ACS Omega
·
2020
·
IF 2.87
Jiaxue Yang,Mengyuan Liao,Gaoying Hong,Shiqi Dai,Jiadi Shen,Haifeng Xie,Chen Chen
To investigate the effects of 3-aminopropyltriethoxysilane (APTES)- or (3-mercaptopropyl)trimethoxysilane (MPTS)-conditioned nanozirconia fillers on the mechanical properties of Bis-GMA-based resin composites. The conditioned fillers were characterized by Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), and thermodynamic calculations. They were then used to prepare Bis-GMA-based resin composites, whose flexural strength and elastic modulus were evaluated. The Cell Counting Kit-8 (CCK-8) assessed the composites’ cytotoxicity. The FTIR spectra of the conditioned fillers showed new absorption bands at 1569 and 1100 cm–1, indicating successful grafting of APTES or MPTS onto nanozirconia. XPS confirmed the Zr–O–Si bonds in the APTES- or MPTS-conditioned fillers at contents of 2.02 and 6.98%, respectively. Thermodynamic calculations reaffirmed the chemical binding between the two silanes and nanozirconia fillers. Composites containing the conditioned nanozirconia fillers had significantly greater flexural strengths (APTES, 121.02 ± 8.31 MPa; MPTS, 132.80 ± 15.80 MPa; control, 94.84 ± 9.28 MPa) and elastic moduli (8.76 ± 0.52, 9.24 ± 0.60, and 7.44 ± 0.83 GPa, respectively) than a control with untreated fillers. The cytotoxicity assay identified no significant cytotoxicity by composites containing the conditioned fillers. Silanes were previously considered to be unable to chemically condition zirconia to bond with resin. Inclusion of APTES- or MPTS-conditioned nanozirconia fillers can improve the mechanical properties of Bis-GMA-based resin composites without obvious cytotoxicity in this study.
研究领域:
材料科学
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牙科材料
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高分子科学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL DENTAL JOURNAL
·
2026
·Vol. 76
·期 3
·109505
·
IF 5.2
Jiawen Liu,Yidan Xu,Zhiyuan Lin,Suqing Tu,Chen Chen,Haifeng Xie
Introduction and aims This study investigated the synergistic effect of combining 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) and γ-methacryloxypropyl trimethoxysilane (γ-MPTS) in one primer on bonding to lithium disilicate ceramics. Methods A 5% ethanol solution with 10-MDP and γ-MPTS (1:1 by volume) was prepared. The mixed solutions after 24 hours, 72 hours, 7 days, and 6 months storage were characterized by Fourier transform infrared spectroscopy (FTIR). Ultraviolet-visible (UV-Vis) spectrophotometric titration monitored the intermolecular interactions and their dynamics within 30 minutes of mixing. 84 IPS e.max CAD specimens were etched with 5% HF acid and assigned to four surface pretreatment groups: control, 10-MDP, γ-MPTS, and 10-MDP+γ-MPTS. After applying RelyX Ultimate resin cement, 1-mm composite resin cylinders were bonded and light-polymerized. The bonded assemblies were then stored in water for 24 hours or aged via 6 months storage plus 5000 thermocycles before micro-shear bond strength testing. The data were analysed using multivariate analysis of variance ( P < .05). Six machine learning models including Logistic Regression, Decision Tree, Random Forest, Extra Trees, Gradient Boosting, and Extreme Gradient Boosting were employed to evaluate the feature importance influencing bond strength. Results FTIR and UV-Vis analyses indicated that 10-MDP promoted the hydrolysis and siloxane condensation of γ-MPTS, forming a stable organic-inorganic hybrid network. The combined group showed the highest initial (24.22 MPa) and aged (16.07 MPa) bond strength, with more cohesive failures. Machine learning confirmed the combined primer as the most critical factor. Conclusions The coexistence of 10-MDP and γ-MPTS in a single solvent environment provides a synergistic effect, significantly enhancing both the bonding strength and durability of glass-based ceramics. Clinical Relevance A combined 10-MDP/γ-MPTS primer stabilizes the adhesive interface and increases the durability of ceramic restorations for better long-term success.
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Xiangjie Chen,Jia Zhu,Jian Shao,Taisong Pan,Guang Yao,Min Gao,Jian Yang,Rui Zhao,Libin Huang,Tao Li,Huanyu Cheng,Yuan Lin
L-cysteine plays a significant role in numerous physiological processes in the human body health, and monitoring its level has important clinical implications. However, L-cysteine tests are limited to invasive blood drawing and a time-consuming laboratory process, which also fails to give real-time and continuous results. This study introduces a flexible electrochemical sensor based on a self-assembled monolayer (SAM) of 3-mercaptopropyltrimethoxysilane (MPTS) molecular receptor and catalytic titanium oxide-modified carbon cloth (MPTS/TiO 2 /CC). The MPTS and TiO 2 modification serve as the artificial antibody through thiol interactions and the charge transfer layer, respectively, which is further confirmed by density function theory (DFT) calculations. The flexible L-cysteine sensor based on MPTS/TiO 2 /CC shows a wide linear range of up to 500 µ m and an ultra-low limit of detection of 0.046 µ m . A sweat patch consisting of an electrochemical sensing unit, a laser-fabricated microfluidic channel, and a miniaturized electrochemical workstation affords real-time monitoring of L-cysteine detection in dynamic environments and reveals the strong correlation between sweat and blood L-cysteine concentrations. The introduction of molecular receptors and band alignment may offer a general way of designing sensitive, specific electrochemical sensors for point-of-care diagnosis.
研究领域:
生物传感器
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纳米技术
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分析化学
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生物医学工程
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材料科学
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电化学
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可穿戴设备
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健康监测
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产品关联
DOI
高影响因子
Nanoscale
·
2019
·Vol. 11
·期 19
·9362-9368
·
IF 6.97
Peng-Fei Guo,Xi-Ming Wang,Meng-Meng Wang,Ting Yang,Ming-Li Chen,Jian-Hua Wang
Boron-titanate monolayer nanosheets were prepared through a scalable step by step intercalation approach for anchoring 3-mercaptopropyltriethoxysilane (MPTS) on the surface. MPTS provides clickable sites with 4-vinylphenylboronic acid (VPBA) via a thiol–ene (TE) click reaction to obtain monolayer titanate nanosheets with boronic acid ligands immobilized on the surface. The nanosheets obtained are denoted as VPBA-MPTS-TiNSs, with a lateral dimension of a few dozen nanometers and with a thickness of ca. 3.5 nm. The nanosheets exhibit a superior adsorption capacity of 1669.7 mg g−1 and favorable selectivity for the adsorption of glycoproteins by employing immunoglobulin G (IgG) as the protein model. The adsorbed IgG is thereafter readily collected by using 0.1% (m/v) cetane trimethyl ammonium bromide (CTAB) as the eluent. The practical applications of VPBA-MPTS-TiNSs are further demonstrated by the selective adsorption/purification of IgG from human serum.
研究领域:
材料科学
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纳米技术
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生物化学
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蛋白质纯化
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）