ACS Applied Polymer Materials
·
2026
·Vol. 8
·期 15
·12782-12791
·
IF 5.2
Wei Jijun,Sun Baoyu,Meng Qinghua,Zhong Wei,Yin Xueyuan,Xu Kun,Zhang Fan,Guo Jintang
Under suitable humidity and pressure conditions, the
severe corrosion
of cement caused by CO 2 can seriously damage the integrity
of wellbores and shorten the life of oil and gas wells. Smart self-repairing
materials that can plug microcracks play a vital role in cementing.
In this study, we designed a dual-effect repair agent that combined
a smart hydrogel with modified styrene–butadiene latex (SBL).
The hydrogel showed an excellent CO 2 response, swelling
with a swelling ratio of 12.4 g/g under a CO 2 atmosphere
and plugging the microcracks of cement with a repair efficiency of
80%. In addition, the modified SBL exhibited excellent flexibility
and a small particle size (approximately 200 nm), enabling it to enter
nanometer-scale cracks in cement and aggregate to form a nonpermeable
film, further increasing the repair efficiency to 92%. In addition,
cement slurries containing the prepared hydrogel and SBL exhibited
antichanneling ability with the rapid development of early-stage strength
and a short gel transition time. We believe that the prepared dual-effect
repair agent has significant potential for oil-well cementing.
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高影响因子
JOURNAL OF CONTROLLED RELEASE
·
2026
·
IF 12.4
Kexin Wen,Chenxi Zhang,Qin Fan,Jinqiao Zhang,Yuhan Mo,Junjun Huang,Songling Liu,Xin Wang,Ziliang Dong
PANoptosis, an inflammatory cell death integrating pyroptosis, apoptosis, and necroptosis, has emerged as a promising approach for tumor immunotherapy. Reactive oxygen species (ROS) generation is the predominant strategy for triggering PANoptosis. However, in solid tumors, the hypoxic microenvironment suppresses ROS production, thereby limiting PANoptosis induction. Herein, we present an in situ-formed pH-responsive injectable hydrogel enabling sequential delivery of 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) and Type I sonodynamic nanoparticles for hypoxic tumor immunotherapy. Upon intratumoral injection, the hydrogel gradually degrades in acidic conditions. DMXAA is released first, inducing vascular shutdown and aggravating tumor hypoxia. Subsequently, nanoparticles are liberated and, under ultrasound, generate abundant ROS via a Type I sonodynamic process, bypassing oxygen dependence. The ROS burst triggers tumor cell PANoptosis, leading to immunogenic cell death, promoting antigen release and dendritic cell maturation. In multiple hypoxic tumor models, this sequential approach achieved significant tumor regression, suppressed metastasis, and induced durable immune memory to prevent recurrence. Overall, our work presents an injectable hydrogel platform that integrates controlled drug release, Type I sonodynamic PANoptosis, and immune activation for enhanced antitumor immunotherapy.
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高影响因子
MOLECULES
·
2026
·Vol. 31
·期 13
·2288
·
IF 5.1
Yue Gao,Cheng Ma,Xuan Qi,Hao Yan,Nadiremu Kamaliding,Junfeng Zhang
A high-temperature-resistant plugging–inhibitor (DS) was synthesized via emulsion polymerization using styrene (St), butyl acrylate (BA), 2-acrylamide-2-methylpropanesulfonic acid (AMPS), and N-vinylformamide (NVF), with divinylbenzene (DVB) as crosslinker and ammonium persulfate (APS) as the initiator. The structure and properties were characterized by FTIR, TG, SEM, and contact angle analysis. Plugging and inhibition performances were evaluated through filtration, high-temperature high-pressure (HTHP) plugging, linear swelling, and shale recovery tests. DS exhibits spherical morphology with particle sizes of 50–100 nm and a decomposition temperature of ~297 °C, indicating good thermal stability. The addition of DS significantly reduces filtration loss; at 1.5 wt%, the API filtration loss decreases to 6 mL. Under 180 °C conditions, 1 wt% DS reduces HTHP filtration loss from 12 to 6 mL, demonstrating excellent high-temperature plugging performance. DS also effectively suppresses shale hydration, with linear swelling reduced to 1.48 mm and shale recovery increased to 64.68% at 3 wt%. These results indicate that DS possesses excellent thermal stability, plugging efficiency, and inhibition performance, offering a promising solution for wellbore stability in shale gas drilling.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 23
·e53928
·
IF 3
Jiawen Fu,Haowei Pan,Mingzhe An,Zihao Li,Hong Wang,Xinping He,Chunhai Yi
Polyvinyl alcohol (PVA) is a promising membrane material for pervaporation (PV) desalination. However, the adjustment and control of the cross-linking structure is still a challenge for PVA membrane. In this study, a novel pH-resistant PVA-based composite membrane for efficient pervaporation desalination was developed by precisely adjusting the cross-linking behavior. Vinyl alcohol-vinylamine copolymer (VA-co-VAm) containing both hydroxyl and amino groups was synthesized. Cross-linking reaction was carried out based on the Schiff base reaction between amino groups (in VAm moiety) and glutaraldehyde (GA) under alkaline conditions. Cross-linking degree of PVA selective layer was carefully controlled by adjusting the amino group content in copolymer. Results showed that membrane prepared with VA-co-VAm that containing 5 wt% N-vinylformamide (NVF) displayed superior hydrophilicity and the largest free volume fraction. Pervaporation test indicated that the modified cross-linking membrane showed good stability under extreme pH conditions. Specifically, under strong acid conditions (pH ~ 1) and alkaline conditions (pH ~ 14), the membrane showed excellent desalination performance with water flux over 12 kg/(m 2 h), and the salt rejection higher than 99.95%. Based on the above results, the prepared membrane offers a promising platform for desalination under extreme pH conditions, which shows great potential in industrial wastewater treatment.
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高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2023
·
IF 10.9
Yunbo Feng,Qian Wang,Shudong Sun,Weifeng Zhao,Changsheng Zhao
Artificial lung membranes as the core module of the extracorporeal membrane oxygenation technology (ECMO) execute the function of extracorporeal blood-gas barrier accomplishing CO 2 /O 2 exchange with blood. However, the unsatisfactory hemocompatibility and difficulty in functionalization are the prominent challenges faced by current artificial lung membrane materials. In this study, polyethersulfone (PES) composite membranes with self-anticoagulant property and high gas exchange efficient are fabricated by blending PES matrix with poly(vinylamine) (PVAm) modified carboxylic carbon nanotubes (mCNTs) and citrate-based poly(octamethylene-citrate) (POC) pre-polymers. The mCNTs construct specific gas transfer channels within the composite membranes to enhance the gas permeability, while the POC pre-polymers provide anticoagulant property based on the chelation to blood Ca 2+ and the inactivation effect to intrinsic coagulation factors. Importantly, directed by the actual ECMO gas exchange mode, we design a gas-liquid convectional circulation device that could evaluate gas exchange efficiency for the composite membranes under mimetic ECMO state. Therefore, this strategy not only proposes a new design method of advanced artificial lung membranes to solve the practical challenges in the current ECMO technology, but also establishes a scientific testing method to evaluate the gas exchange performance for new-type artificial lung membrane materials in the future.
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高影响因子
Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Yanan Wang,Yujia Cui,Qilin Gui,Qi Ouyang,Kexing Hu,Shuxian Shi,Xiaonong Chen
Rapid and effective removal of pharmaceutical contaminants (PhCs) from water through adsorptive approach remains a huge challenge due to the multiple ionization sites and lipophilic property of most PhCs. Another issue for adsorptive media is the tough trade-off problem between adsorption enhancement and fouling-resistance. Adsorptive membranes have the advantages of convenient post-treatment and huge promise in removing PhCs compared with conventional adsorbents. Herein, two types of PEG-coupled ionic grafting adsorption membranes (NVFM-H-PEG and PPM-PMA-PEG) with outstanding adsorption and antifouling performance are developed for PhCs removal. The membranes obtained shows ultra-high water flux (up to ca. 45,000 L/(m 2 h) at a pressure drop of 15 cm water gravity) and outstanding protein repulsion. According to the Langmuir model, the adsorption capacity of NVFM-H-PEG toward ibuprofen (IBU) reaches at 81.3 mg/g at 45 ℃. The large negative ΔG value (−22.0 kJ/mol) reveals the strong affinity of the positively charged NVFM-H-PEG to adsorb negative PhCs at environmental concentrations (10 µg/L). A mechanism for the excellent adsorption performance of the membranes is proposed based on the synergy of hydrophobic interactions and electrostatic interaction. After ten adsorption/eluting cycles, no detectable decrease was observed in the removal efficiency (>96%) of IBU from the river contaminated with IBU. Furthermore, high removal efficiency (totally 90.8%) could be achieved from river water multi-contaminated with five PhCs using a complex of positively charged (NVFM-H-PEG) and negatively charged (PPM-PMA-PEG) membranes. This study provides a new design strategy for effective removing PhCs from contaminated water using adsorptive membrane technique.
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高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2023
·
IF 6.1
Xiaona Huang,Hao Zhang,Xuguang Wang,Xiutian Yang,Rongzhuang Lin,Fan Zhang,Ying Liu,Kun Xu,Chao Zhou,Pixin Wang
During cementing construction, H 2 S gas leak from micro-cracks of cement ring or cementing interface, seriously damaging wellbore integrity and shortening the life of wells. Therefore, microcrack self-healing cement technology is of great significance for oil wells to maintain the durability of cement rings and adapt to complex underground environments. Herein, acrylamide (AM), acrylonitrile (AN) and N-vinylformamide (NVF) were used as functional monomers , and laponite was added to prepare Laponite-poly(acrylamide-acrylonitrile-n-vinylformamide) nanocomposite hydrogel (L-PMAN) with excellent mechanical strength as micro-crack repair agent for gas-triggered cementing cement sheath. Considering the difference of chemical environment in the process of wellbore cement slurry sealing and subsequent micro-fracture plugging, different structural units were selected to design amphoteric structure. The construction of zwitterionic structure makes it exhibit excellent swelling behavior in salt solution while maintaining 80% of the original mechanical strength. More importantly, after adding L-PMAN powder,cement stone (C 1 ) can achieve good repair of microcracks under the trigger of H 2 S within 3 days, and the maximum gas breakthrough pressure can reach 2.5 MPa, indicating the great potentials of the L-PMAN for plugging microcracks in cement sheath.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Xiaoxiao Wan,Zhihao Rong,Kaixuan Zhu,Yumin Wu
With the rapid development of the textile industry, a large amount of dyeing wastewater discharge has caused great harm to the ecological environment. In this work, a dual-network, composite hydrogel adsorbent with excellent mechanical properties, good reusability, and large adsorption capacity was prepared by introducing chitosan cross-linked polyvinylamine into the N , N ′-methylenebisacrylamide cross-linked polyacrylic acid network. The dual cross-linking network gave the hydrogel excellent mechanical properties with maximum tensile stress and strain up to 1.9 MPa and 920 %. The adsorption capacity of methylene blue on hydrogel was up to 596.14 mg/g. In addition, the prepared hydrogel exhibited good reusability, and their adsorption efficiency remained above 85 % in five consecutive cycles. The adsorption behavior was well fitted by Pseudo-second-order kinetics and the Langmuir equation, indicating that the hydrogel was chemisorbed to the dye as a monolayer. The adsorption mechanism analysis showed that the electrostatic interactions and hydrogen bonding between the functional groups of the hydrogels and methylene blue molecules contributed to the good adsorption capacity. Overall, the synthesized composite hydrogels could be used as an efficient adsorbent for the removal of methylene blue dye, particularly from textile industry wastewater.
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PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2022
·
IF 10.53
Yunbo Feng,Qian Wang,Lunhao Zhi,Shudong Sun,Changsheng Zhao
Artificial lung membrane as extracorporeal blood-gas barriers could execute similar functions as human alveoli, whereby accomplish blood gas exchange process, providing imperative life support for patients with cardiopulmonary failure. However, the gas exchange performance for current membranous modules is restrained to the dense polymer matrix with low CO 2 permeability. Meanwhile, it has long been difficult to balance the contradiction between haemorrhagic risk generated by heparin systemic anticoagulation and thrombogenesis during extracorporeal blood circulation. Here, inspired by the natural mammalian alveoli, a biomimetic consecutive gas exchange network (CGEN) is constructed on porous PES substrate by using aperture-modulated UIO-66-NH 2 nanoparticles and hydrophilic CO 2 -affinitive polymer matrix to simulate the physiological structures and gas exchange features of human alveoli in vitro. The porous MOF particles within CGEN establish the main gas exchange channels, which not only enhance the total gas permeation, but also improve the CO 2 /O 2 permselectivity to 13.17, approaching to the level of natural alveoli. Additionally, the prepared composite membrane with good hemocompatibility could effectively inhibit the formation of thrombus and provide a reliable local self-anticoagulation state during extracorporeal blood circulation. Overall, this biomimetic thin film composite membrane could provide new ideals for the preparation of advanced artificial lung membrane.
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高影响因子
Journal of Materials Chemistry A
·
2021
·Vol. 9
·期 46
·26127-26134
·
IF 12.732
Xiangyu Li,Qilin Gui,Yen Wei,Lin Feng
Superwetting porous membranes are highly desirable for purifying oily wastewater discharged from industrial and domestic sources. However, the sustainability of this technology remains challenging due to its incapability of eliminating residual soluble oils in post-purified water. The critical limitation that the filtrate cannot meet stringent emission standards is neglected by previously reported studies. Herein, nanostructured superwettable skins are developed to provide filtration membranes with the comprehensive performance of soluble oil removal. According to a newly proposed separation mechanism of unlockable-hydration hydrophobic assembly, membranes are employed to separate various surfactant stabilized oil-in-water emulsions with ultralow residual oil content (<0.5 mg L−1), superior permeation flux (∼1400 L m−2 h−1), and robust reusability for long-term work solely under the driving force of gravity (∼1.5 kPa). This study should provide distinctive insights into the functional wetting modification and pioneer a promising strategy to design high-performance separation materials for thorough oily wastewater remediation.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2023
·
IF 4.2
Jiawen Fu,Chenxi Dong,Miaoli Hao,Xinping He,Dongyun Wu,Chunhai Yi,Suitao Qi
In this study, a highly hydrophilic membrane was developed by an interfacial reaction using two aqueous monomers for pervaporation (PV) desalination. Two water-soluble monomers, procyanidin (PC) and vinyl alcohol-vinylamine copolymer (VA-co-VAm), were applied to prepare membranes on hydrophobic polyvinylidene difluoride (PVDF) membranes through interfacial reactions. Catechol groups of PC were oxidized to quinone groups under weakly alkaline conditions, which could react with amino groups of VA-co-VAm to form a cross-linked network. The PVDF membrane was first dipped into a PC aqueous solution to form a thin PC liquid layer on the surface. Accompanied by the PC liquid layer, the PVDF membrane was then dipped into the VA-co-VAm solution to induce the interfacial reaction. The composition and structure of membranes were observed, and the effects of different factors on the desalination performance were investigated. By applying two aqueous monomers in the interfacial reaction process, the obtained thin membrane showed good hydrophilicity with a water contact angle of less than 42°. A water flux of 42.16 kg/(m2·h) at 60 °C was obtained by treating a feed solution (3.5 wt % NaCl). At all testing procedures, the salt rejection remained higher than 99.99%. Besides, the membrane displayed superior stability over 48 h of testing. According to the above results, the prepared membranes showed great potential in the process of PV desalination. This work provides a new approach for highly permeable PV membrane preparation through an interfacial reaction using two water-soluble materials.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Bo Wang,Jiayou Xu,Jixiao Wang,Song Zhao,Xinlei Liu,Zhi Wang
Gas separation performance of mixed matrix membrane heavily depends on the pore structure of the nanofillers. Metal-organic frameworks (MOFs) are promising platform materials for constructing molecular-selective pores for specific applications. In this work, deliberately-selected polymers with CO 2 affinity (PVAm, Pebax and PEI) are employed as pore regulators to manipulate the pore chemistry and size of MOF UiO-66 nanoparticles and consequently control gas transport rate of CO 2 and N 2 molecules. The branched polymer (polyethyleneimine (PEI)) grafted UiO-66, denoted as UKI, is beneficial to enhancing the membrane selectivity. The UKI doped Pebax/mPSf membranes exhibit CO 2 /N 2 selectivity up to 278, 6.5 times of the bare Pebax/mPSf membranes. Meanwhile, the CO 2 permeance is boosted from around 690 to 1120 GPU (1 GPU = 10 −6 cm 3 (STP)·cm −2 ·s −1 ·cmHg −1 = 3.35 × 10 −10 mol m −2 s −1 ·Pa −1 ). The block copolymer (poly(ether block amide) (Pebax)) grafted UiO-66, denoted as UKX, is conducive to increasing the membrane permeance. The UKX doped Pebax/mPSf membranes exhibited CO 2 permeance up to 1683 GPU, 2.45 times of the bare Pebax/mPSf membranes. Meanwhile, CO 2 /N 2 selectivity increased from around 42 to 146. Additionally, excellent pressure-resistant property and outstanding stability are observed under simulated flue gas .
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高影响因子
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