NATURAL PRODUCT RESEARCH
·
2021
·
IF 2.862
Yi Lin,Jingjing Liang,Xiaogang Peng,Hanli Ruan
Three new phenolic compounds, 2,3,4-trihydroxy-1-(4′-hydroxybenzyl)benzoic acid (1), 2,3,4-trihydroxy-1-(4′-hydroxy-3′-methoxybenzyl)benzoic acid (2), and 2-(4′-hydroxy-3′-methoxybenzyl)-3,5-dimethoxy-1,4-benzoquinone (3), were isolated from the fresh pericarps of Juglans sigillata Dode. Their structures were elucidated by integrated spectroscopic techniques. Bioactivity screening results showed that compounds 1–3 exhibited moderate neuroprotective effects against H2O2-induced or CoCl2-induced cellular damage in human neuroblastoma SH-SY5Y cell line.
研究领域:
植物化学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
·
2018
·
IF 1.845
Binbin Shi,Wene Zhang,Xue Li,Xuejun Pan
The phenolics content and antioxidant activity of walnut (Juglans sigillata Dode) green husks were analysed during different stages of development. Contents of total phenolics and total flavonoids decreased from April 25th to June 7th, then increased during June and July, and decreased again at the beginning of August. Thirteen types of phenolic compounds were identified using HPLC of which juglone had the highest content. Because of seasonal variations, the trends of different phenolic compounds were different. Contents of both total phenolics and total flavonoids were strongly correlated with antioxidant activity; however, compared with totals, less significant correlations were observed between individual phenolic compounds and antioxidant activities.
研究领域:
植物科学
·
食品科学
·
植物化学
✓ 已验证
产品关联
DOI
高影响因子
NATURAL PRODUCT RESEARCH
·
2018
·
IF 1.928
Jingjing Liang,Xiaogang Peng,Jia Zhou,Ming Zhou,Hanli Ruan
One new diarylheptanoid (3S)-3′, 4″-epoxy-1-(4′-hydroxylphenyl)-7-(3″-hydroxylphenyl) heptane-3-hydroxy (1), together with eleven known ones (2–12), was isolated from the fresh pericarps of Juglans sigillata. Their structures were elucidated on the basis of extensive spectroscopic methods, including HR-ESI-MS, 1D and 2D-NMR. All isolates were evaluated for their cytotoxic activities in vitro against the growth of human cancer cells lines HT-29 and MCF-7 by MTT assay.
研究领域:
植物化学
·
药理学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMISTRY OF NATURAL COMPOUNDS
·
2019
·Vol. 55
·期 3
·435-439
·
IF 0.567
Liang Jing-Jing,Zhou Jia,Song Jian,Ruan Han-Li
Four new anthraquinones ( 1–4 ), along with four known ones ( 5–8 ) and five known naphthoquinones ( 9–13 ), were isolated from the green pericarps of Juglans sigillata. The structures of the new compounds were elucidated as 1,3-diethoxycarbonyl-8-hydroxy-9,10-anthraquinone ( 1 ), 1,3-diethoxycarbonyl-5-hydroxy-9,10-anthraquinone ( 2 ), 1-ethoxycarbonyl-8-hydroxy-9,10-anthraquinone ( 3 ), and 1-ethoxycarbonyl-5-hydroxy-9,10-anthraquinone ( 4 ), based on extensive spectroscopic methods including HR-ESI-MS and 1D and 2D NMR spectra. Compounds 1–12 were evaluated for their in vitro cytotoxicities against MCF-7 and HT-29 cancer cell lines by MTT assay. Compounds 3 and 7 showed weak cytotoxicities against HT-29 with IC 50 of 91.7 and 60.6 μM, respectively. Compounds 9–12 exhibited moderate cytotoxicities against MCF-7 and HT-29 with IC 50 ranging from 7.2 to 23.9 μM.
研究领域:
植物化学
·
药理学
·
肿瘤学
✓ 已验证
DOI
高影响因子
Foods
·
2024
·Vol. 13
·期 9
·1313
·
IF 4.7
Ping Li,Yujia Zhang,Changwei Cao,Yaxi Luo,Huan Kan,Yun Liu
Walnuts play a positive role in human health due to their large amounts of unsaturated fatty acids, whereas lipid oxidation can easily occur during storage. Herein, three natural antioxidants (epicatechin, sesamol, and myricetin) were added to the composite film cross-linked with chitosan and soy protein peptide, and the antioxidant film appropriate for the preservation of walnut kernels fromJuglans sigillatawas screened to improve the storage quality of walnuts. The results showed that three antioxidant films could all enhance the storage performance of walnut kernels, with sesamol being the best. The characterization of antioxidant film cross-linked with chitosan and soy protein peptide containing sesamol (C/S-ses film) revealed that the composite film improved the slow release and stability of sesamol; in addition, the presence of sesamol could effectively reduce the light transmittance and water vapor permeability of the composite film, together with significantly enhancing the antioxidant and antimicrobial activities, resulting in an effective prolongation of the storage period of walnut kernels. These findings indicated that C/S-ses possess excellent potential for retarding the oxidative rancidity of unsaturated fatty acids and will provide an effective strategy for the preservation of walnut kernels.
研究领域:
食品科学
·
材料科学
·
农业工程
✓ 已验证
DOI
PubMed
高影响因子
Food Chemistry-X
·
2025
·
IF 8.2
Wenyun Xiong,Lixin Ding,Wendie Cui,Lei Zhao,Shengbao Cai
This study aimed to investigate the effects of different lipid oxides on the physicochemical properties of proteins isolated from four walnut cultivars (YBWPI, NQWPI, XXWPI and STWPI). The main proteins in these WPIs are legume B-like and 11S globulin-like, and XXWPI contained the most unique proteins. In three simulation systems, YBWPI showed the greatest changes in carbonyl value, free sulfhydryl value and intrinsic fluorescence intensity. The secondary structure of STWPI changed obviously. NQWPI showed a unique subunit depolymerization, and its solubility and exogenous fluorescence intensity changed significantly, whereas emulsification and particle size of XXWPI changed the most. The 11S globulin-like and cupin type-1 domain-containing protein (A0A833YDI2) have stronger affinities with the key lipid oxides. The radius of gyration and total solvent accessible surface area values of the legumin B-like protein after oxidation reduced obviously. This study may help to better understand the interrelationship between lipid oxides and walnut protein properties.
研究领域:
食品科学
·
植物学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）