JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2013
·
IF 3.172
Ge Liu,Dan Hu,Min Chen,Changchun Wang,Limin Wu
Multifunctional PNIPAM/Fe 3 O 4 –ZnS hybrid hollow spheres integrating magnetism, luminescence, and temperature responses into one single entity have been successfully fabricated via a facile method. First, the cross-linked Poly (N-isopropylacrylamide) (PNIPAM) hollow spheres were synthesized via a classical method, named one-pot “self-removing” process. Then, Fe 3 O 4 and ZnS nanoparticles were in situ precipitated on the surface of the PNIPAM hollow spheres. The PNIPAM/Fe 3 O 4 –ZnS hybrid hollow spheres exhibit magnetic property, which indicates the potential application in drug targeting. In addition, ZnS nanoparticles in the shell play an important role as a luminescent label for tracking the drug delivery. Meanwhile, the existence of PNIPAM provides a thermosensitive property. All these results indicate that the obtained composite can be expected to be used as a smart drug delivery material.
研究领域:
材料科学
·
生物医学工程
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2014
·Vol. 14
·期 7
·5047-5053
·
IF 1.339
Liu Li,Jiang Wei,Yao Lei,Yang Xi-Wen,Chen Bin-Hua,Wu Shi-Xi,Li Feng-Sheng
A novel Fe3O4@ZnS nanomaterial with fluorescent and superparamagnetic properties has been successfully fabricated via TOPO-TOP synthesis with an additional coordinating component (OAm). The adsorption of OAm on the preformed magnetite nanoparticles, which were
prepared in phenyl ether with oleic acid and oleyl amine, played an essential role in directing the structure of the Fe3O4@ZnS composites. The obtained materials were characterized by FTIR, TEM, XRD, X-ray photoelectron spectroscopy (XPS), UV-vis, fluorescence spectrophotometer
and VSM. The results indicated that the Fe3O4 nanoparticles were successfully combined with ZnS and the coating of ZnS can be controlled by adjusting the molar ratio of Fe3O4 to ZnS. The saturation magnetization values of Fe3O4,
Fe3O4@ZnS (1:2) and Fe3O4@ZnS (1:5) nanoparticles are 57.0 emu g−1, 44.4 emu g−1 and 34.2 emu g−1, respectively at 300 K and the nanocomposites exhibit better fluorescence without evident quenching.
The combined magnetic and fluorescent properties endow the nanocomposites with great potential applications in “nano-conveyer-belt” platform technology for drug targeting, bioseparation, diagnostic analysis and so on.
研究领域:
纳米技术
·
材料科学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2014
·Vol. 14
·期 7
·5426-5429
·
IF 1.339
Yang Peilun,Zhu Baocun,Zhao Jie,Yu Haiqin,Yan Liangguo,Wei Qin,Du Bin
Currently, growing attention has been paid to the sensitive determination and removal of Cu2+ because excessive levels of Cu2+ could do harm to organisms. Herein, a novel diethanolamine-modified magnetic fluorescent Fe3O4@ZnS nanoparticle
(MFNP) for simultaneous detection and removal of Cu2+ was designed and synthesized through dithiocarbamate linkage strategy. The characterization of MFNP was confirmed by transmission electron microscope (TEM), infrared (IR) and emission spectra. The results showed
that MFNP could quantificationally detect Cu2+ with high sensitivity and selectivity under a broad pH range (pH 4.5–9). The removal of Cu2+ was achieved by the aggregation-induced sedimentation (AIS) strategy and by external magnetic field.
研究领域:
分析化学
·
环境科学
·
纳米技术
✓ 已验证
DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2016
·Vol. 16
·期 1
·246-252
·
IF 1.338
Jiang Wei,Chen Binhua,Wu Juan,Xu Shanshan,Tian Renbing
The thermo-sensitive magnetic fluorescent trifunctional nanocomposite (Fe3O4/ZnS@PNIPAM) has been synthesized via a facile route. The obtained biocompatible nanocomposite was composed of monodisperse heterostructural Fe3O4/ZnS core and a thermo-sensitive
poly(N-isopropyl acrylamide) (PNIPAM) shell. Fe3O4/ZnS acted as magnetic response and fluorescence luminous body, PNIPAM acted as drug loaded platform which can adsorb and release drug controllably. Fe3O4/ZnS@PNIPAM was characterized and all
of the results showed that it had excellent magnetic response, photostability and thermo-sensitivity. Moreover, the drug release studies in vitro showed that the release rate increased with increasing temperature. MTT assays in model HepG2 cells demonstrated that Fe3O4/ZnS@PNIPAM
was practically non-toxic. Thus, our results revealed that Fe3O4/ZnS@PNIPAM would be used in biomedical fields such as targeted drug delivery, as well as cancer diagnosis and treatment in the nearly future.
研究领域:
生物医学工程
·
材料科学
·
药理学
✓ 已验证
DOI
高影响因子
Coatings
·
2023
·Vol. 13
·期 9
·1557
·
IF 3.4
Yan Gao,Xin Chen,Ping Xu,Jie Chen,Shihua Yu,Zhigang Liu,Xiaodan Zeng
A novel magnetic fluorescent nanoprobe (Fe3O4@ZnS@MPS(MFNPs)) was synthesized, which recognized and cooperated with Ag+ions, and a rapid method for detecting Ag+was established in solution. It was found by fluorescence spectroscopy analysis that the MFNPs could detect Ag+in PBS solution and, upon addition of Ag+ions, the fluorescence (FL) of MFNPs could be quenched significantly. The sensor has a low limit of detection (LOD) of 7.04 µM for Ag+. The results showed that MFNPs were extremely specific and sensitive for the quantitative detection of Ag+over a wide pH range. Then, the recognition mechanism between MFNPs and guest Ag+was explored via measures of infrared spectroscopy and electron microscopy. It was speculated that the oxygen atoms in the sulfonic acid group cooperated with Ag+to form a synergistic complexation. The assay was successfully used to determine the content of Ag+ in real samples.Keywords:magnetic fluorescent nanosensor;selective recognition;silver ion;3-sulfhydryl-1-propane sodium (MPS)
研究领域:
分析化学
·
纳米技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）