INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2016
·
IF 3.138
Liping Bao,Xinyi Zhu,Hongxia Dai,Yongxin Tao,Xiaoying Zhou,Wenjie Liu,Yong Kong
Mercaptosuccinic acid (MSA) molecules were inserted into potato starch, leading to the breaking of intrinsic H-bonds within macromolecular chains of starch and the formation of intermolecular H-bonds between MSA and starch, which could be verified by Fourier transform infrared spectroscopy (FT-TR). MSA modified porous starch xerogels (PSX/MSA) were obtained after freeze-drying the MSA modified starch, and they were characterized by field emission scanning electron microscopy (FESEM), exhibiting the intriguing porous structure due to the separation of starch chains by MSA molecules. The PSX/MSA were then used as the adsorbents to remove gardenia yellow (GY), a natural colorant with genotoxicity. Due to the porous structure of PSX and the introduced carboxyl groups from MSA, the adsorption capacity of the PSX/MSA was much higher than that of the starch xerogels alone (SX). The adsorption behaviors of GY by the PSX/MSA fitted both the Freundlich isotherm model and the pseudo-second-order kinetic model, and the efficient adsorption of GY suggested that the PSX/MSA might be potential adsorbents for the removal of dyes from contaminated aquatic systems.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials
·
2024
·Vol. 17
·期 8
·1921
·
IF 3.1
Yu Wang,Tao Xing,Lifeng Yan
Hydrogen is a dangerous gas as it reacts very easily with oxygen and may explode; therefore, the accumulation of hydrogen in confined spaces is a safety hazard. Composites consisting of unsaturated polymers and catalysts are a common getter, where the commonly used polymer is 1,4- diphenylethynyl benzene (DEB). Silicone rubber (SR) is a good carrier for hydrogen-absorbing materials due to its excellent chemical stability and gas permeability. In this work, polysiloxane, water, and a emulsifier are ultrasonically injected into a uniform emulsion, and the hydrogen getter DEB-Pd/C (Palladium on carbon) is then added. Under the catalysis of platinum (Pt), the cross-linking agent undergoes a hydrosilylation reaction to cross-link polysiloxane in emulsion to form silicone rubber. Then, the water was removed by freeze-drying, and the loss of water constructed a porous frame structure for silicone rubber, thus obtaining porous silicone rubber. The difference in hydrogen absorption performance between porous silicone rubber and ordinary silicone rubber was compared. It was found that, with the increase in water in the emulsion, the porous frame of silicone rubber was gradually improved, and the hydrogen absorption performance was improved by 243.4% at the highest, almost reaching the theoretical saturated hydrogen absorption capacity. Porous silicone rubber was prepared by emulsion mixing, which provided a new idea for further improving the hydrogen absorption performance of silicone rubber.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
AICHE JOURNAL
·
2015
·Vol. 61
·期 6
·2048-2057
·
IF 2.748
Wei Wang,Dapeng Hu,Yanqiu Pan,Yanqiang Zhao,Guohua Chen
To save drying time and increase productivity, a novel idea was proposed for freeze-drying of liquid materials by creating an initially unsaturated frozen structure. An experimental investigation was carried out aiming at verifying the idea using a multifunctional freeze-drying apparatus. Mannitol was selected as the primary solute in aqueous solution. Liquid nitrogen ice-cream making method was used to prepare the frozen materials with different initial porosities. Results show that freeze-drying can be significantly enhanced with the initially unsaturated frozen material, and substantial drying time can be saved compared with conventional freeze-drying of the initially saturated one. Drying time was found to decrease with the decrease in the initial saturation. The drying time for the initially unsaturated frozen sample (S 0 = 0.28 or 0.69 of initial porosity) can be at best 32% shorter than that required for the saturated one (S 0 = 1.00 or zero porosity). This unique technique is easy to implement and improves the freeze-drying performance of liquid materials. © 2015 American Institute of Chemical Engineers AIChE J , 61: 2048–2057, 2015
研究领域:
化学工程
·
制药工艺
·
干燥技术
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2014
·
IF 3.259
Fei Pei,Ying Shi,Xingyang Gao,Fangning Wu,Alfred Mugambi Mariga,Wenjian Yang,Liyan Zhao,Xinxin An,Zhihong Xin,Fangmei Yang,Qiuhui Hu
Button mushroom slices were dehydrated using freeze drying (FD) or FD combined with microwave vacuum drying (FMVD), and the non-volatile component profiles were studied. The results showed that the level of non-volatile components in button mushroom firstly increased during sublimation of FD/FMVD process and then fell during desorption in FD process and MVD in FMVD process. Compared to FD products, the contents of soluble sugars and polyols in FMVD products were relatively low, whereas the contents of total free amino acids were significantly higher, close to the level of fresh mushroom. However, there was no significant difference in the contents of 5′-nucleotides and organic acids between FD and FMVD products. The equivalent umami concentration ( EUC ) values for FD and FMVD products did not differ from fresh, indicating that both drying methods could effectively preserve MSG (monosodium glutamate)-like components in button mushroom.
研究领域:
食品科学
·
农业工程
·
化学工程
✓ 已验证
DOI
PubMed
高影响因子
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
·
2018
·Vol. 97
·期 3
·709-716
·
IF 1.265
Wei Wang,Dapeng Hu,Yanqiu Pan,Hengle Li,Guohua Chen
Initially unsaturated material frozen with prefabricated porosity was prepared to experimentally investigate its effect on freeze-drying of liquid material. Ceftriaxone sodium, a kind of commonly used antibiotic, was selected as the primary solute in an aqueous solution. The liquid nitrogen ice cream-making method was employed to prepare frozen materials with different initial porosities. Results showed that freeze-drying was significantly enhanced with the initially unsaturated frozen material and substantial drying time was saved compared with conventional freeze-drying. Drying time for the unsaturated sample (0.3 of saturation or 0.67 of initial porosity) was more than 20 % shorter than that required for the saturated one (1.0 of saturation without initial porosity). SEM images displayed that the dried products of the unsaturated frozen material had a pierced solid skeleton and uniform pore space with a fine and tenuous structure compared with those of the saturated one. The freezing rate exhibited little influence on the freeze-drying process. Annealing can be moderately beneficial to shortening the drying time and further improving the energy utilization. An appropriate increase in operating temperature was able to enhance the freeze-drying rate while changes in chamber pressure had a negligible effect on the process.
研究领域:
制药工程
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Soft Matter
·
2025
·
IF 2.8
Tongtong Zhang,Shuo Wang,Hongyu Liu,Xiaolong Yang,Fangming Zhu
A facile method has been developed to produce syndiotactic polystyrene (sPS) aerogels by only three steps of polymer dissolution, gel aging and freeze-drying without any solvent exchange, unlike typical methods for sPS aerogel preparation. Due to the high melting point of p-xylene (around 13 °C), p-xylene-based sPS gels are unexpectedly robust in allowing the formation of aerogels by direct p-xylene removal through sublimation, leading to a more efficient synthesis and better quality of aerogels with much stronger mechanical properties. Furthermore, without the interference of solvent exchange, it is more suitable to explore the influence of key parameters (sPS content and molecular weight in precursor gels) on the preparation of sPS aerogels. The content and molecular weight of sPS will affect the crystallinity and porosity of the sPS aerogels, which can further control the microstructure, mechanical properties, dielectric constant, and adsorption performance of the materials. The obtained low density sPS aerogels with 98.9% porosity exhibited a minimum dielectric constant of 1.02 at low frequencies and high adsorption capacity towards different organic solvents and common oil.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Tongtong Zhang,Shuo Wang,Hongyu Liu,Xiaolong Yang,Fangming Zhu
We have developed a strategy to synthesize high-quality ultralight (<10 mg/cm3) syndiotactic polystyrene (sPS) aerogels. The ultralight sPS aerogels with the same shape as gels were prepared via direct freeze-drying of p-xylene-based sPS gels without cumbersome solvent exchange steps. Due to the high melting point of p-xylene (13 °C), it can be solidified during the freeze-drying process, and no solvent exchanges were required to suppress the collapse during the formation of sPS aerogels, unlike in typical sPS aerogel preparation. The ultralight sPS aerogels with the highest porosity of 99.6% and the lowest density of 4.5 mg/cm3 can be easily prepared. Morphological analysis of the ultralight aerogels confirmed that the 3D fibrous network structure was formed after p-xylene sublimation. The dielectric constant of the ultralight sPS aerogels (κ = 1.01) represents the lowest value ever reported for polymer-based aerogels, closely approaching that of air. In particular, their ultralow density, ultrahigh porosity, highly hydrophobic and oleophilic properties, adequate mechanical strength, and interconnected porous fiber-like structure make them suitable adsorbents for oil and organic solvents, which are promising candidates for removing pollutants and separating oil and water. The structural and property changes of the ultralight aerogels induced by annealing above Tg of sPS were comprehensively analyzed. This simple aerogel preparation method can utilize the ultralight sPS aerogel framework as a suitable scaffold for preparing composite materials, which is conducive to enhancing the properties and extending the applications of sPS aerogels in various fields.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Pharmaceutics
·
2019
·Vol. 11
·期 10
·539
·
IF 4.773
You Xu,Yiyue Guo,Yuqi Yang,Yingying Meng,Xuejun Xia,Yuling Liu
Deformable nanovesicles have been extensively investigated due to their excellent ability to penetrate biological barriers. However, suffering from serious physical and chemical instabilities, the wide use of deformable nanovesicles in medical applications is still limited. Moreover, far less work has been done to pursue the lyophilization of deformable nanovesicles. Here, we aimed to obtain stable deformable nanovesicles via freeze-drying technology and to uncover the underlying protection mechanisms. Firstly, the density of nanovesicles before freeze-drying, the effect of different kinds of cryoprotectants, and the types of different reconstituted solvents after lyophilization were investigated in detail to obtain stable deformable nanovesicles based on insulin-phospholipid complex (IPC-DNVs). To further investigate the underlying protection mechanisms, we performed a variety of analyses. We found that deformable nanovesicles at a low density containing 8% lactose and trehalose in a ratio of 1:4 (8%-L-T) have a spherical shape, smooth surface morphology in the lyophilized state, a whorl-like structure, high entrapment efficiency, and deformability after reconstitution. Importantly, the integrity of IPC, as well as the secondary structure of insulin, were well protected. Accelerated stability studies demonstrated that 8%-L-T remained highly stable during storage for 6 months at 25 °C. Based on in vivo results, lyophilized IPC-DNVs retained their bioactivity and had good efficacy. Given the convenience of preparation and long term stability, the use of combined cryoprotectants in a proper ratio to protect stable nanovesicles indicates strong potential for industrial production.Keywords:deformable nanovesicles;combination;cryoprotectant;mechanism;insulin
研究领域:
药剂学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 15
·7491-7502
·
IF 4.682
Zhai Shengnan,Yu Kejing,Meng Chaoran,Wang Hongbo,Fu Jiajia
In this paper, an eco-friendly method of producing hybrid silica aerogels by freeze-drying method (FD) is proposed. In the freeze-drying system, deionized water was the only solvent, hybrid aerogels were prepared by acid–base catalysis and sol–gel method using methyltrimethoxysilane (MTMS) and water–glass as co-precursors. The microstructure, specific surface area, pore size distribution and thermal properties of the hybrid aerogels were characterized and analyzed. It was found that all samples exhibited the dual-mesoporous structures, and the molar ratio of co-precursors had a significant effect on the performance of aerogels. The tap density decreased and the porosity increased with the increase in the molar ratio of MTMS, while the thermal diffusion coefficient and thermal conductivity of aerogel decreased first and then increased. Especially when the molar ratio is 2.0, the hybrid aerogels exhibited excellent insulation performance, such as thermal diffusion coefficient of 0.0183 mm s −1 , thermal conductivity of 0.0460 W(m k) −1 and great thermal stability up to 540 °C. It illustrates that hybrid aerogels have broad application prospects as insulation materials.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
CELLULOSE
·
2018
·Vol. 26
·期 3
·1747-1755
·
IF 3.809
Zhou Ting,Cheng Xudong,Pan Yuelei,Li Congcong,Gong Lunlun
Abstract Polyvinyl alcohol (PVA)/cellulose nanofibers (CNFs)/Gelatin hybrid organic aerogels were synthesized using a facile and environmentally friendly freeze-drying method. The biobased gelatin acted as a cross-linking agent and combined PVA and CNFs tightly by hydrogen bonds. The composites were characterized and analyzed by various techniques including uniaxial compression test, scanning electron microscopy, as well as thermal conductivity analysis and TGA–DTG analyses. The mechanical properties were strengthened significantly with the introduction of a small amount of gelatin. The modulus of PVA/CNF/G3 was 1.65 MPa, nearly eightfold of the PVA/CNF aerogel and 91 times higher than the neat CNF aerogel. Microstructure analyses revealed the three-dimensional network of the aerogels. The composites also possess good thermal stability, low density, and low thermal conductivity. Therefore they have broad prospects in the field of thermal insulation. Graphical abstract
研究领域:
材料科学
·
生物材料
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yize Yin,Wenchao Liu,Linlin Li,Weiwei Cao,Junliang Chen,Linlin Zhao,Xiaofei Sun,Xu Duan,Guangyue Ren
This article investigates the effect of different microwave powers on the crosslinking behavior and microwave freeze-drying characteristics of wheat starch-lauroyl arginate complex during the microwave freeze-drying process. During microwave freeze-drying, as microwave power increased from 0.1 W/g to 0.9 W/g, the freeze-drying time of WS-LA was reduced by 50 %, while the uniformity of freeze-drying was not affected by its composition. In the research results obtained from DSC, Raman spectroscopy, Fourier-transform infrared spectroscopy (FTIR), XRD, and SEM analyses, with the microwave power increased from 0.1 W/g to 0.9 W/g, the enthalpy value of the melting peak of the WS-LA (wheat starch-lauric acid) composite decreased from 1.15 J/g to 0.62 J/g. The full width at half maximum (FWHM) value increased from 25.6 to 30.79. The ratio of absorbance at 1022/995 cm −1 increased from 1.0111 to 1.0707. The recrystallization (RC) value decreased from 8.77 % to 0.07 %. Additionally, in the microstructure, the size of WS-LA composite particles decreased accordingly. The above findings indicated that the increase in microwave power during microwave freeze-drying had a negative impact on the formation of the WS-LA complex and the ordering of its structure in the sample.
研究领域:
食品科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Tong Zhang,Chen Wang,Shengpeng Su,Axiang Sun,Ting Du,Jianlong Wang,Julong Liu,Wentao Zhang
Probiotic powder using a single protective method during freeze-drying is insufficient vitality because it lacks adequate protection. Here we developed a protection strategy through biointerfacial phenolic self-assembly to enhance the protection of excipients for probiotics to address existing challenges during freeze-drying. This strategy could strengthen the connections of excipients and phenolic protective layers containing hydroxyl groups with water molecules, improving the hydration layer's preservation and shielding bacteria from damage. The results indicated that, compared with origin probiotics, protected probiotics maintained higher viability at approximately 91 % and higher ATPase activity and exhibited a better survival rate in various environmental challenges after freeze-drying. The broad applicability of this protection strategy was confirmed across other LAB strains. Additionally, the protected probiotics demonstrated superior shelf life during 30 days of storage, indicating promising prospects for preparing bacterial powder via freeze-drying.
研究领域:
微生物学
·
食品科学
·
生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）