SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2020
·
IF 3.232
Hongqi Chen,Wen Wang,Changchun Ji,Lun Wang
The core–shell NaGdF 4 :Yb,Er@NaGdF 4 :Yb,Nd upconversion nanoparticles (UCNPs) were successfully obtained with the method of co-precipitation, and the water-solubility of UCNPs was improved by the ligand exchange reaction between nitrosyl tetrafluoroborate (NOBF 4 ) and nanoparticles. The IR-783 dye with negative charge and NOBF 4 -UCNPs with positive charge can bind together by electrostatic action to sensitize UCNPs through the energy transfer from IR-783 to UCNPs. However, with the presence of Na 2 S (a commonly used H 2 S donor), a highly selective reaction between H 2 S and IR-783, which destoried the structure of IR-783 and blocked the energy transfer, thus led to the quenching of luminescent intensity. Based on this, a sensing system for determination of H 2 S has been constructed successfully. The linear range of H 2 S detection by this system is 0.5–15 μM, and the detection limit is 34.17 nM. Furthermore, the dye-sensitized core–shell NaGdF 4 :Yb,Er@NaGdF 4 :Yb,Nd upconversion nanoprobe was applied to real sample analysis with satisfactory results.
研究领域:
分析化学
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纳米技术
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Guangdong Wu,Juanqin Xue,Dashi Lei,Yanyan Zhou,Zhaoyuan Cao,Kang Ren,Qiang Bi,Zhihua Leng
Currently, upconversion nanoparticles (UCNPs) based photocatalysts have been extensively developed to improve solar energy utilization. However, the mechanisms underlying interfacial energy migration of upconversion photocatalyst remain unclear. Herein, a promising composite photocatalyst with complementary properties is designed by integrating β -NaGdF 4 :Yb 3+ /Er 3+ (NGFYE), CdS and multi-walled carbon nanotubes (MWCNTs). The morphology, structure and chemical properties of NGFYE@CdS/MWCNTs ternary photocatalyst are characterized. In addition, the existence of Förster resonance energy transfer process in NGFYE@CdS/MWCNTs photocatalysts, i.e., the migration of excitation energy from Er 3+ − 4 S 3/2 excitation level and higher excitation level (e.g., Er 3+ − 2 H 11/2 ) to CdS nanoparticles, was further confirmed by density functional theory (DFT) calculations. The optimized NGFYE@CdS/MWCNTs photocatalyst presents 71.65 % and 35.29 % degradation of tetracycline hydrochloride (TCH) and ciprofloxacin (CIP) under λ ≥ 800 nm irradiation for 3 h, respectively. This work not only illustrates the interfacial energy migration mechanism between NGFYE and CdS, but also provides insights for the rapid construction of heterojunction materials with efficient energy transfer interfaces.
研究领域:
材料科学
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环境科学
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理论化学
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产品关联
DOI
高影响因子
CRYSTENGCOMM
·
2015
·Vol. 17
·期 31
·5900-5905
·
IF 4.034
Bin-Bin Ding,Kun Liu,Fu Zhang,Yang Wang,Sheng Cheng,Yang Lu,Hai-Sheng Qian
Upconversion fluorescent nanostructures with controlled sizes and morphologies have attracted much attention due to their potential and important applications in bioimaging, photodynamic therapy, solar cells and so on. In this work, we describe a facile successive process to fabricate β-NaGdF4:Yb,Er nanocrystals coated with an ultrathin layer of CaF2 with enhanced upconversion fluorescence and stability. The as-prepared β-NaGdF4:Yb,Er@CaF2 nanoparticles were investigated by X-ray diffraction (XRD), transmission electron microscopy (TEM, JEM 21000), fluorescence spectroscopy (Hitachi High-Technology Corporation, F-2700) and inductively coupled plasma atomic emission spectroscopy (ICP-AES). The as-prepared core–shell nanoparticles show enhanced upconversion fluorescence and superior magnetic resonance (MR) relaxivity. In addition, the as-prepared β-NaGdF4:Yb,Er@CaF2 nanoparticles show enhanced chemical stability after surface functionalization and transfer into aqueous solutions.
研究领域:
材料科学
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生物医学工程
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Wei Tang,Ruo Mi,Lun Wang,Hongqi Chen
A quantitative image analysis and separation system was designed for detection of human immunodeficiency virus (HIV) related DNAs in the red region by combining of upconversion luminescence nanoprobe and magnetic beads (MBs). Carboxyl-modified NaGdF 4 :Yb, [email protected] 4 upconversion nanoparticles (UCNPs) were connected to single-stranded DNA to form a reporter probe, while carboxyl-modified magnetic beads were connected to another single-stranded DNA to form a capture probe. In the presence of target HIV DNAs, NaGdF 4 :Yb, [email protected] 4 UCNPs and magnetic beads were conjugated to form UCNPs-DNA-MBs nanocomplexes through DNA-DNA heteroduplexes based on the principle of complementary base pairing. After magnetic separation, the upconversion luminescence intensity of UCNPs-DNA-MBs nanocomplexes was related to the concentration of the target HIV DNAs. The detection methods were investigated by fluorescence spectrometry and quantitative image analysis based on upconversion luminescence total internal reflection (TIR) imaging platform. Compared to the luminescence spectral analysis, the quantitative image analysis shows higher sensitivity (linear range of 0.02−30 nM and detection limit of 0.0102 nM). More importantly, this method only needs 10 μL sample and the analysis time is about 0.1 s. The method combines quantitative image analysis with magnetic separation technology, which has the characteristics of low background interference and high separation efficiency allowing for application to the field of biology.
研究领域:
分析化学
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生物技术
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纳米技术
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病毒学
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2020
·Vol. 12
·期 42
·5081-5085
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IF 2.596
Hongqi Chen,Huihui Wang,Wanying Xia,Jianguo Zhang,Lun Wang
In this work, we developed a simple and selective luminescence sensing system for detecting ascorbic acid (AA) based on NaGdF4:Yb,Er@NaYF4 upconversion nanoparticles (UCNPs) and oxidase-like CoOOH nanoflakes. When p-phenylenediamine (PPD) and oxidase-like CoOOH nanoflakes were added to the UCNPs solutions, PPD, as a typical substrate of oxidase, could be oxidized to PPDox. The luminescence intensity of UCNPs was quenched because PPDox could play a role as an energy acceptor. When AA was added to the above solution mixture, the CoOOH nanoflakes were destroyed, and then, the luminescence intensity was recovered. Under the best experimental conditions, the linear range for detection of AA was 0.8 to 280 μM, and the detection limit was 0.25 μM. Furthermore, the system could be applied to real sample analysis with satisfactory results.
研究领域:
分析化学
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纳米技术
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生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemistry-An Asian Journal
·
2022
·Vol. 17
·期 14
·e202200161
·
IF 4.839
Bo Ling,Yaguang Wang,Ruo Mi,Di Wang,Hongqi Chen,Xiaohu Li,Ye Zhang,Lun Wang
Graphical NaGdF 4 ,Yb,Er@NaGdF 4 ,Yb,Tm@NaYF 4 core@shell@shell three-layer structure of upconversion nanoparticles coated with Fe−TCPP metal-organic frameworks nanocomposite was designed and constructed for multimodal imaging and synergetic chemodynamic therapy/photodynamic therapy of tumors. Here, NaGdF 4 ,Yb,Er@NaGdF 4 ,Yb,Tm@NaYF 4 core@shell@shell three-layer structure of upconversion nanoparticles (UCNPs) coated with Fe−Tetrakis (4-carboxyphenyl) porphine (TCPP) metal-organic frameworks (Fe-MOFs) nanocomposite (UCNPs@MOFs) was designed and constructed for multimodal imaging and synergetic chemodynamic therapy (CDT)/photodynamic therapy (PDT) of tumors. The UCNPs@MOFs were successfully applied for tumor cells imaging in vitro and in vivo in near-infrared (NIR) region. The doped Gd was used as contrast agent for the magnetic resonance imaging (MRI) of mouse tumors. The luminescence in the UV-vis region was absorbed by the Fe-MOFs to produce singlet oxygen ( 1 O 2 ) for PDT. The Fe 3+ doped in the MOFs can catalyze H 2 O 2 to produce oxygen and hydroxyl radical (⋅OH). Hydroxyl radical is used in CDT and cooperates with the 1 O 2 of PDT. Based on the CDT/PDT synergistic effects, the UCNPs@MOFs nanocomposite had obviously enhanced tumor inhibitory efficiency in vivo. These results described that the asprared UCNPs@MOFs nanocomposite have great potential in the effective multimodal imaging and treatment of tumors.
研究领域:
生物医学工程
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纳米医学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MODERN OPTICS
·
2024
·
IF 1.2
Hui Ying Zhang,Wan Ying Xie,Peng Zhang,Xiao Hui Li,Zian Cheak Tiu
In this work, NaGdF4: 20%Yb, 2%Er microcrystals with varying contents of Cr3+ doping were obtained by conventional hydrothermal process. The microcrystal phase structure, morphology, upconversion luminescence mechanism, as well as temperature sensing behaviour under different treatment methods were researched. Based on the thermally coupled 2H11/2 and 4S3/2 levels of Er3+ and the dependence of fluorescence intensity ratio (FIR) on temperature, the optical temperature sensing behaviour of micrometer crystals were experimentally demonstrated. The NaGdF4: 20%Yb, 2%Er, 7%Cr microcrystals treated with high-temperature annealing show the best temperature sensing behaviour within the temperature span of 298–498 K. NaGdF4: 20%Yb, 2%Er, 7%Cr microcrystals with high temperature annealing presented the feasibility and promising properties for optical temperature sensing. The endeavour of emerging materials could lay the groundwork for future sustainable photonics engineering industrial growth.
研究领域:
材料科学
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光学工程
✓ 已验证
产品关联
DOI
高影响因子
CRYSTENGCOMM
·
2020
·Vol. 22
·期 38
·6330-6338
·
IF 3.117
Chunyan Cheng,Yueshan Xu,Gejihu De,Jianxun Wang,Wei Wu,Yuexing Tian,Shasha Wang
Rare-earth doped upconversion nanoparticles (UCNPs) have attracted wide-ranging interest due to their potential applications in bioimaging and biolabeling, where a high emission intensity and small particle size are needed. However, common synthesis processes can be somewhat complex or require additional reactants, and the use of small-size NPs is limited by their weak luminescence intensity. In this work, uniform, monodisperse ∼5 nm β-NaGdF4:20% Yb/2% Er NPs were synthesized via a simple one-pot synthesis method in the high boiling-point solvents 1-octadecene (ODE) and oleic acid (OA) using a single dose of NaF at an ultralow NaF concentration of NaF/RE = 4. The effects of NaF/RE, the reaction temperature, and the reaction time on the size and phase of the particles were investigated. High-quality β-NaGdF4:20% Yb/2% Er@β-NaGdF4:20% Yb/10% Nd core–shell NPs with a size of ∼13 nm, enhanced UC luminescence, long UC lifetimes (τ) for green (τ ≈ 150 μs) and red (τ ≈ 105 μs) emission under 980 and 808 nm excitation, revealed via lifetime imaging, and obvious emission in the near-infrared (NIR) II region were synthesized. The synthesized core–shell NPs may result in a decrease in the overheating effect and allow for a deep penetration depth when further used for bioimaging applications. This work could inspire the synthesis of other high-quality RE-doped UCNPs via adding a single dose of a small amount of NaF and could lay the foundation for the use of Gd-based UCNPs in biomedical applications.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 85
·81542-81551
·
IF 3.289
Shuwen Zhao,Wei Liu,Xianya Xue,Yushi Yang,Zhiyong Zhao,Youfa Wang,Bin Zhou
In this work, a new strategy to enhance upconversion emission has been realized for the first time, based on β-NaGdF4:Yb3+, Er3+ nanocrystals (UCNC) using tridoping with magnesium (Mg2+) ions. X-ray diffraction (XRD) and inductively coupled plasma–atomic emission spectroscopy data indicated successful incorporation of the Mg2+ ions in β-NaGdF4:Yb3+, Er3+. The effect of the Mg2+ tridopant on the crystal structure, upconversion luminescence, and paramagnetization in β-NaGdF4:Yb3+, Er3+ was investigated in detail. The red, green and violet emission intensities were clearly enhanced and the maximum emission intensities were enhanced by about 9, 6, and 7 times, respectively, by tridoping with 13.5 mol% Mg2+ ions. The possible mechanism for enhancing upconversion emission was determined by the alteration of inter-ionic distance and the distortion of crystal structure based on the XRD data. The paramagnetic property can be modulated by the introduction of Mg2+ ions and the core–shell structure, and this can be ascribed to the change in the gadolinium molar percentage. Additionally, a synergistic effect on emission intensity enhancement was observed in a Mg2+-doped core–shell structure. At last, an improved ligand exchange method has been designed to render oleic acid-stabilized 13.5 mol% Mg2+-doped UCNCs dispersible in water and their three day cytotoxicity was assayed using stem cells. It is expected that this material could be applied in biomedical nanoprobes, bioseparation, magnetic resonance imaging, and so on.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2019
·
IF 4.916
Huihui Wang,Yunyun Lu,Lun Wang,Hongqi Chen
A selective, simple and environment-friendly type fluorescence sensing platform between upconversion nanoparticles (UCNPs) and melanin-like polymer utilizing the photoinduced electron-transfer (PET) mechanism was developed. The effective fluorescence quenching of UCNPs by melanin-like polymers could detect tyramine and tyrosinase (TYR) activity through the bio-catalysed oxidation of tyramine to the melanin-like polymer products. At optimal conditions, the range of linearity in detection was 0.167–33.3 μΜ for tyramine, and the limit of detection of tyramine was 0.026 μΜ. The linear range of TYR was 0.0033–1 U·mL −1 , and the limit of detection of TYR was 0.003 U·mL −1 . Furthermore, the strategy could be applied to real sample analysis with satisfactory results.
研究领域:
生物化学
·
分析化学
·
纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF LUMINESCENCE
·
2022
·
IF 4.171
Junshan Hu,Fengyi Wang,Wei Jin,Changchun Ding
Upconversion nanoparticles (UCNPs) have great potential applications in biological imaging, medical treatment and optical sensing. However, the development of an inorganic-organic hybrid fluorescent probe to accurately detect noxious ions and scientifically assess irritation in vivo remains a challenge. Herein, we demonstrate a fluorescent nanoprobe for detecting nitrites (NO 2 − ) and assessing the irritation in jellyfish cell. The nanoprobe was assembled by linking neutral red to the surface of polyethylene glycol (PEG) modified NaGdF 4 :Yb,Er@NaYF 4 core/shell nanoparticles. The nanoprobe could efficiently capture the NO 2 − in jellyfish and simultaneously visualize the process. It's known that the intensity ratio of green to red emission (IRGRE) of neutral red modified upconversion nanoparticles increases linearly with the amount of NO 2 − increasing. Moreover, the irritation of NO 2 − was assessed in jellyfish cells using neutral red modified fluorescent nanoprobe based on cell imaging and spectrum signals, that NO 2 − has irrecoverable injury to the cells. This work based on dye-modified upconversion luminescence nanoprobe is expected to shed further light on the biological analysis and detection of ions.
研究领域:
生物成像
·
光学传感
·
医学检测
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FLUORINE CHEMISTRY
·
2017
·
IF 2.101
Songxia Yu,Zhiqiang Wang,Ruijun Cao,Lingjie Meng
In this paper, we have developed a series of rare earth fluoride nanocrystals (NCs) that can be used for multimodal imaging applications. Three highly monodisperse and water dispersible NaGdF 4 :Yb,Ln@NaGdF 4 (Ln = Er, Tm, Ho) upconversion luminescence (UCL) NCs with an average size of 75 nm were prepared using a facile and efficient microwave–assisted solvothermal reaction in ethylene glycol (EG). The morphology, crystal structures, size distributions and zeta potentials of the resulting NCs were fully characterized by transmission electron microscopy (TEM), X–ray diffraction (XRD) and Nano–ZS90 Zetasizer. The obtained NaGdF 4 :Yb,Ln@NaGdF 4 (Ln = Er, Tm, Ho) NCs could emit bright blue, green and red luminescence in water upon laser excitation at 980 nm. Furthermore, these core–shell NCs exhibited low cytotoxicity for HeLa and C9H2 cells, separately. Moreover, these NCs also displayed excellent Hounsfield units (HU) values in X–ray computed tomography (CT) imaging and high relaxivity parameters (r 1 ) in magnetic resonance (MR) imaging in vitro . Thus, these small, water–dispersible and biocompatible NCs show excellent potential as contrast agents for UCL/CT/MR multimodal imaging and other biomedical applications.
研究领域:
材料科学
·
生物医学工程
·
影像医学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）