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Nepenthes alata
CHEMICAL ENGINEERING JOURNAL · 2022 · IF 16.744

Biomimicking integrates peristome surface of Nepenthes alata onto biliary stents tips

Mingtian Xu,Zhengjie Xu,Zhijun Jiang,Wenwen Shao,Lihao Zhang,Yufei Chen,Zhixia Dong,Cihui Liu,Weixing Zhang,Xinjian Wan

Biliary stents (BS) play an important role in the field of modern interventional therapy. However, the surface of BS is easy to cause microbial attachment, which causes serious postoperative infections and threatens the life safety of patients. Here, inspired by the microstructures of Nepenthes alata ’s peristome surface and Morpho menelaus , we presented an excellent slippery surface for BS tips by employing inverse opal colloidal crystals hydrogels. The inverse opal structure not only imparts a tunable structural color to the slippery surface but provides sufficient room for liquid absorption, such as lubricants and drugs. The slippery liquid-infused porous surfaces (SLIPS) endow the slippery surface with anti-adhesion and antibacterial properties. Due to the good temperature sensitivity of hydrogels, we can control the drug release by changing the temperature. In particular, the drug release process can be monitored through visually structural color variations. Furthermore, we also proposed a mechanism of droplet infiltration on SLIPS under the heating which is expected to be used for the smart transport of droplets. The multifunctional SLIPS BS tips also exhibit good generalization, we believe it will bring more possibilities for biliary stents.

研究领域: 生物医学工程 · 材料科学
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