ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 29
·期 17
·24589-24598
·
IF 4.223
Zhang Jun,Wan Yi-ping,Liu Ze-hua,Wang Hao,Dang Zhi,Liu Yu
It is important to keep natural estrogen conjugates (C-NEs) intact in aqueous environmental sample before sample preparation; otherwise, this may influence the accurate determination of NEs. Therefore, this work thoroughly investigated the stability of C-NEs in three different aqueous environmental samples under four different storage conditions, room temperature, low temperature of 4 °C, low pH of 3, and addition of HgCl 2 at 2 g/L. Results showed that C-NEs in aqueous sample were easily deconjugated under low temperature of 4 °C, which has been widely used in sample collection and storage. Both the low pH of 3 and addition of HgCl 2 at 2 g/L under room temperature could keep C-NEs intact in domestic wastewaters and river water within 36 h, but the latter could keep C-NEs stable longer. This work is the first to show that low pH of 3 alone could keep C-NEs intact, which suggested that the combined condition at low temperature of 4 °C that has been widely used could be omitted. Meanwhile, compared to pH adjustment, addition of 2 g/L HgCl 2 into aqueous sample is more convenient and practical for 24-h composite sampling, which may be widely applied.
研究领域:
环境科学
·
生物学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CATALYSIS
·
2023
·
IF 16.5
Xingzong Dong,Guangye Liu,Zhaoan Chen,Quan Zhang,Yunpeng Xu,Zhongmin Liu
Compared with the rapid deactivation of the Pd/AC catalyst, an eco-friendly Pd-[DBU][Cl]/AC ([DBU][Cl], 1,8-diazabicyclo[ 5.4.0 ]undec-7-ene hydrochloride) catalyst with enhanced stability was synthesized and applied in the hydrochlorination of acetylene. The Pd-20[DBU][Cl]/AC catalyst exhibits 96.7% acetylene conversion and 98.9% selectivity of vinyl chloride within the 24 h evaluation under the conditions of T = 180 °C, GHSV(C 2 H 2 ) = 360 h –1 and V (HCl)/ V (C 2 H 2 ) = 1.2. The enhanced stability of the Pd-[DBU][Cl]/AC catalyst is attributed to the prevention of the reduction of Pd(II) to Pd(0), the inhibition of the formation of coke deposition on the catalyst surface, and the reduction of the loss of Pd species during the reaction. TPD characterization and DFT theoretical simulations confirmed that the PdCl 2 -[DBU][Cl] complex has stronger adsorption of HCl and weaker adsorption of C 2 H 2 and C 2 H 3 Cl compared to PdCl 2 . Furthermore, the catalytic mechanism of acetylene hydrochlorination over the PdCl 2 and PdCl 2 -[DBU][Cl] site was put forward based on theoretical simulations. The good activity and stability of Pd-20[DBU][Cl]/AC in the 60 h lifetime test indicates that it is likely to be a promising alternative to HgCl 2 catalysts.
研究领域:
催化化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2022
·
IF 4.326
Songyuan Sun,Haomiao Xu,Yurui Fan,Zhisong Liu,Qinyuan Hong,Wenjun Huang,Zan Qu,Naiqiang Yan
The polyvinylchloride industry is an important mercury emission source derived from the decomposition of commercial activated carbon-supported mercuric chloride (HgCl2/AC, with 12–15 wt % HgCl2) in acetylene hydrochlorination. Our results indicated that the loss of mercury was ascribed to the Hg–Cl bond breaking from the HgCl2 molecule at elevated temperatures that resulted in slip Hg0 in the exhausted gas. Herein, we employed a novel strategy that uses chalcogen bonding (ChB, e.g., S-, Se-, and Te-) interactions to anchor HgCl2 molecules, to improve the thermal stability and catalytic performances. The mercury desorption temperature reached approximately 300 °C, which is much higher than the optimum hydrochlorination reaction temperature. Notably, low-mercury catalysts (5 wt % HgCl2) guaranteed high catalytic performances, and Se–HgCl2/AC exhibited 83% acetylene conversion efficiency and near-perfect 100% selectivity. Moreover, the online mercury monitoring results showed that Se–ChB significantly inhibited the escape of mercury during the reaction. Density functional theory results confirmed that the reaction followed an Eley–Rideal (E–R) mechanism, which showed that the strong adsorption of HCl endowed the catalyst with superior durability and facilitated the reaction by reducing the energy barrier from 0.94 to 0.54 eV. Thus, the new strategy for highly stable low-mercury catalyst preparation can solve the problem of mercury contamination and enhance the productivity of PVC production.
研究领域:
化学工程
·
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Mingguang Zhang,Jianping Yang,Lijian Leng,Hongxiao Zu,Wei Zheng,Jiefeng Chen,Hailin Zheng,Wenqi Qu,Zequn Yang,Hailong Li
Divalent mercury (Hg 2 + , mainly as HgCl 2 ) dominates the mercury species discharged from cement kiln flue gas , however, achieving effective control remains challenging. Herein, zinc sulfide (ZnS) was applied for HgCl 2 removal from cement kiln flue gas , showing superior adsorption performance among metal sulfides. ZnS achieved an unprecedented adsorption capacity of 426.1 mg ·g −1 at an optimal temperature of 160 °C, nearly 300 times higher than its Hg 0 adsorption capacity. The typical flue gas components (O 2 , H 2 O, NO and SO 2 ) displayed insignificant adverse effects on HgCl 2 adsorption. Such intriguing observation was ascribed to the inherent sulfur (S 2 2- and S 2- ) and newly-formed zinc chloride (ZnCl 2 ). The S 2 2- and S 2- sites facilitated the conversion of HgCl 2 into β-HgS and α-HgS, respectively. The HgCl 2 dissociation resulted in chlorination of ZnS to form ZnCl 2 which accelerated the initial HgCl 2 adsorption process . The moderate binding energy of HgCl 2 on the Zn sites of ZnCl 2 facilitated the migration of intermediate adsorption products to the S sites of ZnS to form HgS. This work not only provided a promising alternative to commercial activated carbons (ACs) for HgCl 2 removal from cement kiln flue gas, but also proposed new insights to guide the design of HgCl 2 adsorbents. Synopsis A high-efficient HgCl 2 removal strategy for cement kiln flue gas was developed, and the role of inherent sulfur and newly-formed ZnCl 2 in HgCl 2 adsorption over ZnS was proposed for the first time.
✓ 已验证
产品关联
DOI
高影响因子
TOXICOLOGY
·
2024
·
IF 4.8
Hong-Yu Fu,Yue Li,Han Cui,Jiu-Zhi Li,Wan-Xue Xu,Xi Wang,Rui-Feng Fan
Mercuric chloride (HgCl 2 ), a widespread environmental pollutant, induces ferroptosis in chicken embryonic kidney (CEK) cells. Whereas activating transcription factor 4 (ATF4), a critical mediator of oxidative homeostasis, plays a dual role in ferroptosis, but its precise mechanisms in HgCl 2 -induced ferroptosis remain elusive. This study aims to investigate the function and molecular mechanism of ATF4 in HgCl 2 -induced ferroptosis. Our results revealed that ATF4 was downregulated during HgCl 2 -induced ferroptosis in CEK cells. Surprisingly, HgCl 2 exposure has no significant impact on ATF4 mRNA level. Further investigation indicated that HgCl 2 enhanced the expression of the E3 ligase beta-transducin repeat-containing protein (β-TrCP) and increased ATF4 ubiquitination. Subsequent findings identified that miR-15b-5p as an upstream modulator of β-TrCP, with miR-15b-5p downregulation observed in HgCl 2 -exposed CEK cells. Importantly, miR-15b-5p mimics suppressed β-TrCP expression and reversed HgCl 2 -induced cellular ferroptosis. Mechanistically, HgCl 2 inhibited miR-15b-5p, and promoted β-TrCP-mediated ubiquitin degradation of ATF4, thereby inhibited the expression of antioxidant-related target genes and promoted ferroptosis. In conclusion, our study highlighted the crucial role of the miR-15b-5p/β-TrCP/ATF4 axis in HgCl 2 -induced nephrotoxicity, offering a new therapeutic target for understanding the mechanism of HgCl 2 nephrotoxicity.
研究领域:
毒理学
·
细胞生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
·
2017
·
IF 3.225
Cen Li,Wei Xu,Shengqi Chu,Zhiyuan Zheng,Yuancan Xiao,Linshuai Li,Hongtai Bi,Lixin Wei
Zuotai , a famous Tibetan medicinal mixture containing β-HgS, has been used to combine with herbal remedies for treating diseases for more than 1 300 years. The target organ for inorganic mercury toxicity is generally considered to be the kidney. Therefore, it is crucial to reveal the chemical speciation , spatial distribution and potential nephrotoxicity of mercury from Zuotai in kidney. To date, this remains poorly understood. We used X-ray absorption spectroscopy (XAS) and micro X-ray fluorescence (μ-XRF) imaging based on synchrotron radiation to study mercury chemical forms and mercury special distribution in kidney after mice were treated orally with Zuotai , β-HgS or HgCl 2 . Meanwhile, the histopathology of kidney was observed. Mice exposed with Zuotai showed kidney with significant proportion of mercury ions bound to sulfydryl biomolecules (e.g. Cys-S-Hg-S-Cys) plus some of unknown species, but without methylmercury cysteine, which is the same as β-HgS and HgCl 2 . The mercury is mainly deposited in renal cortex in mouse treated with Zuotai , β-HgS or HgCl 2 , but with a low level of mercury in medulla. The total mercury in kidney of mice treated with HgCl 2 was much higher than that of β-HgS, and the later was higher than that of Zuotai . And, HgCl 2 cause severe impairments in mouse kidney, but that was not observed in the Zuotai and β-HgS groups. Meanwhile, the bio-metals (Ca, Zn, Fe and Cu) micro-distributions in kidney were also revealed. These findings elucidated the chemical nature, spatial distribution and toxicity difference of mercury from Zuotai , β-HgS and HgCl 2 in mouse kidney, and provide new insights into the appropriate methods for biological monitoring.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）