4 @COF-AuNPs and trigging isothermal circular amplification (TICA) was constructed for detection of foodborne bacteria. In this design, a hairpin aptamer probe (HAP)-bound DNA monolayer was designed, serving as the substrate for the electrode to increase surface area. The Escherichia coli ( E. coli ) was selected as the target. The presence of E. coli caused the configuration change of the HAP and allowed the occurrence of TICA with the use of the Klenow Fragment polymerase (KF-Poly), thus the HAPs were away from the DNA monolayer. After adding the catalytic magnetic nanocomposite material Fe 3 O 4 @COF-AuNPs, it was immobilized on the DNA monolayer of the electrode through DNA complementary pairing and exhibited high electrocatalytic behavior towards the reduction of 4-nitrophenol. This enabled ultrasensitive detection of E. coli , with the detection limit (LOD) as low as 10 CFU/mL. The detection time was 1 h. This designed electrochemical sensor showed high selectivity, stability, and reproducibility, which offered a new avenue for detection of foodborne bacteria.
研究领域:
生物传感技术
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食品安全检测
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微生物学
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2023
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IF 6.2
Jutao Hu,Xiaoyu Su,Lei Yuan,Kaiyi Zheng,Xiaobo Zou,Zongbao Sun,Xuechao Xu,Wen Zhang
Accurate and sensitive detection of chloramphenicol (CAP) in natural samples is essential for ensuring human health. Herein, an enzyme-regulated fluorescence sensor using Fe 3 O 4 @COF/Fe 3+ probe, is developed for CAP determination. Fe 3 O 4 @COF, synthesized via hydrothermal method , exhibits dual functions as a magnetic carrier and signal probe. Bovine serum albumin conjugated-chloramphenicol, adsorbed on the surface of Fe 3 O 4 @COF, competes with CAP for antibody binding. The antibody interacts with alkaline phosphatase via the biotin-streptavidin system. Meanwhile, ascorbic acid , produced from the enzyme-catalyzed reaction dominated by alkaline phosphatase, effectively restores the fluorescence of Fe 3 O 4 @COF that is quenched by Fe 3+ . After experimental verification and gradual optimization, a logarithmic linear relationship between CAP concentration and fluorescence intensity is established in the range of 2 × 10 −4 ∼10 μg mL −1 , with a good limit of detection (9.2 × 10 −5 μg mL −1 ). Proposed method exhibits excellent stability (15 days) and reusability (8 cycles), providing a sensitive and reliable method for accurate CAP detection. The readouts show good agreement with HPLC and recoveries during laboratory and natural CAP analysis.
研究领域:
分析化学
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生物化学
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环境科学
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食品安全
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 2
·1-9
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IF 5.479
Deng Ze-Hui,Wang Xia,Wang Xiao-Li,Gao Cui-Ling,Dong Liang,Wang Ming-Lin,Zhao Ru-Song
A magnetic covalent organic framework (Fe 3 O 4 @COF) with core–shell structure was fabricated at room temperature and used as an adsorbent for magnetic solid-phase extraction of polar endocrine-disrupting phenols (4-n-nonylphenol, 4-n-octylphenol, bisphenol A and bisphenol AF). The sorbent was characterized by transmission electron microscopy, FTIR, powder X-ray diffraction and other techniques. The main parameters governing the extraction efficiency were optimized. The phenols were quantified by HPLC with fluorometric detection. The method has attractive features such as low limits of detection (0.08–0.21 ng.mL −1 ), wide linear ranges (0.5–1000 ng.mL −1 ), and good repeatability (intra-day: 0.39%–4.99%; inter-day: 1.57%–5.21%). Satisfactory results were obtained when the developed method was applied to determine the four target pollutants in real world drink samples with spiked recoveries over the range of 81.3~118.0%. This indicates that the method is a powerful tool for the enrichment and determination of endocrine-disrupting phenols in drink samples.
A magnetite based covalent organic framework (Fe 3 O 4 @COFs) was synthesized with TPAB, TPA and Fe 3 O 4 . It was used for magnetic solid-phase extraction of endocrine-disrupting phenols from plastic-packaged tea drink samples coupled with liquid chromatography (LC) for determination.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
Biotechnology for Biofuels
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2021
·Vol. 14
·期 1
·1-12
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IF 6.04
Zhou Zi-Wen,Cai Chun-Xian,Xing Xiu,Li Jun,Hu Zu-E.,Xie Zong-Bo,Wang Na,Yu Xiao-Qi
Background Production of biodiesel from renewable sources such as inedible vegetable oils by enzymatic catalysis has been a hotspot but remains a challenge on the efficient use of an enzyme. COFs (Covalent Organic Frameworks) with large surface area and porosity can be applied as ideal support to avoid aggregation of lipase and methanol. However, the naturally low density limits its application. In this work, we reported a facile synthesis of core–shell magnetic COF composite (Fe 3 O 4 @COF-OMe) to immobilize RML ( Rhizomucor miehei lipase), to achieve its utilization in biodiesel production. Result This strategy gives extrinsic magnetic property, and the magnetic COFs is much heavier and could disperse in water medium well, facilitating the attachment with the enzyme. The resultant biocomposite exhibited an excellent capacity of RML due to its high surface area and fast response to the external magnetic field, as well as good chemical stability. The core–shell magnetic COF-OMe structure not only achieved highly efficient immobilization and recovery processes but also maintained the activity of lipase to a great extent. RML@Fe 3 O 4 @COF-OMe performed well in practical applications, while free lipase did not. The biocomposite successfully achieved the production of biodiesel from Jatropha curcas Oil with a yield of about 70% in the optimized conditions. Conclusion Magnetic COFs (Fe 3 O 4 @COF-OMe) for RML immobilization greatly improved catalytic performance in template reaction and biodiesel preparation. The magneticity makes it easily recovered and separated from the system. This first successful attempt of COFs-based immobilized enzyme broadened the prospect of biodiesel production by COFs with some inspiration.
研究领域:
生物化学
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材料科学
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可再生能源
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2021
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IF 4.821
Wei Wei,Qiang Han,Sheng Tian,Yanping Wang,Huiying Zhang,Haibo Wang,Qionglin Liang
The separation of active ingredients in traditional Chinese medicine (TCM) is of great significance in determining the efficacy of TCM as well as the pharmacological study of active ingredients, improving the scope of application of TCM and the efficiency of disease prevention and treatment. In the current study, we have successfully synthesized a core–shell structure magnetic microsphere Fe 3 O 4 -COF for the separation of α-asarone and β-asarone in the combined decoction of Acorous Tatarinowii Rhizoma (ATR) and Polygalae Radix (PR). The successful synthesis of Fe 3 O 4 -COF was demonstrated chemically and morphologically by using five characterizations such as Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM). Extraction conditions were investigated and optimized, including adsorbent dosage, adsorption time, sample pH value, elution solvent, elution time and volume of elution solution. Under the optimal experimental conditions, we got a low limit of detection (LOD) of α-asarone and β-asarone were 0.0379 μg/mL and 0.0432 μg/mL, and the relative standard deviations (RSD) were less than 2.3%. And the number and intensity of impurity peaks in the chromatogram after extraction of complex samples were significantly reduced and the good recoveries were still maintained after multiple extractions of complex samples, which showed satisfied specific adsorption and excellent resistance to matrix interference. The successful establishment of this method will provide a new direction for the separation and analysis of active ingredients in traditional Chinese medicine.
研究领域:
药学化学
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分析化学
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中药学
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 7
·1-11
·
IF 6.232
Sun Qianqian,Gao Chaohong,Ma Wende,He Yanting,Wu Jie,Luo Kailong,Ouyang Dan,Lin Zian,Cai Zongwei
Core-shell structured magnetic covalent organic framework (Fe 3 O 4 @COF) nanospheres were rapidly synthesized at room temperature using the monodisperse Fe 3 O 4 nanoparticles (NPs) as magnetic core and benzene-1,3,5-tricarbaldehyde (BTA) and 3,3′-dihydroxybenzidine (DHBD) as two building blocks (denoted as Fe 3 O 4 @BTA-DHBD), respectively. They can serve as a mass spectrometry probe for rapid and high-throughput screening of bisphenols (BPs) from pharmaceuticals and personal care products (PPCPs) by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS). The Fe 3 O 4 @BTA-DHBD nanospheres showed some superior features involving average pore size distribution (2.82 nm), high magnetization values (42.5 emu g −1 ), high specific surface area (82.96 m 2 g −1 ), and good chemical/thermal stability. It was used as both ideal adsorbent for enrichment of BPs and new substrate to assist ionization in SELDI-TOF-MS. The method exhibited good linearity in the range 0.05–4000 ng mL −1 with correlation coefficients ( r ) higher than 0.9920. Low limits of detection (LODs) (500 pg mL −1 for bisphenol A (BPA), 2 pg mL −1 for bisphenol B (BPB), 28 pg mL −1 for bisphenol C (BPC), 60 pg mL −1 for bisphenol F (BPF), 33 pg mL −1 for bisphenol AF (BPAF), 200 pg mL −1 for bisphenol BP (BPBP), 10 pg mL −1 for bisphenol S (BPS), 90 pg mL −1 for tetrabromobisphenol A (BPA(Br) 4 ), and 380 pg mL −1 for tetrabromobisphenol S (BPS(Br) 4 )) and good recoveries (80.6–115%) of BPs in PPCPs were achieved. The relative standard deviations (RSDs) of spot-to-spot ( n = 10) and sample-to-sample ( n = 5) were in the ranges 5–11% and 5–12%, respectively. The dual-function platform was successfully applied to the quantitative determination of BPs in PPCPs. It not only expanded the scope of the application of COFs but also provided an alternative strategy for the determination of hazardous compounds in PPCPs.
Schematic representation of the synthesis of core-shell structured magnetic covalent organic framework nanospheres (Fe 3 O 4 @COFs) and its application in the analysis of bisphenols by using Fe 3 O 4 @BTA-DHBD nanospheres as a MS probe based on surface-enhanced laser desorption/ionization time-of-flight mass spectrometry.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF POROUS MATERIALS
·
2021
·Vol. 29
·期 1
·169-179
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IF 2.496
Pang Yue-Hong,Yang Nian-Ci,Qiao Jin-Yu,Shen Xiao-Fang,Huang Yu-Ying
Benzo[a]pyrene (BaP), one of the polycyclic aromatic hydrocarbons with potential carcinogenic, mutagenic and teratogenic toxicity, have been widely concerned. Herein, we report a simple and rapid co-precipitation method for the synthesis of magnetic covalent organic framework (Fe 3 O 4 /COF-DQTp) adsorbent for BaP removal. The magnetized COF-DQTp was characterized by fourier transform infrared, X-ray diffractometer, Brunauer–Emmett–Teller, vibrating sample magnetometer, transmission electron microscopy, high angle annular dark field scanning transmission electron microscopy image and energy-dispersive X-ray spectroscopy elemental mapping. Under the optimized adsorption conditions, the adsorption efficiency was as high as 99% and the maximum adsorption capacity is 19 mg/g in 10 min. The adsorption kinetics shows that adsorption of BaP onto Fe 3 O 4 /COF-DQTp follow pseudo-second order kinetic model. Moreover, the prepared Fe 3 O 4 /COF-DQTp has good reusability and is a potential material for the adsorption of BaP.
研究领域:
环境科学
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材料科学
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化学工程
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产品关联
DOI
高影响因子
TALANTA
·
2023
·
IF 6.1
Zichen Yang,Guoqing Chen,Chaoqun Ma,Jiao Gu,Chun Zhu,Lei Li,Hui Gao
Quinolone antibiotics have good antibacterial properties and are commonly used antibiotics in the dairy industry. Currently, the problem of excessive antibiotics in dairy products is very serious. As an ultra-sensitive detection technology, Surface-Enhanced Raman Scattering (SERS) was applied to the detection of quinolone antibiotics in this work. In order to classify and quantify three antibiotics (Ciprofloxacin, Norfloxacin, Levofloxacin) with highly similar molecular structures, a combination of magnetic COF-based SERS substrate and machine learning algorithms (PCA-k-NN, PCA-SVM, PCA-Decision Tree) was used. The classification accuracy of the spectral dataset could reach 100% and the results of LOD calculation were: CIP: 5.61 × 10 −9 M, LEV: 1.44 × 10 −8 M, NFX: 1.56 × 10 −8 M. This provides a new method for the detection of antibiotics in dairy products.
研究领域:
分析化学
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食品科学
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药物分析
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产品关联
DOI
PubMed
高影响因子
Journal of Cleaner Production
·
2022
·
IF 11.072
Fan Bu,Wei Huang,Mo Xian,Xianlong Zhang,Fengbing Liang,Xiuchu Liu,Xiaoyan Sun,Dexin Feng
Quinolones (QNs) are widely used pharmaceuticals which have been detected in surface water and posed risks to human health. It is important and challenging to develop a novel adsorbent with faster kinetics, higher capacity and easy regeneration. In this work, we creatively designed and synthesized magnetic carboxyl-functionalized covalent organic frameworks (Fe 3 O 4 @COF-TpDBd) as a novel adsorbent for QNs. The adsorption performance and mechanism were investigated. The results showed that the electrostatic interactions between Fe 3 O 4 @COF-TpDBd and QN molecules varied with pH. Therefore, compared with most reported adsorbents, Fe 3 O 4 @COF-TpDBd showed significantly higher adsorption capacities and faster adsorption kinetics under pH-neutral conditions. The kinetics and isotherms experiments proved that the adsorption process was spontaneous and exothermic. The adsorbent can be easily separated from water through magnetism after adsorption. Moreover, the regeneration process can be performed by pH adjustment without any organic solvent or heating, which is more convenient and environmental-friendly than most reported adsorbents. The adsorption capacities remained above 80% after five successive adsorption-desorption cycles. Thus, Fe 3 O 4 @COF-TpDBd has the great potential as a novel adsorbent for QNs removal, which has faster kinetics, higher capacity and easy regeneration.
研究领域:
环境科学
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材料科学
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化学工程
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
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2022
·
IF 9.231
Dan Wei,Ao Pan,Can Zhang,Ming Guo,Chaoyan Lou,Ju Zhang,Huizhen Wu,Xu Wang
A simple, rapid and sensitive vortex-assisted magnetic solid phase extraction (MSPE) method using core–shell structured magnetic covalent organic frameworks (Fe 3 O 4 /COF-TpBD) as adsorbents was established for simultaneous determination of aflatoxins, ochratoxins and enniatins in maize before high-performance chromatography tandem spectrometry detection. Fe 3 O 4 /COF-TpBD was facilely fabricated, characterized, and applied for simultaneous extraction of ten mycotoxins from maize. Key parameters affecting MSPE efficiency were investigated. The method possessed good linearity (0.05–50 μg/kg), high sensitivity (0.02–1.67 µg/kg for limits of detection), and satisfactory recoveries (73.8–105.3 %), with relative standard deviations less than 8.5 %. The amount of adsorbent used (5 mg) and the time required (0.5 min each for adsorption and for desorption) for MSPE were greatly shortened in comparison with the previous reports. Therefore, the fabricated Fe 3 O 4 /COF-TpBD exhibited a great potential for rapid extraction of common mycotoxins in maize, which can be attributed to its multiple interactions with the target mycotoxins.
研究领域:
分析化学
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食品安全
·
真菌毒素分析
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2019
·
IF 3.858
Aying Wen,Guoliang Li,Di Wu,Yanxin Yu,Yan Yang,Na Hu,Honglun Wang,Jian Chen,Yongning Wu
Most of the reported covalent organic frameworks (COFs) are hydrophobic, limiting their adsorption application in sample pretreatment field. In this work, sulphonate functionalized magnetic covalent organic frameworks (COFs) composites were first synthesized by loading gold nanoparticles on Fe 3 O 4 @COF(TpBD) surface and then functionalized by sodium 3-mercaptopropanesulphonate immobilization via Au-S bonding formation (denoted as Fe 3 O 4 @COF(TpBD)@Au-MPS nanocomposites), which were further utilized as adsorbents for magnetic solid-phase extraction (MSPE) of fluoroquinolones. Compared with Fe 3 O 4 @COF(TpBD), the composites exhibited higher affinity to fluoroquinolones. Under optimized conditions, the developed MSPE method coupled with HPLC–MS/MS showed good linearity (R 2 ≥0.9989) and yielded low limits of detection (0.1–1.0 μg kg− 1 ) for fluoroquinolones. Moreover, the proposed method was successfully applied to extract fluoroquinolones from spiked meats (pork, chicken and bovine). The satisfactory recoveries were in the range of 82–110.2% with the relative standard deviations (RSDs) lower than 7.7%. These results indicated that the Fe 3 O 4 @COF(TpBD)@Au-MPS is a promising magnetic adsorbent for trace fluoroquinolones determination in meat samples. This work not only provided a facile strategy for COF functionalization, but also developed an efficient method for detecting fluoroquinolones in foodstuffs.
研究领域:
分析化学
·
材料科学
·
食品安全
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）