Na-CMC polyurethane microspheres were prepared with isophorone diisocyanate and polyethylene glycol and sodium carboxymethyl cellulose as main materials. Ibuprofen used as a model drug and core material was coated into microspheres. The microspheres morphologies and the composite physical states were investigated using optical microscopy, scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopy. Optical microscopy and scanning electron microscopy observations revealed that had a good spherical structure. Results from FTIR and DSC suggested that the Na-CMC had been successfully introduced to the polyurethane molecular chain, Na-CMC polyurethane microspheres had good thermal stability, and heating weightlessness was less than 2% in the 300°C. Na-CMC polyurethane microspheres carried drug were pH sensive and the drug release rate under different pH value were different.
Richard M. Kasomo,Hongqiang Li,Huifang Zheng,Qian Chen,Xiaoqing Weng,Akisa D. Mwangi,Wu Ge,Shaoxian Song
In this paper, Na-CMC was studied as a depressant for almandine during flotation separation of rutile using cationic surfactant, octadecyl amine polyoxyethylene ether (AC1815) as a collector. Results of micro-flotation studies suggested that Na-CMC was considered as a selective depressant for almandine. Zeta potential and X-ray Photoelectron Spectroscopy (XPS) were used to elucidate the interaction mechanism between the minerals (rutile and almandine) and Na-CMC. The XPS analysis results show that there was both the chemical and hydrogen bonding in the interaction between almandine and Na-CMC. Zeta potential measurements indicate that, the adsorption of carboxylic groups on the almandine ferrous active sites, takes place with chemisorption which in turn depressed the almandine floatability. Contact angles results on the other hand shows that the floatability of almandine was adversely affected after being treated with Na-CMC, while the same depressant did not have any pronounced negative effect on the floatability of rutile.
危险品化学品经营许可证（带存储）