Ling Li,Ya Q. Wu,Ke K. Sun,Run Zhang,Lu Fan,Ke K. Liang,Le B. Mao
By exploring the layer-by-layer self-assembly method and the changes of content of graphene oxide (GO), controllable preparation of a new core–shell microsphere Fe 3 O 4 @MOFs/GO was achieved in this work. The prepared composite material was characterized by the XRD , FTIR, and TEM analysis. The application of Fe 3 O 4 @MOFs/GO as drug carrier for ibuprofen was studied. The results suggested that the properties of drug loading and release can be tuned by different layers and content of GO.
Ling Li,Ke Ke Sun,Lu Fan,Wei Hong,Zu Shun Xu,Li Liu
Magnetic core–shell spheres Fe 3 O 4 @MOFs and Fe 3 O 4 @MOFs/GO were prepared using layer by layer assembly method. Fe 3 O 4 @MOFs and Fe 3 O 4 @MOFs/GO were characterized by XRD , FTIR, SEM, TEM and VSM. The results showed that both magnetic spheres were with core–shell structure. The method was proved to be valuable for producing core–shell structure with porous nanocomposite materials as shell. Methylene blue was selected as drug model to study the drug loading of the synthesized spheres. It was found that the addition of graphene oxide (GO) enhanced the drug loading amount of magnetic sphere.