Processes
·
2025
·Vol. 13
·期 3
·922
·
IF 2.8
Xu Chen,Xiangpeng Zhu,Cheng Gan,Yigang Li,Diren Liu
The stability of cement slurries under high-temperature conditions poses a significant engineering challenge in cementing operations. This study explored the development of a novel tetrameric thermosensitive thickening polymer (TTSTC) as a solution to this problem. Aqueous free radical polymerization was employed to synthesize the polymer. The base monomers 2-acrylamido-2-methylpropanesulfonic acid (AMPS) and acrylamide (AM) were employed, in conjunction with the long-chain thermosensitive monomers octadecyldimethylallylammonium chloride (C18DMAAC) and N-vinylpyrrolidone (NVP). The optimal synthesis conditions were determined by orthogonal experiments as follows: monomer molar ratio (AM:AMPS:C18DMAAC:NVP) = 15:10:5:5, initiator concentration of 16 wt%, cross-linker concentration of 0.45 wt%, pH 6, and polymerization temperature of 60 °C. The chemical structure of TTSTC was characterized by Fourier transform infrared spectroscopy (FT-IR), proton nuclear magnetic resonance (1H-NMR), gel permeation chromatography, scanning electron microscopy, Zeta potential, and particle size measurement. The results verified the successful synthesis of the target polymer. Its thermal stability, thermosensitive thickening behavior, and salinity resistance were systematically investigated. Furthermore, the impact of TTSTC on the settling stability, rheological characteristics, and compressive strength of cement paste was assessed. The experimental findings demonstrated that TTSTC displayed noteworthy thermosensitive thickening properties at temperatures up to 279 °C, pH values ranging from 11 to 13, and NaCl/CaCl2concentrations between 0.05 and 0.5 g/L. The optimal performance of TTSTC was observed at mass fractions ranging from 0.6 to 0.8 wt%. When incorporated into the slurry at 0.6–1.0 wt%, TTSTC significantly improved the slurry settling stability, thickening properties, and 28d compressive strength at elevated temperatures compared with the control. When comparing the temperature-sensitive thickening performance of the newly developed treatment agent with that of the commercially available xanthan gum thickener, the results showed that for the cement slurry system containing the new treatment agent at a mass fraction of 0.6%, the reduction in consistency was 30.9% less than that of the cement slurry system with xanthan gum at a mass fraction of 0.6%. These findings indicate that TTSTC has the potential to function as a highly effective additive in cementing operations conducted in extreme environments, thereby enhancing the stability and dependability of such operations.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 12
·4815-4822
·
IF 3.069
Jin Wang,Mengde Deng,Yahui Xiao,Wentao Hao,Chengfeng Zhu
Polyelectrolytes with good ionic conductivity and dielectric properties have been shown to be superior for supercapacitors and other power storage devices. Here, a cationic polyelectrolyte with blended poly(N-vinylpyrrolidone-co-diallyl dimethyl ammonium chloride) (P(NVP-co-DMDAAC)) copolymer and poly(vinyl alcohol) (PVA) was prepared via the interpenetrating polymer network (IPN) technique. The dielectric properties, ionic conductivity, mechanical properties and the influence of the thicknesses of hydrogel membranes on capacitance properties were studied. The introduction of the cationic DMDAAC monomer and polar PVA increased the integrated performance of the PNVP hydrogel. In comparison with PVA, PNVP, and P(NVP-co-DMDAAC), P(NVP-co-DMDAAC)/PVA IPN hydrogel exhibited higher permittivity of 27.19 at 1 kHz frequency and the maximum ionic conductivity of 3.66 × 10−2 S cm−1 at 10% PVA dosage. The tensile strength increased with the increase in the PVA content. The specific capacitances of P(NVP-co-DMDAAC)/10PVA increased with the decrease in the thickness of the hydrogel membrane and its retention rate was 95% after 1000 cycles.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
LIFE SCIENCES
·
2025
·
IF 5.1
Wenzhe Kong,Xudong Ding,Zhaoyu Wang,Lu Lu,Saijun Fan
As a common side effect of radiotherapy, radiation-induced intestinal injury (RIII) greatly affects the prognosis of patients and the efficacy of radiotherapy. Current therapeutic strategies for RIII are still very limited. Thus, the identification of effective radioprotective agents is of great importance. NVP-AUY922 is an HSP90 inhibitor with favorable anti-inflammatory and antioxidant activities. It has been proven to mitigate radiation-induced lung injury. However, its effects on the alleviation of RIII remain unclear. In this study, our data indicated that NVP-AUY922 remarkably increased the survival rate after radiation exposure. NVP-AUY922 treatment could enhance the viability of intestinal stem cells (ISCs) and promote the recovery of the small intestine. In addition, it also inhibited intestinal inflammation and reshaped the gut microbiota structure. We found that the radioprotective effect of NVP-AUY922 is partially dependent on EPHX1. In addition, NVP-AUY922 could attenuate dextran sulfate sodium (DSS)-induced colitis and promote intestinal barrier recovery. Thus, our results suggest that NVP-AUY922 contributes to the amelioration of intestinal injury after radiation exposure, which offers a new approach for the prevention of RIII.
研究领域:
肿瘤学
·
放射生物学
·
药理学
·
胃肠病学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Oncology Letters
·
2020
·Vol. 20
·期 6
·1-1
·
IF 2.311
Hao Zhu,Yuhuan Shi,Xiuxiu Jiao,Gang Yang,Rong Wang,Yongfang Yuan
Cisplatin resistance is an obstacle for the effective treatment of non‑small cell lung cancer (NSCLC). The combined use of two or more chemotherapeutic agents displays advantages for the clinical treatment of drug‑resistant lung cancer. The present study aimed to assess the synergy of the dual PI3K/Akt/mTOR signaling pathway inhibitor NVP‑BEZ235 and cisplatin, a chemotherapeutic agent, on proliferation, apoptosis, cell cycle arrest and protein expression in cisplatin‑resistant NSCLC A549/diamminedichloroplatinum resistance (DDP) cells. Cell proliferation was determined by performing Cell Counting Kit 8 and colony formation assays. Combination index (CI) was used to assess the combinatorial effects of NVP‑BEZ235 and cisplatin. Cellular apoptosis and cell cycle arrest were detected via flow cytometry. Western blotting was performed to evaluate protein expression levels relative to β‑actin. Cisplatin and NVP‑BEZ235 displayed the strongest synergy (CI50=0.23) at the mass ratio of 10:1. The half inhibitory concentrations of cisplatin and NVP‑BEZ235 at 10:1 were 1.53 and 0.15 µg/ml, respectively. Compared with the control group, the combination of cisplatin and NVP‑BEZ235 induced cell apoptosis and inhibited colony formation. Furthermore, compared with the control group, phosphorylation of Akt and p70S6 Kinase was significantly inhibited and cell cycle was arrested at G0G1 phase in the combination treatment group. The expression levels of drug efflux proteins, such as multidrug resistance‑associated protein 1 and ATP‑binding cassette sub‑family G member 2, were significantly decreased when A549/DDP cells were treated with a combination of cisplatin and NVP‑BEZ235 compared with the control group. Collectively, the present study indicated that the combined treatment of cisplatin and NVP‑BEZ235 displayed synergistic antitumor effects on drug‑resistant A549/DDP cells, by which the antiproliferative effects may occur via inhibition of the PI3K/Akt/mTOR signaling pathway and downregulation of drug efflux.
研究领域:
肿瘤学
·
药理学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Optical Materials
·
2025
·
IF 7.2
Suwen Cheng,Yupeng Zhang,Ying Chu,Yanchen Wang,Yuan Xie,Chen Yu,Jingjin Dong,Jiupeng Cao,Fangfang Wang,Wei Huang,Aifei Wang,Tianshi Qin
Hybrid halide perovskite films are becoming increasingly efficient in various applications, but several challenges still remain to be overcome. In this study, thermally polymerized additive N-vinyl-2-pyrrolidone (NVP) is utilized to tune the crystallization and orientation of mixed organo-metal perovskite films. Using in situ spectroscopy, it is demonstrated that NVP plays a crucial role in prolonging the crystallization process and separating the nucleation and crystal growth by forming an NVP-precursor intermediate phase. Additionally, the intermediate adduct effectively passivates defects, reduces nonradiative recombination, improves crystallinity, and enhances the transmission of charge carriers. NVP-containing perovskite light-emitting diodes (PeLEDs) are subsequently developed that exhibit stable and bright green luminance exceeding 240 000 cd m −2 . These findings provide valuable insights into manipulating the crystallization behavior of mixed organo-metal perovskite films.
研究领域:
材料科学
·
光电技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 139
·期 38
·e52905
·
IF 3.057
Jin Wang,Jingjing Bian,Bin Pu,Yuanlu Wang,Mengde Deng
Polyelectrolyte hydrogel used for supercapacitors have the roles of both electrolyte and separator, the morphology and the strength of gel polyelectrolyte (GPE) are the keys for ionic transport properties therein. Here, the P(NVP- co -SPE)/polyvinyl alcohol (PVA) IPN hydrogel was prepared by photopolymerization and thermal polymerization, respectively. The influences of preparation method on morphology, mechanical strength and electrochemical performances were studied. Photopolymerized IPN GPE (UV-GPE) exhibits a special regular microphase separation structure, and therefore has outstanding strength-toughness and better electrochemical performance. The tensile strength and the toughness increased intensively from the 6.2 MPa and 3.4 MJ m −3 of thermal polymerized IPN GPE (TH-GPE) to 28.5 MPa and 24.9 MJ m −3 , respectively. The maximum swelling ratio of UV-GPE is increased from 327% of TH-GPE to 630%. The ionic conductivity of UV-GPE increased from 4.29 × 10 −2 S/cm of TH-GPE to 5.82 × 10 −2 S/cm. UV-GPE has higher response current and specific capacitance. It also has the obviously better charge–discharge symmetry and cycling stability, and the capacity retention rate is still 92.3% after 1000 cycles. Thus, it brings out the fast, eco-economic photopolymerization method is an effective way to prepare high-performance polyelectrolyte hydrogel.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
CARBON
·
2025
·
IF 11.6
Jin Chen,Pei Liu,Kai Xu,Zhilei Hao,Guohui Tang,Changtian Zhu,Zixuan Ding,Shuai Yin,Zhiqiang Li,Zhen Ding,Yi Wang,Zhanpeng Liu,Siwen Yu,Xing Xin,Fenghua Liu
Na 3 V 2 (PO 4 ) 3 (NVP) material has evolved as a significant candidate for electrode materials in the development of sodium-ion batteries. However, the low conductivity of NVP material leads to low cycling performance, limiting their application in high-efficiency battery materials. To address this issue, this work proposes a novel strategy for materials design through constructing 3D network carbon-coatings on the surface of NVP materials. The carbon-coatings are achieved via a combination of sol-gel technique and heat treatment using pyrolytic carbon (C), carbon nanotubes (CNTs) and graphene (GN). In comparison to NVP@C, the electrochemical properties of NVP@C/GN, NVP@C/CNTs, and NVP@C/GN/CNTs have shown improvements. Among these, NVP@C/GN/CNTs exhibit the most outstanding electrochemical performance in the half-cell test. Specifically, this material demonstrates exceptional cycling stability, with a capacity of 92 mAh g −1 that can be maintained even after 800 cycles at a high-rate performance of 10C, with an attenuation of 10.6 %. The enhanced electrochemical performance is attributed to the specific ternary carbon-coating conductive structure, which significantly shortens the diffusion paths of Na + ions and electrons within NVP, resulting in improved Na + ion and electron transport kinetics. This study provides a new design paradigm for improving the conductivity of cathode material for sodium-ion batteries.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
·
2017
·
IF 1.9
Wanlu Zhang,Guangji Li,Yinlei Lin,Liying Wang,Shuqing Wu
We aimed to introduce hydrophilic sulfobetaine-type zwitterionic groups to macromolecular chains of copolymers to construct novel copolymer hydrogels with anti-protein-fouling performance that could be used as soft contact lens (SCL) materials. Using hydroxyethyl methacrylate (HEMA), N-vinyl pyrrolidinone (NVP) and sulfobetaine methacrylate (SBMA) as comonomers, several copolymer hydrogels with different SBMA contents, poly(HEMA-NVP-SBMA), are synthesized via radical copolymerization in an aqueous phase. Surface chemistry, structural morphologies, water contact angle (WCA), equilibrium water content (EWC), visible light transmittance and tensile mechanical properties are investigated. The prepared hydrogels exhibit a closed-type porous structure. With increasing SBMA content in the comonomer mixture, the prepared copolymer hydrogel pore size gradually increases up to the micron level, WCA tends to decrease, EWC tends to increase, and visible light transmittance slightly increases, but their tensile mechanical properties decline. The amounts of protein Lyz and BSA adsorbed on the copolymer hydrogels and on commercially available EASY DAY® SCLs as a control are also determined by protein adsorption tests. The amount of protein adsorbed on the copolymer hydrogel decreases with increasing SBMA content. For the hydrogel prepared using the comonomer mixture with 5.0 wt % SBMA, the amount of adsorbed Lyz is 0.91 μg/cm2, which corresponds to only 56.8% of the amount adsorbed on EASY DAY® SCLs. Thus, novel SCL materials with high water content and excellent anti-protein-fouling performance were efficiently constructed by introducing sulfobetaine-type zwitterionic groups into a traditional polymer hydrogel system.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2020
·Vol. 137
·期 35
·49016
·
IF 2.52
Guancheng Jiang,Kai Wang,Yinbo He,Lili Yang,Xinliang Li,Yu Deng
To meet the increasing requirement of stabilizing shale under high-temperature situation with the use of water-based drilling fluids (WBDFs), the high-performance shale stabilizer is an urgent need. In this study, an amphoteric copolymer of AM/DMDAAC/NVP (APC) was synthesized by acrylamide (AM), dimethyl diallyl ammonium chloride (DMDAAC), and N -vinylpyrrolidone (NVP) and used as a high temperature-resistant shale stabilizer. The Fourier transform infrared spectroscopy and nuclear magnetic resonance spectroscopy confirmed the successful synthesis of APC. The inhibitive performance of APC was systematically evaluated and compared with three other commonly used shale stabilizers, including the anionic potassium polyacrylamide (KPAM), cationic poly dimethyl diallyl ammonium chloride (PD), and amphoteric polymer FA367. The results demonstrated that APC displayed excellent performance on the linear swelling test, hot-rolling recovery experiment, and shale immersion test. Furthermore, APC combined the advantages of high shale recovery percentages of PD and maintaining shale pellet integrity of KPAM, avoiding the drawbacks of enormous filtration volume of PD and low shale recovery percentages of KPAM. These great properties indicated that APC would be suitable as a shale stabilizer in WBDF to drill high-temperature shale formation.
研究领域:
化学工程
·
材料科学
✓ 已验证
DOI
高影响因子
Inorganic Chemistry Frontiers
·
2020
·Vol. 7
·期 5
·1289-1297
·
IF 5.958
Zhaoyang Wang,Jinmei Liu,Zijuan Du,Haizheng Tao,Yuanzheng Yue
Na3V2(PO4)3 (NVP) features a three-dimensional open structure, which allows fast migration of Na+ ions, and thus, NVP is a superior cathode material for sodium ion batteries. However, the application of the NVP cathode is limited by its low electronic conductivity. To overcome this limitation, we developed an NVP nanocomposite cathode by doping carbon with bromine (Br) and nitrogen (N) during the sol–gel assisted hydrothermal reaction. The Br- and N-doping leads to the formation of amorphous carbon (a-C) on the surface of NVP particles. The nanocomposite possesses multilevel structures containing both pores with different sizes and aggregated grains (200–300 nm). Since the doped N provides electrons to the carbon matrix, the electronic conductivity of the nanocomposite is enhanced. Br-Doping leads to the drop of activation energy for V4+/V5+ redox reaction. The nanocomposite cathode exhibits a high reversible capacity of 41 mA h g−1 at 10C. Both the superior rate and cycling performances could be attributed to the synergistic effect of the multilevel structure and amorphous carbon.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2017
·
IF 3.133
Hui Xiao,Xiaobing Huang,Yurong Ren,Haiyan Wang,Jianning Ding,Shibiao Zhou,Xiang Ding,Yuandao Chen
Na 3 V 2 (PO 4 ) 3 /nitrogen doped carbon (NVP/CN) composites have been fabricated by a simple and low cost solid-state technique using folic acid as the carbon-nitrogen source. The structure, morphology and electrochemical performance of NVP/CN composites coated with various carbon-nitrogen layer contents are well investigated. The results reveal that the NVP/CN composite with 3.3 wt% carbon-nitrogen exhibits the largest specific surface area, with a uniform carbon-nitrogen layer thickness of approximately 2 nm. When tested as cathode material for sodium ion battery , NVP/CN composite with 3.3 wt% carbon-nitrogen displays an outstanding high rate properties with the discharge capacity of 95 and 91 mAh g −1 at 10 and 20 C, respectively, and long cycle life up to 3000 times even at a high rate of 10 C due to the smallest charge-transfer resistance and highest Na + diffusion coefficient . The results suggest that folic acid is a promising carbon-nitrogen source for construction of NVP/CN and other cathode materials.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
Small
·
2023
·
IF 13.3
Na Guo,Zhi Peng,Wenjie Huo,Yuehua Li,Shude Liu,Ling Kang,Xianwen Wu,Lei Dai,Ling Wang,Seong Chan Jun,Zhangxing He
Aqueous Zn-ion batteries (AZIBs) attract intensive attention owing to their environmental friendliness, cost-effectiveness, innate safety, and high specific capacity. However, the practical applications of AZIBs are hindered by several adverse phenomena, including corrosion, Zn dendrites, and hydrogen evolution. Herein, a Zn anode decorated with a 3D porous-structured Na 3 V 2 (PO4) 3 (NVP@Zn) is obtained, where the NVP reconstruct the electrolyte/anode interface. The resulting NVP@Zn anode can provide a large quantity of fast and stable channels, facilitating enhanced Zn ion deposition kinetics and regulating the Zn ions transport process through the ion confinement effect. The NASICON-type NVP protective layer promote the desolvation process due to its nanopore structure, thus effectively avoiding side reactions. Theoretical calculations indicate that the NVP@Zn electrode has a higher Zn ion binding energy and a higher migration barrier, which demonstrates that NVP protective layer can enhance Zn ion deposition kinetics and prevent the unfettered 2D diffusion of Zn ions. Therefore, the results show that NVP@Zn/MnO 2 full cell can maintain a high specific discharge capacity of 168 mAh g −1 and a high-capacity retention rate of 74.6% after cycling. The extraordinary results obtained with this strategy have confirmed the promising applications of NVP in high-performance AZIBs.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）