SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2013
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IF 1.977
Tianzhi Yu,Haifang Chai,Yuling Zhao,Chengcheng Zhang,Peng Liu,Duowang Fan
Two new mononuclear Cu(I) complexes based on 2-(2′-pyridyl)benzimidazolyl derivative ligand containing hole-transporting carbazole ( L ), [Cu(L)(DPEphos)](BF 4 ) and [Cu(L)(PPh 3 ) 2 ](BF 4 ), where L = (4-(9 H -carbazol-9-yl)phenyl)methyl-2-(2′-pyridyl)benzimidazole; DPEphos = bis[2-(diphenylphosphino)phenyl]ether and PPh 3 = triphenylphosphine, have been synthesized and characterized on the basis of elemental analysis, 1 H NMR and FT-IR spectra. The structures of the ligand L and the Cu(I) complexes were characterized by single crystal X-ray diffraction. The results reveal that in the Cu(I) complexes the central Cu(I) ions assume the irregular distorted tetrahedral geometry and are tetra-coordinated by the two nitrogen atoms from L ligand and two phosphorus atoms from ancillary ligands. The photophysical properties of the complexes were examined by using UV–vis, photoluminescence spectroscopic analysis. The complexes exhibit weak MLCT absorption bands ranging from 360 to 480 nm, and display strong orange phosphorescence in the solid states at room temperature, which is completely quenched in solutions.
研究领域:
化学
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材料科学
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DOI
PubMed
高影响因子
MOLECULES
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2023
·Vol. 28
·期 2
·722
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IF 4.6
Jinyuan Shi,Qianqian Wang,Chuang Li,Mengyu Yang,Muhammad Hussain,Junhui Zhang,Fengqin Feng,Hao Zhong
The roles of medium- and long-chain triacylglycerols (MLCT) on health benefits under high fat diet (HFD) conditions remain in dispute. This study was conducted to investigate the effects of novel LaPLa-rich MLCT on the glycolipid metabolism and gut microbiota in HFD-fed mice when pork fat is half replaced with MLCT and palm stearin (PS). The results showed that although MLCT could increase the body weight in the mouse model, it can improve the energy utilization, regulate the glucose and lipid metabolism, and inhibit the occurrence of inflammation. Furthermore, 16S rRNA gene sequencing of gut microbiota indicated that PS and MLCT affected the overall structure of the gut microbiota to a varying extent and specifically changed the abundance of some operational taxonomic units (OTUs). Moreover, several OTUs belonging to the generaDorea, Streptococcus, andg_Eryipelotrichaceaehad a high correlation with obesity and obesity-related metabolic disorders of the host. Therefore, it can be seen that this new MLCT has different properties and functions from the previous traditional MLCT, and it can better combine the advantages of MLCT, lauric acid, and sn-2 palmitate, as well as the advantages of health function and metabolism. In summary, this study explored the effects of LaPLa-enriched lipids on glycolipid metabolism in mice, providing theoretical support for future studies on the efficacy of different types of conjugated lipids, intending to apply them to industrial production and subsequent development of related products.Keywords:MLCT;lipid metabolism;glucose homeostasis;gut microbiota;inflammation
研究领域:
营养学
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代谢学
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微生物学
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动物科学
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DOI
PubMed
高影响因子
JOURNAL OF COORDINATION CHEMISTRY
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2018
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IF 1.703
Qian Li,Qiong Wei,Pei Xie,Li Liu,Xin-Xin Zhong,Fa-Bao Li,Nian-Yong Zhu,Wai-Yeung Wong,Wesley Ting-Kwok Chan,Hai-Mei Qin,Njud S. Alharbi
A series of three-coordinate dinuclear copper halide complexes containing acarbazolyl monodentate phosphine ligand, [CuX(dppc)]2 (dppc =3,6-di-tert-butyl-9-[2-(diphenylphosphino)phenyl]carbazole, X = I (1), Br (2), and Cl (3)), were synthesized, and their molecular structures and photophysical properties were investigated. The structural analysis reveals that two copper(I) centers are bridged by two halogen ligands to form a dinuclear structure with a four-membered Cu2X2 ring. Crystal structures of 1-3 contain 1-D supramolecular arrays constructed by intermolecular C–H···π interactions. These complexes exhibit blue to green emission in the solid state at room temperature and have peak emission wavelengths at 492–495 nm with microsecond lifetimes and low emission quantum yields (< 0.01%). The emission of 1-3 mainly originates from MLCT, XLCT, and IL (intraligand) transitions. The three complexes displayed good thermal stability.
研究领域:
无机化学
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材料科学
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光化学
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
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2016
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IF 4.712
Qiong Hu,Baojing Zhou,Pengyun Dang,Lianzhi Li,Jinming Kong,Xueji Zhang
We report a versatile approach for the colorimetric assay of alkaline phosphatase (ALP) activity based on the distinctive metal-to-ligand charge-transfer (MLCT) absorption properties of Fe(II)-phenanthroline reporter. In the presence of ALP, the applied substrate ascorbic acid 2-phosphate is enzymatically hydrolyzed to produce ascorbic acid, which then reduces Fe 3+ to Fe 2+ . The complexation of Fe 2+ with the bathophenanthroline disulfonate (BPS) ligand generates a blood-red Fe(BPS) 3 4− reporter, which is characterized by an intense MLCT absorption band at 535 nm in the visible range. Under optimal conditions, the spectral output exhibits a good quantitative relationship with ALP activity over the range of 0–220 mU mL −1 with a detection limit of 0.94 mU mL −1 . Moreover, the activity of ALP can also be conveniently judged through naked-eye observations. Results indicate that it is highly selective and can be applied to the screening of ALP inhibitors. In addition, it has been successfully employed to detect the endogenous ALP level of undiluted human serum samples, with a detection limit of 1.05 mU mL −1 being achieved. This approach avoids any elaborately designed substrates and holds considerable simplicity and flexibility for reporter design. This study broadens the horizon of the applications of phenanthroline-based transition metal complexes. Furthermore, an efficient and practical method like this has the potential to be widely used in clinical applications and in the point-of-care testing.
研究领域:
分析化学
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生物化学
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临床诊断
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DOI
PubMed
高影响因子
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