MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Tian Si-Yu,Ding Zhu,Yao Mu-Lan,Liu Si-Mian,Hou Xiang-Yang,Tang Long,Yue Er-Lin,Wang Xiao,Wang Ji-Jiang
A three-dimensional UiO-67-BDA with various pore structures and abundant active binding sites is constructed, and Fe@UiO-67-BDA composites with electrochemical sensing and recognition performance were further prepared by successfully loading Fe 3+ ions. The different modified electrodes (Fe@UiO-67-BDA/GCE, UiO-67-BDA/GCE, Fe/GCE) and the bare electrode (GCE) were also characterized in terms of basic structure and electrochemistry, and it was found that the basic structure and electrochemical performances of Fe@UiO-67-BDA/GCE were better than those of the remaining three electrodes, with good selectivity, reproducibility and stability. And the Fe@UiO-67-BDA/GCE sensor with good electrochemical performance was constructed under the optimal working potential (E pa = 0.59 V) and experimental conditions, which was utilized to rapidly and accurately detect heavy metal ions Hg 2+ by the DPV method, with a detection limit of up to 1.642 × 10 −9 M. In addition, the electrochemical behavior mechanism of the Fe@UiO-67- BDA/GCE sensor was investigated. Finally, the sensor was applied to detect cosmetic heavy metal ions, and the experimental results also showed high reliability and practicality. Therefore, MOFs composite material is applied to the field of electrochemistry, because of its simple operation technology, fast detection speed and high sensitivity, so that it has a greater application prospect.
研究领域:
分析化学
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环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Materials
·
2019
·Vol. 12
·期 21
·3637
·
IF 2.972
Runqiang Liu,Yashuang Wang,Bo Li,Binbin Liu,Huina Ma,Dongdong Li,Li Dong,Fang Li,Xiling Chen,Xinming Yin
In this work, a carbon black (VXC-72R)/zirconia (ZrO2) nanocomposite-modified glassy carbon electrode (GCE) was designed, and a VXC-72R/ZrO2/GCE-based electrochemical sensor was successfully fabricated for the high-sensitivity detection of methyl parathion (MP). Electrochemical measurements showed that the VXC-72R/ZrO2/GCE-based electrochemical sensor could make full use of the respective advantages of the VXC-72R and ZrO2nanoparticles to enhance the MP determination performance. The VXC-72R nanoparticles had high electrical conductivity and a large surface area, and the ZrO2nanoparticles possessed a strong affinity to phosphorus groups, which could achieve good organophosphorus adsorption. On the basis of the synergistic effect generated from the interaction between the VXC-72R and ZrO2nanoparticles, the VXC-72R/ZrO2/GCE-based electrochemical sensor could show excellent trace analysis determination performance. The low detection limit could reach up to 0.053 μM, and there was a linear concentration range of 1 μM to 100 μM. Such a high performance indicates that the VXC-72R/ZrO2/GCE-based electrochemical sensor has potential in numerous foreground applications.Keywords:VXC-72R/ZrO2/GCE nanocomposite electrode;synergetic effect;electrochemical sensor;methyl parathion
研究领域:
分析化学
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环境科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS RESEARCH
·
2024
·
IF 2.7
Qiao Xinxin,Bian Ruihan,Li Shu,Zhu Jialei,Wang Fuqin,Liu Chang
In the paper, a high-performance electrode was reported for the determination of uric acid (UA) and dopamine (DA) by loading nanocomposites Fe 2 O 3 /poly-neutral red (PNR)/partially reduced graphene oxide (rGO) on glassy carbon electrode (GCE). The nanocomposites Fe 2 O 3 /PNR/rGO were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectrometer (FTIR), and electrochemical impedance spectroscopy (EIS). Under the optimized condition, the peak currents of UA and DA showed good linear relationships with their concentrations in the range of 1 × 10 –6 to 1 × 10 –3 mol L −1 and 3 × 10 –7 to 9 × 10 –5 mol L −1 , respectively. The recovery rates were 93.0–102.0% and 99.2–104.6% for detecting DA from medical injections and human specimens, including urine and serum, respectively, 95.5–105.0% for UA from urine and serum samples. Obviously, this Fe 2 O 3 /PNR/rGO/GCE is expected to be used in production quality control and clinical test. Graphical abstract
研究领域:
分析化学
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生物医学工程
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
·
IF 5.4
Ruixue Yan,Hao Guo,Zeyun Yang,Wenting Niu,Jianpeng Ma,Liping Peng,Mingyue Wang,Wu Yang
Alterations in guanine (GA) and adenine (AE) levels within the human body are intricately linked to overall health and daily physiological functions. Therefore, it is crucial to develop an accurate and sensitive sensor for quantifying the levels of GA and AE. In this present paper, a novel electrochemical sensor NH 2 -MXene@COF TA-DH /GCE was constructed by in-situ growing COF TA-DH with high crystallinity, good thermal stability and N-rich active centers based on Schiff base condensation reaction of 1, 3, 5-tris-(4-aminophenyl) triazine (TAPT) and 2,5-dihydroxyl-terephthalaldehyde (DHTA) on highly conductive NH 2 -MXene and then modifying it on the surface of the glass carbon electrode (GCE). The highly dispersed sandwich structure of NH 2 -MXene@COF TA-DH significantly increases the specific surface area and exposes a greater number of active sites. Benefitted from remarkable synergistic effect, the sensor exhibited excellent electrochemical catalytic activity and high sensitivity for GA and AE detection. The sensing platform was successfully used for simultaneous detection of GA and AE with wide linear ranges of 0.6–230 μM and 1–450 μM and low detection limits of 0.07 μM and 0.44 μM, respectively. This study expands applications of COFs and MXene in electrochemical biosensing platform and provides a general and valuable strategy for COFs-based electrochemical sensor construction for biomedical investigations
研究领域:
生物医学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2022
·Vol. 169
·期 9
·097508
·
IF 4.386
Xiaomin Guo,Pinghua Chen,Hualin Jiang,Xiaoqiu Tang,Yiping Huang,Guanghui Wu,Jian Zhang
Due to the strong toxicity of heavy metal ions to public health and the environment, it is a great challenge to develop a method for ultra sensitive capture and determination of heavy metal ions effectively. Herein, a novel heterostructure composite (MIL-53(Fe)/Ag2CrO4, named MA(1:x)) was prepared by a simple method successfully. MA(1:x) modified GCE was applied to detect heavy metals ions simultaneously. Significantly, the designed MA(1:1)/GCE sensors performed outstanding detection performances. The wide ranges of 7.49 ∼ 320.00 μmol l−1 and 7.49 ∼ 320.04 μmol l−1 are obtained for Pb(II) and Cu(II) ions, respectively. The LOD of the MA(1:1)/GCE sensor was determined to be 27.40 nmol l−1 (5.68 ppb) for Pb(II) and 86.96 nmol l−1 (5.52 ppb) for Cu(II) ion simultaneously, which are lower than the allowable level of drinking water stipulated by the World Health Organization (WHO). Possible detection mechanism by the MA(1:1)/GCE was discussed. The MA(1:1)/GCE was successfully applied to monitor heavy metal ions locate in tap and river water. The recoveries are in the range of 93.86%–104.4%, which further proves the potential in analyzing real samples. Moreover, the MA(1:1)/GCE also showed excellent stability, selectivity, reproducibility. A novel method was provided to construct sensitive sensors for simultaneous analysis of different metal ions.
研究领域:
环境科学
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分析化学
✓ 已验证
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Saijin Wang,Huiting Mao,Meng Wang,Ximing Cui,Ye Li,Yuxin Cao,Jiazheng Jin,Shi Zhou,Jinlian Li,Guogang Shan
Abnormal purine metabolism can result in oxidative stress and endothelial dysfunction, heightening the risks for conditions such as gout and cardiovascular disorders, which may subsequently trigger various physiological dysfunctions. Thus, the rapid and sensitive detection of metabolic abnormalities in purines is crucial for the early diagnosis and prevention of related diseases. Zebrafish has emerged as a popular model organism in metabolic, genetic, and toxicological studies due to its high genetic similarity to humans and the transparency of its embryos, facilitating observation. In this study, we developed a novel electrochemical sensor based on m OMe-Ir-PI/MWCNTs@PDA/GCE to detect purine molecules sensitively. Using this method, we analyzed the electrochemical behavior of zebrafish embryos, correlating the electrochemical signals with X/G and HX/A. Investigating purine metabolism in zebrafish embryos across different developmental stages, we found that from the cleavage stage to the somite formation stage, the activity of degrading enzymes increased, leading to enhanced purine oxidative degradation and the activation of metabolic pathways. This resulted in a decline in purine content, observed as decreasing electrochemical signals. Conversely, from the somite formation stage to hatching, cell differentiation, tissue formation, and organ development accelerated, leading to an increase in purines involved in energy metabolism and biosynthesis, which was reflected in rising electrochemical signals. This study represents the first application of electrochemical methods for detecting purine metabolism in zebrafish embryos throughout various developmental stages, thus providing insights into the role of purine metabolism in early life development.
研究领域:
生物化学
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分析化学
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发育生物学
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电化学
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分子生物学
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毒理学
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遗传学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Gangfeng Li,Shaobiao Feng,Lili Yan,Lijuan Yang,Bei Huo,Liuliu Wang,Sheng Luo,Dexin Yang
Due to a small amount of Cu (Ⅱ) ions being beneficial and too much being harmful, it is necessary to establish a rapid and direct detection method. Herein, we reported a platform based on multiwalled carbon nanotubes (MWCNTs), 1-butyl-3-methylimidazolium hexafluorophosphate (BMIMPF6), and Nafion solution-modified glassy carbon electrode (GCE) for the direct electrochemical detection of Cu (II) ions. We used differential pulse anodic stripping voltammetry, including the electrodeposition of Cu (Ⅱ) ions on the modified GCE and subsequent anodic stripping. Under the optimum conditions, the linear range was 20 μg·L −1 ∼ 950 μg·L −1 , the limit of detection (LOD) was 16 μg·L −1 , and the limit of quantification (LOQ) was 54 μg·L −1 for Cu (II). We realized the quantitative detection of Cu (Ⅱ) ions in juice and tea beverage without tedious pretreatment. The result showed that the sensor had good anti-interference and practicability for actual food samples.
研究领域:
分析化学
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电化学
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食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 4
·707
·
IF 5.3
Lazhen Shen,Jinlong Dong,Bin Wen,Xiangping Wen,Jianhui Li
Acetaminophen (AC) is one of the most popular pharmacologically active substances used as an analgesic and antipyretic drug. Herein, a new type of hollow Fe3O4-rGO/GCE electrode was prepared for electrochemical detection of AC through a three-step approach involving a solvothermal method for the synthesis of hollow Fe3O4and the chemical reduction of graphene oxide (GO) for reduced graphene oxide (rGO) and Fe3O4-rGO nanocomposites modified on the glassy carbon electrode (GCE) surface. The as-prepared Fe3O4-rGO nanocomposites were characterized using a transmission electron microscope (TEM), X-ray diffraction (XRD), and a magnetic measurement system (SQUID-VSM). The magnetic Fe3O4-rGO/GCE electrodes were employed for the electrochemical detection of AC using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and square wave voltammetry (SWV) and exhibited an ultra-high selectivity and accuracy, a low detection limit of 0.11 µmol/L with a wider linear range from 5 × 10−7to 10−4mol/L, and high recovery between 100.52% and 101.43%. The obtained Fe3O4-rGO-modified GCE displays great practical significance for the detection of AC in drug analysis.Keywords:acetaminophen;electrochemical detection;hollow Fe3O4nanoparticles;magnetic Fe3O4-rGO/GCE electrode
研究领域:
分析化学
·
纳米材料
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电化学
·
药物分析
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 9
·1571
·
IF 5.3
Xamxikamar Mamat,Haji Akber Aisa,Longyi Chen
Acetaminophen (N-acetyl-p-aminophenol, APAP) is regularly used for antipyretic and analgesic purposes. Overdose or long-term exposure to APAP could lead to liver damage and hepatotoxicity. In this study, the approach of enhanced electrochemical detection of APAP by nanostructured biomass carbon/silver was developed. Porous biomass carbon derived from Elaeagnus Angustifolia gum was prepared by pyrolysis with co-doping of electron-rich elements of nitrogen, sulfur, and phosphorus. The electrodeposition of silver onto a glassy carbon electrode modified with porous carbon could enhance the sensing signal towards APAP. Two linear ranges from 61 nM to 500 μM were achieved with a limit of detection of 33 nM. The developed GCE sensor has good anti-interference, stability, reproducibility, and human urine sample analysis performance. The silver-enhanced biomass carbon GCE sensor extends the application of biomass carbon, and its facile preparation approach could be used in constructing disposable sensing chips in the future.Keywords:acetaminophen;nanostructured porous carbon;electrodeposition;silver enhancement;modified GCE;electrochemical sensing
研究领域:
电化学
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材料科学
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生物质工程
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Electrochemical Science
·
2023
·
IF 1.5
Liang Bai
Salbutamol, clenbuterol, ractopamine and albuterol have the effect of promoting protein synthesis and increasing muscle mass. Despite that these substances are banned or restricted in animal husbandry in many countries, some farmers still use them illegally to improve profits. Athletes can test positive for stimulants after ingesting food with these drug residues. In this study, the electrochemical behavior of salbutamol, clenbuterol, ractopamine and albuterol were investigated with carbon nanotubes modified glassy carbon electrodes. The linear detection range and detection limit of four stimulants were studied under optimal conditions.
研究领域:
分析化学
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药物检测
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食品安全
✓ 已验证
DOI
高影响因子
Nanomaterials
·
2020
·Vol. 10
·期 1
·125
·
IF 4.324
Quanguo He,Jun Liu,Jinxia Feng,Yiyong Wu,Yaling Tian,Guangli Li,Dongchu Chen
In this paper, an electrochemical method for the measurement of tryptophan (Trp) was developed based on a glassy carbon electrode modified with polyvinylpyrrolidonefunctionalized graphene (PVP-GR)/glassy carbon electrode (GCE). In 0.1 M phosphate buffer solution (PBS, pH = 2.2), compared with bare GCE, PVP/GCE, and GR/GCE, the oxidation peak current of Trp increased dramatically at PVP-GR/GCE. The oxidation mechanism of Trp on the PVP-GR/GCE was discussed and the experimental conditions were optimized. Under the best experimental conditions, the oxidation peak current of Trp was proportional to its concentration in the range of 0.06 µM–10.0 µM and 10.0–100.0 µM, and the limit of detection (LOD) was 0.01 µM (S/N = 3). The target modified electrode with excellent repeatability, stability and selectivity, was successfully applied to detectTrp in drugs and biological samples.
研究领域:
分析化学
·
生物医学工程
·
电化学传感器
✓ 已验证
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2025
·
IF 3.3
Yirong Ma,Min Gong,Xinran Wei,Fan Yang,Yunzhe Li,Guanjun Nan,Zhimin Luo,Aiguo Zeng
A two-step electropolymerization strategy was constructed to establish an electrochemical sensor method for sensitive and selective detection of betamethasone. First, a poly-(2-aminoterephthalic acid) (P(ATA)) layer, which can significantly enhance electronic conductivity, was synthesized on the surface of the bare electrode using electropolymerization. Subsequently, taurine (Tau), which is rich in sulphonate groups, was electropolymerized and introduced into the P(ATA) layer to obtain P(Tau)/P(ATA)/GCE. Then, the electropolymerization parameters and test conditions were optimized, including the concentration of polymerization solution, the scanning rate, the polymerization cycles, buffer pH and accumulation time. Characterization of the obtained electrodes done using scanning electron microscopy and several electrochemical characterization methods proved the successful preparation of the P(Tau)/P(ATA)/GCE. Electrochemical tests of betamethasone at different concentrations (0.2-25μg·mL-1) under optimal measurement conditions exhibited excellent linearity, good sensitivity. Compared with commonly employed HPLC method, the proposed sensor method was much fast, simple, environmentally friendly, and cost-effective. Compared with other sensor methods, P(Tau)/P(ATA)/GCE sensor exhibited good sensitivity and excellent stability. Moreover, the P(Tau)/P(ATA)/GCE sensor was successfully applied to quantitatively detect betamethasone in cosmetics, which provides a new method for the monitoring of illegal addition of glucocorticoids in cosmetics.
研究领域:
分析化学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）