SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Huiping Zeng,Xiao Sun,Jie Zhang,Dong Li
The removal of dissolved organic matter from secondary effluent in sewage treatment is a significant challenge, necessitating the development of green and efficient composite magnetic materials for coagulation. In this study, activated carbon-modified magnetite nanoparticles (AC@MNPs) were synthesized via one-step activation pyrolysis using iron sludge as a precursor. The ballast coagulation process employed AC@MNPs as both magnetic species and adsorbent, with polymeric aluminum chloride (PACl) as a coagulant, for advanced treatment of secondary effluent. A response surface methodology identified optimal pyrolysis conditions: an activation ratio (KOH/ST) of 1.2, a pyrolysis time of 1 h, and a temperature of 640 °C. The influence of pyrolysis temperature (600 ∼ 700 °C) on the morphology and pore characteristics of AC@MNPs was investigated, highlighting its significance in coagulation performance. Characterization through XRD, VSM, and FTIR confirmed the favorable settling properties of the composite magnetic flocs and recyclability of AC@MNPs. Coagulation experiments revealed a synergistic effect of AC@MNPs and PACl, enhancing the removal of UV 254 and COD from 33.4 % and 36.2 % (with PACl alone) to 74.02 % and 76.53 %, respectively. The overall performance of the ballast coagulation process was evaluated, demonstrating effective removal of organics of various molecular weights. Finally, the coagulation mechanism was systematically discussed. Overall, this research offers insights into the application of magnetic coagulation technology for wastewater treatment advancements.
研究领域:
环境科学
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污水处理
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产品关联
DOI
高影响因子
Journal of Nano Research
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2017
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IF 0.511
Wan Xin Jia,Dong Tao Lu,Shao Min Shuang,Jun Yang,Chuan Dong
Magnetic chitosan nanoparticles (Fe3O4-CS MNPs) were synthesized by an improved one-pot hydrothermal method and applied for azo dye amido black 10B adsorption. The Fe3O4-CS MNPs were characterized by SEM, TEM, DLS, XRD, FTIR, TGA and VSM. The adsorptive behavior of amido black 10B on Fe3O4-CS MNPs was investigated using the UV-vis specteophotometric technique and the affecting parameters including solution pH, contact time, amido black 10B concentration and Fe3O4-CS MNPs amount were examined. The adsorption process followed the pseudo-second-order kinetic model. The adsorption equilibrium data fitted well with the Freundlich isotherm model with the saturated adsorption capacity of 124.8 mg/g at pH=2.0. The desorption experiment could be carried out using NaOH with the recovery of 91.78%. After five cycles, adsorption efficiency still reached 83.24%. The results showed that Fe3O4-CS MNPs possessed a simple synthesis route and excellent reusability, which have potential application in the adsorption of azo dye in environmental effluents.
研究领域:
材料科学
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环境科学
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化学工程
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2017
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IF 5.401
Yilin Wang,Pengjuan Ni,Shu Jiang,Wangdong Lu,Zhen Li,Hanmeng Liu,Jing Lin,Yujing Sun,Zhuang Li
In this paper, a novel, selective and eco-friendly biosensor has been fabricated and applied for sensitive detection of antibiotic oxytetracycline (OTC). This fluorescent biosensor was based on carbon quantum dots (CDs), H 2 O 2 and Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 MNPs). Herein, we firstly demonstrated that the fluorescence of CDs decreased apparently in the presence of OTC, H 2 O 2 and Fe 3 O 4 MNPs. The fluorescence quenching of CDs not only is caused by the hydroxyl radical produced from the Fenton reaction and complexation of Fe 3 O 4 MNPs with OTC, but also might be related to the inner filter effect (IFE) between CDs and OTC, which improved the selectivity and sensitivity of the fabricated biosensor. Under the optimal experiment conditions, the relative fluorescence intensity of the CDs decreased linearly with the increasing concentration of OTC from 25 nM to 1.75 μM. The detection limit of the fabricated biosensor on OTC was 9.5 nM at a signal-to-noise ratio of 3. Compared with other current protocols, the method described here displayed a few advantages including simplicity, low cost and rapid detection. The precision and reproducibility of the proposed sensor were also acceptable Significantly, the practicality of this sensitive sensor for OTC detection in drugs was further validated, revealing the advantages of high simplicity, sensitivity and selectivity. Hence, the developed biosensor might provide a useful and practical tool for OTC determination and related food safety analysis and clinical diagnosis.
研究领域:
分析化学
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环境科学
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食品安全
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生物技术
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DOI
高影响因子
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
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2024
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IF 2.7
Li-Hong Liu,Yu-Feng Liu,Hong-Bo Zhang,Xiao-Lei Liu,Han-Wen Zhang,Biao Huang,Fan Lin,Wei-Hua Li
PurposeDevelop an albumin nanoparticle-based nanoprobe for targeted glioblastoma (GBM) diagnosis and treatment, utilizing Angopep-2 for low-density lipoprotein receptor-related protein (LRP) targeting.MethodsCombined albumin-coated superparamagnetic iron oxide (SPIO), Carmustine (BCNU), and indocyanine green (ICG). Assessed morphology, size, Zeta potential, fluorescence, and drug encapsulation. Conducted in vitro fluorescence/MRI imaging and cell viability assays, and in vivo nanoprobe accumulation evaluation in brain tumors.ResultsANG-BSA/BCNU/ICG MNPs exhibited superior targeting and cytotoxicity against GBM cells in vitro. In vivo, enhanced brain tumor accumulation during imaging was observed.ConclusionThis targeted imaging and drug delivery system holds promise for efficient GBM therapy and intraoperative localization, addressing Blood-brain barrier (BBB) limitations with precise drug delivery and imaging capabilities.
研究领域:
纳米技术
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神经肿瘤学
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药物递送系统
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医学成像
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DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
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2015
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IF 5.636
Liping Dong,Shun Feng,Shanshan Li,Peipei Song,Jide Wang
In this work, a soft and nondestructive approach was developed to prepare concanavalin A-chelating magnetic nanoparticles (Con A-MNPs) for selective enrichment of glycoproteins. Ethylenediamine tetraacetic acid-modified-MNPs (EDTA-MNPs) were prepared by a one-pot chemical coprecipitation method first, and then, Cu(II) cations were used as bridge groups to immobilize Con A on EDTA-MNPs. The as-prepared absorbents with a mean diameter of 15 nm showed a strong magnetic response to an externally applied magnetic field. The results of thermogravimetric analysis showed the content of immobilized Con A was up to 28 wt %. For glycoprotein ovalbumin, the maximum capacity and equilibrium constant were 72.41 mg/g and 0.6035 L/mg, respectively. The as-prepared nanocomposites exhibited a remarkable selectivity for glycoproteins and can enrich glycoproteins specifically from a mixture of glycoprotein and nonglycoprotein even at a molar ratio of 1:600. It was also successfully applied for the enrichment of glycoproteins from real egg white samples. We expect that our finding will serve as a helpful template for others to design new adsorbents for enriching glycoproteins.
研究领域:
生物化学
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纳米技术
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蛋白质组学
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DOI
PubMed
高影响因子
RSC Advances
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2016
·Vol. 6
·期 72
·67875-67882
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IF 3.289
Weijun Fang,Chen Han,Huabing Zhang,Wenmei Wei,Rui Liu,Yuxian Shen
Pathogenic bacteria can lead to food poisoning and serious infectious diseases, and place a large burden on human health. A method for rapid capture and removal of the harmful bacteria from the contaminated source is essential and important. In this study, two types of amine group functionalized magnetic nanoparticles were successfully fabricated for effective capture of bacterial pathogens. These magnetic nanoparticles with a positive-charge surface strongly interacted with the negative-charge bacterial cell wall via electrostatic attractions to exhibit efficient adsorptive ability of a broad spectrum of bacterial pathogens. Owing to more cationic amine groups, the bacterial capture capacity of Fe3O4@sSiO2-PEI nanoparticles (PEI-MNPs) for E. coli BL21 was three times that of Fe3O4@sSiO2-NH2 nanoparticles (NH-MNPs), making them promising for practical applications. More importantly, the PEI-MNPs also showed excellent bacterial capture efficiency at a low concentration due to the multivalency effect that appeared in our system.
研究领域:
生物医学工程
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微生物学
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
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2020
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IF 4.3
Kelin Shen,Yi Cui,Dongao Zhang,Meiying Liu,Hongye Huang,Xuefeng Sha,Fengjie Deng,Naigen Zhou,Xiaoyong Zhang,Yen Wei
In this work, we reported the preparation of MoS 2 -based Fe 3 O 4 magnetic composites (MoS 2 -Fe 3 O 4 MNPs) through the biomimetic strategy, which relied on the self-polymerization of dopamine under alkaline aqueous solution. The utilization of MoS 2 -Fe 3 O 4 MNPs as catalysts for Fenton reaction to degrade organic dyes was also examined in details. A number of experimental parameters, including concentrations of H 2 O 2 , dosages of MoS 2 -Fe 3 O 4 MNPs and pH values on the degradation efficiencies were evaluated. The mechanism for catalytic degradation of methylene blue through Fenton reaction was illustrated by electron spin resonance (ESR) measurement and results indicated that the generation of ·OH and ·O 2 − is the major reason for the degradation reaction. The results from recycle experiments suggest that catalysts possess good reusability. We demonstrated that Fe 3 O 4 MNPs would be well dispersed on the surface of MoS 2 sheets relied on the linkage by polydopamine (PDA), which prevented the aggregation of Fe 3 O 4 MNPs and thus maintained high efficiency. Furthermore, we proved that the catalysts could also have high removal efficiency under low catalyst dosage and H 2 O 2 concentration. In conclusion, we believed the MoS 2 -Fe 3 O 4 MNPs could be successfully fabricated via the biomimetic strategy and should be promising candidates for environmental treatment. The biomimetic method should be also expanded for fabrication of other functional composites owing to the universal adhesion of PDA.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2023
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IF 9.5
Wenxuan Zhao,Biao Zhao,Zhengchen Wu,Ke Pei,Yuetong Qian,Kaicheng Luo,Chunyang Xu,Min Liu,Min Wang,Jincang Zhang,Renchao Che
Intrinsically conductive polymers have attracted much attention in the electromagnetic interference (EMI) shielding field because of their high conductivity and favorable flexibility. Delocalized π-electrons migrating along the conjugated long-chain structures can form a current. Based on this special conductive mechanism, the doping process significantly influences the conductivity and EMI shielding efficiency (SE). However, it is challenging to investigate the influence of the doping process on EMI shielding performance, which would enable the optimization of dopant selection. In this study, dopant engineering was explored for controllable conductivity, EMI SE, and mechanical properties. Polypyrrole (PPy) doped with various dopants serves as a conductive coating owing to its adjustable conductivity and abundant functional groups. Elastic thermoplastic polyurethane was chosen as the porous framework because of its high tensile strength, and magnetic nanoparticles supplied the magnetic loss in the 3D network. Eventually, the composite film showed the best properties when PPy was doped with sodium p-toluenesulfonate. The film exhibited an average SE of 26.3 dB in the X band and a specific SE of 1563.17 dB cm2 g–1 with a thickness of merely 0.2 mm. This film withstood a tensile stress of 16.0 MPa, while the breaking elongation ratio reached 538.0%. After 10,000 cyclic bending, 92.3% of the EMI shielding property was retained. In summary, this study highlights the most suitable dopant for EMI shielding applications and provides a prospective alternative for advanced, flexible, and smart devices.
研究领域:
材料科学
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电子工程
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产品关联
DOI
PubMed
高影响因子
Chemosensors
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2023
·Vol. 11
·期 2
·73
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IF 4.2
Ying Song,Kunyue Xiao,Qiang Chen,Xiaodong Zhang,Zhi Yu,Wenwen Chen,Xiubing Zhang,De Zhang,Dejiang Ni,Pei Liang
The detection of bifenthrin is closely related to the adsorption of SERS substrates. In this study, superparamagnetic Fe3O4@Au MNPs coated with GO were used to detect the adsorption and enrichment of bifenthrin molecules with benzene rings. Firstly, the thermal solvent method synthesized Fe3O4magnetic nanoparticles (MNPs) with a particle size of ~250 nm. Next, polyethylene imide (PEI) was used as an intermediate layer to modify the surface of Fe3O4to form a positively charged ultra-thin polymer middle layer. Next, the gold shell was developed by adsorption of ~20 nm AuNPs, without affecting the magnetic properties. Then, the additional amount of colloidal gold and GO on SERS performance was systematically studied. Using crystal violet (CV) as the probe, we investigated the SERS performance of composite nanomaterials. The lowest detected concentration reached 10−8mol/L, confirming that the composite functional material had good SERS activity and magnetic properties. Finally, the substrate was used to detect bifenthrin in an acetone solution, and the lowest detection concentration was 10−8mol/L. These results showed that the prepared GO/Fe3O4@Au MNPs were efficient SERS substrates that could detect bifenthrin pesticide residue with high sensitivity.
研究领域:
材料科学
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环境科学
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分析化学
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产品关联
DOI
高影响因子
ACS Applied Bio Materials
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2020
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IF 0
Weijun Fang,Wenjuan Zhu,Hu Chen,Hanyuan Zhang,Shi Hong,Wenmei Wei,Tingting Zhao
Developing of multifunctional nanoplateforms for simultaneous accurate cancer detection and target therapy is essential in cancer treatment. Herein, we present a facile synthesis of DOX/MNPs-FA nanocomposites for high-performance MRI and tumor-targeted drug delivery. In such core–shell structured DOX/MNPs-FA nanocomposite, the high magnetism of iron oxide core can be tuned and achieved by controlling the Zn2+ dopant amount, making them suitable as excellent contrasts in T2-weighted MR imaging. The outer porous silica shell with large pores about 5.4 nm in diameter possesses high surface area and pore volume. Anticancer drug (DOX molecules) can be stored in the large pore channels and is triggered to be released under acidic condition (pH 4–6). Importantly, the presence of folic acid on the surface of DOX/MNPs-FA allows the targeted delivery of the DOX to tumor cells, and therefore improves tumor chemotherapy efficiency. Our in vitro studies also demonstrated that DOX/MNPs-FA could be efficiently internalized into HeLa cells via the folate receptor-mediated endocytosis, and generate a greater cytotoxicity toward cancer cells compared to free DOX and DOX/MNPs. Therefore, these DOX/MNPs-FA multifunctional nanocomposites have great potential applications for simultaneous tumor diagnosis and targeted chemotherapy.
研究领域:
生物医学工程
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癌症治疗
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材料科学
✓ 已验证
产品关联
DOI
PubMed
BIOCHEMICAL ENGINEERING JOURNAL
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2021
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IF 3.978
Jie Li,Yuxiang Yang,Zhiyong Han,Min Zhao,Hongming Yuan,Chaoying Ni
Entrapment of enzyme in a cage structure of alginate/silica composite gel can maintain the chemical or configurational structures unchanged in the enzyme, providing a promising means of enzyme immobilization. The alginate/silica composite gel can also provide more adsorption sites for the substrate, which is biocompatible and will carry out degradation and adsorption of pollutants within a cage-like structure reactor simultaneously. In this study, we used a magnetic host-guest cage structured MNPs@ALG@SiO 2 composite with a specific enzyme embedded as its guest in the host matrix, to enhance its performance. Additionally, its swelling, leakage rate and immobilization conditions were optimized. The magnetic nanoparticles (MNPs) were used to compensate for the ease of collapse of the internal structure of alginic acid, while SiO 2 was used to enhance the swelling resistance of the carrier and prevent the degradation of polysaccharides in the natural environment, thereby maintaining the enzyme biological activity and immobilization rate. Finally, the effects on the degradation of tetrachloroguaiacol (TeCG) by the immobilized enzyme embedded in the MNPs@ALG@SiO 2 composite were investigated. When the concentration of ALG was 2% and the TEOS concentration was 40 %, the immobilized MNPs@ALG@SiO 2 was found to perform the best. The optimum conditions of immobilizing laccase are pH = 5, enzyme concentration 0.4 g/L, adsorption time 12 h and temperature 20 ℃. The degradation conditions of TeCG are pH = 6, degradation temperature 40 ℃, degradation time 10 h and the degradation products of TeCG were acetic acid and ethanol according to GC–MS.
研究领域:
环境科学
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生物技术
✓ 已验证
DOI
高影响因子
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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2021
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IF 3.935
Tianfeng Wan,Wenqing Li,Zilin Chen
A novel magnetic solid-phase extraction (MSPE) method based on metal organic framework-801 (MOF-801) modified magnetic nanoparticles (noted as PEI-MNPs@MOF-801) was successfully prepared for the extraction of preterm labor treatment drugs (including indometacin, acemetacin and sulindac) from human plasma sample. MOF-801, a new kind of porous coordination polymer composed of Zr 4+ and fumaric acid, was modified on the surface of synthesized polyethyleneimine magnetic nanoparticles (PEI-MNPs) through amidation reaction. The obtained PEI-MNPs@MOF-801 was characterized with Fourier-transformed infrared spectroscopy, X-ray photoelectron spectroscopy, X-ray diffraction and transmission electron microscopy. A MSPE-HPLC-UV method was developed by coupling PEI-MNPs@MOF-801 with HPLC system. Several parameters that affect the extraction efficiency including acetonitrile content, NaCl content, extraction time and sample volume were investigated. Under optimum conditions, the proposed MSPE-HPLC-UV method showed high extraction efficiency (enrichment factors between 96–118), good linearity with R ≥ 0.9987, excellent reproducibility (RSD ≤ 4.30 %) and low limits of detection in the range of 0.03−0.05 ng/mL. This method was also successfully applied to the extraction of indometacin, acemetacin and sulindac in human plasma samples and good recoveries were obtained.
研究领域:
分析化学
·
药学
✓ 已验证
DOI
PubMed
高影响因子
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