Journal of Materials Chemistry C
·
2017
·Vol. 5
·期 15
·3757-3764
·
IF 5.256
Jiang-Shan Shen,Jia-Jia Wu,Xiang-Ying Sun,Zhen-Long Wu,Ping Gao,Bin Liu
We found that β-HgS nanocrystals could catalyze the reactions of oxidase substrates such as 3,3′,5,5′-tetramethylbenzidine (TMB) and O-phenylenediamine (OPD) to form coloured and fluorescent products, respectively, but α-HgS nanocrystals could not catalyze these reactions. Further investigation revealed that the predominantly exposed crystal planes may play an important role in determining the catalytic activity. On the basis of these findings, taken together with the reaction of forming a Schiff base between the –NH2 group of OPD and the –CHO group of formaldehyde, a novel, simple, and highly selective photoluminescence (PL) sensing platform for detecting formaldehyde could thereby be successfully developed.
研究领域:
纳米技术
·
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ANALYST
·
2011
·Vol. 136
·期 13
·2825-2830
·
IF 3.913
Fuqiang Zhang,Leyong Zeng,Cui Yang,Junwei Xin,Haiyan Wang,Aiguo Wu
A new approach for the detection of Hg2+ is reported based on color changes from which gold nanoparticles (Au NPs) are surrounded by a layer of HgS quantum dots to form in situ Au@HgS core–shell nanostructures. The surface plasmon resonance (SPR) absorption of the gold core was changed due to a shell layer of HgS formed on the surface of the Au NPs, which brings the colour change of the aqueous solution. Therefore, Hg2+ can be recognized by visualizing the colour change of the Au@HgS core–shell nanostructures, and can be detected quantitatively by measurement of the UV-vis spectra. Some effects on the detection of Hg2+ were investigated in detail. This method was used to detect Hg2+ with excellent selectivity and high sensitivity. In our method, the lowest detected concentrations for mercury ions were 5.0 × 10−6 M observed by the naked eye and 0.486 nM as measured by UV-vis spectra. At the range from 8.0 × 10−5 to 1.0 × 10−8 M of Hg2+, this method was shown to have a good linear relationship.
研究领域:
分析化学
·
纳米技术
✓ 已验证
DOI
高影响因子
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
·
2025
·
IF 3.3
Ziyan Han,Yuzhou Zhuo,Zhihui Dai,Xinhui Zhang,Bingqian Zhu,Yuyan Liu,Zhuoyu Chai,Jiayi Wu,Lijun Chen
Background Cinnabar is a mercury-containing mineral traditionally used in Chinese medicine and can induce kidney injury via mercury toxicity. Given that cinnabar contains elements such as selenium, it is reasonable to hypothesize that its multi-element composition may regulate nephrotoxicity through intermetallic interactions. To validate this hypothesis and clarify the distinct renal toxicity between cinnabar and single mercury compounds, we compared the nephrotoxic effects of cinnabar, Zhu-Sha-An-Shen-Wan (ZSASW), mercuric sulfide (HgS), and mercuric nitrate (Hg(NO₃)₂). By co-administration with sodium selenite (Na₂SeO₃), this study related to the nephrotoxicity of cinnabar was improved from the perspective of metal-element interactions, which provided a new perspective for the safety assessment of mercury-containing medicines. Methods Mice were gavaged with 0.5 % CMC-Na solution, cinnabar (50.0 and 200 mg/kg), HgS (50.0 mg/kg), Na 2 SeO 3 (1.00 mg/kg), cinnabar (50.0 mg/kg)+Na 2 SeO 3 (1.00 mg/kg), HgS (50.0 mg/kg)+Na 2 SeO 3 (1.00 mg/kg), ZSASW (600 mg/kg), ZSASW (600 mg/kg)+Na 2 SeO 3 (1.00 mg/kg) or Hg(NO 3 ) 2 (0.900 mg/kg in Hg 2+ ) daily for 30 days. Renal histopathology was assessed by H&E staining. Related protein expression was measured by Western blotting. Renal total Hg (THg) concentration in kidney was determined by cold vapor atomic fluorescence spectroscopy. Result Western blotting revealed significantly decreased OAT1 and GPX4 levels in all experimental groups compared to the Control group ( P < 0.05). NF-κB activation occurred in the Hg(NO₃)₂, Cinnabar-H, HgS, and HgS-Na₂SeO₃ groups. Hg(NO₃)₂ administration caused a significant decline in body weight growth rate ( P < 0.001), severe renal tubular degeneration with epithelial cell swelling, and the highest renal THg concentration (773.77 % exceeding the Control group). Na₂SeO₃ alone induced inflammatory infiltration and tubular epithelial degeneration. The Cinnabar-H and HgS groups exhibited distinct renal damage (localized tubular degeneration and vascular hyaline degeneration, respectively) with elevated renal THg concentration (330.74 % and 347.95 % exceeding the Control group). The Cinnabar-L, Cinnabar-Na₂SeO₃, ZSASW, and ZSASW-Na₂SeO₃ groups maintained normal histology despite increased renal mercury content (227.46 %, 40.57 %, 67.2 %, and 556.56 % exceeding the Control group). Co-administration of Na₂SeO₃ with HgS restored OAT1 and GPX4 expression ( P < 0.001), suppressed NF-κB activation, and minimally altered renal mercury accumulation (RSD=0.45 %). Na₂SeO₃ reduced mercury levels in the cinnabar-treated mice (57.07 % reduction) but increased accumulation in ZSASW-treated mice (292.65 % increase). Conclusion This study confirms that cinnabar and ZSASW exhibit lower toxicity than mercuric sulfide or mercuric nitrate. Multi-component synergistic or antagonistic effects need to be considered when studying the mechanism of action of cinnabar-related drugs.
研究领域:
毒理学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2021
·
IF 9.028
Yang Yang,Rui Huang,Wenqing Xu,Jixiang Zhang,Chaoqun Li,Jianfei Song,Tingyu Zhu
ZnS is a promising sorbent in recovering Hg0 from industrial flue gas due to its excellent Hg0 adsorption capacity. However, the internal structure–activity relationship still needs to be further clarified. In this work, ZnS sorbents with different structures were synthesized with the hydrothermal method by tuning the temperature. The samples had significant differences in the crystallinity, morphology, particle size, and sulfur (S) active sites. The results indicated that Hg0 removal performance was determined by the specific surface area and S active sites. ZnS synthesized at low temperatures (80-ZnS and 120-ZnS) had a larger surface area, while the S sites on the high-temperature-synthesized sample (160-ZnS) were more active for Hg0 adsorption. The 160-ZnS sample exhibited a much higher Hg0 adsorption amount per unit surface area. Further characterization revealed that S22– and Sx were the main active sites for Hg0 adsorption. Sx existed in the form of long-chain polysulfur (L-Sx) on 80-ZnS and 120-ZnS, while it exhibited in the form of short-chain polysulfur (S-Sx) on 160-ZnS. L-Sx had negligible adsorption ability, while S-Sx had a high affinity for Hg0. Hg0 can react with S22– and S-Sx, forming α-HgS and β-HgS, respectively. The new insight in this work can provide theoretical guidance for the design and structure optimization of ZnS, facilitating its practical industrial application.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Guopei Zhang,Cong Wang,Xiaoyang Zhang,Yong Dong,Zhaomin Li,Leteng Lin
Effective elemental mercury (Hg 0 ) removal from syngas is essential for industrial mercury control. This study synthesized LaMeO x /ZSM-5 (Me = Zn, Cu, and Fe) sorbents via the sol–gel method and evaluated their Hg⁰ removal performance for simulated syngas at 50–250 °C. The physico-chemical properties of samples were characterized by Brunauer-Emmett-Teller (BET), Scanning Electron Microscopy (SEM), X-ray diffraction (XRD), H 2 temperature-programmed reduction (H 2 -TPR) and X-ray photoelectron spectroscopy (XPS). La 2 CuO 4 /ZSM-5 demonstrated superior efficiency (≥95 %) at 50–200 °C under simulated syngas, attributed to its porous structure and abundant surface-active oxygen. H 2 S significantly enhanced Hg 0 removal by forming active sulfur species, while H 2 , CO, and H 2 O inhibited performance due to competition for active sites. The inhibitory effects were mitigated by adding 500 ppm H 2 S. XPS and TPD analyses revealed HgS (cinnabar) as the dominant mercury species, with Cu 2+ ions and active oxygen critical for Hg 0 capture. Stability tests confirmed excellent reusability, with over 88 % efficiency maintained after 10 adsorption-regeneration cycles. La 2 CuO 4 /ZSM-5 emerges as a promising sorbent for Hg 0 removal, offering high efficiency, stability, and resistance to syngas components, making it suitable for industrial applications.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2023
·
IF 11.4
Yuping Xiang,Yingying Guo,Guangliang Liu,Yanwei Liu,Maoyong Song,Jianbo Shi,Ligang Hu,Yongguang Yin,Yong Cai,Guibin Jiang
Mercury sulfide nanoparticles (HgSNPs), which occur widely in oxic and anoxic environments, can be microbially converted to highly toxic methylmercury or volatile elemental mercury, but it remains challenging to assess their bioavailability. In this study, an Escherichia coli-based whole-cell fluorescent biosensor was developed to explore the bioavailability and microbial activation process of HgSNPs. Results show that HgSNPs (3.17 ± 0.96 nm) trigger a sharp increase in fluorescence intensity of the biosensor, with signal responses almost equal to that of ionic Hg (Hg(II)) within 10 h, indicating high bioavailability of HgSNP. The intracellular total Hg (THg) of cells exposed to HgSNPs (200 μg L–1) was 3.52–8.59-folds higher than that of cells exposed to Hg(II) (200 μg L–1), suggesting that intracellular HgSNPs were only partially dissolved. Speciation analysis using size-exclusion chromatography (SEC)–inductively coupled plasma mass spectrometry (ICP-MS) revealed that the bacterial filtrate was not responsible for HgSNP dissolution, suggesting that HgSNPs entered cells in nanoparticle form. Combined with fluorescence intensity and intracellular THg analysis, the intracellular HgSNP dissolution ratio was estimated at 22–29%. Overall, our findings highlight the rapid internalization and high intracellular dissolution ratio of HgSNPs by E. coli, and intracellular THg combined with biosensors could provide innovative tools to explore the microbial uptake and dissolution of HgSNPs.
研究领域:
环境科学
·
微生物学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FUEL PROCESSING TECHNOLOGY
·
2019
·
IF 4.507
Shengji Wu,Pengjie Yan,Wangsheng Yu,Kai Cheng,Hui Wang,Wei Yang,Jie Zhou,Junhua Xi,Jieshan Qiu,Shouxin Zhu,Lei Che
Cerium-doped activated carbon with high dispersions of cerium and sulfur species was successfully synthesized by an in situ ion exchange method. A high space velocity was employed to differentiate the mercury removal performance of cerium-doped activated carbon with (Ce/AC) and without (Ce/C) activation in simulated flue gases , at 80 to 150 °C. The Ce/AC showed much higher mercury removal ability than those of Ce/C, commercial coconut AC and NH 4 Cl modified AC. The main mercury species formed over spent Ce/AC were HgO, HgS and HgSO 4 . The HgO was formed mainly through the oxidation of mercury by lattice oxygen, while the HgS was generated by the reaction between Ce 2 S 3 and mercury. The formation of HgSO 4 might be due to the reaction of mercury with SO 2 and/or Ce 2 S 3 with the aid of oxygen. The Ce/AC showed impressive regeneration and reuse ability, the mercury removal performance of which showed no obvious change even after 5 runs of regeneration. The mercury species formed over Ce/AC also had no obvious change after regeneration; however, the Ce 2 S 3 over Ce/AC was converted to CeO 2 after regeneration. With the above excellent properties, Ce/AC may prove to be an advantageous alternative to commercial AC for mercury removal in power plants.
研究领域:
环境科学
·
化学工程
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
·
2017
·
IF 3.225
Cen Li,Wei Xu,Shengqi Chu,Zhiyuan Zheng,Yuancan Xiao,Linshuai Li,Hongtai Bi,Lixin Wei
Zuotai , a famous Tibetan medicinal mixture containing β-HgS, has been used to combine with herbal remedies for treating diseases for more than 1 300 years. The target organ for inorganic mercury toxicity is generally considered to be the kidney. Therefore, it is crucial to reveal the chemical speciation , spatial distribution and potential nephrotoxicity of mercury from Zuotai in kidney. To date, this remains poorly understood. We used X-ray absorption spectroscopy (XAS) and micro X-ray fluorescence (μ-XRF) imaging based on synchrotron radiation to study mercury chemical forms and mercury special distribution in kidney after mice were treated orally with Zuotai , β-HgS or HgCl 2 . Meanwhile, the histopathology of kidney was observed. Mice exposed with Zuotai showed kidney with significant proportion of mercury ions bound to sulfydryl biomolecules (e.g. Cys-S-Hg-S-Cys) plus some of unknown species, but without methylmercury cysteine, which is the same as β-HgS and HgCl 2 . The mercury is mainly deposited in renal cortex in mouse treated with Zuotai , β-HgS or HgCl 2 , but with a low level of mercury in medulla. The total mercury in kidney of mice treated with HgCl 2 was much higher than that of β-HgS, and the later was higher than that of Zuotai . And, HgCl 2 cause severe impairments in mouse kidney, but that was not observed in the Zuotai and β-HgS groups. Meanwhile, the bio-metals (Ca, Zn, Fe and Cu) micro-distributions in kidney were also revealed. These findings elucidated the chemical nature, spatial distribution and toxicity difference of mercury from Zuotai , β-HgS and HgCl 2 in mouse kidney, and provide new insights into the appropriate methods for biological monitoring.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2022
·
IF 8.943
Peicheng Huang,Weichun Yang,Varney Edwin Johnson,Mengying Si,Feiping Zhao,Qi Liao,Changqing Su,Zhihui Yang
The contamination of soils by mercury (Hg) seriously threatens the local ecological environment and public health. S-functionalized amendments are common remediation technology , yet, Hg re-activation often occurs in the commonly used immobilization remediation by S-functionalized amendments, resulting in an unsatisfactory remediation effect. In this study, a novel FeS–Se functionalized biochar composite (FeS-Se-BC) amendment was prepared and applied for the efficient remediation of Hg-polluted soil. An immobilization efficiency of 99.62% and 99.22% for H 2 O-extractable Hg and TCLP solution-extractable Hg was achieved with the application of FeS-Se-BC (0.05) after 180 d. The analyses of XPS, Hg-TPD, SEM-EDS demonstrated that excellent remediation performance by FeS-Se-BC resulted from the synergistic effect of FeS and Se to form HgS and HgSe concurrently. In comparison to the treatments of biochar and FeS-functionalized biochar (FeS-BC), FeS-Se-BC promoted the transformation of exchangeable, carbonate-bound, and Fe–Mn oxides-bound Hg fractions into organic material-bound, and residual fractions, effectively reducing the risk of Hg-contaminated soil from a highly dangerous level to a low risk. Furthermore, the introduction of Se clearly inhibited the re-activation of Hg and reduced the release of Hg by 81.12% compared to FeS-BC when the ratio of S 2− to Hg was 5: 1 due to the formation of extremely stable HgSe. These results suggest that FeS-Se-BC has good potential for remediation of Hg-polluted soils which provides a new inhibitory idea for Hg re-activation after immobilization.
研究领域:
环境科学
·
土壤修复
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Wenxiao Tang,Beibei Chen,Man He,Gaofei Song,Yonghong Bi,Bin Hu
Understanding the interactions between mercury and microalgae, especially the interactions between inorganic mercury (IHg) and extracellular polymeric substances (EPS, a protective barrier between cells and their external environment), is essential for elucidating mercury’s toxicological mechanisms. Given the inherent cell heterogeneity, a novel analysis system of an online viscoelastic fluid focusing chip-time-resolved analysis inductively coupled plasma mass spectrometry has been developed to investigate the bioaccumulation of HgS nanoparticles and Hg2+ in single Microcystis aeruginosa (M. aeruginosa) cells, exploring the interaction mechanisms between HgS/Hg2+ accumulation in algal cells and EPS. The single-cell analysis results reveal minimal bioavailability of HgS within algal cells, with mercury’s toxicity to M. aeruginosa being species-dependent. Notably, algal cells exhibited more heterogeneity in HgS uptake than in Hg2+ uptake. Under Hg2+/HgS stress, M. aeruginosa cells with EPS removed (EPS-R algal cells) showed an increased level of bioaccumulation of mercury compared to those with EPS (EPS-C algal cells), highlighting the critical role of EPS in mercury bioaccumulation. Overall, the designed viscoelastic fluid microfluidic focusing chip integrates focusing and cleaning functions, featuring easy fabrication, simple operation, low sample loss, and relatively high throughput. Under the optimal conditions, the sample throughput is 1195 min–1 and the cell recovery is 90%. Besides, this research offers novel insights into the interaction mechanisms between Hg2+/HgS and EPS in microalgal cells and unveils the specific toxic effects of Hg2+/HgS on M. aeruginosa at the single-cell level, contributing to a deeper understanding of mercury’s ecological and toxicological impact in aquatic environments.
研究领域:
环境科学
·
毒理学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Environmental Science and Technology
·
2019
·Vol. 16
·期 12
·7705-7714
·
IF 2.031
Wu H.,Sun J.,Zhou C.,Yang H.
The introduction of additives into desulfurization slurry may inhibit the mercury re-emission from slurry and improve the stabilization of mercury in slurry. In this paper, the effect of common additives, such as sodium sulfide (Na 2 S), 2,4,6-trimercaptotriazine trisodium (TMT-18), sodium dithiocarbamate (DTCR-2) and Fenton reagent, on mercury distribution in gas–liquid–solid phase was investigated under typical operating conditions. Meanwhile, the effect of different additive dosages on the inhibition performance of mercury re-emission was studied. Furthermore, the inhibition mechanisms of different additives were also discussed. The experimental results showed that Na 2 S, TMT-18, DTCR-2 and Fenton reagent could inhibit the mercury re-emission from desulfurization slurry and some mercury that might reemit into the gas phase before would be restrained in the solid phase. For additives such as Na 2 S, TMT-18 and DTCR-2, with the increase in additive dosages, the inhibition performances of mercury re-emission were improved, but the enhancing effects tended to level off. More mercury could be restrained in the solid phase by forming HgS, Hg-TMT and Hg-DTCR. However, for additives such as Fenton reagent, the inhibition performance of mercury re-emission was first increased and then decreased with the proportion of Fe 2+ and H 2 O 2 in Fenton reagent increasing. There existed an optimal proportion. The oxygenated free radical generated by Fenton reagent with Fe 2+ as catalysis was the main reason for the inhibition of mercury re-emission, and more mercury would be oxidized and then restrained in solid phase due to the formation of HgSO 4 and Fe(OH) 3 .
研究领域:
环境工程
·
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）