INORGANIC CHEMISTRY COMMUNICATIONS
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2024
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IF 4.4
Bingzhen Ma,Wangye Hu,Yue Zhou,Yangyang Li,Yuhui Zhang,Meiqi Zhou
MOF@COF hybrid materials not only have high stability and adjustable function, but also have the characteristics of MOFs and COFs materials, which make them have important application value in the field of adsorption. This article employs 1,3,5-benzene tricarbonyl chloride and p -Phenylenediamine as covalent organic framework monomers. Through the in-situ growth of covalent organic frameworks (COF) on the surface of NH 2 -MIL-88(Fe) material, a novel, stable, and porous COF-on-MOF hybrid material (NH 2 -MIL-88(Fe)/COF) was synthesized. The structure, morphology, and performance of the hybrid material were thoroughly examined using characterization techniques, including Fourier-transform infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), and thermal gravimetric analysis (TGA). Subsequently, We explored the MOF@COF hybrid material as an effective adsorbent for removing organic dyes, namely methylene blue (MB), methyl orange (MO), and crystal violet (CV). The influence of various adsorption parameters, such as adsorption time, initial dye concentration, and different pH values, on dye adsorption performance was systematically investigated. Experimental results revealed that at pH = 7, NH 2 -MIL-88(Fe)/COF demonstrates maximum adsorption capacities of 114 mg·g −1 , 106 mg·g −1 , and 102 mg·g −1 for methylene blue, methyl orange, and crystal violet, respectively. The adsorption process follows pseudo-second-order kinetics and Langmuir isotherm models. Lastly, NH 2 -MIL-88(Fe)/COF maintains high removal efficiency for the three dyes even after five repeated uses, establishing it as a stable and efficient adsorbent. The research findings suggest that MOF@COF hybrid materials hold promising applications in the treatment of dye-containing wastewater.
研究领域:
材料科学
·
环境科学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Ping Xue,Xin Pan,Jiming Huang,Yijun Gao,Wei Guo,Junsheng Li,Mi Tang,Zhengbang Wang
Construction of porous metal–organic framework (MOF)/covalent organic framework (COF) hybrid photocatalysts for enriched structures and unprecedented properties is still a great challenge but highly desirable. Herein, a new series of Cu3(HHTP)2-MOF/Tp-Pa-1-COF hybrids with different MOF content are successfully fabricated. The as-prepared MOF/COF hybrids exhibit intimate interaction based on the coordination of Cu ions with the carbonyl oxygen and enamine nitrogen groups in Tp-Pa-1. The integrated conductive Cu3(HHTP)2 is able to act as an excellent electron extractor instead of noble metal cocatalysts to significantly promote the charge transfer and inhibit the recombination of photogenerated electron–hole pairs. As a results, the optimized photocatalyst with Cu3(HHTP)2:Tp-Pa-1 ratio of 1:15 achieves the highest hydrogen evolution rate of 1.76 mmol·h–1·g–1 under visible-light irradiation, which is about 93 times higher than that of the pure Tp-Pa-1 and even slightly higher than that of the Tp-Pa-1 with Pt (3 wt %) as a cocatalyst.
研究领域:
材料科学
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能源化学
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DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2023
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IF 4.5
Xiaoxian Hu,Jing Qian,Juan Yang,Xiaomin Hu,Yanjiao Zou,Nianjun Yang
Covalent organic frameworks (COFs), a newly emerging kind of porous material, have gained extensive attention due to their fascinating structural features. However, the superiority of COFs as electrochemical sensing materials has not yet been adequately explored. Herein, a new type of core–shell metal–organic framework (MOF)@COF composites are synthesized through in situ growth of TAPB-DMTP-COF on the pre-synthesized Ce-BDC core. The thickness of the COF shell can be controlled to 20–50 nm by adjusting the Ce-MOF mass. It is found that the obtained MOF@COF composite possesses a larger electrochemical active area and faster electron transfer kinetic than its single component. As a case application of this composite, it has been employed as a sensing material for voltammetric detection of metol, where a linear range from 0.1 − 200 μM and a detection limit of 30 nM have been obtained. This study provides a new strategy to synthesize COF-based electrode materials as well as to explore their electrochemical properties and applications.
研究领域:
材料科学
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电化学
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纳米技术
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产品关联
DOI
高影响因子
CRYSTENGCOMM
·
2025
·
IF 2.6
Ming-Li Ma,Le-Chen Zheng,Rui Li,Yabo Xie
MOF@COF heterostructures featuring abundant porosity, designable structures and efficient separation of photogenerated charge carriers are enthusiastically embraced as promising candidates for the capture and conversion of CO2. Nonetheless, the laborious synthesis procedures involving energy-consuming protection and degassing steps severely impede their widespread application. In this study, a concentration-acid co-regulation strategy was developed to synthesize highly efficient MOF@COF composites in atmospheric air, obviating the need for vacuum, inert gases, and/or repeated freezing. With reduced supersaturation of the synthesis mixtures and intensified competitive coordination from acid modulators, the crystallization of COFs was strategically confined to the exterior surfaces of MOFs, fostering intimate contact to facilitate the interphase electron transfer. The synthesized MOF@COF heterostructures thereby exhibited radically enhanced CO2RR performances, yielding ca. 2.5 times more CO than the original deficiently-contacted composite. Moreover, the versatility of the synthesis strategy was validated using altered MOF and COF structures, shedding light on the significance of crystallization regulation in fabricating advantageous heterostructures. These findings are poised to effectively propel the development and practical implementation of MOF@COF composites.
研究领域:
材料科学
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环境科学
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化学工程
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产品关联
DOI
高影响因子
TALANTA
·
2025
·
IF 6.1
Yingfei Hui,Hao Guo,Mingyue Wang,Liping Peng,Borong Ren,Yanyan Ma,Wu Yang
Glutathione (GSH) levels have been linked to aging and the pathogenesis of various diseases, highlighting the necessity for the development of sensitive analytical methods for GSH to facilitate disease diagnosis and treatment. In this study, we synthesized a novel core-shell material, UiO@TBTA, by in-situ growing TFPB-TAPA COF on UiO-66-NH 2 through a Schiff base reaction. The resulting composite capitalize on the advantages of both materials, demonstrating excellent stability, large specific surface area, and abundant active functional groups while preserving superior crystallinity. Notably, this strategy effectively reduces the occurrence of aggregation-caused quenching (ACQ) in COFs. Due to the inner filter effect and hydrogen bonding interactions between UiO@TBTA and GSH, a specific ratiometric fluorescence detection of GSH was achieved in the range of 0.1–7 μM, with a limit of detection (LOD) of 0.0685 μM. In addition, due to the sensitive color change of the sensing material from orange to black caused by GSH, a proportional colorimetric sensing strategy has also been proposed, enabling the detection of GSH within the range of 1–200 μM. What's more, two intelligent artificial neural networks models were constructed with the help of machine learning that can quickly, accurately, and sensitively determine the concentration of GSH based on fluorescence images and color photographs respectively. Our work represents the first study utilizing MOF@COF composite for the multimodal detection of GSH, thus providing a novel strategy for the multimodal detection of the target analyte. Prospectively, the construction of the fluorescence/colorimetric dual-mode intelligent ratiometric sensing platform using deep machine learning holds great promise for real-time monitoring.
研究领域:
分析化学
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生物医学
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材料科学
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产品关联
DOI
PubMed
高影响因子
POLYMER
·
2025
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IF 4.5
Ren Li,Yueyuan Zhu,Xiuwen Zhang,Shuangying Li,Dong Wang,Zhaopeng Liu,Xinyao Wang,Yushun Hou,Shaoxiang Li
This article presents the synthesis of a porous hybrid material, comprising a melamine-terephthaldehyde-based two-dimensional π-conjugated covalent organic framework (COF) grown on a zinc-based metal-organic framework-5 (MOF-5). This hybrid material serves as a drug-loading platform for delivering penicillin G sodium salt. The material leverages the unique interactions between its benzene ring structure and β-lactam drugs, such as penicillin G sodium salt, as well as π-π stacking interactions, cations, and aromatic systems for drug adsorption. The pH responsiveness of the release phase is attributed to the attack of hydrogen ions on these interactions within the corrosion inhibition system. SEM, infrared spectrometry, and X-ray diffraction results confirm the successful synthesis of MOF@COFs. Drug adsorption experiments indicate that the material's maximum loading capacity reaches 51.23 % ± 0.57. Release experiments at different pH levels reveal that MOF@COFs exhibit pH responsiveness, achieving an optimal release rate and duration at pH 5.0, with a release time of approximately 12 h. Bacterial and biological toxicity tests confirm the material's expected antibacterial efficacy and safety for practical applications.
研究领域:
材料科学
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药物化学
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纳米技术
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药物递送系统
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生物无机化学
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产品关联
DOI
高影响因子
CHEMOSPHERE
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2023
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IF 8.8
Lijie Liu,Bing Zhao,Dedong Wu,Xiangxue Wang,Wen Yao,Zixuan Ma,Hairui Hou,Shujun Yu
Both environment and human beings were menaced by the widespread application of radioactive uranium, high-performance and effective elimination of uranium from wastewater is of important meaning for development of environmental sustainability in the future. In this study, the water-stable MOF material and the highly crystalline COF were compounded by a mild hydrothermal strategy, which achieved efficient removal of U(VI) through the synergistic effect. The composites showed the characteristics of both COFs and MOFs, which will possess higher stability, larger surface area and faster adsorption efficiency that cannot be carried out by a single component. Batch experiments and characterizations (SEM, TEM, XRD, FT-IR, BET, XPS, etc.) indicated that UiO-66-NH 2 @LZU1 had more stable and multi-layer pore structure and rich active functional groups. The Langmuir model and the pseudo-second-order kinetics fitting was more suitable for the U(VI) elimination process. The greatest uranium adsorbing capacity of UiO-66-NH 2 @LZU1 (180.4 mg g −1 ) was observed to exceed the UiO-66-NH 2 (108.8 mg g −1 ) and COF-LZU1 (65.8 mg g −1 ), which reached the excellent hybrid effects. Furthermore, FT-IR and XPS analyses confirmed that the most nitrogen-containing group from COF-LZU1 and oxygen-containing group of UiO-66-NH 2 could be combined with U(VI). In addition, electrostatic interaction was also a mechanism during the removal process. This work displayed that UiO-66-NH 2 @LZU1 was a prospective hybrid material for radioactive waste remediation. The compound method and application mentioned in this work had provided a theoretical basis for designing and developing multi-functional composite adsorbents, which contributed to the development of new materials for radioactive wastewater treatment technologies.
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
Scientific Reports
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2024
·Vol. 14
·期 1
·1-13
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IF 3.8
Dezhakam Ehsan,Vayghan Roya Faraghi,Dehghani Sarina,Kafili-Hajlari Taha,Naseri Abdolhossein,Dadashpour Mehdi,Khalilzadeh Balal,Kanberoglu Gulsah Saydan
Nowadays, rapid and facile diagnosis of cancer using user friendly processes has attracted much attention. In this regard, an electrochemical (EC) biosensor with high sensitivity was fabricated by merging MIL156 MOF@COF nanocomposite with Au nanoparticles for the detection of CA15-3. Herein, metal clusters of MIL-156 as a Metal organic frameworks (MOF) were coated by a crystalline covalent organic frameworks (COF) through covalent bonding and created core-shell-like structures. The active part of the working electrode was modified in two consecutive steps. First, MIL-156 MOF@COF and then Au nanoparticles were electrodeposited on the glassy carbon electrode (GCE). The porosity of nanocomposite has significantly increased the surface area and improved the conductivity. Au nanoparticles also form an acceptable substrate for bonding antibodies due to their high affinity with amino groups. In addition, Au nanoparticles amplify the EC signal of the biosensor with their undeniable conductivity. Nanocomposite was characterized with XRD, SEM, and EDAX techniques. To investigate the proposed biosensor, differential pulse voltammetry (DPV) was used as an analytical technique. The CA15-3 calibration provided a linear range between concentrations of 30 and 100 nU/mL, thus expressing the powerful diagnostic potential of the designed biosensor. Furthermore, the suggested biosensor has been used in serum samples and discriminate breast cancer sufferers from healthy individuals with high confidence levels.
研究领域:
医学诊断
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材料科学
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生物传感技术
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
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2021
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IF 7.514
Quanbin Fu,Bingbing Sun,Jun Fan,Minglin Wang,Xin Sun,Geoffrey I.N. Waterhouse,Peng Wu,Shiyun Ai
A novel mixed matrix of MOF@COF hybrid was firstly formed by coating of hexahedral cage structure MOF with lightweight porous COF, and applied in dispersive solid-phase extraction of the phenoxy carboxylic acids (PCAs) from water and vegetable samples. Combined with liquid chromatography-tandem mass spectrometry, an excellent method with low limits of detection (0.69–1.79 ng·L −1 /0.002–0.006 ng·g −1 ), good reproducibility (1.32%–7.02%/1.81%–6.71%), and excellent linearities (10–1000 ng·L −1 , R ≥ 0.9955/0.04–50 ng·g −1 , R ≥ 0.9966) was established. The adsorption mechanisms deduced that the π-π interaction, hydrophobic effects, hydrogen bond, and halogen bond may promote the excellent adsorption of the PCAs. Finally, the applicability of the method was verified by spiking four kinds of water and vegetable samples with PCAs, and satisfying recoveries were obtained (between 83.3% and 104.9%).
研究领域:
分析化学
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环境科学
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食品科学
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
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2023
·
IF 9.5
Ruiwen Li,Jintao Yan,Bin Feng,Min Sun,Chuanfan Ding,Hao Shen,Jianhua Zhu,Shaoning Yu
The widespread use of antibiotics has made multidrug-resistant bacteria (MDRB) one of the greatest threats toward global health. Current conventional microbial detection methods are usually time-consuming, labor-intensive, expensive, and unable to detect low concentrations of bacteria, which cause great difficulties in clinical diagnosis and treatment. Herein, we constructed a versatile biosensing platform on the basis of boric acid-functionalized porous framework composites (MOF@COF-BA), which were able to realize highly efficient and sensitive label-free MDRB detection via fluorescence. In this design, MDRB were captured using aptamer-coated nanoparticles and the fluorescent probe MOF@COF-BA was tightly anchored onto the surface of MDRB due to interactions between boric acid groups and glycolipids on bacteria cells. Benefitting from the remarkable fluorescence performance of MOF@COF-BA, rapid and specific detection of MDRB, such as methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii (AB), was realized with a detection range of 20–108 CFU/mL (for both) and limits of detection of 7 CFU/mL (MRSA) and 5 CFU/mL (AB). The feasibility of using the developed platform to selectively detect MRSA and AB from complex urine, human serum, and cerebrospinal fluid samples was also demonstrated. This work provides a promising strategy for accurate MDRB diagnosis, avoiding serious infection using rational antibiotic therapy.
研究领域:
微生物学
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生物医学工程
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临床诊断
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Ruiwen Li,Heng Fan,Hao Shen,Shaoning Yu
Given the frequent occurrence of multidrug-resistant bacteria (MDRB), which pose a severe threat towards public hygiene, it is important to construct facile and sensitive strategies for the detection of MDRB. We developed a fluorescent/colorimetric dual-mode biosensing platform for the analysis of MDRB by integrating the remarkable peroxidase-like activity of boric acid-decorated fluorescent framework hybrid (MOF@COF) nanozyme and enhanced bacterial affinity of DNA programmable multivalent aptamer scaffold. The efficiency and sensitivity of the proposed analysis approach were dramatically increased due to richer aptamers and high-performance MOF@COF nanozyme. Compared with commonly used single recognition methods, multivalent aptamers and bacteria-affinity boric acid groups on the nanozyme surface could identify multiple sites of MDRBs to improve site utilization for ultrasensitive biosensing. The platform realized selective detection of Acinetobacter baumannii (AB) and Pseudomonas aeruginosa (PA) in two modes with consistent results. In colorimetry and fluorescence modes, the linear ranges of AB were 10 2 -10 8 and 10–10 8 CFU/mL with corresponding detection limits of 12 and 2 CFU/mL, and the linear ranges of PA were 10 2 -10 8 and 10–10 8 CFU/mL with corresponding detection limits of 10 and 3 CFU/mL, respectively. More importantly, the biosensing platform could be applied for MDRB quantification in biological specimens, including human serum, cerebrospinal fluid, and urine with remarkable recoveries (96.8–105.0%) in both modes, indicating the bright prospect of the biosensing platform for MDRB determination in clinical diagnosis.
研究领域:
生物化学
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医学诊断
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Journal of Future Foods
·
2025
·
IF 7.2
Pengfei Dong,Shuang Wu,Youfa Wang,Ning Yu,Vijaya Raghavan,Jin Wang
Sesame allergy has emerged as a public health issue due to its persistent occurrence, severe symptomatic manifestations, and widespread incidence globally. Among sesame allergens, 2S albumins (Ses i 2) is one of the widely recognized allergens, and its precise detection is urgently needed to prevent sesame-related allergies. In this work, a composite structure was designed and synthesized by combining metal ion self-assembled metal organic frameworks (MOFs) and imine constructed covalent organic frameworks (COFs) (represented by MOF@COF), which constructing a high-sensitivity sensing system for identification and detection of Ses i 2. A novel hybrid material, comprising a strategically assembled combination of UIO-66-NH 2 and TA-COF, was crafted to yield a functionalized UIO-66-NH 2 @TA-COF composite, demonstrating remarkable electrochemical performance. As a result, a significant quantity of aptamer strands can adhere to the UIO-66-NH 2 @TA-COF surface resulting from robust π-π stacking interactions. With the change in the relative concentration of Ses i 2 from 5 to 650 nM, the UIO-66-NH 2 @TA-COF sensor exhibited a low detection limit of 0.13 nM, which demonstrates its extremely high sensitivity. In addition, the UIO-66-NH 2 @TA-COF sensor exhibited excellent reproducibility, stability and specific recognition ability to Ses i 2. Therefore, this innovative sensor exhibits great potential for real-world applications in food safety.
研究领域:
生物传感器
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食品科学
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纳米技术
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分析化学
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材料科学
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过敏研究
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）