JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2017
·
IF 4.233
Yi He,De Bin Jiang,Jie Chen,De Yi Jiang,Yu Xin Zhang
In this research, MnO 2 nanosheets on montmorillonite (MnO 2 nanosheets@MMt) was synthesized by one-pot hydrothermal method and characterized by X-ray diffraction, Fourier transform infrared spectra , nitrogen adsorption and scanning electron microscopy. It was found that honeycomb-like MnO 2 nanosheets vertically grew on the surface of montmorillonite. MnO 2 nanosheets@MMt exhibited high methylene blue (MB) removal rate, which reached 97.7% within 5 min under the condition of pH 2, MnO 2 nanosheets dosage of 0.1 g L −1 and initial dye concentration of 10 mg L −1 . Additionally, the influencing factors such as pH value, amount of MnO 2 nanosheets@MMt, and MB concentration were also investigated in this paper. Results showed the MB degradation process was correlated with pH value, and the MnO 2 nanosheets@MMt achieved MB removal rate of 92.8% within 5 min under pH 11 because of its absorption capacity of MB. The kinetics of the adsorption process complied with the Pseudo-second-order model. The Langmuir model was found to be the most suitable for describing the experimental equilibrium data of MnO 2 nanosheets@MMt. The MnO 2 nanosheets@MMt showed high adsorption capacity of 363.63 mg g −1 for MB dye. The oxidative decomposition of MB was conducted in the presence of MnO 2 nanosheets@MMt in the low pH, finding that the lower the pH was, the faster the degradation rate was. This research demonstrates that MnO 2 nanosheets@MMt has potential applications in wastewater treatment .
研究领域:
环境科学
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材料科学
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Xiang Ran,Zhen Liu,Zhenzhen Wang,Fang Pu,Jinsong Ren,Xiaogang Qu
High sensitive detection and monitoring of miRNAs in living cells have obtained considerable attention for clinical diagnosis of diseases. However, there are still enormous challenges for developing new method of quantification of miRNA in vivo. Herein, an intelligent MnO 2 -carried catalytic DNA machine (MCDM) was constructed for direct visualization of MicroRNAs in vivo with high selectivity and extremely low detection limit. MnO 2 nanosheets were used as a degradable carrier to introduce the DNA machine into cells. Benefiting from the enhanced permeability and retention (EPR) effect, the MnO 2 -carried probes could accumulate in tumor tissue, realizing a direct visualization of low concentration of miR-21 in the tumor of living animals in situ.
研究领域:
生物化学
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分子生物学
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医学诊断
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Chemistry
·
2021
·
IF 5.221
Tang Shurong,Liu Qiao,Hu Jie,Chen Wei,An Fengping,Xu Hui,Song Hongbo,Wang Yi-Wei
In this paper, we developed a quick, economical and sensitive colorimetric strategy for copper ions (Cu2+) quantification via the redox response of MnO2 nanosheets with glutathione (GSH). This reaction consumed MnO2 nanosheets, which acted as a catalyst for the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to a blue product (oxTMB). In the presence of Cu2+, the GSH was catalyzed to GSSG (oxidized glutathione), and the solution changed from colorless to deep blue. Under the optimum conditions, the absorption signal of the oxidized product (oxTMB) became proportional to Cu2+ concentration in the range from 10 to 300 nM with a detection limit of 6.9 nM. This detection system showed high specificity for Cu2+. Moreover, the system has been efficaciously implemented for Cu2+ detection in actual tap water samples. The layered-nanostructures of MnO2 nanosheets make it possess high chemical and thermal stability. TMB can be quickly oxidized within 10 min by the catalyzing of MnO2 nanosheets with high oxidase-like activity. There is no need of expensive reagents, additional H2O2 and complicated modification processes during the colorimetric assay. Therefore, the strategy primarily based on MnO2 nanosheets is promising for real-time, rapid and highly sensitive detection of Cu2+ under practical conditions.
研究领域:
分析化学
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环境科学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Li Huang,Shangying Qin,Yuanjin Xu,Shiqi Cheng,Jin Yang,Yilin Wang
MnO 2 nanosheets (MnO 2 NSs) were prepared and used as both oxidant of 3, 3′, 5, 5′- tetramethylbenzidine (TMB) and recognizer of UA, a simple colorimetric approach for sensitive detection of uric acid (UA) was established. In the medium of weak acid, MnO 2 NSs exhibited strong oxidation capacity and could oxidize colorless TMB to generate a blue oxidation product (oxTMB) with an absorbance signal. However, the introduction of UA could inhibit MnO 2 NSs - mediated TMB oxidation and reduce the formation of oxTMB, resulting in the blue fading and the absorbance weakening. Under the conditions of incubation time 20 min, pH 3.0, TMB 0.5 mM, and MnO 2 NSs 50 μM, the decrease in absorbance was linearly dependent on UA concentration in the range of 0.5–30.0 μM with a detection limit of 0.21 μM. Furthermore, the approach has been applied for determining UA in human urine samples with recoveries between 93.1 and 102.4 % and relative standard deviation less than 3.0 %.
研究领域:
分析化学
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生物医学
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产品关联
DOI
高影响因子
Current Analytical Chemistry
·
2020
·Vol. 16
·期 6
·744-752
·
IF 1.365
Luo Kuan,Jiang Xinyu
Background: Diabetes Mellitus (DM) is a major public metabolic disease that influences 366 million people in the world in 2011, and this number is predicted to rise to 552 million in 2030. DM is clinically diagnosed by a fasting blood glucose that is equal or greater than 7 mM. Therefore,
the development of effective glucose biosensor has attracted extensive attention worldwide. Fluorescence- based strategies have sparked tremendous interest due to their rapid response, facile operation, and excellent sensitivity. Many fluorescent compounds have been employed for precise analysis
of glucose, including quantum dots, noble metal nanoclusters, up-converting nanoparticles, organic dyes, and composite fluorescent microspheres. Silicon dot as promising quantum dots materials have received extensive attention, owing to their distinct advantages such as biocompatibility, low
toxicity and high photostability. Methods: MnO2 nanosheets on the Si nanoparticles (NPs) surface serve as a quencher. Si NPs fluorescence can make a recovery by the addition of H2O2, which can reduce MnO2 to Mn2+, and the glucose can thus be monitored based on the enzymatic conversion
of glucose by glucose oxidase to generate H2O2. Therefore, the glucose concentration can be derived by recording the fluorescence recovery spectra of the Si NPs. Results: This probe enabled selective detection of glucose with a linear range of 1-100 μg/mL and a limit of detection of
0.98 μg/mL. Compared with the commercial glucometer, this method showed favorable results and convincing reliability. Conclusion: We have developed a novel method based on MnO2 -nanosheet-modified Si NPs for rapid monitoring of blood glucose levels. By combining the highly sensitive
H2O2/MnO2 reaction with the excellent photostability of Si NPs, a highly sensitive, selective, and cost-efficient sensing approach for glucose detection has been designed and applied to monitor glucose levels in human serum with satisfactory results.
研究领域:
生物医学工程
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分析化学
·
糖尿病研究
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yang Liu,Xinyu Sun,Ying Wang,Shiqing Zhang,Fang Liu,Shaokai Ma,Jun Zhang,Ying Li,Yanming Xue,Chengchun Tang
Birnessite (δ-MnO 2 ), inspired by biological photosynthesis, holds promise as oxygen evolution reaction (OER) catalysts in water electrolysis for clean energy. Given that Mn 3+ serves as the active sites, various strategies have been employed to increase the Mn 3+ content to boost the OER activity. To surpass the limitations of the traditional adsorbate evolution mechanism (AEM), we have adopted an electrochemical reduction method to introduce metallic Ni and enrich oxygen vacancies onto δ-MnO 2 nanosheets. The resulting Ni/MnO 2 v /CC exhibits exceptional OER performance, with a reduction in overpotential by 190 mV (from 478 mV to 289 mV) at 10 mA cm −2 and a Tafel slope as low as 45 mV dec -1 , indicating accelerated catalytic activity. Experimental and theoretical analyses attribute this enhancement to a transition from the traditional AEM to lattice oxygen mechanism (LOM) mechanism. Moreover, the dual modification also enhances electronic conductivity, electrochemical surface area, and charge transfer ability of δ-MnO 2 . Our work offers a pathway to overcome conventional limitations in OER electrocatalysts, applicable not only to Mn-based catalysts but also to a range of other transition metal oxides.
研究领域:
能源材料
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电化学
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纳米科学
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产品关联
DOI
高影响因子
Nanoscale
·
2019
·Vol. 11
·期 27
·13058-13068
·
IF 6.97
Jiapei Gu,Xiangqian Li,Zhan Zhou,Wanqiang Liu,Kai Li,Jinwei Gao,Ying Zhao,Qianming Wang
A natural resource such as peony flower has been employed for the first time as a new carbon precursor to prepare green-emitting carbon nanodots (CDs). The emission peak is situated at 523 nm and the excitation wavelength can be extended to the visible light range (452 nm). Due to the formation of CD–MnO2 nanocomposites, the emission intensity of CDs is sharply reduced as a consequence of Förster resonance energy transfer (FRET). Moreover, glucose can be recognized due to the enzymatic conversion of glucose by glucose oxidase to generate H2O2. The MnO2 nanosheets are reduced to form Mn(II) ions, and the fluorescence of CDs can be recovered. The fluorescence intensity has been improved linearly based on the increasing concentration of glucose (0.5–250 μM) with a detection limit as low as 0.18 μM. This strategy gives a new selection of eco-friendly precursors in carbon nanomaterials and such a consecutive recognition process provides valuable insights for bio-analysis.
研究领域:
材料科学
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生物分析
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2020
·
IF 4.613
Xin Tan,Pu Zhang,Cuiying Ye,Yuanhong Min,Qianwen Li,Yi Wang
Development of new methods for dopamine (DA) assay has attracted continuous attention because it serves a vital role in clinical treatment of neurological diseases such as depression, schizophrenia, and Parkinson's disease. Herein, we design a carbon dots (CDs)-MnO 2 nanosheets platform for rapid and sensitive detection of DA in pharmaceutical products. The photoluminescence of CDs can be quenched by MnO 2 nanosheets via inner filter effect (IFE) because the absorption of MnO 2 nanosheets fully covered the excitation and emission bands of CDs. However, DA can transform MnO 2 nanosheets into Mn 2+ ions, resulting in the elimination of the IFE and recovery of the photoluminescent signal. This sensing platform shows a selective and sensitive response to DA in the range of 1–30 μM, with a detection limit of 100 nM. The presented IFE-based strategy gives a new insight on development of label-free, selective and sensitive optical methods for drug assay.
研究领域:
分析化学
·
生物医学
·
药物分析
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Jiesong Tan,Yiqing Zeng,Jiahao Chen,Yutang Kang,Jiangxiao Qiao,Feng Zhang,Feng Han,Zhaoxiang Zhong,Weihong Xing
Oily particulate matter (PM) filtration faces the problems of high pressure drop and difficult regeneration. Herein, vertical arrays of MnO 2 nanosheets was assembled on Zr doped TiO 2 (Zr-TiO 2 ) nanofibers to construct a core–shell structure MnO 2 @Zr-TiO 2 (CSMT-x) catalytic membranes for highly efficient oily PM filtration and decomposition. The confining effect of the ultrathin MnO 2 nanosheets enhances PM capture efficiency, and the increase of effective contact area between MnO 2 and oily PM accelerate the decomposition of oily PM. The optimized CSMT-3 catalytic membrane exhibited high gas permeability and redox capacity, outperforming the Zr-TiO 2 (Bare T) membrane with over 99.97 % PM filtration efficiency and a low pressure drop at the temperatures of 25–425 °C. The catalytic decomposition of PM prevented the accumulation of particles on the membrane surface, which inhibited the formation of cake layer. Therefore, the CSMT-3 membrane exhibited a slight increase in pressure drop (less than 120 Pa) even after 120 h long-term filtration. This work may contribute to the development of advanced multifunctional membranes for purification of oily PM.
研究领域:
材料科学
·
环境工程
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产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2019
·Vol. 8
·期 16
·3542-3549
·
IF 5.047
Mohamed Ibrahim Halawa,Fengxia Wu,Muhammad Nadeem Zafar,Islam M. Mostafa,Abubakar Abdussalam,Shuang Han,Guobao Xu
In this work, a glutathione (GSH) sensing nano-platform using lucigenin as a fluorescent probe in the presence of MnO2 nanosheets was reported for the first time. Unlike the earlier fluorescent detection systems based on MnO2 nanosheets, which depend on Förster resonance energy transfer (FRET) or the dynamic quenching effect (DQE), the mechanism of the quenching process of MnO2 nanosheets on lucigenin fluorescence was attributed mainly to a static quenching effect (SQE) with a minor contribution of the inner filter effect (IFE). A double exponential fluorescence decay of lucigenin was obtained in various MnO2 nanosheet concentrations as a result of their SQE and IFE. Based on this phenomenon and taking advantage of the redox reaction between GSH and MnO2 nanosheets, we have developed a switch-on sensitive fluorescent method for GSH via the recovery of the MnO2 nanosheet-quenched fluorescence of lucigenin. A good linearity range of 1.0–150.0 μM with a low limit of detection (S/N = 3) of 180.0 nM was achieved, revealing the higher sensitivity for GSH determination in comparison with the previously reported MnO2 nanosheet-based turn-on fluorescent methods. The developed fluorescent nano-platform exhibits excellent selectivity with successful application for GSH detection in human serum plasma, indicating its good practicability for GSH sensing in biological and clinical applications.
研究领域:
分析化学
·
生物医学工程
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2016
·
IF 5.886
Wenyue Gao,Zhongyuan Liu,Liming Qi,Jianping Lai,Shimeles Addisu Kitte,Guobao Xu
Glutathione (GSH) is a crucial antioxidant produced endogenously and plays key roles in biological systems. It is vitally important to design simple, selective, and sensitive methods to sense GSH and monitor changes of GSH concentration. In this work, the cathodic electrochemiluminescence (ECL) of lucigenin in the presence of MnO2 nanosheets at a glassy carbon electrode was utilized for GSH detection. GSH can reduce MnO2 nanosheets into Mn2+ which can obviously inhibit the ECL of lucigenin. The ECL inhibition efficiencies increase linearly with the concentrations of glutathione in the range of 10 to 2000 nM. The detection limit for GSH measurement is 3.7 nM. This proposed method is highly sensitive, selective, simple, fast, and cost-effective. Moreover, this approach can detect GSH in human serum samples with excellent recoveries, which indicates its promising application under physiological conditions.
研究领域:
分析化学
·
生物医学工程
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Yanlin Zheng,Fei Li,Xiaohui Zhu,Min Wang,Yuantao Wen,Tao Zeng,Wukun Zhong,Chao Xing,Chunhua Lu
Photodynamic therapy (PDT) holds great promise for treating various types of cancer. However, its clinical advancement is hindered by the intrinsic hypoxic tumor microenvironment, which reduces PDT efficacy, and safety concerns related to the biological specificity of photosensitizers. Here we constructed a MnO 2 nanosheet based DNA tetrahedron-photosensitizer (TMPyP4) nanoplatform (TPM), which integration with tumor targeting (aptamer), gene drugs (DNAzyme) and photosensitizer agents for enhanced PDT. Once the TPM entered cancer cells through aptamer targeting, the MnO 2 nanosheet reacts with endogenous acidic and H 2 O 2 to generate Mn 2+ and oxygen (O 2 ), thereby alleviating the tumor hypoxic. Subsequently, TMPyP4 further converts the generated O 2 into singlet oxygen ( 1 O 2 ) under near-infrared light, enhancing PDT efficacy both in vitro and in vivo. Specifically, the generated Mn 2+ activates the DNAzyme and accelerate tumor target mRNA cleavage, resulting in effective PDT-gene synergistic therapy for tumors. This work offers novel perspectives on advancing precise and highly effective gene-PDT systems.
研究领域:
生物医学工程
·
肿瘤学
·
纳米医学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）