CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Fei Wang,Li Li,Chaohui Yang,Zhongxing Cai,Ziyi Guo,Siyu Hou,Xiaoya Xie,Yinghao Chen,Jing Huang,Long Zhang
A series of GdPO 4 :5%Eu 3+ micro/nanomaterials with different morphologies and crystal structures were successfully prepared by the one-step solvothermal method using only the gadolinium source, the phosphoric acid source and ethanol as solvents, without any surfactants or templates, without further calcination and by adjusting only the ratio of phosphoric acid and gadolinium sources. They all have good dispersion and homogeneity. The morphology of the products was mainly regulated by the ratio of H 3 PO 4 to Gd(NO 3 ) 3 · 6H 2 O, with ratios of 2:1, 8:1, 16:1, 24:1, 32:1, 40:1 and 48:1 mL/g resulting in the formation of square, pillow, star, carambola, hollow cylinder, drum and jujube shaped GdPO 4 :5%Eu 3+ micro/nanomaterials, respectively. Ratios of 2:1–24:1 and 32:1–48:1 allow for the direct solvothermal synthesis of monoclinic and hexagonal phase gadolinium phosphate, simultaneously. In addition to their crystal structure and morphology, chemical bonding, thermal stability and specific surface area, their luminescence properties and magnetic resonance imaging (MRI) tracing properties have also been studied in comparison. Interestingly, the GdPO 4 :5%Eu 3+ micro/nanoparticles in the carambola shape had a higher photoluminescence intensity and relaxation rate of 0.7709 mM −1 s −1 (r 1 ) among all the morphologies. The possible mechanisms by which various morphologies of GdPO 4 :5%Eu 3+ were prepared in different ratios were analyzed, and the reasons for their effects on the fluorescence and MRI tracer properties were further investigated. This study is of reference significance for the simple-regulated synthesis of rare earth inorganic gadolinium-containing micro/nanomaterials and provides a reliable guarantee for the expansion of their multifunctional applications in UV–Vis luminescence and MRI tracing for implants.
研究领域:
材料科学
·
医学影像学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Xinxin Wang,Zhihua Long,Wei Qian,Yunxia Ye,Fengze Dai,Yinqun Hua,Jie Cai
Tremendous efforts have been devoted to exploring alternative materials to 8 wt% yttria-stabilized zirconia used for thermal barrier coatings . In this work, novel composite ceramic GdPO 4 /GdTaO 4 was designed by introducing GdTaO 4 as second reinforcement phase into GdPO 4 matrix. Mechanical and thermophysical properties of resulting composites were studied as a function of doping concentration of GdTaO 4 . Results suggested GdPO 4 /GdTaO 4 composite ceramics consisting of GdPO 4 monazite and GdTaO 4 monoclinic phases, indicating GdPO 4 and GdTaO 4 with maintained excellent chemical compatibility at high temperatures. GdPO 4 /GdTaO 4 composite ceramics achieved superior hardness of 5.82 GPa, fracture toughness of 2.72 MPa m 1/2 , and thermal conductivity of 1.36 W•m −1 •k −1 at GT doping concentration of 50 wt% owing to grain refinement and scattering of phonons caused by the doped GdTaO 4 phase. In sum, excellent mechanical and thermophysical properties of GdPO 4 /GdTaO 4 composite ceramics look potential for thermal barrier coatings materials.
研究领域:
材料科学
·
陶瓷材料
✓ 已验证
产品关联
DOI
高影响因子
Royal Society Open Science
·
2020
·Vol. 7
·期 5
·
IF 2.646
He Bai,Yunjiang Yang,Jinrong Bao,Anping Wu,Yan Qiao,Xueyuan Guo,Mingyuan Wang,Wenxian Li,Ying Liu,Xiaowei Zhu
SiO2@GdPO4:Tb@SiO2 nanoparticles with core-shell-shell structure were successfully synthesized by a cheap silane coupling agent grafting method at room temperature. This method not only homogeneously coated rare-earth phosphate nanoparticles on the surface of silica spheres but also saved the use of rare-earth resources. The obtained nanoparticles consisted of SiO2 core with a diameter of approximately 210 nm, GdPO4:Tb intermediate shell with thickness of approximately 7 nm, and SiO2 outer shell with thickness of approximately 20 nm. This unique core-shell-shell structured nanoparticles exhibited strong luminescence properties compared with GdPO4:Tb nanoparticles. The core-shell-shell structured nanoparticles can effectively quench the intrinsic fluorescence of bovine serum albumin through a static quenching mode. The as-synthesized nanoparticles show great potential in biological cell imaging and cancer treatment.
研究领域:
材料科学
·
生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 28
·13632-13646
·
IF 4.682
Zhu Wenhao,Wu Zhenxu,Wang Peng,Liu Tianyi,Guo Min,Ji Jiansong,He Mingfeng,Wang Haifeng,Zhang Peibiao
Within brain tissue engineering, stem cell implantation assisted by biodegradable injectable scaffolds is a crucial method. However, implanted scaffolds, especially microcarriers, may translocate due to the fluidity of the materials. Therefore, the development of an MRI contrast enhancement microcarrier, which could noninvasively trace the location of the implant in vivo, is necessary to guide the evaluation of treatment prognosis. In this study, GdPO 4 ·H 2 O nanoparticles were utilized as the dispersed phase to endow PLGA microcarriers with T1-weighted MRI contrast ability. By adjusting the dispersed phase of Gd compound nanoparticle in PLGA Matrix, a cross-comparison experiment between MRI contrast enhancement imaging and biocompatibility was conducted, and 0.8% Gd was found to be the most suitable rate for preparing nano-composites. Moreover, 0.8% Gd/PLGA microcarriers were suspension-cultured with stem cells in vitro and implanted into traumatic brain injury rats in vivo. Excellent cytocompatibility and enhancement of the T1 phase of MRI were confirmed. This work created a T1-weighted MRI contrast-enhanced microcarrier, which provides a clinical noninvasive tracing cell scaffold for brain tissue engineering.
研究领域:
生物医学工程
·
干细胞研究
·
医学影像
·
神经科学
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale Advances
·
2022
·Vol. 4
·期 5
·1414-1421
·
IF 5.598
Hui Zhang,Jianping Zhang,Yi Chen,Tianze Wu,Mingzhu Lu,Zhenxia Chen,Yu Jia,Yongtai Yang,Yun Ling,Yaming Zhou
The size modulation of hollow carbon nanospheres (HCSs) has attracted great interest in the contexts of cellular uptake, drug delivery and bioimaging. In this study, a facile fabrication method was specifically used to minimize all influencing factors except for the particle size. A series of nanoparticles of hollow carbon nanospheres embedded with magnetic resonance imaging (MRI) nanoagent γ-Fe2O3 and GdPO4 nanoparticles (Fe–Gd/HCS), were successfully prepared and applied to in vitro/vivo evaluation with well-defined sizes of ∼100 nm (Fe–Gd/HCS-S), ∼200 nm (Fe–Gd/HCS-M), and ∼300 nm (Fe–Gd/HCS-L), respectively. Then the in vitro size effect of Fe–Gd/HCS was systematically investigated by bio-TEM, CLSM, CCK-8 assay, and flow cytometry revealing that Fe–Gd/HCS could be internalized and the cellular uptake amounts increase with the decrease of size. Furthermore, the in vivo size-effect behavior of Fe–Gd/HCS (∼100 nm, ∼200 nm, ∼300 nm) was tracked by MRI technique, demonstrating that all Fe–Gd/HCS can distinguish the liver, in which Fe–Gd/HCS with the smallest particle size exhibited the best performance among these nanoparticles. By leveraging on these features, Fe–Gd/HCS-S (∼100 nm) was further chosen as a theranostic agent, preliminarily presenting its capability for multi-modal imaging and therapy.
研究领域:
纳米医学
·
生物材料
·
医学影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2018
·Vol. 8
·期 39
·21857-21862
·
IF 2.936
Yu Gao,Yongkun Qiu,Xin Wang,Yanfeng Bi,Guiyan Zhao,Fu Ding,Yaguang Sun,Zhenhe Xu
GdPO4 hollow microspheres were synthesized by using a novel multi-step transformation synthetic route for the first time with polystyrene (PS) spheres as the template, followed by the combination of a facile homogeneous precipitation method, an ion-exchange process, and a calcination process. The XRD results indicated that the GdPO4 hollow microspheres have a pure hexagonal phase. The SEM and TEM images confirmed that the as-obtained GdPO4 hollow spheres have a uniform morphology with an average diameter of 2.7 μm and shell thickness of about 150 nm. The up-conversion luminescence properties as well as the emission mechanisms of the GdPO4:Yb3+, Ln3+ (Ln3+ = Tm3+, Er3+ and Ho3+) hollow microspheres were systematically investigated, which show blue (Tm3+, 1G4 → 3H6), green (Er3+, 4S3/2, 2H11/2 → 4I15/2), and red (Ho3+, 5F5 → 5I8) luminescence under 980 nm NIR excitation, providing potential applications in bioanalysis, optoelectronic and nanoscale devices, future color displays and light-emitting devices, and so on.
研究领域:
材料科学
·
纳米技术
·
发光材料
·
光电子学
·
无机化学
✓ 已验证
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2017
·Vol. 27
·期 11
·1605313
·
IF 12.124
Qianqian Zhang,Peiyuan Wang,Yun Ling,Xiaomin Li,Lixue Xia,Yongtai Yang,Xiaofeng Liu,Fan Zhang,Yaming Zhou
Developing a feasible way to prepare highly dispersed heterometallic nanoparticles incorporated in porous carbon composites is of significant importance for multifunctional materials. In this work, heterometallic γ-Fe 2 O 3 and GdPO 4 nanoparticles that are incorporated in ordered mesoporous carbon composites are facilely prepared by a one-pot in situ method using a Wells–Dawson-like cluster of [Fe 6 Gd 6 (μ 3 -O) 2 (CO 3 )(O 3 PPh) 6 (O 2 C t Bu) 18 ] ({Fe 6 Gd 6 P 6 } for short) as the precursor. It is verified that the γ-Fe 2 O 3 and GdPO 4 nanoparticles are highly dispersed and embedded into the carbon matrix with a particle size smaller than 5 nm, even when the carbon matrix is changed from 2D hexagonal P6mm to 3D body-centered cubic Im-3m symmetry. Additionally, a formation mechanism is proposed. Furthermore, dual-mode magnetic resonance (MR) imaging and drug carrier properties are evaluated by in vitro experiments, which show a satisfactory T 1 - and T 2 -weighted MR imaging effect with r 1 and r 2 relaxivity values of 2.7 and 183.7 mM −1 s −1 , respectively, and doxorubicin hydrochloride carrier amount of 102 mg g −1 , identifying a combined function for potential diagnostic and therapy.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
·
磁共振成像
·
药物递送系统
✓ 已验证
产品关联
DOI
高影响因子
PROGRESS IN NUCLEAR ENERGY
·
2016
·
IF 1.184
Cheng Meng,Xingeng Ding,Junchuan Zhao,Wenqi Li,Chunrong Ren,Hui Yang
Monazites are of considerable interest for immobilization of minor actinides . In this work, the Gd 1-x Ce x PO 4 (0 ≤ x ≤ 1) series is synthesized via conventional solid–state reaction using Ce as the surrogate for minor actinide americium (Am), with microstructure/phase structure characterized by XRD , HRTEM, μ-Raman, and SEM as well. The optimized temperature for preparation of monazite-type Gd 0.4 Ce 0.6 PO 4 solid solution is more than 1300 °C. At 1400 °C, the GdPO 4 ceramic is essentially monazite with little metastable xenotime phase. The metastable xenotime (GdPO 4 ) to monazite transformation occurs during the immobilizing phase of Ce element. The formation of monazite-type Gd 1-x Ce x PO 4 solid solutions in the range 0.1 ≤ x ≤ 1 is confirmed by the Rietveld refinement and Raman spectra . The change of Ce content has no significant influence on the morphology of the monazite-type Gd 1-x Ce x PO 4 compounds.
研究领域:
材料科学
·
核废料管理
·
陶瓷
·
固体化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）