CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2019
·
IF 1.911
Zheng Zhang,Yuanhui Ji,Wei Chen
In this work, hollow manganese dioxide/gold nanoparticle (MnO 2 /GNPs) hybrid drug nanocarriers were prepared by coupling the gold nanoparticles (GNPs) with hollow structure manganese dioxide (MnO 2 ). Among them, GNPs have been used as near-infrared (NIR)-responsive element for photothermal effect under NIR laser irradiation. The glutathione (GSH)-responsive and pH-responsive performances of drug release were derived from hollow MnO 2 . Particularly, Doxorubicin hydrochloride (DOX) can be loaded into hollow MnO 2 /GNPs with the drug loading efficiency up to 82.0%. Moreover, the photothermal effect and GSH-/pH-responsive properties of hollow MnO 2 /GNPs were investigated. The hollow MnO 2 /GNPs possessed satisfactory drug release efficiency ( ca. 87.4% of loaded drug released in 12 h) and have high photothermal conversion efficiency, multiresponsive properties, and degradability. Finally, the kinetics of drug release was discussed in detail. Thus, our finding highlights that the multiresponsive nanocarriers are of great potential in the field of drug controlled release.
研究领域:
生物医学工程
·
纳米医学
·
药剂学
✓ 已验证
产品关联
DOI
高影响因子
DESALINATION
·
2020
·
IF 7.098
Fuqing Ma,Chaojie Cai,Xinzhen Zhao,Hilal Ahmad,Changkun Liu
A novel thin-film nanocomposite (TFN) forward osmosis (FO) membrane was fabricated by loading bovine serum albumin (BSA)/gold nanoparticles (GNPs) on the surface of a cockscomb-like nylon supporting membrane. The influence of the embedded BSA/GNPs on surface morphology , surface roughness , surface charge, separation, and FO performance of the TFN-FO membrane was investigated. The water flux of the BSA/GNPs-modified FO membrane could be increased to 55.2 ± 5.4 LMH, and the J s /J w value was substantially decreased to 0.034 g/L, indicating a high selectivity of the modified membrane. BSA/GNPs located between the top of the nylon supporting membrane and the bottom of the polyamide (PA) skin layer provided passage for water transport and increased the roughness of the PA layer, thus enhancing the effective area on which the osmotic pressure could act. In addition, BSA/GNPs located at the bottom surface of the nylon supporting membrane provided a nearly electroneutral surface in the solution and alleviated dilutive concentration polarization . In summary, choosing a nylon membrane with a special cockscomb-like surface structure as the supporting layer to load BSA/GNPs nanoparticles proved to be a creative and effective nano-modification method for fabricating high-performance TFN-FO membranes.
研究领域:
材料科学
·
膜技术
·
纳米技术
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2020
·Vol. 25
·期 20
·4789
·
IF 3.267
Xiang-rong Cheng,Wei Zhao,Wen-le Dong,Guo-wei Le
The edible and medicinal part ofInula nervosaWall. (Xiaoheiyao) is confined to its root without sufficient phytochemical and biological investigation. In this study, the secondary metabolites of root, stem, leaf, and flower ofI. nervosaWall. were visualized using Global Natural Products Social Molecular Networking (GNPS), MolNetEnhancer, XCMS(xcmsonline.scripps.edu) analysis, and `ili mapping based on high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) data to reveal their chemical differences. Among the 11 kinds of chemical repertoires annotated by MolNetEnhancer and 16 hits against the GNPS library, 10-isobutyryloxy-8,9-epoxythymol isobutyrate (1) was revealed as the most dominant and responsible marker between the roots and the other parts. Moreover, a battery of unique MS features as well as differential markers were discovered from different parts of the plant. The chemical differences contribute to the bioactivity differences, which presented in the 2,2-diphenyl-1-picryl-hydrazyl (DPPH)assay and H2O2-insulted HepG2 cells and were in significant correlations with the contents of1. real-time reverse transcription polymerase chain reaction (RT-PCR)results demonstrated thatI. nervosaWall. extracts upregulated the mRNA expression of nuclear factor E2-related factor 2(Nrf2), heme oxygenase 1(HO-1), NAD(P)H quinone dehydrogenase 1 (NQO1), manganese superoxide dismutase (MnSOD), and glutamate-cysteine ligase catalytic subunit (GCLC) actors involved in antioxidative response in H2O2-challenged HepG2 cells. These findings support the roots ofI. nervosaWall. as active parts ofXiaoheiyao, and also indicate the potential antioxidant activities of other parts.Keywords:Xiaoheiyao;GNPS molecular networking;MolNetEnhancer;XCMS online;Nrf2
研究领域:
植物化学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2024
·
IF 4
Junhui Du,Haibin Liu,Hongshuo Chen,Chuanjin Cui,Wensi Zhang,Xuechao Zhang,Zhang Bin
A competitive electrochemical aptamer biosensor for the selective detection of Pb 2+ was developed in this study. The PAMAM@Au hybrid materials and the bioprobe MB-GNPs-ssDNA were synthesized with chemical methods . Modified electrode with carboxylated graphene oxide was prepared via electrodeposition . PAMAM@Au was immobilized on the modified electrode using the EDC/NHS crosslinker, and aptamer (Apt) was bound to PAMAM@Au hybrid materials using the glutaraldehyde crosslinker. The assembly of MB-GNPs-ssDNA/Apt/PAMAM@Au/GO/SPCE biosensors was achieved through immobilizing bioprobe onto electrodes, based on the theory of aptamer-complementary chain reactions. The fabricated biosensor was characterized through electrochemical experiments, SEM, AFM , TEM, XPS and FTIR . The biosensor's performance was evaluated in a series of Pb 2+ aqueous solutions by differential pulse voltammetry (DPV), and the results demonstrated this biosensor had excellent repeatability, stability, and specificity. The detection range spanned from 0.5 pM/L to 500 nM/L, with a detection limit of 5 fM/L. Consequently, the proposed biosensor can serve as a reliable analytical tool for the sensitive detection of lead ions .
研究领域:
生物化学
·
分析化学
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2022
·Vol. 24
·期 46
·8060-8069
·
IF 3.756
Shu-Qin Qin,Wei Xu,Wen-Cai Ye,Ren-Wang Jiang
Guanidinium–naphthalenedisulfonic acid (GNPS) was used as a molecular catcher because (i) it contains a cavity and channel in the network; (ii) NH2+ can be used as a hydrogen bond donor, and SO3− can be used as a hydrogen bond acceptor; (iii) the co-planar naphthalene rings can form aromatic interactions with guest molecules. The liquid guests 1–8 [(−)-isopulegol (1), (−)-menthyl acetate (2), isoeugenol (3), 2,6-dimethylaniline (4), methyleugenol (5), 2,6-diisopropylaniline (6), methyl salicylate (7) and L(−)-carvone (8)] are successfully encapsulated in the cavity of GNPS and eight new crystals were obtained. Both aromatic and non-aromatic molecules form hydrogen bonds and C–H⋯π interactions with GNPS. Co-crystallization of 1–4 with GNPS led to stronger C–H⋯π interactions as compared to the previously reported GBPS. Furthermore, compounds 5–8 which were not co-crystallized with GBPS were found to be encapsulated in the cavity of GNPS. We found that the aromatic cavity of GNPS with hydrogen bonding and enhanced C–H⋯π interactions can be regarded as a useful tool for the structural determination of liquid molecules. Furthermore, the correct absolute configurations of 1, 2 and 8 can be assigned based on the small Flack parameters because of the presence of sulfur atoms in the host molecule GNPS.
研究领域:
化学晶体学
·
分子结构分析
·
材料科学
✓ 已验证
DOI
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2019
·Vol. 220
·期 9
·1800553
·
IF 2.622
Da Xu,Yanwei Gao,Yang Sun,Zhaoyang Wang,Zhenhua Jiang,Xiangyu Jiang,Haibo Zhang
Polyaryletherketones (PAEKs) with pendant pyrene groups are prepared and used to functionalize and disperse graphene nanoplates (GNPs). A variety of polymers with a range of pyrene contents are studied. A monomer with pyrene and two hydroxyl groups is designed and synthesized through the Suzuki reaction and used to prepare a series of pyrene-functioned PAEKs (Py-PAEKs) by copolymerization. Experiments demonstrate that Py-PAEKs have not only excellent solubility, but also excellent mechanical properties and outstanding heat resistance. In the same treatment condition, the concentration of GNPs that are modified by Py-PAEK with 40 molar percentage of pyrene (Py-40) increases 88 times of the concentration of pure GNPs in NMP. In addition, adding 0.5% GNPs, which is functionalized by Py-40 to PEEK resin, improves the flexural strength of polymer composite nearly 12% and while the tensile strength of these composites improves nearly 10% with a doubling of the strain at break.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
IET Nanodielectrics
·
2019
·Vol. 2
·期 3
·97-102
·
IF 0
Yi Chen,Zhen Kong,Wenqi Chen,Lv Xiao,Yong Yuan,Zhongquan Li,Qixin Zhuang
Graphite nanoparticles (GNPs) were introduced into poly(p-phenylene benzobisoxazole) (PBO) matrix to produce composites via in situ polymerisation. Films of various composites were fabricated through the solution casting method in methanesulfonic acid (MSA) with the help of two sand core plates. The interlayer spacing of GNPs increased slightly confirmed by XRD as a result of an expanding effect caused by continuously formed PBO chains between the graphene nanosheets of GNPs during polymerisation. Also, due to the uniform dispersion of GNPs into PBO matrix, composite films exhibited an improved tensile strength (258 MPa, 72% higher than that of pure PBO) with 5 wt% loading of GNPs fillers. The initial decomposition temperature of the composite is ∼630°C. Besides, benefitting from the interfacial polarisation in this conductive filler/polymer system, the dielectric constant of the composites with 10 wt% loading of GNPs reached 6.96, which were over two times higher than that of pristine PBO polymer (2.91).
研究领域:
材料科学
·
高分子科学
·
纳米技术
✓ 已验证
产品关联
DOI
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2026
·Vol. 46
·期 16
·118638
·
IF 6.3
Xueqi Gu,Xinyue Hu,Daheng Wu,Xian-Zong Wang,Jianxi Liu,Hong Yu,Cheng-Feng Du,Long Wang,Jun Yang
Yttria-stabilized zirconia (YSZ) is a promising candidate for abradable seal coatings (ASC) in aero-engines, yet its inherent high coefficient of friction (COF) limits further application. This study introduced dual solid lubricant phases consisting of graphene nanoplatelets (GNPs) and silica-coated hexagonal boron nitride (h-BN@SiO 2 ) with different mass fractions into YSZ, and their tribological performance was systematically evaluated from room temperature to 750 °C. The composite containing 15 wt% GNPs and 5 wt% h-BN@SiO 2 exhibited low and stable COF (below 0.3) and moderate wear rates. Notably, it achieved an ultra-low COF of 0.08 at 750 °C. This outstanding performance originates from the formation of a low-shear graphene/BN interlaced lamellar structure, while tribochemically formed silicate phases and molten boron oxide further enhance the overall tribological performance of the composite. This work proposes an effective design approach for the development of high-performance YSZ-based ASC materials across a broad temperature range.
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2019
·
IF 3.973
Feng Huo,Yuhang Liu,Yuran Tang,Yongqin Cao,Chao Tan,Feng Yang,Xiupei Yang
Au 11 (SG) 7 gold nanoparticles (GNPs) were synthesized from HAuCl 4 using thiol compounds containing an amino group to serve as both the reducing agent and the ligand. A three-dimensional network structure (…Au-SNH 2 →M n+ ⟵H 2 NS-Au…) was formed after the M n+ (Pb 2+ , Cd 2+ , Zn 2+ and Ag + ) coordinated the gold nanoparticles through the amino group in the thiol ligand, which promoted aurophilicity (…Au…Au…) and induced GNP aggregation and emission. The differences in coordination between the amino group and metal ions resulted in different emission wavelengths (Pb 2+ , Cd 2+ , Zn 2+ and Ag + : λ ex = 365 nm˜370 nm, λ em = 580, 645, 630 and 565 nm). Aggregation induced emission of amino thiol capped GNPs via coordination of Pb 2+ or Cd 2+ can be used as a fluorescent sensor of the both metal ions (λ ex = 365 nm, λ em = 580/645 nm) and were used for living bioimaging in vivo and in vitro.
研究领域:
纳米技术
·
材料科学
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2022
·Vol. 128
·期 9
·1-9
·
IF 2.983
Liu Fu,Wang Mingjie,Chen Yao,Gao Jianmin
When graphene is used to enhance reaction-bonded silicon carbide (RBSC), the problem of graphene being corroded by molten silicon should be considered. In this work, the polycarbosilane (PCS) was uniformly adhered to the surface of graphene nanoplatelets (GNPs) by the sol–gel method, and SiC barrier formed after pyrolysis. The structural evolution of GNPs in reaction sintering and the chemical structure of GNPs-PCS were investigated. The results showed that GNPs after siliconizing showed a porous structure, consisting of nanometer SiC particles on the surface. The ceramic yield and final pyrolysis temperature of PCS were reduced after mixing with GNPs and divinylbenzene (DVB). The SiC formed by the pyrolysis of PCS was uniformly distributed among GNPs. SiC whiskers (SiC w ) were observed in the sample of GNPs and GNPs-PCS after siliconizing. The difference and formation mechanism of SiC w in these two samples were discussed. After PCS modification and pyrolysis, GNPs survived in the loss on ignition experiment. The prepared composite powder further improved the toughness of GNPs/RBSC by 14.69%.
研究领域:
材料科学
·
陶瓷工程
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Jiayue Zhou,Dongmei Li,Tiantian Li,Ziwei Chen,Zhuxin Chang,Guanggui Yu,Ruicong Zhou,Linyuan Wang,Yinuo Chen,Jie Zhao,Huan Liu,Na Sai
A new biomimetic film was developed for the detection of 17β-estradiol (E2), drawing inspiration from the hydrophilic and hydrophobic (HI-HO) pattern of the beetle's back. The film had a non-densely packed face-centered cubic (FCC) structure of interwoven hydrophobic gold nanoparticles (GNPs) and hydrophilic poly ionic liquid methyl methacrylate (PILMMA) spheres. The film exhibited reflection (RE) and fluorescence (FL) emissions. The GNPs demonstrated a localized surface plasmon resonance effect (LSPR) and collaborated with PILMMA spheres to form a pronounced HI-HO pattern that promoted the concentration of target E2 molecules and increased sensitivity. After optimization, the film showed direct, ultrasensitive (as low as 1.5 nM), fast (11 min), and selective detection of E2 with a wide concentration range. During detection, RE and FL changes of the film were observed by the naked eye without any color display equipment. The recovery of E2 was between 87.0 % and 111.2 % in real samples.
研究领域:
分析化学
·
纳米技术
·
生物传感器
·
环境监测
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
METALS AND MATERIALS INTERNATIONAL
·
2020
·Vol. 27
·期 10
·4263-4270
·
IF 1.99
Chen Lili,Qi Yushi,Fei Yanhan,Du Zhiming
Abstract In order to significantly enhance the performance of graphene in metal matrix composites, in situ SiC nanorods were successfully fabricated to enhance graphene nanoplatelets (GNPs)-reinforced Al2024 composite, which was prepared by powder semi-solid processing and friction stir processing. The SiC–GNPs dispersed in the Al matrix uniformly, SiC nanorods were randomly grown on GNPs sheets in any direction, bridging GNPs as well as GNPs and the Al matrix. Meanwhile, the interfacial bonding was effective. The hybrid reinforcement of SiC and GNPs endowed composites with superior mechanical properties and thermal conductivity. The in situ SiC nanorods transfer phonons and reduce phonon scattering effect in the through-plane direction of GNPs, which conducive to heat transmission. The composite exhibits improved mechanical properties, maximum tensile strength and hardness of 589 MPa and 193 HV are obtained, with 1.0 wt% GNPs addition, respectively. The thermal conductivity of composite increases with the content of SiC–GNPs. When the content of SiC–GNPs reaches 1.5 wt%, the composite has significantly enhanced thermal conductivity (224 W m −1 K −1 ), which is 115% times higher than that of Al2024. Moreover, the effects of SiC–GNPs on the properties were discussed. Graphic Abstract
研究领域:
材料科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）