International Journal of Polymeric Materials and Polymeric Biomaterials
·
2023
·
IF 3.2
Jiashuo Liu,Runzhi Xiang,Hongtao Li,Hong Zhu,Jiarui Dang,Zhihui Ran,Huan Deng,Wenjin Xu,Chengjie Xiong,Zhijun Huang,Peihu Xu,Haixing Xu
Here, a novel kind of composite scaffold was fabricated by loading vascular endothelial growth factor (VEGF) and gastrodin liposome (GAS-LP) into electrospun silk fibroin/graphene oxide(SF/GO)nanofibrous and silk fibroin sponge-filled, respectively. Our results demonstrated that VEGF and GAS exhibited different release patterns in vitro which VEGF showed rapid release rate in the first few days while GAS was released slowly and continuously as encapsulated in liposomes. The scaffolds realized the combination of intraneural vascularization drugs and electrical stimulation effectively, leading to enhanced growth of RSC96 cells. Furthermore, the scaffolds could protect RSC96 cells in an inflammatory environment.
研究领域:
生物材料
·
组织工程
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神经科学
·
药物递送系统
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产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2023
·
IF 2.5
Liu Wenjun,Guan Jinyu,Kong Bo,Lu Hongbing,Wu Yu,Qin XiaoLi,Jiang Hongmei,Liu Xiaoying
The severe toxicity of heavy metal ions (HMIs) to both the environment safety and human health makes it challenging to build a system that can simultaneously detect them. A method simultaneous electrochemical detection of Cd 2+ and Pb 2+ was developed here using amino-functionalized bismuth-based metal–organic frameworks (NH 2 -Bi-MOFs) and graphene aerogels (GAs) composites. The GAs/NH 2 -Bi-MOFs composites were made by ultrasonically depositing the NH 2 -Bi-MOF on the GAs. GAs support NH 2 -Bi-MOFs and boost their conductivity by accelerating electron transmission through the matrix. NH 2 -Bi-MOFs acted as a binding site for Cd 2+ and Pb 2+ , because hydrophilic groups (-NH 2 ) and bismuth metal active sites collaborated. The GAs/NH 2 -Bi-MOFs composite–modified electrodes detection capability was assessed. The proposed electrochemical sensor can be effectively used for individual and simultaneous detection of the Cd 2+ and Pb 2+ in aqueous solutions with outstanding sensitivity and interference used to simultaneously detect Cd 2+ and Pb 2+ in river water and tap water samples with satisfactory accuracy and repeatability. This paper provides a unique technique for concurrently detecting Cd 2+ and Pb 2+ in practical applications.
研究领域:
环境科学
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材料科学
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分析化学
·
电化学
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产品关联
DOI
高影响因子
Journal of Functional Foods
·
2024
·
IF 3.8
Xiaotian Xu,Xinhui Li,Xingshu Wei,Xiaoqun Duan,Yuhui Wang
Passion fruit peel fermentation extract (PFPFE) increased gastrointestinal transport power and fecal moisture content, protected the structural integrity of colon tissue, and reduced inflammatory infiltration. PFPFE also increased secretion of the ET-1, GAS, MTL, and SP, and decreased secretion of the inhibitory SS and VIP. In addition, PFPFE alleviated perirectal redness and hemorrhage in hemorrhoid mice, and downregulated levels of the serum inflammatory factors tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β). In this study, we also analyzed the main active components and core targets of PFPFE for alleviating constipation and hemorrhoids through network pharmacology, and predicted its mechanism of action. Finally, we carried out Western blot experiments to verify that PFPFE and its active component kae alleviates constipation and hemorrhoids in mice by downregulating ESR1 and PI3K/Akt pathways. These results provide a scientific basis for the development of PFPFE as a functional food for alleviating constipation and hemorrhoids.
研究领域:
药理学
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胃肠病学
·
分子生物学
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DOI
高影响因子
Petroleum Science
·
2026
·
IF 6.4
Zhen-Bin Xu,Yi-Wei Wu,Hong-Nan Chen,Hong-Shuai Wang,Yu-Hao Bu,Xiao-Hui Wang,Chang-Yu Sun,Guang-Jin Chen
The commercial-scale development of natural gas hydrates is constrained by low single-well productivity and short production duration, making it difficult to achieve economic viability. Based on the accumulation features of the hydrate-bearing layer (HBL), shallow gas layer (SGL) and deep gas layer (DGL), the three-gas co-production is expected to promote the commercial development of marine hydrates by substantially increasing total gas production. A new reservoir preparation method that explicitly accounts for the geothermal gradient is proposed. The effects of well position and mining pressure on pressure response, the evolution of temperature field and gas/water production were systematically studied. The results show that placing the mining well beneath the SGL improves production efficiency, but it will sacrifice the thermal energy available from the shallow and deep gas. Reducing the mining pressure, particularly below the quadruple point, enhances gas production but introduces safety risks, including excessive pressure differences, icing, and hydrate re-formation. A multi-stage depressurization strategy effectively mitigates these issues, reducing the maximum pressure difference by 32% and increasing the average minimum temperature by 1.71 °C. Further optimization is possible by adjusting the depressurization stages and duration. This study expands the understanding of joint production characteristics for formulating mining strategies.
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Tianjun Hu,Yaru Chen,Ying Wang,Mengtian Kang,Jiale Li,Junming Zhang,Ergui Luo,Jianfeng Jia
Amorphous metal oxides offer unique advantages for gas sensing due to their disordered structures and abundant defects, yet their potential for Triethylamine (TEA) detection remains underexplored. This study investigates the gas sensing performance of amorphous and crystalline Fe 2 O 3 for TEA detection, aiming to explore the potential of amorphous Fe 2 O 3 as a superior alternative to traditional crystalline Metal Oxide Semiconductors (MOS). The structural and morphological characteristics of the samples were analyzed, revealing that amorphous Fe 2 O 3 possesses a higher specific surface area and a disordered structure with abundant oxygen vacancies. The gas sensing tests showed that the amorphous Fe 2 O 3 sensor exhibited higher sensitivity, selectivity, and faster response/recovery times compared to the crystalline Fe 2 O 3 sensor. These findings suggest that amorphous Fe 2 O 3 could be a promising material for developing highly sensitive, selective, and energy-efficient TEA gas sensors.
研究领域:
材料科学
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化学传感器
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纳米技术
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Jiashang Chen,Jin Huang,Hui Fang,Hemi Qu
Colorimetric gas sensors show promise as selective detectors for gas chromatography (GC), but their application has been limited by the irreversibility of their responses. This study presents the successful hyphenation of colorimetric gas sensors with GC, overcoming this limitation through a novel approach that refreshes the sensor’s reaction area with controlled movement, enabling the generation of reversible GC peaks. The sensors, based on acid–base indicators, such as chlorophenol red and bromocresol green, were integrated with a capillary GC column and evaluated for amine detection. Performance testing revealed satisfactory sensitivity, linearity, and reproducibility, with the colorimetric sensors demonstrating superior selectivity for amines compared to flame ionization detectors (FID). Moreover, a dual-sensor array, combined with a pattern recognition algorithm, enabled effective discrimination between various amine compounds. This work establishes a promising, cost-effective alternative for portable GC systems, enhancing selectivity and improving the capability of field vapor analysis.
CAS / MDL:
研究领域:
分析化学
·
传感器技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2023
·
IF 4.2
Xing-Ya Ni,Xiao-Fang Lv,Rong-Qiang Zhong,Yang Liu,Chuan-Shuo Wang,Qian-Li Ma,Yan-Yun Xiao,Shi-Dong Zhou,Shang-Fei Song
The mixed gas separation of hydrate technology can promote biogas separation, purify CO2, and improve the quality of CH4 while reducing carbon emissions and realizing efficient CO2 capture and storage. Herein, we identified the effects of low-content 1,3-dioxolane (DIOX) on the separation efficiency and kinetics of a CH4/CO2 (6:4) mixture via gas hydrates. The experimental results showed that the hydrate formation with DIOX had five stages. The purification rate of CH4 could be effectively accelerated with the increase in DIOX concentrations. At 4.5 MPa and 274.65 K, the induction time of hydrate formation could be reduced by 93.3% compared to that of the pure water system. However, higher driving forces could lead to dense hydrate film and reduce the separation efficiency of CO2/CH4. The suitable pressure and temperature (e.g., 4 MPa, 274.65 K) could alleviate this problem, and it could result in a CO2 recovery of 92.2%. When the gas–liquid ratio was 3.5, the CO2 recovery could be increased by 23% and the CO2 phase equilibrium constant could be increased by 2.8 times compared to that of the pure water system.
研究领域:
化学工程
·
环境科学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
·
2019
·
IF 4.346
Hao Feng,Xun Zhu,Rong Chen,Qiang Liao
In this work, the gas consumption characteristics were investigated by gas-liquid two-phase flow in a capillary microreactor using the catalytic hydrogenation of nitrobenzene as a reference gas-liquid reaction. Image processing technique was used to measure the gas consumption from the variation in the gas phase through the recorded images. The influence of the inlet nitrobenzene concentration and both the gas and liquid flow rates on the gas consumption and the microreactor performance was investigated. The experimental results showed that there existed a discrete hydrogen consumption process, i.e. the waiting stage and inburst stage. Hydrogen consumption was mainly attributed to the waiting stage in each bubble formation cycle. Minimal hydrogen was consumed in the inburst stage. In addition, there was a clear difference between the H 2 consumption rates under each operating condition. As the gas flow rate and nitrobenzene concentration increased, the H 2 consumption rate was gradually decreased with each successive formation cycle. Although the consumption rate was gradually reduced with each successive formation cycle with increasing liquid flow rate, the downward trend became increasingly gradual and clearly stabilized at 20 μL/min. The microreactor performances under different operating conditions were also investigated. The results showed that the nitrobenzene conversion was first increased and then gradually decreased with increasing the gas flow rate, whereas it was gradually decreased with increasing both the liquid flow rate and nitrobenzene concentration. The results obtained in this work are beneficial for not only understanding process intensification but also promoting the use of microreactor technology in additional industrial applications.
研究领域:
化学工程
·
催化反应
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产品关联
DOI
高影响因子
ACS Nano
·
2024
·
IF 15.8
Lu Li,Yuliang Li,Ke Li,Wentao Zou,Honghao Li,Yan Li,Linyang Li,Qiuya Zhang,Chunyu Zhang,Xiaofang Zhang,Dongliang Tian,Lei Jiang
Electrocatalytic nitrogen reduction reaction (NRR) is a very attractive strategy for ammonia synthesis due to its energy savings and sustainability. However, the ammonia yield and Faraday efficiency of electrocatalytic nitrogen reduction have been challenges due to low nitrogen solubility and competitive hydrogen evolution reaction (HER) in electrolyte solution. Herein, inspired by the asymmetric wetting behavior, i.e., superhydrophobicity/hydrophilicity, of floating lotus leaves, we demonstrated a gas-conduction electrode with asymmetric gas wetting behavior on the opposite surface, i.e., Janus-Ni/MoO2@NF, for efficient nitrogen reduction. It can provide an abundant three-phase interface (TPI) at interfaces of Janus-Ni/MoO2@NF in electrolyte solution to enhance the contact among N2, electrolyte, and electrode. Ascribed to this advantage, the hydrophobic side of the Janus electrode not only can repel water molecules to suppress the HER process but also can increase the concentration of N2 on the interface microenvironment. Consequently, the well-designed gas-conducting electrode breaks gas mass transfer limitation. Furthermore, Janus-Ni/MoO2@NF delivers a record-high NH3 yield rate of 5.865 μg·h–1·cm–2 and a Faradaic efficiency of 36.14% at an extremely low potential of 0 V vs RHE in 0.1 M Na2SO4 under ambient conditions, which are 22 and 18 times higher than those of the conventional electrode, respectively. Therefore, the gas-conducting electrodes can dramatically improve the activity and selectivity in electrocatalytic NRR. Additionally, the unique interface design provides inspiration for other sustainable electrochemical reactions involving gas electrocatalytic correlation.
研究领域:
化学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2026
·Vol. 31
·期 9
·1486
·
IF 5.1
Yiwei Wang,Lina Meng,Zheng Liu,Shiguang Fan,Jinqiang Liang,Zhen Xu,Qiang Sun,Xuqiang Guo
As a finite strategic resource, helium is extracted from natural gas (NG). The concentration of helium in NG is very low, which makes helium hard to separate. The hydrate-based gas separation (HBGS) was proposed as a promising method for the separation of the NG with low helium content in this work. This work systematically investigated the HBGS of helium from simulated NG. The thermodynamic analysis reveals that the existence of 5.00 mol% tetrahydrofuran (THF) in the liquid phase decreased the gas–liquid–hydrate equilibrium pressure by 92.11%, compared to the deionized water system. The single-stage HBGS experimental results show that high THF concentration, low temperature, and high pressure benefited the gas processing capacity and helium purification, but they led to a low helium recovery rate. The best HBGS performance was limited by the “hydrate shell effect”. The decrease in gas–liquid ratio led to an increase in helium concentration without losing the gas processing capacity, but it caused a decrease in the helium recovery rate. Through three-stage HBGS optimization, the helium concentration was increased from 0.54 mol% to 13.54 mol% (a 25.07-fold enrichment), and a total helium recovery of 87.34% was achieved. The mathematical model proposed in this work accurately predicts the performance of HGBS with 2.09% average relative error compared to the experimental data.
✓ 已验证
DOI
PubMed
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Yongtao Zhang,Zaizheng Jiang,Zhihe Xin,Qingqi Dong,Fei Wang
Traditional coal burning emits a large amount of pollutants, including sulfur dioxide (SO2), nitrogen oxides, and carbon dioxide (CO2), severely contaminating the environment and exacerbating global warming. In contrast, integrated gasification combined cycle (IGCC) technology, with highly efficient and clean characteristics, significantly reduces pollutant emissions and has a positive impact on environmental protection. It is a simple and effective method to obtain hydrogen (H2) by purifying IGCC fuel gas with the main components of H2 and CO2. Thermodynamic promoter tetra-n-butyl ammonium bromide (TBAB) is widely used in gas separation of IGCC fuel gas by the hydrate method. In this work, polystyrene nanoparticles grafted by –SO3– groups (−SO3–@PSNS) and grafted by –SO3– groups and Ag particles (Ag&–SO3–@PSNS) are used together with TBAB, respectively, to promote the formation of hydrate. The gas separation effect and growth morphology are studied. The experimental results demonstrate that the incorporation of nanopolymer can significantly enhance the separation efficiency (SFr) of a mixture of H2 and CO2. Notably, compared to the reaction solution without nanopolymer, 2 mmol/L –SO3–@PSNS exhibits the most pronounced effect on gas separation, resulting in an impressive gas consumption of 0.755 ± 0.323 mmol/L and a remarkable increase in the separation factor (SF) by 106%. After loading silver nanoparticles, the promoting effect of Ag&–SO3–@PSNS is further strengthened. Under Ag&–SO3–@PSNS-20%, the gas consumption reaches the maximum of 0.775 ± 0.003. Under Ag&–SO3–@PSNS-30%, the SF rises from 32.79 ± 6.27 to 37.92 ± 7.19, indicating an impressive increment of 15.80%. The visualized droplet experiment shows that Ag&–SO3–@PSNS significantly promotes the nucleation of hydrate and the growth rate of hydrate.
研究领域:
能源与燃料
·
环境科学
·
化学工程
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2020
·Vol. 10
·期 6
·
IF 4.324
Fang Peng,Yan Sun,Weiwei Yu,Yue Lu,Jiaming Hao,Rui Cong,Jichao Shi,Meiying Ge,Ning Dai
In this work, the compositional optimization in copper oxide/tungsten trioxide (CuO/WO3) composites was systematically studied for hydrogen sulfide (H2S) sensing. The response of CuO/WO3composites changes fromp-type ton-type as the CuO content decreases. Furthermore, thep-type response weakens while then-type response strengthens as the Cu/W molar ratio decreases from 1:0 to 1:10. The optimal Cu/W molar ratio is 1:10, at which the sensor presents the ultrahighn-type response of 1.19 × 105to 20 ppm H2S gas at 40 °C. Once the temperature rises from 40 °C to 250 °C, the CuO/WO3(1:1) sensor presents thep-nresponse transformation, and the CuO/WO3(1:1.5) sensor changes from no response ton-type response, because the increased temperature facilitates the Cu-S bonds break and weakens thep-type CuO contribution to the total response, such that the CuS bond decomposition by a thermal effect was verified by a Raman analysis. In addition, with a decrease in CuO content, the CuO is transformed from partly to completely converting to CuS, causing the resistance of CuO to decrease from increasing and, hence, a weakening mode ofp-CuO andn-WO3to the total response turns to a synergistic mode to it.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）