Applied Materials Today
·
2019
·
IF 8.013
Chao Fang,Peijian Yan,Zhaohui Ren,Yifan Wang,Xiujun Cai,Xiang Li,Gaorong Han
A variety of approaches have been investigated in the development of photothermal (PTT) and photodynamic (PDT) therapies for cancer treatment. However, when used in isolation, both PTT and PDT suffer from intrinsic drawbacks, resulting in unsatisfactory therapeutic efficacy. We describe here, a multifunctional nanoplatform, enabling the effective combination of PTT and PDT, triggered by a single 808nm-NIR light. This platform is based on MoO 2 nanoparticles, which can effectively transform NIR light into heat. By attaching molecules of indocyanine green (ICG), a hydrophilic and biocompatible NIR-mediated photosensitizer, to the surface of the particles, both photothermal and photodynamic effects can be achieved. Using an in vitro study with 4T1 cancer cells, we have demonstrated that irradiating the particles with 808nm NIR can trigger ROS production and create heat within cells. Both mechanisms acting synchronously are likely to result in superior in vivo efficacy in tumor phototherapy.
研究领域:
肿瘤学
·
纳米医学
·
生物材料学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS
·
2024
·Vol. 24
·期 13
·4320
·
IF 3.4
Min Zhang,Yi Han,Ting Liu,Hongguang Jia
High temperature represents a critical constraint in the development of gas sensors. Therefore, investigating gas sensors operating at room temperature holds significant practical importance. In this study, coal-based porous carbon (C-700) and coal-based C/MoO2nanohybrid materials were synthesized using a simple one-step vapor deposition and sintering method, and their gas-sensing performance was investigated. The gas-sensing performance for several VOC gases (phenol, ethyl acetate, ethanol, acetone, triethylamine, and toluene) and a 95% RH high-humidity environment were tested. The results indicated that the C/MoO2-450 sample sintered at 450 °C exhibited excellent specific selectivity towards acetone at room temperature, with a response value of 4153.09% and response/recovery times of 10.8 s and 2.9 s, respectively. Furthermore, the C/MoO2-450 sample also demonstrated good repeatability and long-term stability. The sensing mechanism of the synthesized materials was also explored. The superior gas-sensing performance can be attributed to the synergistic effect between the porous carbon and MoO2nanoparticles. Given the importance of enhancing the high-tech and high-value-added utilization of coal, this study provides a viable approach for utilizing coal-based carbon materials in detecting volatile organic compounds at room temperature.
研究领域:
材料科学
·
环境科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2018
·
IF 5.116
Lizhen Zeng,Xiaofen Chen,Hongying Li,Juan Xiong,Meihua Hu,Xin Li,Weishan Li
A novel composite, polydopamine-modified Mo 2 C/MoO 2 nanoparticles (HD-Mo 2 C/MoO 2 ), as anode electrocatalyst for microbial fuel cells (MFCs), is synthesized via carbon thermal reduction and following in situ polydopamine modification. The physical and electrochemical characterizations show that Mo 2 C/MoO 2 nanoparticles can be well dispersed through polydopamine modification and the resulting HD-Mo 2 C/MoO 2 exhibits excellent electrocatalytic activity compared with unmodified Mo 2 C/MoO 2 . The MFC using HD-Mo 2 C/MoO 2 as anode electrocatalyst achieves a maximum output power density of 1.64 ± 0.09 W m −2 , which is 39% higher than that using Mo 2 C/MoO 2 (1.18 ± 0.08 W m −2 ) as anode electrocatalyst. This excellent performance is attributed to modification of PDA, HD-Mo 2 C/MoO 2 shows better hydrophilicity and electrocatalytic activity toward the direct oxidation of bacterial metabolites than unmodified Mo 2 C/MoO 2 .
研究领域:
生物化学
·
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
Canadian Journal of Chemistry
·
2020
·Vol. 99
·期 3
·
IF 1.171
Jianfa Chen,Tianxiang Jin,Hangchun Deng,Jie Huang,Guangyuan Ren,Yong Qian
In this work, MoO2@NPGA nanocomposites were successfully prepared via a simple hydrothermal and calcination route. The as-prepared MoO2@NPGA composites exhibit a synergistic effect between MoO2 and N,P-codoped graphene aerogels, which can significantly improve the electrochemical performance of the MoO2@NPGA electrodes. Moreover, the results also proved that the mass loading of MoO2 has a huge effect on the electrochemical properties of MoO2@NPGA composites. With an appropriate amount of MoO2, the MoO2@NPGA composite shows a high specific capacitance (335 F g−1 at 1 A g−1) and excellent cycle stability (capacitance remains at 88% after 6000 cycles). Furthermore, the assembled symmetric supercapacitor displays a high energy density of 23.75 W h kg−1 at a power density of 300 W kg−1 and can maintain an energy density of 17.1 W h kg−1 when the power density reaches up to 6005 W kg−1.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS RESEARCH BULLETIN
·
2017
·
IF 2.446
Jun Xiang,Zhipeng Wu,Xueke Zhang,Shanshan Yao
A flexible carbon nanofiber membrane (NFM) containing uniformly dispersed MoO 2 nanoparticles is facilely fabricated via electrospinning and subsequent controlled reduction-carbonization. This NFM is used directly as a binder-free anode in lithium-ion batteries (LIBs). The self-standing carbon/MoO 2 (C/MoO 2 ) NFM electrode has a good capacity retention, a satisfactory rate capability and a high reversible capacity of 811 mAh g –1 after 100 cycles at a current density of 100 mA g –1 , which is superior to most other MoO 2 -based anodes. The superior electrochemical properties of the resultant C/MoO 2 NFM are attributed to the cooperative effects from the excellent conductivity of the carbon nanofiber matrix, the high electrochemical performance of MoO 2 , the unique one-dimensional nanofiber structure and the three-dimensional porous network structure. The present C/MoO 2 NFM may be an attractive candidate as an anode material for LIBs.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
BIOMACROMOLECULES
·
2024
·
IF 5.5
Jianjun Guo,Liang Yao,Xianqing Wang,Rijian Song,Bo Yang,Daochao Jin,Jianjun Guo,Guohua Wu
Bacterial infections in chronic wounds, such as bedsores and diabetic ulcers, present significant healthcare challenges. Excessive antibiotic use leads to drug resistance and lacks precision for targeted wound treatment. Our study introduces an innovative solution: a near-infrared (NIR) and pH dual-responsive hydrogel patch incorporating regenerated silk fibroin (RSF) and molybdenum dioxide (MoO2) nanoparticles (NPs), offering enhanced mechanical properties, precise drug release, and superior antibacterial efficacy. The dual-responsive hydrogel patch allows for precise control over antibiotic release triggered by NIR light and pH fluctuations, enabling tailored treatment for infected wounds. First, the pH-responsive characteristic matches the alkaline environment of the infected wound, ensuring on-demand antibiotic release. Second, NIR exposure accelerates antibiotic release, enhancing wound healing and providing additional antibacterial effects. Additionally, the patch further blocks bacterial infection, promotes wound repair, and degrades in sync with the healing process, further bolstering the efficacy against wound infections.
研究领域:
生物医学工程
·
材料科学
·
药剂学
·
伤口护理
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）