RSC Advances
·
2017
·Vol. 7
·期 55
·34746-34754
·
IF 3.108
Ziwei Hu,Mingshan Xie,Danting Yang,Dong Chen,Jingyi Jian,Haibin Li,Kaisong Yuan,Zhengjin Jiang,Haibo Zhou
Berberine is an important anti-inflammatory drug widely used for the treatment of heart and intestinal disorders. The quantification of berberine is usually required in clinic medical assays. Herein, we report simple, fast and sensitive colorimetric visualization of berberine in human plasma using citrate-stabilized gold nanoparticles (AuNPs). Upon exposure to μg mL−1 levels of berberine, the AuNP solution exhibits a highly sensitive color change from red to blue and rapid aggregation kinetics within the initial 10 min, which can be directly seen with the naked eye and monitored by UV-vis absorbance spectroscopy. As confirmed by comparison with potential coexisting foreign substances, the presence of positively charged berberine induces the aggregation of the AuNPs owing to the electrostatic attraction and coordination interactions between the ring nitrogen atoms of berberine and the AuNPs, causing a color change of the AuNP suspension. Further evidence is that the sensitivity is significantly improved when NaHSO4 is added to promote the ligand exchange between citrate and berberine at the surface of the AuNPs. The NaHSO4-optimized AuNP system provides a simple colorimetric assay for the rapid detection of berberine in human plasma. The limit of detection (LOD) is 0.24 μg mL−1 by the naked eye and 0.06 μg mL−1 by UV-vis spectroscopy.
研究领域:
药理学
·
分析化学
·
纳米医学
✓ 已验证
DOI
高影响因子
ENERGY & FUELS
·
2020
·
IF 3.421
Zhihao Si,Miao Zuo,Wenlong Jia,Gaofeng Chen,Xing Tang,Xianhai Zeng,Lu Lin
Synthesis of a biodiesel precursor from biobased materials usually needs harsh reaction conditions such as high temperature, long time, and precious catalysts. In this article, a mild pathway was provided to directly synthesize biodiesel precursor bis(furan-2-yl)methane derivatives (BFMs) with industrial salt NaHSO4 as a recyclable heterogeneous catalyst at room temperature. Over 99% yield of bis(5-methylfuran-2-yl)methane (BMFM) was obtained after 10 min reaction with 5-methylfurfuryl alcohol and 2-methylfuran (2-MF) as the substrates. Moreover, the addition of 2-MF in this work could effectively increase the BMFM yield and restrain the side reactions; then the proposed mechanism was also put forward according to the detailed mechanistic studies. In this condensation reaction, the electron donor substitute and conjugation structure on the furan ring is essential, and the crystalline water of the catalyst also promoted the catalytic efficiency obviously. Overall, this work provides a budget and practical approach for biodiesel production from biobased materials, which exhibit the potential for industrial application.
研究领域:
化学工程
·
可再生能源
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
Chemical Engineering and Processing-Process Intensification
·
2023
·
IF 4.3
Yaping Zhang,Tongying Feng,Jingli Liu,Qingze Jiao,Bin Zhen
Glycerol is one cheap byproduct in production of biodiesel, and the ketalization of glycerol is one of the most important and effective way to increase its value and improve the sustainability of biodiesel. The ketalization of glycerol with acetone is always catalyzed by acid catalyst. In this work, NaOH was added into the reaction system during the ketalization process catalyzed by NaHSO 4 , and it was found for the first time that this process could be intensified by NaOH significantly. The acidity of acidic catalysts would affect their catalytic performance. Increasing reaction temperature and time, molar ratio of acetone to glycerol, the dosage of NaHSO 4 and molar ratio of NaOH to NaHSO 4 could favor for the ketalization, but the excessive formation of water and the evaporation of acetone would retard the reaction. The addition of NaOH could destroy the intermolecular hydrogen bond network of glycerol molecules, making the hydroxyl groups bared in free state, and increase the amount of electrophilic transition state of acetone, which help to promote the transformation of glycerol to solketal significantly. With the assistance of NaOH, the conversion rate of glycerol could even reach 97.58 % without extracting water continuously from the reaction system.
研究领域:
化学工程
·
催化
·
可再生能源
·
可持续化学
✓ 已验证
产品关联
DOI
高影响因子
SYNTHETIC COMMUNICATIONS
·
2017
·
IF 1.134
Haifei Zhang,Fengfan Zhu,Yuan Xu,Xiaoxiang Zhang,Xinbao Zhu
The synthesis of several ricinoleic acid glycol ether esters by high-pressure microwave radiation is described. Ricinoleic acid which is from castor oil reacted fastly with glycol ethers in the presence of NaHSO4 · H2O and dichloromethane (DCM) in special microwave reactor. The influences of reaction factors such as catalyst and solvent type, reaction temperature, and time were investigated and the optimal reaction conditions were obtained. The activity of catalyst had a higher performance up to the 10th cycle and the excellent values of turnover numbers and turnover frequency were obtained. Compared with the traditional esterification in reflux heating systems., the microwave-assisted process has many advantages such as shorter reaction time, less side effects, higher yield, which is a great potential for the development of green chemistry.
研究领域:
有机化学
·
绿色化学
✓ 已验证
DOI
高影响因子
ADVANCED POWDER TECHNOLOGY
·
2026
·Vol. 37
·期 9
·105402
·
IF 4.5
Siqi Jiang,Tanzila Anjum,Aimin Li
Leaching Al from fly ash (FA) represents a critical pathway for its resource recovery. Some Al is imprinted in the stable mullite structure, making it difficult to leach out. Using the conventional strong acid or alkali methods to dissolve mullite has the disadvantages of environmental hazard and inefficient Al-Si separation. This study created a low-temperature NaHSO 4 molten salt process that converts mullite into water-soluble NaAl(SO 4 ) 2 and insoluble SiO 2 , followed by the separation of Al and Si through water leaching. First, TG was used to define the temperature. Subsequently, the influence of calcination temperature, time, and the NaHSO 4 dosage was explored. Finally, the leaching behavior of Al was investigated, and the leaching kinetics were analyzed. The conversion of mullite to NaAl(SO 4 ) 2 was confirmed to be best when calcined at 350 °C for 3 h, while the molar ratio of NaHSO 4 /Al 2 O 3 was 10. Sequentially, leaching at 70 °C for 90 min with water can leach 85.28% and 0.60% of Al and Si. The leaching process conformed to the Avrami model and belonged to the interfacial reaction.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）