MOLECULES
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2015
·Vol. 20
·期 4
·6601-6610
·
IF 2.416
Jie-Tao Pan,Bang-Wei Yu,Yong-Qin Yin,Jie-Hong Li,Li Wang,Li-Bing Guo,Zhi-Bin Shen
Six pentasaccharide resin glycosides fromIpomoea cairica, including four new acylated pentasaccharide resin glycosides, namely cairicoside I–IV (1–4) and the two known compounds cairicoside A (5) and cairicoside C (6), were isolated from the aerial parts ofIpomoea cairica. Their structures were established by a combination of spectroscopic, including two dimensional (2D) NMR and chemical methods. The core of the six compounds was simonic acid A, and they were esterfied the same sites, just differing in the substituent groups. The lactonization site of the aglycone was bonded to the second saccharide moiety at C-2 in1–4, and at C-3 in5–6. Compounds1and5,4and6were two pairs of isomers. The absolute configuration of the aglycone in1–6which was (11S)-hydroxyhexadecanoic acid (jalapinolic acid) was established by Mosher’s method. Compounds1–4have been evaluated for inhibitory activity against α-glucosidase, which all showed inhibitory activities.Keywords:Ipomoea cairica;resin glycoside;simonic acid A;α-glucosidase
研究领域:
植物化学
·
药理学
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DOI
PubMed
高影响因子
MARINE POLLUTION BULLETIN
·
2022
·
IF 7.001
Dayong Liang,Hua Xiang,Jianrong Xia
Ipomoea cairica (L.) Sweet is an invasive plant that cause serious invasion and damage in South China. Phaeocystis globosa is a common harmful algal bloom species on the southeast coast of China. Both species cause great environmental disturbances and serious economic damage to the localregion. This study explored the potential inhibitory effects of I. cairica leaf extracts on P. globosa . The results showed that solitary cells growth was inhibited at extract concentrations higher than 0.25 % (v/v). Although the colony diameter did not change, and the colony number increased rapidly in the first 36 h, we found that cells in the colonies had been damaged using scanning electron microscope and SYTOX-Green staining at 48 h. In addition, the rapid light-response curve of cells treated with extracts decreased, along with down-regulation of photosynthesis-related genes ( psbA, psbD, and rbcL ), suggesting damage to the photosynthetic system. Finally, the activities of antioxidant enzymes including superoxide dismutase, peroxidase, and catalase increased with increasing treatment time, indicating that cells activate antioxidant enzyme defense systems to alleviate the production of reactive oxygen species (ROS). Increased ROS levels disrupt cell membranes, alter cellular ultrastructures, and ultimately lead to cell death. This study not only achieved the reuse of invasive plant resources, but also demonstrated that I. cairica leaf extract has potential value as an algaecide.
研究领域:
环境科学
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海洋生物学
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植物学
·
生态毒理学
✓ 已验证
DOI
PubMed
高影响因子
Foods
·
2019
·Vol. 8
·期 6
·205
·
IF 3.011
Wei Zhang,Xianrui Liang
In this study, natural deep eutectic solvents (NADESs) were used as both the extraction and dilution matrix in static headspace gas chromatography-mass spectrometry (SHS-GC-MS) for the analysis of volatile components inIpomoea cairica(L).Sweet(ICS) leaves. Six NADESs were prepared and the NADESs composed of choline chloride and glucose with a 1:1 molar ratio containing 15% water were preferred due to the better peak responses. A total of 77 volatiles inICSleaves were detected and tentatively identified by mass spectral matching with the US National Institute of Standards and Technology (NIST, 2014) Mass Spectral Library and the retention index-assisted qualitative method. These 77 volatile components were mainly terpenoids, aromatics, and aliphatics. Among them, β-elemene, β-caryophyllene, α-humulene, and 2, 4-di-tert-butylphenol were found to be the main components. This investigation verified that the use of NADESs is an efficient green extraction and dilution matrix of the SHS-GC-MS method for direct volatile component analysis of plant materials without extra extraction work.Keywords:Ipomoea cairica(L.)Sweetleaves;natural deep eutectic solvents;static headspace gas chromatography-mass spectrometry;volatile components
研究领域:
分析化学
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植物科学
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植物化学
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产品关联
DOI
PubMed
高影响因子
Chinese Journal of Natural Medicines
·
2016
·Vol. 14
·期 3
·227-231
·
IF 1.382
Jie-Hong LI,Jie-Tao PAN,Yong-Qin YIN
In the present study, two new compounds from Ipomoea cairica were identified and demonstrated to have α-glucosidase inhibitory activity. They were isolated by column chromatography on silica gel and sephadex LH-20 and finally purified by prep-HPLC, with their structures being elucidated by spectroscopic methods, such as 1D- and 2D-NMR and HR-TOF-MS, and chemical methods. Compounds 1 and 2 , named cairicoside A and cairicoside B, were evaluated for α-glucosidase inhibitory activity by the MTT method, with the IC 50 values being 25.3 ± 1.6 and 28.5 ± 3.3 μmol·L −1 , respectively.
研究领域:
植物化学
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天然产物化学
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酶抑制
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药物发现
✓ 已验证
DOI
高影响因子
Scientific Reports
·
2020
·Vol. 10
·期 1
·1-10
·
IF 3.998
Ma Huiyan,Chen Yu,Chen Jinhui,Zhang Yunqiu,Zhang Tian,He He
Mikania micrantha and Ipomoea cairica are two invasive plants widely distribute and seriously damage in Hainan island. In this study, the leaves extracts of two weeds were collected and determined for their allelopathic potentials on Chrysanthemum coronarium . The phytotoxicity bioassay showed that when the extract concentration was 50 and 100 mg/ml, the inhibited effects of M. micrantha on growth of C. coronarium were greater than by I. cairica . However, when the extract concertation at 400 mg/ml, the opposite inhibited effects were observed. We speculated this phenomenon was caused by different allelopathic compounds. Therefore, using gas chromatography–mass spectrometry, 19 and 23 compounds were identified respectively, benzoic acid and cinnamic acid were the main components in the two leaves extracts, which were selected to carry out the further bioassays. Subsequent bioassay results showed the effects of two allelochemicals on morphological index and chlorophyll content and POD activity were all negative to C. coronarium , whereas the content of MDA and activity of SOD, CAT represented adverse changes. Moreover, the inhibitions by cinnamic acid were generally greater than those by benzoic acid. Thus, the phenolic acids played the most crucial roles in the allelopathic effccts of M. micrantha and I. cairica leaves extracts.
研究领域:
生态学
·
植物学
·
农学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）