Materials Today Chemistry
·
2024
·
IF 6.7
Jinyu Wang,Qianqian Qiao,Yuqi Feng,Yuhao Guo,Tao Liao,Linwei Li,Ying Kuang,Bingbing Jiang,Ziqiang Xu,Cao Li
In cancer treatment, although prodrugs have been developed to overcome obstacles such as undesirable pharmacokinetic performance and serious off-target toxicity of most chemotherapeutics, the combination of prodrugs with nanotechnology could be used to overcome the shortcomings of conventional prodrug strategies and facilitate more efficient drug delivery and accumulation of anticancer prodrugs at specific sites/tissues. Phototherapy is a method that uses near-infrared (NIR) light to achieve local and non-invasive tumor therapy. The combination of chemotherapy and phototherapy has shown many therapeutic advantages, including synergistic therapeutic effects and the reduction of toxic and side effects of drugs through dose reduction. In this work, a hydrazone linkage was reported to conjugate Ti 3 C 2 T x MXene nanosheets with doxorubicin hydrochloride (DOX) and methoxy poly(ethylene glycol) benzaldehyde (mPEG-CHO) through a chemical surface modification to form a two-dimensional (2D) nano-prodrug Ti 3 C 2 T x -DOX/PEG (TDP) for synergistic chemo-photothermal therapy. First, hydrazide functionalized Ti 3 C 2 T x was obtained. Then, the carbonyl group of DOX and the aldehyde group of mPEG-CHO can form a pH-responsive hydrazone bond with hydrazide-functionalized Ti 3 C 2 T x . The high surface area of Ti 3 C 2 T x could overcome the reduced drug loading caused by conjugation. Aqueous stability and biocompatibility were enhanced by the introduction of PEG, making the material capable of prolonged circulation in the body's bloodstream. By achieving excellent antitumor results with this nano-prodrug, we have added another brick to the edifice of Ti 3 C 2 T x MXene as an anticancer drug carrier, and given new vitality to the study of anticancer prodrugs combined with nanotechnology.
研究领域:
肿瘤学
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纳米医学
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药物递送系统
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Cheng Lv,Jiayan Huang,Yuang QI,Qingjie He,Yazhou Wang,Cuili Xiang,Yongjin Zou,Fen Xu,Lixian Sun
MgH₂ is one of the most promising materials for solid hydrogen storage and is environmentally friendly primarily owing to its high mass hydrogen storage density (7.6 %). However, the application and development of MgH₂ are limited by its sluggish kinetics, requiring high processing temperatures. In this study, we prepared Ni/Co-co-doped Ti 2 VC 2 bimetallic MXene nanosheets via etching and the hydrothermal method. These nanosheets were then doped into MgH₂, resulting in drastically improved hydrogen storage properties. The MgH₂-based composite hydrogen storage materials doped with 10 wt% Ni/Co–Ti 2 VC₂ (TVCNC) commenced hydrogen emission from 183 °C and could emit 6.65 wt% hydrogen at 300 °C. During the rehydrogenation test, the composites could still absorb hydrogen at 5.0 wt% within a 10 min window at a hydrogen pressure of 20 bar at 125 °C. Moreover, the hydrogen absorption and emission kinetics of the doped MgH₂ were considerably improved. This improvement could be ascribed to the significantly increased specific surface area of the MXene nanosheets after etching, which increased the number of active sites on the surface to accelerate the reaction, thereby accelerating hydrogen adsorption and emission. In addition, the migration of electrons between the multivalent Ti ions as well as between Ni and Co helped accelerate bond cleavage between magnesium and hydrogen, thereby enhancing the kinetic properties. Ni/Co co-doping produced Mg 2 Ni alloys with magnesium via hydrogen adsorption and emission, thus improving the reaction kinetics of the composites.
研究领域:
材料科学
·
能源储存
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2021
·
IF 5.909
Lei Zhang,Ke Wei,Guangyong Zeng,Qingquan Lin,Xiang Liu,Yonggang Chen,Arijit Sengupta
Membrane based separation technology has great prospects in the treatment of oily wastewater, which involves serious environmental and health concern. In the present investigation, 3-aminopropyltriethoxysilane (APTES) was used to modify MXene nanosheets and amine functionalized carbon nanotubes (ACNTs) was used to control the layer spacing of MXene followed by the fabrication of a series of APTES/MXene-ACNTs composite membranes supported on cellulose acetate (CA) by vacuum filtration. The surface morphology analysis by scanning electron microscope (SEM) and atomic force microscopy (AFM) revealed that, the composite membranes exhibited excellent hydrophilicity as well as high efficiency in oil/water emulsion separation. The rejection ratios of composite membranes for lubricating oil emulsion and vegetable oil emulsion were found to be more than 99%. Compared to the pure MXene membrane M1 (500.7 L·m −2 ·h −1 ·bar −1 ), the pure water flux of the best modified membrane APTES/MXene-ACNTs/CA (M4) reaches up to 2892.8 L·m −2 ·h −1 ·bar −1 . Moreover, the modified membrane shows good anti-fouling and anti-swelling characteristics even after several cyclic consecutive cycles. This work demonstrates a new horizon in the applications of two-dimensional membrane materials.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
Membranes
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2022
·Vol. 12
·期 2
·146
·
IF 4.562
Yuqi Nie,Chaoxin Xie,Yi Wang
The Forward Osmosis (FO) membrane was the core of FO technology. Obtaining a high water flux while maintaining a low reverse solute flux has historically been considered the gold standard for a perfect FO membrane. In a thin-film composite FO membrane, the performance of the membrane was determined not only by the material and structure of the porous support layer but also by the structural and chemical properties of the active selective layer. Researchers have selected numerous sorts of materials for the FO membranes in recent years and have produced exceptional achievements. Herein, the performance of the modified FO membrane constructed by introducing new two-dimensional nanomaterial MXene nano-sheets to the interfacial polymerization process was investigated, and the performance of these modified membranes was investigated using a variety of characterization and testing methods. The results revealed that the MXene nano-sheets played an important role in improving the performance of the FO membrane. Because of the hydrophilic features of the MXene nano-sheets, the membrane structure may be tuned within a specific concentration range, and the performance of the modified FO membrane has been significantly enhanced accordingly. The optimal membrane water flux was boosted by around 80%, while its reverse solute flux was kept to a minimum of the resultant membranes. It showed that the addition of MXene nanosheets to the active selective layer could improve the performance of the FO membrane, and this method showed promising application prospects.Keywords:forward osmosis membrane;MXene nano-sheets;water flux;reverse solute flux
研究领域:
膜科学
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纳米技术
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水处理
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DOI
PubMed
高影响因子
ACS Applied Nano Materials
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2024
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IF 5.3
Huihuang Shen,Junjun Wang,Huabo Huang,Jiayou Ji,Liang Li
The absorption of microwaves is significantly influenced by the structure of the absorber. Typically, the electromagnetic parameters can be adjusted by modifying the structure of the absorber. In this work, a novel approach is proposed to enhance microwave absorption properties by adjusting the impedance matching of MXene nanosheets. MXene/PPy hybrids with loose lamellar structure are synthesized through self-assembly of positively charged polypyrrole (PPy) and MXene nanosheets with negative charges, facilitated by electrostatic and hydrogen-bonding interactions. The impact of polymorphic PPy on the electromagnetic parameters and microwave absorption properties of MXene nanosheets is comprehensively explored. It is found that the addition of PPy with different morphologies can effectively tune the electromagnetic parameters of the MXene nanosheets. Particularly, the microwave absorption capabilities are significantly enhanced when PPy nanopaperclips are uniformly adsorbed on the surface of the MXene nanosheets. This enhancement is attributed to the favorable impedance match between PPy nanopaperclips and MXene nanosheets along with the exceptional attenuation capabilities of PPy. A minimum reflection loss (RLmin) of −47.85 dB is achieved at an ultrathin matched thickness of 1.6 mm, and the maximum effective absorption bandwidth (EABmax) is 5.01 GHz at 1.9 mm for the prepared MXene/PPy nanopaperclip hybrid with a filling rate of 20%. Furthermore, a bandwidth with 99% absorption efficiency of 15.4 GHz (2.4–18.0 GHz) can be attained when the thickness of the absorber ranges from 1.6 to 10.0 mm. It is anticipated that this work will provide valuable insights for the manufacture of high-performance microwave absorbers.
研究领域:
材料科学
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电磁学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Kaifang Wang,Danlin Chen,Jiali Tang,Zihao Hong,Zhongtai Zhu,Ziyi Yuan,Zhihong Lin,Yuqi Liu,Raphael Semiat,Xuezhong He
Membrane gas separation technologies have emerged as highly prospective avenues for the selective separation of CO 2 . In this research, a novel array of mixed-matrix membranes (MMMs) was engineered, integrating two-dimensional nanosheets of MXene, specifically Ti 3 C 2 T x , into polymers of intrinsic microporosity (PIMs) to selectively separate CO 2 from N 2 . The inclusion of Ti 3 C 2 T x nanosheets, rich in polar functional groups, significantly increases the affinity between CO 2 molecules and the fabricated MMMs. Additionally, the precise modulation of the molecular diffusion channels for CO 2 and N 2 is achievable due to the interlayer spacing between MXene layers (∼0.35 nm) within the PIM-1 matrix. This innovation is predicated on the synergistic effect of solution-diffusion and molecular sieving mechanisms that underpin the gas separation process, leading to a marked improvement in both selectivity for CO 2 over N 2 and the permeability of CO 2 . Among the series, the MMMs with a 0.5 wt% MXene display exceptional separation efficiency, achieving a CO 2 permeability of 12475.3 barrer and a CO 2 /N 2 selectivity of 32.7. Notably, all the PIM-1/MXene membranes prepared with different compositions in this study exceed the Robeson upper bound defined in 2019, indicating their substantial promise for CO 2 separation and capture in industrial applications.
研究领域:
材料科学
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环境工程
·
化学工程
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产品关联
DOI
高影响因子
CARBON
·
2024
·
IF 10.5
Liang Yin,Yiqian Wang,Ziqi Zhao,Yuyan Liu,Ningning Cao,Ting Shi,Xiaolong Zhang,Zhen Yu,Jingfeng Wang,Zhimin Fan
MXene (Ti 3 C 2 T x ) nanosheets produced through wet etching are typically obtained as low-concentration (<1 wt%) aqueous dispersions, leading to challenges like easy oxidation, high storage and transportation costs, and difficulties in direct processing. Here, we introduce a rapid and efficient technique to capture and semi-solidify single-layer MXene nanosheets using an erasable capture agent, transforming low-concentration MXene dispersions into high-solid-content (>85 wt%) semi-solids within minutes. This approach preserves the intrinsic properties of the MXene, imparts long-term stability, and enables reversible redispersibility. Importantly, the capture agent is fully removable without special treatment and can be recycled. Moreover, the method generalizes to other MXene compositions (e.g., Ti 2 CT x ) and hydrophilic two-dimensional materials such as graphene oxide. Devices fabricated from semi-solid MXene stored for extended periods exhibit excellent functionalities including infrared stealth, Joule heating, electrochemical energy storage, and electromagnetic interference shielding. This rapid capture and semi-solidification strategy significantly streamlines the transition from MXene synthesis to practical applications, paving the way for industrial-scale utilization of MXene.
研究领域:
材料科学
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化学工程
✓ 已验证
DOI
高影响因子
BIOMACROMOLECULES
·
2022
·
IF 6.978
Lilong Cao,Zhijie Zhao,Junjie Li,Yunfeng Yi,Yuping Wei
Strong mechanical performance, appropriate adhesion capacity, and excellent biocompatibility of conductive hydrogel-based sensors are of great significance for their application. However, conventional conductive hydrogels usually exhibit insufficient mechanical strength and adhesion. In addition, they will lose flexibility and conductivity under subzero temperature and a dry environment owing to inevitable freezing and evaporation of water. In this study, a tough, flexible, self-adhesive, long-term moisturizing, and antifreezing organohydrogel was prepared, which was composed of gelatin, zwitterionic poly [2-(methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) (PSBMA), MXene nanosheets, and glycerol. Natural gelatin was incorporated to enhance mechanical performance via the entanglement of a physical cross-linked network and a PSBMA network, which was also used as a stabilizer to disperse MXene into the organohydrogel. Zwitterionic PSBMA endowed the organohydrogel with good adhesion and self-healing properties. Long-term moisturizing properties and antifreeze tolerance could be achieved owing to the synergistic water retention capacity of PSBMA and glycerol. The resulting PSBMA–gelatin–MXene–glycerol (PGMG) organohydrogel exhibited high mechanical fracture strength (0.65 MPa) and stretchability (over 1000%), excellent toughness (3.87 MJ/m3), strong and repeated adhesion to diverse substrates (e.g., paper, glass, silicon rubber, iron, and pig skin), good fatigue resistance (under the cyclic stretching–releasing process), and rapid recovery capacity. Moreover, the PGMG organohydrogel showed good stability under −40 °C. The sensor based on PGMG organohydrogel could tightly attach to the human skin and real-time-monitor the motions of joints (e.g., bending of the finger, wrist, elbow, and knee) and the change in mood such as smiling and frowning. Therefore, PGMG organohydrogels have a huge potential for wearable sensors under room temperature or extreme environments.
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Zhen Nie,Kelin Peng,Lizhi Lin,Jueying Yang,Zhekun Cheng,Qiang Gan,Yu Chen,Changgen Feng
Conductive hydrogels (CHs) have drawn wide attention from the field of flexible sensor for their similarities to tissues, excellent flexibility and good electrical conductivity. However, most of the reported hydrogel-based flexible sensors display the disadvantages of poor tensile strength, low sensitivity and insufficient stability, and most of them are prepared with non-degradable synthetic polymers, which have greatly limited their application. To solve these problems, in this work, we have constructed an agar-based dynamic double cross-linked CH by the dynamic crosslinking between agar and borax via borate bonds and the hydrogen bonds between agar chains. The CH exhibits excellent electrical conductivities, tensile properties and self-healing abilities. A novel two-dimensional material, MXene nanosheet, was introduced to further improve the mechanical properties and ionic conductivity of the CH with its high ionic conductivity and ability to form hydrogen bonds with agar. The obtained Agar/Borax/MXene CH displays the excellent strength and elongation of 129 kPa and 105.1 % and the satisfying ionic conductivity of 8.14 × 10 −2 S/cm. The flexible sensor assembled with Agar/Borax hydrogel with 0.15 wt% MXene exhibits a wide strain detection range from 0 to 100 %, high sensitivity (GF≈1.520) and good stability. Our work has provided a novel strategy for the construction of green flexible sensors with good mechanical properties and high sensitivity.
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Hongshan Wang,Zhenzhen He,Qiangbin Yang,Guangyong Zeng,Zhaomei Yang,Shengyan Pu
MXene nanosheets were functionalized by introducing sodium lignosulfonate (LS) containing abundant hydrophilic groups (sulfonic acid groups and phenolic hydroxyl groups), along with the intercalation of MoS 2 nanosheets between the functionalized MXene layers. A pressure-assisted self-assembly was utilized for the fabrication of a two-dimensional (2D) MXene membrane with high water permeation and excellent dye separation characteristics. The MoS 2 @LS-MXene composite membrane has excellent pure water flux (188.1 L·m -2 ·h -1 ), which is 85% higher than that of the unfunctionalized MXene membrane, and has a good rejection effect on dye molecules (93% for Congo red (CR), and 99% for Rhodamine B (RhB)). The appropriate interlayer spacing and negative surface charge resulted low rejection of salts (4.2% of NaCl, 4.6% of Na 2 SO 4 ) in dye-salt hybrid system, consequently leading to their mutual separation. The composite membrane also exhibits excellent stability and anti-fouling ability. This study provides a simple and novel design idea for the preparation of high-performance 2D MXene membrane.
研究领域:
材料科学
·
环境工程
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产品关联
DOI
高影响因子
ACS Applied Polymer Materials
·
2023
·
IF 5
Ye Sun,Wanying Yang,Lianchun Zou,Lixian Sun,Fan Yang,Hongbo Dang,Yanhua Yang,Dong Jiang
Nanofiltration is a membrane separation technology that efficiently separates neutral/charged solutes with little energy consumption. Reusing or treating wastewater is one of the most efficient ways to help the environment. When it comes to concentration polarization, membrane fouling, and selective permeation, however, commercial thin film composite (TFC) nanofiltration membranes exhibit more severe trade-off effects. Here, we build a TFN membrane by dispersing tannic acid (TA)-functionalized MXene (Ti3C2TX) nanosheets into the aqueous phase and incorporating them into the polyamide surface layer by interfacial polymerization. The produced membrane has been shown by a number of chemical and structural investigations to be not only porous, hydrophilic, and negatively charged but also capable of constructing transport channels in the separating layer, hence lowering the barrier to mass transfer. Changes in TA/MXene ratio and MXene nanosheet concentration allowed for fine-tuning of TMNF-TFNs membrane characteristics. Specifically, the results show that the enhanced membrane has a high water flow of 16.6 L m–2 h–1 bar–1 and a high rejection rate of divalent ions (MgSO4, Na2SO4). Important for real-world applications, the TMNF-TFN membrane also displays outstanding antifouling durability and long stability.
研究领域:
材料科学
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环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED MATERIALS
·
2024
·Vol. 36
·期 24
·2400075
·
IF 27.4
Guang-Chang Xu,Yihan Nie,Hao-Nan Li,Wan-Long Li,Wan-Ting Lin,Yu-Ren Xue,Kai Li,Yu Fang,Hong-Qing Liang,Hao-Cheng Yang,Haifei Zhan,Chao Zhang,Chaofeng Lü,Zhi-Kang Xu
Designing nanocomposite hydrogels with oriented nanosheets has emerged as a promising toolkit to achieve preferential performances that go beyond their disordered counterparts. Although current fabrication strategies via electric/magnetic force fields have made remarkable achievements, they necessitate special properties of nanosheets and suffer from an inferior orientation degree of nanosheets. Herein, a facile and universal approach is discovered to elaborate MXene-based nanocomposite hydrogels with highly oriented, heterogeneous architecture by virtue of supergravity to replace conventional force fields. The key to such architecture is to leverage bidirectional, force-tunable attributes of supergravity containing coupled orthogonal shear and centrifugal force field for steering high-efficient movement, pre-orientation, and stacking of MXene nanosheets in the bottom. Such a synergetic effect allows for yielding heterogeneous nanocomposite hydrogels with a high-orientation MXene-rich layer (orientation degree, f = 0.83) and a polymer-rich layer. The authors demonstrate that MXene-based nanocomposite hydrogels leverage their high-orientation, heterogeneous architecture to deliver an extraordinary electromagnetic interference shielding effectiveness of 55.2 dB at 12.4 GHz yet using a super-low MXene of 0.3 wt%, surpassing most hydrogels-based electromagnetic shielding materials. This versatile supergravity-steered strategy can be further extended to arbitrary nanosheets including MoS 2 , GO, and C 3 N 4 , offering a paradigm in the development of oriented nanocomposites.
研究领域:
材料科学
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纳米技术
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电磁学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）