MATERIALS CHARACTERIZATION
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2021
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IF 4.342
Wennan Su,Xiufang Cui,Guo Jin,Yajie Guan,Yao Zhao,Simin Wan,Changhao Liu,Yuyun Yang,Haoliang Tian
NiTi, NiTi-4Si, and NiTi-4Si-2YF 3 coatings were prepared on Ti-6Al-4V substrate by laser cladding to obtain composite multilayer protective coating for composite structure. The effects of Si and YF 3 addition on the microstructure, phase composition, microhardness , and phase transformation of the coatings were systematically analyzed. The coatings are mainly composed of NiTi, NiTi 2, and TiN phases. The addition of YF 3 results in the decrease of the dendrite TiN phase in the coating. TEM results show that the core-shell structure is observed in NiTi-4Si coating. The β -Ti phase was surrounded by the shell NiTi 2 phase. After the addition of YF 3 , the core-shell structure was found to disappear. With the addition of the Si element, the eutectic structure was found in the coatings. The eutectic structure is mainly composed of NiTi (B2) and Ti 2 Si phases. According to the SEAD result, there are crystallographic orientation relationships (ORs) between NiTi (B2) phase and Ti 2 Si phase as follows: 1 ¯ 11 B 2 / / 1 ¯ 23 Ti 2 Si . The average microhardness of the NiTi, NiTi-4Si and NiTi-4Si-2YF 3 coatings were at 468.33 HV 0.5 , 499.86 HV 0.5 , and 433.65 HV 0.5 , respectively. At the same time, the uniformity of the NiTi phase in NiTi-4Si-2YF 3 coatings is improved, which is conducive to a more complete phase transition.
研究领域:
材料科学
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表面工程
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Chao Wei,Haifeng Zhang,Ji Tan,Kui Xue,Zhiyu Hou,Rongxiang Ding,Xianming Zhang,Xuanyong Liu
NiTi alloys are widely used in the fabrication of biomedical implants, and it is essential to endow them with selective antibacterial properties to avoid implant-associated infection. In this study, nickel nitride (Ni 3 N), as a promising new inorganic nitric oxide (NO) donor, was in situ constructed on the surface of NiTi alloys through a straightforward two-step plasma immersion ion implantation (PIII) strategy. Nickel sites were first exposed by physical bombardment with argon or metal plasma, followed by reaction with nitrogen plasma to form Ni 3 N. Ni 3 N can disrupt the transmembrane proton electrochemical gradient by capturing protons to produce ammonia species (NH x ), resulting in the accumulation of reactive oxygen species (ROS) as a result of bacterial metabolic disruption. On the other hand, the generated NH x can further react with ROS to produce NO and reactive nitrogen species (RNS). As a result, the Ni 3 N films exhibited more than 99 % antibacterial efficiency against both gram-negative and gram-positive bacteria. They also demonstrated effective antibacterial properties in a rat subcutaneous implant model. In addition, the modified NiTi alloys exhibit good corrosion resistance and cytocompatibility. This study provides a green, safe, and inexpensive method for constructing metal nitride films on implant surfaces and offers new ideas for the clinical design and fabrication of novel antibacterial implants.
研究领域:
生物医学工程
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材料科学
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微生物学
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产品关联
DOI
高影响因子
Materials
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2022
·Vol. 15
·期 20
·7331
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IF 3.748
Zhiqiang He,Ze Wang,Dezhi Wang,Xinli Liu,Bohua Duan
Porous NiTi alloys were manufactured by integration of gel-casting and microwave sintering. The effects of sintering temperature on porosity, compressive strength, pore morphology and phase composition of sintered samples were researched. The results show that the porosity and the mean pore diameter of porous NiTi alloys decrease with increasing sintering temperature, whereas the content of the NiTi phase, the elastic modulus and compressive strength of sintered samples increase. When the gel body with the solid loading of 50 vol.% is microwave sintered at 1000 °C for 30 min, porous NiTi alloys are obtained with the porosity of 38.9%, the compressive strength of 254 MPa, elastic modulus of 4 GPa, and predominant phase of NiTi. The results suggest that the method is suitable for rapid preparation of large-size and complex-shape personalized products similar to human bones at a low cost.Keywords:gel-casting;porous NiTi alloy;microwave sintering;microstructure;mechanical properties
研究领域:
材料科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
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2025
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IF 6.9
Shuangjun Xi,Yijie Qiao,Lan Jiang,Jie Hu,Jie Yang,Weina Han
Bone defects caused by trauma or severe diseases present significant clinical challenges. In this study, a multifunctional, multiscale therapeutic platform based on NiTi alloy was developed, exhibiting enhanced osteointegration and antibacterial performance. Femtosecond laser direct writing was first used to create micro-grooves with periodic ripple structures, promoting osteointegration via contact guidance effects. Subsequent anodizing generated a nanostructured porous layer on this microstructure, further enhancing biocompatibility and osteointegration. Finally, a polydopamine coating was applied to facilitate the in-situ incorporation of nanosilver, imparting strong antibacterial properties while simultaneously enhancing cell adhesion. MC3T3-E1 cell adhesion and differentiation assays confirmed the platform’s robust osteogenic capacity. Additionally, the system achieved bactericidal efficiencies of 99.86 % against E. coli and 99.69 % against S. aureus . Overall, this study presents a comprehensive and effective method with high potential for bone defect repair.
研究领域:
生物材料学
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骨科学
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表面工程
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组织工程
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纳米医学
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转化医学
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产品关联
DOI
高影响因子
Materials
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2022
·Vol. 15
·期 23
·8398-8398
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IF 3.748
Ze Wang,Zhiqiang He,Bohua Duan,Xinli Liu,Dezhi Wang
Porous NiTi alloys are widely applied in the field of medical implant materials due to their excellent properties. In this paper, porous NiTi alloys were prepared by non-aqueous gel-casting. The influence of solid loading on the process characteristics of slurries and the microstructure and mechanical properties of sintered samples were investigated. The viscosity and the stability of slurry significantly increased with the growth of solid loading, and the slurry had better process characteristics in the solid loading range of 40-52 vol.%. Meanwhile, the porosity and average pore diameter of the sintered NiTi alloys decreased with a rise in the solid loading, while the compressive strength increased. Porous NiTi alloys with porosities of 43.3-48.6%, average pore sizes of 53-145 µm, and compressive strengths of 87-167 MPa were fabricated by gel-casting. These properties meet the requirements of cortical bone. The results suggest that the pore structure and mechanical properties of porous NiTi products produced by gel-casting can be adjusted by controlling the solid loading.
研究领域:
材料科学
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生物医学工程
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机械工程
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产品关联
DOI
PubMed
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
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2023
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IF 4.6
Mengxia Peng,Quanchao Zhang,Mengna Zhang,Zhiwei Yang,Yizao Wan,Xiaoyan Deng,Honglin Luo
Improved bone bonding ability and antibacterial activity are two critical requirements for implants. In this work, novel dual surface modifications of dealloying and polydopamine/silver coating on a NiTi alloy were conducted. Scanning electron microscopy (SEM) results show a porous layer with interconnected micro- and nano-pores on the dealloyed NiTi alloy. Fourier transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS) results confirm the formation of a polydopamine/silver coating on the surface of the dealloyed NiTi alloy. The silver nanoparticles (58.9 nm, in the polydopamine/silver coating) on the dealloyed NiTi alloy surface are smaller when compared with pristine NiTi alloy (73.1 nm). Moreover, the dealloyed NiTi alloy with polydopamine/silver coating exhibits better antibacterial activity against Escherichia coli (99.7%) and Staphylococcus aureus (99.4%) than pristine NiTi alloy with the same coating (97.3% and 96.5%, respectively), due to the larger surface area, higher silver content, and smaller silver nanoparticles that trigger more silver ion release. The combined dealloying and coating method is an effective way of increasing antibacterial activity of NiTi alloys. The findings presented in this work may provide a new guidance for the surface modification of NiTi implant materials .
研究领域:
材料科学
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生物材料
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表面工程
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生物医学工程
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产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2019
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IF 4.175
Xue Ma,Hao Wang,Hongwei Xie,Jiakang Qu,Xiang Chen,Fei Chen,Qiushi Song,Huayi Yin
An Electro-Assisted Powder Metallurgical (EPM) route is able to prepare porous NiTi alloys with controllable porosities and pore sizes using nickel (Ni) and titanium (Ti) powders at a temperature ranging from 850 to 950 °C. Ammonium hydrogen carbonate (NH 4 HCO 3 ) was used as a sacrificial space holder to tailor the porosity and pore size of the NiTi alloy and its properties, i.e., elastic modulus , phase transformation temperature, shape memory effect, and superelasticity . By optimizing the synthesis temperature and content of the sacrificial space holder (0–30%), the porosity (41–75%), pore size (22–174 μm ), elastic modulus (4.77–0.87 GPa) and the recovery strain (>2%) of the EPM-NiTi can meet or are close to the standard of natural bone (porosity: 30%–80%, pore size: 100–600 μm, cancellous modulus: < 3 GPa, recovery strain: > 2%). Therefore, the EPM route is promising to prepare porous Ti-based alloys for implants.
研究领域:
材料科学
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冶金学
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生物材料
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生物医学工程
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DOI
高影响因子
危险品化学品经营许可证（带存储）