INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Yanan Huang,Xiaotong Wang,Bodan Luo,Peng Jin,Yonghua Zheng,Changliang Xu,Zhengguo Wu
Effective control of wound bleeding and sustained promotion of wound healing remain a major challenge for hemostatic materials. In this study, the hemostatic sponge with controllable antibacterial and adjustable continuous promotion of wound healing (CMN Cu) was prepared by chitosan, aminated MXene and copper ion . Interestingly, the internal topological point-line-surface interaction endowed the CMN-Cu sponge longitudinal staggered tubular porous microstructure, combined with the lipophilic properties obtained by modified MXene, which greatly improved its flexibility, wet elasticity and blood enrichment capacity. In addition, the sponge achieved controlled release of active ingredients, which made it present highly effective antibacterial activity and long-lasting ability to promote wound healing. In vitro and in vivo experiments confirmed that CMN-Cu sponge presented high-efficient hemostatic performance. Last but not least, a series of cell experiments showed that the CMN-Cu sponge had excellent safety as a hemostatic material.
研究领域:
生物医学材料
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创伤修复
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药物释放系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
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2023
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IF 9.5
Zhenyuan Xu,Dongzhi Zhang,Zheng Li,Chen Du,Yan Yang,Bao Zhang,Wenhao Zhao
Flexible wearable sensors to monitor human movement and for electronic skins must exhibit high sensitivity, a wide detection range, and waterproof characteristics. This work reports a flexible, highly sensitive, and waterproof sponge pressure sensor (SMCM). The sensor is made by assembling SiO2 (S), MXene (M), and NH2-CNTs (C) on the backbone of melamine sponge (M). The SMCM sensor exhibits excellent sensitivity (10.8 kPa–1), an ultra-short response/recovery time (40 ms/60 ms), a wide detection range (30 kPa), and an extremely low detection limit (4.6 Pa). Benefiting from layer-by-layer self-assembly, the sensor still exhibits excellent stability after 5000 cycles. In addition, the SMCM sensor also has excellent waterproof performance (a water contact angle of 142°), enabling it to operate unaffectedly under wet conditions. The SMCM sensor can accurately detect small body movements such as pulse and swallowing while also accurately detecting finger and elbow movements. In addition, the sensor can be designed as an array to construct an electronic skin for detecting the magnitude and distribution of external pressure. This work holds great application potential in next-generation electronic skin, fitness detection, and flexible pressure sensors.
研究领域:
材料科学
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生物医学工程
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传感器技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
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2025
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IF 9.8
Yingkun Shi,Fujia Dong,Argenis Rodas-Gonzalez,Guangxian Wang,Lingfan Yang,Sichun Chen,Hao-Bo Zheng,Songlei Wang
Heavy metal ions (HMIs) pollution has become a significant food safety concern owing to rapid urbanization and industrialization. In this study, a hypersensitive electrochemical sensor based on amino-functionalized MXene and bimetallic atom MOFs nanocomposites (MXene-NH 2 @CeFe-MOF-NH 2 ) was developed and applied for the detection of HMIs. MXene-NH 2 @CeFe-MOF-NH 2 nanocomposites were obtained by incubating MXene@CeFe-MOF prepared by hydrothermal and self-assembly methods in APTES to endow them with a large amount of surface amine functional groups. The introduction of -NH 2 could lead to a coordination effect between the nanocomposites and HMIs, promoting the enrichment efficiency of HMIs on the surface of the working electrode. The sensing platform demonstrated excellent detection performance, with limit of detection (LOD) values of 0.69 nM, 0.95 nM, and 0.33 nM for Cd 2+ , Pb 2+ and Hg 2+ , respectively, which were far below the maximum residue levels specified by the Chinese standards. Furthermore, the sensor was employed to analyze representative real samples (fish, whole milk, rice, and corn) to simulate an accurate analysis in complex scenarios and successfully detect the three HMIs simultaneously.
研究领域:
食品安全
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材料科学
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分析化学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Jing Jin,Yu Ren,Hua Zhou,Yujie Hou,Peng Jin,Yonghua Zheng,Zhengguo Wu
Berries, being juicy and thin-skinned, are prone to mechanical damage and microbial contamination during transportation. Therefore, developing functional cushioning packaging becomes crucial to minimize product losses. Herein, modified MXene was used to immobilize silver nanoparticles (AgNPs) and graft trans -2-hexenal (E2H), synthesizing MXene-NH 2 /AgNPs/E2H preservative. Subsequently, the CPMAE aerogel buffer packaging was obtained by MXene-NH 2 /AgNPs/E2H, chitosan and polyvinyl alcohol, and then using to the strawberry preservation. The physical entangling, electrostatic and hydrogen bonding between chitosan and polyvinyl alcohol, as well as the interaction with MXene-NH 2 /AgNPs/E2H endow CPMAE aerogel excellent buffering properties. Besides, only about 67.40 % of E2H and 5.80 % of AgNPs were released from the CPMAE aerogel after 7 days. Although the immobilization of MXene-NH 2 significantly reduced the release rate of AgNPs and E2H, the CPMAE aerogel still had excellent antioxidant (36.5 μg FeSO 4 /5 mg) and antimicrobial (reaches 99 %) capabilities. Moreover, these features enable the CPMAE aerogel buffer packaging to have an efficient fresh-keeping effect on strawberries and extend the storage time at 4 ℃ to 12 days. This study offers a novel approach for applying chitosan aerogel in buffer and antimicrobial packaging for berries.
研究领域:
食品科学
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材料科学
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生物工程
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产品关联
DOI
高影响因子
Sustainable Materials and Technologies
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2026
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IF 9.7
Xiaohan Niu,Cong Wen,Chunjia Luo,Jincui Gu,Yixuan Ma,Luke Yan
A “separation-recovery-purification” strategy inspired by glass sponges is proposed. • The composite membrane achieves an oil/water separation efficiency of over 97.7%. • The composite membrane attains over 97% recovery efficiency for noble metal ions. • Recycled membranes gain over 97% degradation efficiency for dyes and antibiotics. • The recycled membranes display excellent antibacterial capacity. Existing MXene-based composite materials face significant challenges in combining water purification with precious metal recovery. For complex wastewater systems containing oil–water emulsions, precious metal ions, and organic dyes, there is an urgent need to develop efficient and multifunctional MXene-based composite membranes to enhance their applicability in complex aquatic environments. In this study, MXene nanosheets and NH 2 -MIL-125 were assembled into MXene/NH 2 -MIL-125 composite membranes via vacuum-assisted filtration. The optimized composite membranes exhibited excellent hydrophilicity and underwater superoleophobicity, achieving oil–water separation efficiencies exceeding 97.7% in various emulsion systems. In addition, the membranes enabled the selective recovery of Ag + , Pd 2+ , and Au 3+ ions, with recovery efficiencies above 97% for all three ions and maximum adsorption capacities of 887.86, 845.46, and 806.57 mg·g −1 , respectively. After metal recovery, the resulting M-3@Ag membrane exhibited markedly enhanced photocatalytic performance and excellent antibacterial activity. During cyclic purification tests, the composite membrane successfully implemented an integrated “separation–recovery–purification” strategy. Overall, this work provides a green and efficient approach for the treatment of complex wastewater and the sustainable recovery of precious metal resources, showing great potential for practical applications.
✓ 已验证
DOI
高影响因子
TALANTA
·
2024
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IF 5.6
Meiqing Yang,Lu Wang,Congkai Xie,Haozi Lu,Junhua Wang,Ye Li,Huimin Li,Jifei Yang,Tingting Zhang,Song Liu
Cancer antigen 125 (CA125) is the gold standard biomarker for clinical diagnosis of ovarian cancer, with a threshold value of 35 U/mL in serum. In this paper, a disposable ultrasensitive immunosensor based on Ti 3 C 2 T x -MXene/amino-functionalized carbon nanotube (NH 2 -CNT) modified screen-printed carbon electrode (SPCE) was constructed for the detection of the ovarian cancer antigen CA125. By optimizing the mass ratio of Ti 3 C 2 T x to NH 2 -CNT, Ti 3 C 2 T x /NH 2 -CNT composite with excellent electrochemical properties was prepared, which is beneficial for amplifying the initial electrochemical signal. The positively charged NH 2 -CNT effectively alleviated the stacking problem of Ti 3 C 2 T x , and its amino group also facilitated the covalent immobilization of the capture antibody. Meanwhile, chitosan (CS) with excellent film-forming ability was also used to successfully enhance the adsorption of electrode material, thus improving the stability of the sensor. In addition, CS could further enhance the current signal. The prepared immunosensor exhibited excellent performance in CA125 detection with a wide linear range from 1 mU/mL to 500 U/mL, and good selectivity, reproducibility and lomg-term stability. Furthermore, the immunosensor showed satisfactory results for the detection of CA125 in clinical serum samples, which is promising for the clinical screening, early diagnosis and prognostic examination of ovarian cancer.
研究领域:
生物传感器
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电化学
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癌症诊断
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纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
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2025
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IF 9.8
Ying Zhang,Tianya Cao,Baoqing Bai,Xu Jing,Ligang Yu,Jinhua Zhang,Tao Bo,Huilin Liu,Ying Gu,Yukun Yang
The hazard of diethylstilbestrol (DES) towards human health underscored the imperative for highly sensitive and rapid analytical technologies. Herein, a molecularly imprinted electrochemical sensor (MIECS) was innovatively constructed by incorporating the Pt nanoparticles (PtNPs)-decorated MXene/NH 2 -UiO-66 into molecularly imprinted polymer (MIP/MXene/NH 2 -UiO-66/PtNPs) for ultra-sensitive and rapid detection of DES. The introduction of NH 2 -UiO-66 effectively prevented the restacking of MXene and with the synergistic effect of PtNPs, the electrical conductivity of the sensor was significantly enhanced. MIP/MXene/NH 2 -UiO-66/PtNPs-based MIECS not only exhibited excellent electrical conductivity but also possessed the specific cavity to recognize DES. Under optimal experimental conditions, the MIP/MXene/NH 2 -UiO-66/PtNPs-based MIECS exhibited a good relationship with the concentration of DES over a wide range of 1 × 10 −11 –1 × 10 −4 mol L −1 and an extremely low detection limit (1.19 × 10 −12 mol L −1 ). This study demonstrates the judicious design of ternary composite via hetero-interface engineering in the construction of MIECS, providing a new idea for electrochemical sensing.
研究领域:
分析化学
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纳米技术
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电化学
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材料科学
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环境监测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）